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The map label for this gene is dtd

Identifier: 238916026

GI number: 238916026

Start: 62112

End: 62558

Strand: Reverse

Name: dtd

Synonym: EUBELI_00059

Alternate gene names: 238916026

Gene position: 62558-62112 (Counterclockwise)

Preceding gene: 238916031

Following gene: 238916025

Centisome position: 2.92

GC content: 43.85

Gene sequence:

>447_bases
ATGAGATTCGTAATACAACGTGTTAATCATGCAAATGTTAAGATAGATGGCGAAGTTGTTGGAAATATCGGACATGGGCT
TCTGATTCTTTTCGGGGCTGGTCAGGACGATACAGAAGAAATGCTTCCAAAATATGTAGACAAGATATGCAAAATGCGTA
TTTTTGAGGACGAGAATGGCAAAACTAATCTGTCACTGGCAGATGTCGGTGGCGAGCTGCTTATTGTAAGCCAGTTTACA
CTTTATGCGGACTGCCGCAAAGGCAACCGTCCAAGCTTTACTAATGCCGGCGCGCCTGATATGGCTAACGCCCTTTATGA
AAAATTTGTGGCAATGTGCCGTGAACGTGTTCCTAAAGTTGAAACCGGCAGATTCGGTGCTGATATGAAGGTCAGCCTTG
AAAACGACGGTCCATTCACAATACTGATAGATAGTGAGGATTTCTGA

Upstream 100 bases:

>100_bases
CAGAAGATAAAACTCATATAATAATAATGTTCCTTAACAAGTTGACACATCCCCCCTAAGCGTATAATATTCAGTTATTC
ACACATTTAAGGAGTTTAAT

Downstream 100 bases:

>100_bases
TATGTTTAGAATGTGGTGTAAGCTCTTTGACGACAGAGGGCATCTTATCAAAGACACTGTAATTAAAAATGCGGATTCTG
ATTTAAACAGAACCCGCAAA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MRFVIQRVNHANVKIDGEVVGNIGHGLLILFGAGQDDTEEMLPKYVDKICKMRIFEDENGKTNLSLADVGGELLIVSQFT
LYADCRKGNRPSFTNAGAPDMANALYEKFVAMCRERVPKVETGRFGADMKVSLENDGPFTILIDSEDF

Sequences:

>Translated_148_residues
MRFVIQRVNHANVKIDGEVVGNIGHGLLILFGAGQDDTEEMLPKYVDKICKMRIFEDENGKTNLSLADVGGELLIVSQFT
LYADCRKGNRPSFTNAGAPDMANALYEKFVAMCRERVPKVETGRFGADMKVSLENDGPFTILIDSEDF
>Mature_148_residues
MRFVIQRVNHANVKIDGEVVGNIGHGLLILFGAGQDDTEEMLPKYVDKICKMRIFEDENGKTNLSLADVGGELLIVSQFT
LYADCRKGNRPSFTNAGAPDMANALYEKFVAMCRERVPKVETGRFGADMKVSLENDGPFTILIDSEDF

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=41.2162162162162, Blast_Score=107, Evalue=3e-24,
Organism=Homo sapiens, GI18087837, Length=159, Percent_Identity=30.8176100628931, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=48.951048951049, Blast_Score=148, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI115533292, Length=150, Percent_Identity=40.6666666666667, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319982, Length=151, Percent_Identity=41.7218543046358, Blast_Score=117, Evalue=9e-28,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=42.8571428571429, Blast_Score=106, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_EUBE2 (C4Z1C2)

Other databases:

- EMBL:   CP001104
- RefSeq:   YP_002929543.1
- GeneID:   7956794
- GenomeReviews:   CP001104_GR
- KEGG:   eel:EUBELI_00059
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16422; Mature: 16422

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVIQRVNHANVKIDGEVVGNIGHGLLILFGAGQDDTEEMLPKYVDKICKMRIFEDENG
CCCEEEECCCCCEEECCEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHEEEEECCCC
KTNLSLADVGGELLIVSQFTLYADCRKGNRPSFTNAGAPDMANALYEKFVAMCRERVPKV
CCEEEEECCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
ETGRFGADMKVSLENDGPFTILIDSEDF
CCCCCCCCEEEEECCCCCEEEEEECCCC
>Mature Secondary Structure
MRFVIQRVNHANVKIDGEVVGNIGHGLLILFGAGQDDTEEMLPKYVDKICKMRIFEDENG
CCCEEEECCCCCEEECCEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHEEEEECCCC
KTNLSLADVGGELLIVSQFTLYADCRKGNRPSFTNAGAPDMANALYEKFVAMCRERVPKV
CCEEEEECCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
ETGRFGADMKVSLENDGPFTILIDSEDF
CCCCCCCCEEEEECCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA