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The map label for this gene is pfp [H]

Identifier: 238916031

GI number: 238916031

Start: 68499

End: 69722

Strand: Reverse

Name: pfp [H]

Synonym: EUBELI_00064

Alternate gene names: 238916031

Gene position: 69722-68499 (Counterclockwise)

Preceding gene: 238916039

Following gene: 238916026

Centisome position: 3.25

GC content: 40.77

Gene sequence:

>1224_bases
ATGGATGGTAATGTTATAGTTGGACAGTCAGGAGGACCTACTTCTGTTATCAACTCAAGTCTTGCTGGGGTATATAAGAC
AGCCATAGACAGAGGAGCTAAGAAAGTTTATGGTATGCTCCACGGTATTAAGGGACTTCTTGATGGTCAGTATGTTGACC
TTTCAGAGAAGATTAACTCAACAATGGATATTGATTTATTAAAGAGAACACCTTCATCTTATCTTGGTTCATGCAGGTAC
AAGCTTCCTGAGATAAGCGAAGACAGAGAAACATTTGATAAGATTTTCAAGATTCTTGATGATCTTGATATCAAATATTT
CTTCTATATTGGTGGTAACGACTCAATGGATACTATCAAGAAGTTATCTGATTACGCAATCGTAACCGGAAGCGATATTA
AATTCATGGGTGTACCTAAGACTATTGATAATGACTTAGCTGTTACAGACCACACACCAGGATTTGGTTCTGCTGCCAAG
TTTATCGCAGCTACTATGAAGGAAATCATCAGAGATGGTCTTGTATATGATTATCCTACAGTTACTATTGTAGAGATTAT
GGGACGTAATGCCGGATGGCTTACAGCCGCTGCTGCTCTTGCAAAGAGTGATGACTGCGAAGGTGTAGACCTTATCTACC
TTCCAGAGAAAGTATTTGATATCGACCATTTCATGGCAAGAGTTAAAGAAATTGCAGCTAAGGGCCGTTCAATGGTTATC
GCTGTTTCAGAAGGTATTAAGGTTGCTGACGGAAGATATGTATTCGAGCTTTCAGAGCATGTAGAATTCGTAGATGCATT
TGGTCACAAGCAGCTTGCTGGCTCAGCTAAATTCCTTGCTAACAAGATTGGTGCTGAACTTGGCATCAAGACTCGTGCTA
TCGAGCTTTCAACACTTCAGCGTTGTGCAGCTCATATGACAAGCCGTACAGATATCACAGAAGCATACAACGTTGGTGGT
GCTGCTGTTAAGGCTGCATTTGAAGGCGAGACAGGTAAGGTTGTTGTTCTTAAGAGAGTTTCTGATGATCCATATATGTG
CATCACAGAGACTAATGATGTTCACCAGATTGCTAACATCGAGAAGAAAGTTCCTCTTGAGTGGATTACAGATGATGACT
TCGTAACAGACGACCTCATCCACTACATCAGACCACTTATCCAGGCTGAGCTTTCACCAATCATGGTAGACGGTCTTCCA
AGACATCTTAATATTAATGCATAA

Upstream 100 bases:

>100_bases
ATTCAACATTTAAGTTGTATGATTATAGAAATTGTGCTAAACTATGCACATAATCACTTGCATTTTTTATGCAGAAATAT
GATTCGGAGGAGAATATAAT

Downstream 100 bases:

>100_bases
TAATAATCTTATTACATAATAAAAAGCAGGTAGGATTTTCCTCACCTGCTTTTTTGTTTCTGTCTACGCTGATATGCTCT
TACCAGTATACAACTGATAA

Product: 6-phosphofructokinase

Products: NA

Alternate protein names: 6-phosphofructokinase, pyrophosphate dependent; PPi-dependent phosphofructokinase; PPi-PFK; Pyrophosphate-dependent 6-phosphofructose-1-kinase [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MDGNVIVGQSGGPTSVINSSLAGVYKTAIDRGAKKVYGMLHGIKGLLDGQYVDLSEKINSTMDIDLLKRTPSSYLGSCRY
KLPEISEDRETFDKIFKILDDLDIKYFFYIGGNDSMDTIKKLSDYAIVTGSDIKFMGVPKTIDNDLAVTDHTPGFGSAAK
FIAATMKEIIRDGLVYDYPTVTIVEIMGRNAGWLTAAAALAKSDDCEGVDLIYLPEKVFDIDHFMARVKEIAAKGRSMVI
AVSEGIKVADGRYVFELSEHVEFVDAFGHKQLAGSAKFLANKIGAELGIKTRAIELSTLQRCAAHMTSRTDITEAYNVGG
AAVKAAFEGETGKVVVLKRVSDDPYMCITETNDVHQIANIEKKVPLEWITDDDFVTDDLIHYIRPLIQAELSPIMVDGLP
RHLNINA

Sequences:

>Translated_407_residues
MDGNVIVGQSGGPTSVINSSLAGVYKTAIDRGAKKVYGMLHGIKGLLDGQYVDLSEKINSTMDIDLLKRTPSSYLGSCRY
KLPEISEDRETFDKIFKILDDLDIKYFFYIGGNDSMDTIKKLSDYAIVTGSDIKFMGVPKTIDNDLAVTDHTPGFGSAAK
FIAATMKEIIRDGLVYDYPTVTIVEIMGRNAGWLTAAAALAKSDDCEGVDLIYLPEKVFDIDHFMARVKEIAAKGRSMVI
AVSEGIKVADGRYVFELSEHVEFVDAFGHKQLAGSAKFLANKIGAELGIKTRAIELSTLQRCAAHMTSRTDITEAYNVGG
AAVKAAFEGETGKVVVLKRVSDDPYMCITETNDVHQIANIEKKVPLEWITDDDFVTDDLIHYIRPLIQAELSPIMVDGLP
RHLNINA
>Mature_407_residues
MDGNVIVGQSGGPTSVINSSLAGVYKTAIDRGAKKVYGMLHGIKGLLDGQYVDLSEKINSTMDIDLLKRTPSSYLGSCRY
KLPEISEDRETFDKIFKILDDLDIKYFFYIGGNDSMDTIKKLSDYAIVTGSDIKFMGVPKTIDNDLAVTDHTPGFGSAAK
FIAATMKEIIRDGLVYDYPTVTIVEIMGRNAGWLTAAAALAKSDDCEGVDLIYLPEKVFDIDHFMARVKEIAAKGRSMVI
AVSEGIKVADGRYVFELSEHVEFVDAFGHKQLAGSAKFLANKIGAELGIKTRAIELSTLQRCAAHMTSRTDITEAYNVGG
AAVKAAFEGETGKVVVLKRVSDDPYMCITETNDVHQIANIEKKVPLEWITDDDFVTDDLIHYIRPLIQAELSPIMVDGLP
RHLNINA

Specific function: Key control step of glycolysis. [C]

COG id: COG0205

COG function: function code G; 6-phosphofructokinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphofructokinase family [H]

Homologues:

Organism=Escherichia coli, GI1790350, Length=360, Percent_Identity=25.5555555555556, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17558788, Length=322, Percent_Identity=24.5341614906832, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 3981 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 950 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012003
- InterPro:   IPR012829
- InterPro:   IPR022953
- InterPro:   IPR015912
- InterPro:   IPR000023 [H]

Pfam domain/function: PF00365 PFK [H]

EC number: =2.7.1.90 [H]

Molecular weight: Translated: 44610; Mature: 44610

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGNVIVGQSGGPTSVINSSLAGVYKTAIDRGAKKVYGMLHGIKGLLDGQYVDLSEKINS
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCC
TMDIDLLKRTPSSYLGSCRYKLPEISEDRETFDKIFKILDDLDIKYFFYIGGNDSMDTIK
CCCHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHH
KLSDYAIVTGSDIKFMGVPKTIDNDLAVTDHTPGFGSAAKFIAATMKEIIRDGLVYDYPT
HHHCEEEEECCCEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCEECCCC
VTIVEIMGRNAGWLTAAAALAKSDDCEGVDLIYLPEKVFDIDHFMARVKEIAAKGRSMVI
EEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEE
AVSEGIKVADGRYVFELSEHVEFVDAFGHKQLAGSAKFLANKIGAELGIKTRAIELSTLQ
EEECCCEEECCEEEEEHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHCCCEEEEEEHHHHH
RCAAHMTSRTDITEAYNVGGAAVKAAFEGETGKVVVLKRVSDDPYMCITETNDVHQIANI
HHHHHHCCCCCHHHHHCCCCHHEEEEECCCCCCEEEEEECCCCCEEEEECCCCHHHHHHH
EKKVPLEWITDDDFVTDDLIHYIRPLIQAELSPIMVDGLPRHLNINA
HHCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCEEECCC
>Mature Secondary Structure
MDGNVIVGQSGGPTSVINSSLAGVYKTAIDRGAKKVYGMLHGIKGLLDGQYVDLSEKINS
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCC
TMDIDLLKRTPSSYLGSCRYKLPEISEDRETFDKIFKILDDLDIKYFFYIGGNDSMDTIK
CCCHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHH
KLSDYAIVTGSDIKFMGVPKTIDNDLAVTDHTPGFGSAAKFIAATMKEIIRDGLVYDYPT
HHHCEEEEECCCEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCEECCCC
VTIVEIMGRNAGWLTAAAALAKSDDCEGVDLIYLPEKVFDIDHFMARVKEIAAKGRSMVI
EEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEE
AVSEGIKVADGRYVFELSEHVEFVDAFGHKQLAGSAKFLANKIGAELGIKTRAIELSTLQ
EEECCCEEECCEEEEEHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHCCCEEEEEEHHHHH
RCAAHMTSRTDITEAYNVGGAAVKAAFEGETGKVVVLKRVSDDPYMCITETNDVHQIANI
HHHHHHCCCCCHHHHHCCCCHHEEEEECCCCCCEEEEEECCCCCEEEEECCCCHHHHHHH
EKKVPLEWITDDDFVTDDLIHYIRPLIQAELSPIMVDGLPRHLNINA
HHCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10913106 [H]