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The map label for this gene is pgi [H]

Identifier: 238916016

GI number: 238916016

Start: 54546

End: 56126

Strand: Reverse

Name: pgi [H]

Synonym: EUBELI_00049

Alternate gene names: 238916016

Gene position: 56126-54546 (Counterclockwise)

Preceding gene: 238916017

Following gene: 238916013

Centisome position: 2.62

GC content: 41.87

Gene sequence:

>1581_bases
ATGGTTTCATGGAACAATTTAGACACACTTTCATCTTACAAGGAGTTAGCAGATGTTAAGCCAGCCTGTCTTACAGAGGT
TATGTCTGGTGATAATGGTGCAGAACGCGTTAAGAATTACAGCGTACCTATGGCTGCCGGACTTTCATATAACTACGCAT
CTAAGCAGGTTAATGAAAATGTGCTTGCTGCACTTGAAAAGCTCGCTGATGAGGCTCAGCTTGCAGACAAGTTTAAGGCT
TTATATAACGGAGAAGTTGTTAACACTGGTGAGAAGAGACTTGTTCTCCATCATATGACAAGAGGACAGTTAGGTGACGC
AGTTGAAGCTGATGGCGTTGATAAGAGAACATTTTACAAGACACAGCAGGAAAGAATTGCAGAATTTGCTAACAAGGTAC
ATAACGGTGAGATTACTAATGCAGCCGGTGAGAAGTTCACTACTGTTGTTCAGATTGGTATTGGCGGAAGCGACCTCGGT
CCTCGTGCAATGTACATAGCACTTGAGAACTGGGCTAAGAAGAACAATGCATTTAAGATGGAAGCTAAGTTCATAAGCAA
TGTTGATCCAGATGATGCTGCCGCAGTGCTTGCTTCTACTGATGTTGCACATTCTATATTCGTACTTGTTTCTAAGTCAG
GAACAACTCTTGAGACTCTTACTAATGAATCATTTGTTAAGGATGCATTAAAGAAGGCAGGACTTGATCCTTCTAAGCAC
ATGATTGCTGTAACAAGCGAGACTTCACCACTTGCCAAGAGTGATGATTATTTAGACGCATTTTTCATGGATGATTATAT
CGGAGGTCGTTTCTCTTCTACTTCATCAGTTGGCGGTGCAGTATTATCACTTGCTTTCGGACCTGAAGTATTTGCAGAAT
TCCTTGATGGTGCTGCAGAGGAGGACAAGTTATCAGCTAATCCTGATATGCGCAAGAACCCTGAGATGTTAGATGCCCTT
ATCGGTGTATACGAAAGAAATGTATTAGGTTATCCTTGTACAGCCGTTCTTCCATATTCACAGGCTTTAAGCCGTTTTCC
TGCTCATCTTCAGCAGCTTGATATGGAATCTAACGGTAAGTCAGTAAACAGATTTGGTGAGCCAGTTACTTATCCTACAG
GACCAGTTATCTTTGGTGAACCGGGAACTAACGGTCAGCATTCATTCTACCAGCTTCTTCATCAGGGAACTGACATTGTG
CCATTACAGTTCATCGGATTTAAGAACAACCAGTTAGAAACAGATGTTACAATTCAGGACAGCACAAGCCAGCAGAAGCT
TTGTGCAAATGTTGCTGCTCAGATTGTCGCATTTGCATGCGGAAAGTCAGATGAGAACCTTAACAAGAACTTCAAGGGCG
GAAGACCTTCAAGCATTATTATCGGAGACAAACTTACTCCTAAGACACTTGGTGCTTTACTTGCTCACTTCGAAAACAAG
ATTATGTTCCAGGGCTTCGTATGGAACATCAACAGCTTTGACCAGGAAGGTGTCCAGCTTGGTAAAGTACTTGCCAAGAA
GGTACTTGCTCATGATACAGATGGTGCTTTAAAGGTATATAGTGATTTACTTAATATCTAA

Upstream 100 bases:

>100_bases
TTTAATTTCTCCTTTTCCTTGAATTCGACAACCTTAAATAGTATAATTTTGTTATAATTTATTGTGTAATTAAATATTTG
TAGAGAAGGAGATATGGATT

Downstream 100 bases:

>100_bases
CGAAAAAAGGCAGGGACTTGAAATTTTCAAGTCCCTGCCTTTTTTCTAATATATTACTGTTCATTAAAAAGTGCTGTTGA
AAGATATCTGTCACCTGAAT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MVSWNNLDTLSSYKELADVKPACLTEVMSGDNGAERVKNYSVPMAAGLSYNYASKQVNENVLAALEKLADEAQLADKFKA
LYNGEVVNTGEKRLVLHHMTRGQLGDAVEADGVDKRTFYKTQQERIAEFANKVHNGEITNAAGEKFTTVVQIGIGGSDLG
PRAMYIALENWAKKNNAFKMEAKFISNVDPDDAAAVLASTDVAHSIFVLVSKSGTTLETLTNESFVKDALKKAGLDPSKH
MIAVTSETSPLAKSDDYLDAFFMDDYIGGRFSSTSSVGGAVLSLAFGPEVFAEFLDGAAEEDKLSANPDMRKNPEMLDAL
IGVYERNVLGYPCTAVLPYSQALSRFPAHLQQLDMESNGKSVNRFGEPVTYPTGPVIFGEPGTNGQHSFYQLLHQGTDIV
PLQFIGFKNNQLETDVTIQDSTSQQKLCANVAAQIVAFACGKSDENLNKNFKGGRPSSIIIGDKLTPKTLGALLAHFENK
IMFQGFVWNINSFDQEGVQLGKVLAKKVLAHDTDGALKVYSDLLNI

Sequences:

>Translated_526_residues
MVSWNNLDTLSSYKELADVKPACLTEVMSGDNGAERVKNYSVPMAAGLSYNYASKQVNENVLAALEKLADEAQLADKFKA
LYNGEVVNTGEKRLVLHHMTRGQLGDAVEADGVDKRTFYKTQQERIAEFANKVHNGEITNAAGEKFTTVVQIGIGGSDLG
PRAMYIALENWAKKNNAFKMEAKFISNVDPDDAAAVLASTDVAHSIFVLVSKSGTTLETLTNESFVKDALKKAGLDPSKH
MIAVTSETSPLAKSDDYLDAFFMDDYIGGRFSSTSSVGGAVLSLAFGPEVFAEFLDGAAEEDKLSANPDMRKNPEMLDAL
IGVYERNVLGYPCTAVLPYSQALSRFPAHLQQLDMESNGKSVNRFGEPVTYPTGPVIFGEPGTNGQHSFYQLLHQGTDIV
PLQFIGFKNNQLETDVTIQDSTSQQKLCANVAAQIVAFACGKSDENLNKNFKGGRPSSIIIGDKLTPKTLGALLAHFENK
IMFQGFVWNINSFDQEGVQLGKVLAKKVLAHDTDGALKVYSDLLNI
>Mature_526_residues
MVSWNNLDTLSSYKELADVKPACLTEVMSGDNGAERVKNYSVPMAAGLSYNYASKQVNENVLAALEKLADEAQLADKFKA
LYNGEVVNTGEKRLVLHHMTRGQLGDAVEADGVDKRTFYKTQQERIAEFANKVHNGEITNAAGEKFTTVVQIGIGGSDLG
PRAMYIALENWAKKNNAFKMEAKFISNVDPDDAAAVLASTDVAHSIFVLVSKSGTTLETLTNESFVKDALKKAGLDPSKH
MIAVTSETSPLAKSDDYLDAFFMDDYIGGRFSSTSSVGGAVLSLAFGPEVFAEFLDGAAEEDKLSANPDMRKNPEMLDAL
IGVYERNVLGYPCTAVLPYSQALSRFPAHLQQLDMESNGKSVNRFGEPVTYPTGPVIFGEPGTNGQHSFYQLLHQGTDIV
PLQFIGFKNNQLETDVTIQDSTSQQKLCANVAAQIVAFACGKSDENLNKNFKGGRPSSIIIGDKLTPKTLGALLAHFENK
IMFQGFVWNINSFDQEGVQLGKVLAKKVLAHDTDGALKVYSDLLNI

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=517, Percent_Identity=35.9767891682785, Blast_Score=300, Evalue=2e-81,
Organism=Homo sapiens, GI296080693, Length=517, Percent_Identity=34.4294003868472, Blast_Score=262, Evalue=5e-70,
Organism=Escherichia coli, GI1790457, Length=521, Percent_Identity=37.0441458733205, Blast_Score=306, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI71996703, Length=483, Percent_Identity=36.8530020703934, Blast_Score=285, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI71996708, Length=483, Percent_Identity=36.8530020703934, Blast_Score=285, Evalue=5e-77,
Organism=Saccharomyces cerevisiae, GI6319673, Length=475, Percent_Identity=38.5263157894737, Blast_Score=307, Evalue=2e-84,
Organism=Drosophila melanogaster, GI24651916, Length=502, Percent_Identity=36.2549800796813, Blast_Score=298, Evalue=6e-81,
Organism=Drosophila melanogaster, GI24651914, Length=502, Percent_Identity=36.2549800796813, Blast_Score=298, Evalue=6e-81,
Organism=Drosophila melanogaster, GI17737445, Length=502, Percent_Identity=36.2549800796813, Blast_Score=298, Evalue=6e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 57115; Mature: 57115

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSWNNLDTLSSYKELADVKPACLTEVMSGDNGAERVKNYSVPMAAGLSYNYASKQVNEN
CCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCCCCHHCCCCCCHHHHHHHHH
VLAALEKLADEAQLADKFKALYNGEVVNTGEKRLVLHHMTRGQLGDAVEADGVDKRTFYK
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCHHHHHH
TQQERIAEFANKVHNGEITNAAGEKFTTVVQIGIGGSDLGPRAMYIALENWAKKNNAFKM
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEHHHHCCCCCEEE
EAKFISNVDPDDAAAVLASTDVAHSIFVLVSKSGTTLETLTNESFVKDALKKAGLDPSKH
EHHHHCCCCCCHHHHHHHHHHHHEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCCCCCC
MIAVTSETSPLAKSDDYLDAFFMDDYIGGRFSSTSSVGGAVLSLAFGPEVFAEFLDGAAE
EEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCC
EDKLSANPDMRKNPEMLDALIGVYERNVLGYPCTAVLPYSQALSRFPAHLQQLDMESNGK
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCC
SVNRFGEPVTYPTGPVIFGEPGTNGQHSFYQLLHQGTDIVPLQFIGFKNNQLETDVTIQD
HHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEEC
STSQQKLCANVAAQIVAFACGKSDENLNKNFKGGRPSSIIIGDKLTPKTLGALLAHFENK
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCC
IMFQGFVWNINSFDQEGVQLGKVLAKKVLAHDTDGALKVYSDLLNI
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MVSWNNLDTLSSYKELADVKPACLTEVMSGDNGAERVKNYSVPMAAGLSYNYASKQVNEN
CCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCCCCHHCCCCCCHHHHHHHHH
VLAALEKLADEAQLADKFKALYNGEVVNTGEKRLVLHHMTRGQLGDAVEADGVDKRTFYK
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCHHHHHH
TQQERIAEFANKVHNGEITNAAGEKFTTVVQIGIGGSDLGPRAMYIALENWAKKNNAFKM
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEHHHHCCCCCEEE
EAKFISNVDPDDAAAVLASTDVAHSIFVLVSKSGTTLETLTNESFVKDALKKAGLDPSKH
EHHHHCCCCCCHHHHHHHHHHHHEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCCCCCC
MIAVTSETSPLAKSDDYLDAFFMDDYIGGRFSSTSSVGGAVLSLAFGPEVFAEFLDGAAE
EEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCC
EDKLSANPDMRKNPEMLDALIGVYERNVLGYPCTAVLPYSQALSRFPAHLQQLDMESNGK
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCC
SVNRFGEPVTYPTGPVIFGEPGTNGQHSFYQLLHQGTDIVPLQFIGFKNNQLETDVTIQD
HHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEEC
STSQQKLCANVAAQIVAFACGKSDENLNKNFKGGRPSSIIIGDKLTPKTLGALLAHFENK
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCC
IMFQGFVWNINSFDQEGVQLGKVLAKKVLAHDTDGALKVYSDLLNI
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA