Click here to switch to the map view.

The map label for this gene is proA [H]

Identifier: 238897153

GI number: 238897153

Start: 5153451

End: 5154164

Strand: Reverse

Name: proA [H]

Synonym: KP1_5417

Alternate gene names: 238897153

Gene position: 5154164-5153451 (Counterclockwise)

Preceding gene: 238897154

Following gene: 238897152

Centisome position: 98.2

GC content: 62.46

Gene sequence:

>714_bases
ATGAACCTGTTAAATAAAAAAGGCCTTGTGATCCGCCACCTGCCGCGCCATGACGAGGCGGTTTTGCGCCGCTGTGAGGC
GGCCGGGGTGGCGACGCTCCATGAAGCCTGGGATCGTCAGGGGCTGATGGGGCCGGCAATCCGTCCGATTCAGCAGGGCG
TCAGCCGGGCGGGCAACGCGGTAACCGTGCTGGTGACGCCTGGCGACAACTGGATGTTTCATGTCGCGGTCGAGCAGTGC
CGCGCCGGCGATATTCTGGTGGTGGCCCCGACCTCGCCGTGCGGCGATGGCTTCTTCGGCGATCTACTGGCGACGTCTCT
CCAATCGCGCGGCGTGGTCGGGCTGGTGGGCGATATCGGCATTCGTGATTCGCAAACGTTGCGGGAAATGGGATTCGCCG
TCTGGTCCCGTCAGGTTTATGCCCAGGGGACGGTGAAAGAGAGCCTCGGTTCGGTTAACGTCCCGGTGATATGCGCAGGT
CAGCTTGTACAGCCGGGCGATGTCGTAGTGGCCGACGACGATGGCGTCGTGGTGCTGCCTCACGCCCGGGTCCGTGATGT
GCTCCATAAAGCGGAAGCCCGCATGAGCAATGAGCTTGCGAAACGTGAGCGGATGCGCAATGGCGAGTTGGGGCTGGATA
TTTACGCTATGCGTCCGCGTCTGGCGGAAAAGGGCCTGCGGTATTACGACCGCGCAGACGAGGTGGAGGAATAA

Upstream 100 bases:

>100_bases
GGGTGCAGGCCAAGCGCAATATCGGCATCACGGCCGCGCGCGATATCGTTCACGGCGAAGCCTTCCAGAGCATCTTCCCC
CGCGTAACGGAGAACCTGGC

Downstream 100 bases:

>100_bases
ATGGCGCAACGCGGAATCCCCTGTCTATGGATGCGCGGCGGCACCTCTAAAGCGGCCTGTTTTCTGGCCGACGATCTGCC
TGCCGATCCGGTGCGACGTG

Product: hypothetical protein

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MNLLNKKGLVIRHLPRHDEAVLRRCEAAGVATLHEAWDRQGLMGPAIRPIQQGVSRAGNAVTVLVTPGDNWMFHVAVEQC
RAGDILVVAPTSPCGDGFFGDLLATSLQSRGVVGLVGDIGIRDSQTLREMGFAVWSRQVYAQGTVKESLGSVNVPVICAG
QLVQPGDVVVADDDGVVVLPHARVRDVLHKAEARMSNELAKRERMRNGELGLDIYAMRPRLAEKGLRYYDRADEVEE

Sequences:

>Translated_237_residues
MNLLNKKGLVIRHLPRHDEAVLRRCEAAGVATLHEAWDRQGLMGPAIRPIQQGVSRAGNAVTVLVTPGDNWMFHVAVEQC
RAGDILVVAPTSPCGDGFFGDLLATSLQSRGVVGLVGDIGIRDSQTLREMGFAVWSRQVYAQGTVKESLGSVNVPVICAG
QLVQPGDVVVADDDGVVVLPHARVRDVLHKAEARMSNELAKRERMRNGELGLDIYAMRPRLAEKGLRYYDRADEVEE
>Mature_237_residues
MNLLNKKGLVIRHLPRHDEAVLRRCEAAGVATLHEAWDRQGLMGPAIRPIQQGVSRAGNAVTVLVTPGDNWMFHVAVEQC
RAGDILVVAPTSPCGDGFFGDLLATSLQSRGVVGLVGDIGIRDSQTLREMGFAVWSRQVYAQGTVKESLGSVNVPVICAG
QLVQPGDVVVADDDGVVVLPHARVRDVLHKAEARMSNELAKRERMRNGELGLDIYAMRPRLAEKGLRYYDRADEVEE

Specific function: Plays a role in protocatechuate degradation. Has a broad substrate specificity and catalyzes the aldol cleavage of 4- hydroxy-4-methyl-2-oxoglutarate, 4-hydroxy-2-oxoglutarate and 4- carboxy-4-hydroxy-2-oxoadipate, and the decarboxylation of oxaloacetate.

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014165
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6 [H]

EC number: =4.1.1.3; =4.1.3.16; =4.1.3.17 [H]

Molecular weight: Translated: 25855; Mature: 25855

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLNKKGLVIRHLPRHDEAVLRRCEAAGVATLHEAWDRQGLMGPAIRPIQQGVSRAGNA
CCCCCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCE
VTVLVTPGDNWMFHVAVEQCRAGDILVVAPTSPCGDGFFGDLLATSLQSRGVVGLVGDIG
EEEEEECCCCEEEEEEEHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCC
IRDSQTLREMGFAVWSRQVYAQGTVKESLGSVNVPVICAGQLVQPGDVVVADDDGVVVLP
CCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEECCCEECCCCEEEECCCCEEEEC
HARVRDVLHKAEARMSNELAKRERMRNGELGLDIYAMRPRLAEKGLRYYDRADEVEE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNLLNKKGLVIRHLPRHDEAVLRRCEAAGVATLHEAWDRQGLMGPAIRPIQQGVSRAGNA
CCCCCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCE
VTVLVTPGDNWMFHVAVEQCRAGDILVVAPTSPCGDGFFGDLLATSLQSRGVVGLVGDIG
EEEEEECCCCEEEEEEEHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCC
IRDSQTLREMGFAVWSRQVYAQGTVKESLGSVNVPVICAGQLVQPGDVVVADDDGVVVLP
CCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEECCCEECCCCEEEECCCCEEEEC
HARVRDVLHKAEARMSNELAKRERMRNGELGLDIYAMRPRLAEKGLRYYDRADEVEE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11826967 [H]