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The map label for this gene is rpe [H]

Identifier: 238896854

GI number: 238896854

Start: 4818077

End: 4818754

Strand: Reverse

Name: rpe [H]

Synonym: KP1_5087

Alternate gene names: 238896854

Gene position: 4818754-4818077 (Counterclockwise)

Preceding gene: 238896855

Following gene: 238896853

Centisome position: 91.81

GC content: 56.34

Gene sequence:

>678_bases
ATGAAGCAGTATTTGATTGCCCCTTCGATTCTGTCGGCTGATTTTGCCCGTCTGGGTGAGGATACCGCGAAGGCGCTGGC
GGCGGGTGCGGATGTCGTGCACTTCGACGTTATGGACAACCACTACGTGCCAAACCTGACGATTGGCCCGATGGTGCTGA
AGTCACTGCGTAATTACGGTATTACCGCGCCAATCGACGTTCACCTGATGGTGAAGCCGGTCGACCGCATCATTCCTGAT
TTTGCCGAAGCCGGCGCCAGCATTATCACCTTCCATCCGGAAGCCTCCGAACACGTCGATCGCAGCCTGCAGCTTATCAA
AGAGCACGGCTGTAAAGCGGGCCTGGTGTTTAACCCGGCGACGCCGCTGAGCTACCTCGATTACGTGATGGATAAGCTGG
ACGTGATCCTGCTGATGTCGGTTAACCCGGGCTTTGGCGGCCAGTCCTTTATTCCCCAGACGCTGGATAAACTGCGTGAA
GTGCGCCAGCGCATCGATGCGTCCGGCTACGACATCCGCCTGGAAGTGGATGGCGGCGTGAAAGCCAGCAATATCGGCGA
AATCGCCGCGGCGGGTGCGGATATGTTTGTTGCCGGTTCGGCGATCTTCGGTCAGCCGGACTACAAGCAAGTCATTGATC
AAATGCGTAGTGAATTAGCGAAGGTGAGTCATGGATAA

Upstream 100 bases:

>100_bases
GGCGCAGCATCAGCAGCAACGGTGGTACGCGTAAAAAGGTGGACGAGCTATTAGCGCTCTACCGTCCGCCTAAGACCAAA
TAAATTTCAAGGAGATGCGG

Downstream 100 bases:

>100_bases
ATTACAGGCGATCCGCGGCATCGCATTTGATCTCGACGGCACGCTGGTGGACAGCGCGCCGGGTCTAACCTCGGCGGTTG
ATAACGCCCTGTACGCCCTG

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRNYGITAPIDVHLMVKPVDRIIPD
FAEAGASIITFHPEASEHVDRSLQLIKEHGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
VRQRIDASGYDIRLEVDGGVKASNIGEIAAAGADMFVAGSAIFGQPDYKQVIDQMRSELAKVSHG

Sequences:

>Translated_225_residues
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRNYGITAPIDVHLMVKPVDRIIPD
FAEAGASIITFHPEASEHVDRSLQLIKEHGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
VRQRIDASGYDIRLEVDGGVKASNIGEIAAAGADMFVAGSAIFGQPDYKQVIDQMRSELAKVSHG
>Mature_225_residues
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRNYGITAPIDVHLMVKPVDRIIPD
FAEAGASIITFHPEASEHVDRSLQLIKEHGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
VRQRIDASGYDIRLEVDGGVKASNIGEIAAAGADMFVAGSAIFGQPDYKQVIDQMRSELAKVSHG

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=220, Percent_Identity=39.0909090909091, Blast_Score=158, Evalue=3e-39,
Organism=Homo sapiens, GI219879828, Length=213, Percent_Identity=38.9671361502347, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI24307923, Length=176, Percent_Identity=31.8181818181818, Blast_Score=95, Evalue=6e-20,
Organism=Escherichia coli, GI1789788, Length=224, Percent_Identity=94.6428571428571, Blast_Score=436, Evalue=1e-124,
Organism=Escherichia coli, GI1790523, Length=210, Percent_Identity=37.6190476190476, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1790754, Length=211, Percent_Identity=28.9099526066351, Blast_Score=94, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17552948, Length=217, Percent_Identity=40.0921658986175, Blast_Score=151, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6322341, Length=233, Percent_Identity=38.1974248927039, Blast_Score=158, Evalue=8e-40,
Organism=Drosophila melanogaster, GI24586301, Length=214, Percent_Identity=41.588785046729, Blast_Score=164, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24379; Mature: 24379

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRNYG
CCCEECCHHHHHHHHHHHCHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
ITAPIDVHLMVKPVDRIIPDFAEAGASIITFHPEASEHVDRSLQLIKEHGCKAGLVFNPA
CCCCEEEEEEECCHHHHCHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCC
TPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLREVRQRIDASGYDIRLEVDGGV
CHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCC
KASNIGEIAAAGADMFVAGSAIFGQPDYKQVIDQMRSELAKVSHG
CCCCCCHHHHCCCCCEEECCHHCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRNYG
CCCEECCHHHHHHHHHHHCHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
ITAPIDVHLMVKPVDRIIPDFAEAGASIITFHPEASEHVDRSLQLIKEHGCKAGLVFNPA
CCCCEEEEEEECCHHHHCHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCC
TPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLREVRQRIDASGYDIRLEVDGGV
CHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCC
KASNIGEIAAAGADMFVAGSAIFGQPDYKQVIDQMRSELAKVSHG
CCCCCCHHHHCCCCCEEECCHHCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]