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The map label for this gene is lldR [H]

Identifier: 238897048

GI number: 238897048

Start: 5044844

End: 5045608

Strand: Direct

Name: lldR [H]

Synonym: KP1_5297

Alternate gene names: 238897048

Gene position: 5044844-5045608 (Clockwise)

Preceding gene: 238897047

Following gene: 238897049

Centisome position: 96.12

GC content: 63.27

Gene sequence:

>765_bases
ATGCCTAAACGCCTGGCCGACGACGTGGCGCGTCGCGTCCGGGCGCTGATTGAAGAACAACAGCTGGAGGCGGGCATGCG
ACTGCCCGCCGAGCGCCAGCTCGCCGCCCAGCTCGGCGTCTCACGCAATTCCCTGCGCGAAGCGCTGGCGATGCTGGTCA
ATGAAGGGGTGCTGTTGAGCCGTCGCGGCGGCGGCACCTTCGTCCGCTTTCAGCATGAGCCGTGGTCAGAGCAAAACATC
GTCCAGCCGCTGAAGACGCTGCTGGCCGATGACCCCGACTACAGCTTCGATATCCTCGAAGCTCGCCACGCCATCGAAGC
CAGCACCGCGTGGCACGCGGCGATGCGCGCCACCGACGCCGATAAAGAAAAAATTCGTCTGTGCTTTGAAGCGACCCAGA
GTGAAGACCCGGATATCGCCTCGCAGGCGGATGTCCGCTTTCACCTGGCGATCGCCGAAGCCTCGCATAACGTGGTGCTC
CTGCAAACCATGCGCGGCTTTTTCGACCTGCTGCACTCCTCCGTTAAGCAGAGCCGCCAGCGCATGTATCAGGTGCCGCC
GGTGTTTGCCCGCCTGACCGAACAGCACCAGGCCGTCATGGAGGCGATTGTCGCCGGCGACGCCGAGGCGGCGCGCCAGG
CGATGATGGGCCACTTAGGCTTTGTCCACGCCACCATCAAACGTTTTGATGAAGACCAGGCCCGCCAGGCGCGAATTACC
CGCCTGCCCGGTGACCACAATGAAAATTCCAGGGAGAACTCGTGA

Upstream 100 bases:

>100_bases
TCCGCTTTACCGTCAAACACAGCCTGATCTTCACCTGCATGGTGGGGCTGATCACCACGCTGCAGGCCTACGTTTTAACC
TGGATGATCCCGTGATAGTG

Downstream 100 bases:

>100_bases
TGATTATTTCCGCCGCCAGCGACTATCGCGCCGCCGCACAGCGTATCCTGCCGCCGTTTCTGTTCCACTATATTGACGGC
GGCGCCTACGCCGAGCATAC

Product: DNA-binding transcriptional repressor LldR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MPKRLADDVARRVRALIEEQQLEAGMRLPAERQLAAQLGVSRNSLREALAMLVNEGVLLSRRGGGTFVRFQHEPWSEQNI
VQPLKTLLADDPDYSFDILEARHAIEASTAWHAAMRATDADKEKIRLCFEATQSEDPDIASQADVRFHLAIAEASHNVVL
LQTMRGFFDLLHSSVKQSRQRMYQVPPVFARLTEQHQAVMEAIVAGDAEAARQAMMGHLGFVHATIKRFDEDQARQARIT
RLPGDHNENSRENS

Sequences:

>Translated_254_residues
MPKRLADDVARRVRALIEEQQLEAGMRLPAERQLAAQLGVSRNSLREALAMLVNEGVLLSRRGGGTFVRFQHEPWSEQNI
VQPLKTLLADDPDYSFDILEARHAIEASTAWHAAMRATDADKEKIRLCFEATQSEDPDIASQADVRFHLAIAEASHNVVL
LQTMRGFFDLLHSSVKQSRQRMYQVPPVFARLTEQHQAVMEAIVAGDAEAARQAMMGHLGFVHATIKRFDEDQARQARIT
RLPGDHNENSRENS
>Mature_253_residues
PKRLADDVARRVRALIEEQQLEAGMRLPAERQLAAQLGVSRNSLREALAMLVNEGVLLSRRGGGTFVRFQHEPWSEQNIV
QPLKTLLADDPDYSFDILEARHAIEASTAWHAAMRATDADKEKIRLCFEATQSEDPDIASQADVRFHLAIAEASHNVVLL
QTMRGFFDLLHSSVKQSRQRMYQVPPVFARLTEQHQAVMEAIVAGDAEAARQAMMGHLGFVHATIKRFDEDQARQARITR
LPGDHNENSRENS

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=254, Percent_Identity=82.2834645669291, Blast_Score=438, Evalue=1e-124,
Organism=Escherichia coli, GI1786303, Length=223, Percent_Identity=41.7040358744395, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1790780, Length=243, Percent_Identity=32.9218106995885, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789353, Length=228, Percent_Identity=32.0175438596491, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082208, Length=232, Percent_Identity=29.7413793103448, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 28599; Mature: 28468

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKRLADDVARRVRALIEEQQLEAGMRLPAERQLAAQLGVSRNSLREALAMLVNEGVLLS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEE
RRGGGTFVRFQHEPWSEQNIVQPLKTLLADDPDYSFDILEARHAIEASTAWHAAMRATDA
ECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DKEKIRLCFEATQSEDPDIASQADVRFHLAIAEASHNVVLLQTMRGFFDLLHSSVKQSRQ
CHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHH
RMYQVPPVFARLTEQHQAVMEAIVAGDAEAARQAMMGHLGFVHATIKRFDEDQARQARIT
HHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
RLPGDHNENSRENS
CCCCCCCCCCCCCC
>Mature Secondary Structure 
PKRLADDVARRVRALIEEQQLEAGMRLPAERQLAAQLGVSRNSLREALAMLVNEGVLLS
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEE
RRGGGTFVRFQHEPWSEQNIVQPLKTLLADDPDYSFDILEARHAIEASTAWHAAMRATDA
ECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DKEKIRLCFEATQSEDPDIASQADVRFHLAIAEASHNVVLLQTMRGFFDLLHSSVKQSRQ
CHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHH
RMYQVPPVFARLTEQHQAVMEAIVAGDAEAARQAMMGHLGFVHATIKRFDEDQARQARIT
HHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
RLPGDHNENSRENS
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]