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The map label for this gene is ttuB [H]

Identifier: 238897014

GI number: 238897014

Start: 5005412

End: 5006692

Strand: Direct

Name: ttuB [H]

Synonym: KP1_5260

Alternate gene names: 238897014

Gene position: 5005412-5006692 (Clockwise)

Preceding gene: 238897013

Following gene: 238897015

Centisome position: 95.37

GC content: 58.86

Gene sequence:

>1281_bases
ATGAATAGCTCAACAAATGCAACGAAACGCTGGTGGTACATCATGCCTATCGTGTTTATCACGTATAGCCTGGCGTACCT
CGACCGCGCCAACTTCAGCTTCGCCTCCGCGGCAGGCATTACCGAAGACCTGGGCATCACCAAGGGGATCTCCTCCCTGC
TGGGGGCGCTGTTCTTCCTCGGCTACTTCTTCTTCCAGATCCCCGGCGCTATCTATGCGGAGCGCCGCAGCGTTCGCAAA
CTGATCTTTATCTGCCTGATCCTGTGGGGCGGTTGCGCCTCCCTGACCGGTATTGTGCATAATATCCCGGCGCTGGCGGC
GATCCGCTTTATCCTCGGCGTCGTCGAAGCCGCGGTGATGCCGGCGATGCTTATCTATATCAGCAACTGGTTCACCAAAT
CAGAGCGCTCTCGCGCCAACACCTTCCTGATCCTCGGTAACCCGGTGACGGTCCTGTGGATGTCGGTAGTCTCCGGCTAC
CTGATTCAGGCCTTCGGCTGGCGGGAAATGTTCATCATCGAAGGGGTGCCGGCGGTGATCTGGGCCTTCTGCTGGTGGGT
GCTAGTGAAAGATAAGCCGTCGCAGGTGTCCTGGCTGGCGGAGAGTGAAAAAGCGGCGCTGCAGGAACAACTGGATCGTG
AACAGCAAGGCATCAAAGCGGTGCGTAACTATGGCGAAGCCTTCCGCTCCCGCAACGTGATCCTGCTCTGCGCGCAGTAT
TTTGCCTGGAGTATCGGCGTATACGGCTTTGTACTGTGGCTGCCGTCGATTATCCGCAGCGGCGGTGAAAATATGGGGAT
GGTGGAAGTGGGCTGGCTCTCTTCTGTCCCGTACCTGGCGGCCACCATCGCCATGATCGTCGTCTCCTGGGCCTCGGATA
AACTGCAAAACCGTAAGCTGTTCGTCTGGCCGCTGCTGCTGATTGGCGGACTGGCCTTCATCGGTTCCTGGGCGGTCGGC
GCCAACCACTTCTGGGTCTCCTACACCCTGCTGGTGGTGGCCGGGGCGGCAATGTATGCGCCTTACGGCCCCTTCTTCGC
CATTATTCCGGAAATGCTGCCGCGCAACGTCGCCGGGGGCGCCATGGCGCTGATCAACAGCATGGGCGCGCTGGGCTCCT
TCTGCGGCTCGTGGTTTGTCGGCTACCTGAACGGCGCCACCGGCAGCCCCGCAGCGTCCTATATTTTTATGGGGGTAGCG
CTTTTCGCCTCAGTATGGCTGACTTTGATTGTTAAGCCTGCTAATAATCAAAACCTTCCACTTGGCGCTCATCACGCCTG
A

Upstream 100 bases:

>100_bases
TCTACGCAACGATAACAGCCGTCCTGTACCCTACCTGCAGCGCGGCACAGCAGCGTCCGTTTCGACGGACGTATGTCTCC
TCATTGACAGAGGCAAGCCT

Downstream 100 bases:

>100_bases
ACGACTCATACTACGGAGATTCGCATGAAGCCGTCTGTCATTCTCTATAAAACGCTTCCCGACGACCTGCTACAGCGTCT
GGAGGAGCACTTTTCCGTCA

Product: general substrate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MNSSTNATKRWWYIMPIVFITYSLAYLDRANFSFASAAGITEDLGITKGISSLLGALFFLGYFFFQIPGAIYAERRSVRK
LIFICLILWGGCASLTGIVHNIPALAAIRFILGVVEAAVMPAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGY
LIQAFGWREMFIIEGVPAVIWAFCWWVLVKDKPSQVSWLAESEKAALQEQLDREQQGIKAVRNYGEAFRSRNVILLCAQY
FAWSIGVYGFVLWLPSIIRSGGENMGMVEVGWLSSVPYLAATIAMIVVSWASDKLQNRKLFVWPLLLIGGLAFIGSWAVG
ANHFWVSYTLLVVAGAAMYAPYGPFFAIIPEMLPRNVAGGAMALINSMGALGSFCGSWFVGYLNGATGSPAASYIFMGVA
LFASVWLTLIVKPANNQNLPLGAHHA

Sequences:

>Translated_426_residues
MNSSTNATKRWWYIMPIVFITYSLAYLDRANFSFASAAGITEDLGITKGISSLLGALFFLGYFFFQIPGAIYAERRSVRK
LIFICLILWGGCASLTGIVHNIPALAAIRFILGVVEAAVMPAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGY
LIQAFGWREMFIIEGVPAVIWAFCWWVLVKDKPSQVSWLAESEKAALQEQLDREQQGIKAVRNYGEAFRSRNVILLCAQY
FAWSIGVYGFVLWLPSIIRSGGENMGMVEVGWLSSVPYLAATIAMIVVSWASDKLQNRKLFVWPLLLIGGLAFIGSWAVG
ANHFWVSYTLLVVAGAAMYAPYGPFFAIIPEMLPRNVAGGAMALINSMGALGSFCGSWFVGYLNGATGSPAASYIFMGVA
LFASVWLTLIVKPANNQNLPLGAHHA
>Mature_426_residues
MNSSTNATKRWWYIMPIVFITYSLAYLDRANFSFASAAGITEDLGITKGISSLLGALFFLGYFFFQIPGAIYAERRSVRK
LIFICLILWGGCASLTGIVHNIPALAAIRFILGVVEAAVMPAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGY
LIQAFGWREMFIIEGVPAVIWAFCWWVLVKDKPSQVSWLAESEKAALQEQLDREQQGIKAVRNYGEAFRSRNVILLCAQY
FAWSIGVYGFVLWLPSIIRSGGENMGMVEVGWLSSVPYLAATIAMIVVSWASDKLQNRKLFVWPLLLIGGLAFIGSWAVG
ANHFWVSYTLLVVAGAAMYAPYGPFFAIIPEMLPRNVAGGAMALINSMGALGSFCGSWFVGYLNGATGSPAASYIFMGVA
LFASVWLTLIVKPANNQNLPLGAHHA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=381, Percent_Identity=23.3595800524934, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI9966811, Length=366, Percent_Identity=24.3169398907104, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87082071, Length=371, Percent_Identity=26.4150943396226, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI87082320, Length=432, Percent_Identity=25.2314814814815, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI2367379, Length=293, Percent_Identity=23.2081911262799, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789515, Length=445, Percent_Identity=24.4943820224719, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789152, Length=434, Percent_Identity=23.0414746543779, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI2367193, Length=436, Percent_Identity=25, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082404, Length=377, Percent_Identity=24.4031830238727, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI115533556, Length=253, Percent_Identity=26.4822134387352, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI86561091, Length=252, Percent_Identity=25.7936507936508, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25141318, Length=252, Percent_Identity=25.7936507936508, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533554, Length=272, Percent_Identity=27.2058823529412, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25141316, Length=252, Percent_Identity=25.7936507936508, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25141341, Length=201, Percent_Identity=27.363184079602, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17535049, Length=423, Percent_Identity=24.822695035461, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17552542, Length=326, Percent_Identity=24.2331288343558, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32565916, Length=197, Percent_Identity=24.8730964467005, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32565914, Length=197, Percent_Identity=24.8730964467005, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322612, Length=220, Percent_Identity=24.0909090909091, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322973, Length=130, Percent_Identity=29.2307692307692, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6321698, Length=342, Percent_Identity=23.6842105263158, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI45550460, Length=410, Percent_Identity=23.9024390243902, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24580790, Length=378, Percent_Identity=23.8095238095238, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24655255, Length=371, Percent_Identity=24.2587601078167, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648416, Length=277, Percent_Identity=27.0758122743682, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356189, Length=277, Percent_Identity=27.0758122743682, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573708, Length=332, Percent_Identity=24.3975903614458, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573707, Length=332, Percent_Identity=24.3975903614458, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20130135, Length=453, Percent_Identity=22.7373068432671, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24655271, Length=453, Percent_Identity=22.7373068432671, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24583789, Length=423, Percent_Identity=22.4586288416076, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573299, Length=294, Percent_Identity=22.4489795918367, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46838; Mature: 46838

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSTNATKRWWYIMPIVFITYSLAYLDRANFSFASAAGITEDLGITKGISSLLGALFFL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHH
GYFFFQIPGAIYAERRSVRKLIFICLILWGGCASLTGIVHNIPALAAIRFILGVVEAAVM
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGYLIQAFGWREMFIIEGVPAVI
HHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHH
WAFCWWVLVKDKPSQVSWLAESEKAALQEQLDREQQGIKAVRNYGEAFRSRNVILLCAQY
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHH
FAWSIGVYGFVLWLPSIIRSGGENMGMVEVGWLSSVPYLAATIAMIVVSWASDKLQNRKL
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
FVWPLLLIGGLAFIGSWAVGANHFWVSYTLLVVAGAAMYAPYGPFFAIIPEMLPRNVAGG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCH
AMALINSMGALGSFCGSWFVGYLNGATGSPAASYIFMGVALFASVWLTLIVKPANNQNLP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCC
LGAHHA
CCCCCC
>Mature Secondary Structure
MNSSTNATKRWWYIMPIVFITYSLAYLDRANFSFASAAGITEDLGITKGISSLLGALFFL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHH
GYFFFQIPGAIYAERRSVRKLIFICLILWGGCASLTGIVHNIPALAAIRFILGVVEAAVM
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSVVSGYLIQAFGWREMFIIEGVPAVI
HHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHH
WAFCWWVLVKDKPSQVSWLAESEKAALQEQLDREQQGIKAVRNYGEAFRSRNVILLCAQY
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHH
FAWSIGVYGFVLWLPSIIRSGGENMGMVEVGWLSSVPYLAATIAMIVVSWASDKLQNRKL
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
FVWPLLLIGGLAFIGSWAVGANHFWVSYTLLVVAGAAMYAPYGPFFAIIPEMLPRNVAGG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCH
AMALINSMGALGSFCGSWFVGYLNGATGSPAASYIFMGVALFASVWLTLIVKPANNQNLP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCC
LGAHHA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]