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The map label for this gene is prmA [H]

Identifier: 238896766

GI number: 238896766

Start: 4746290

End: 4747171

Strand: Direct

Name: prmA [H]

Synonym: KP1_4986

Alternate gene names: 238896766

Gene position: 4746290-4747171 (Clockwise)

Preceding gene: 238896765

Following gene: 238896767

Centisome position: 90.43

GC content: 58.84

Gene sequence:

>882_bases
ATGCCATGGATCCAACTGAAACTAAATACCACCGGCGCGAACGCTGAAGATCTTAGCGATGCGCTGATGGAGGCCGGATC
GGTCTCGATCACCTTCCAGGATACGCACGATACGCCGGTATTTGAGCCATTGCCCGGGGAAACCCGCCTGTGGGGGGATA
CCGACGTAATCGGCCTGTTCGATGCTGAAACCGATATGAAAGCGGTCGTTGCCCAACTGGAGCAGCATCCGCTGCTGGGC
GCCGGGTTCGCGCATAAGATCGAGCAGCTGGAAGATAAAGACTGGGAACGGGAATGGATGGATAACTTCCACCCCATGCG
CTTCGGGGAGCGGCTATGGATCTGCCCAAGCTGGCGCGATGTTCCGGATGAAAATGCCGTCAACGTGATGCTCGATCCGG
GTCTGGCCTTTGGCACCGGTACGCATCCGACGACATCCCTGTGCCTGCAGTGGCTGGATGGACTCGACCTCAACGGAAAA
ACGGTGATTGATTTCGGCTGCGGCTCCGGCATCCTGGCGATTGCCGCACTGAAGCTGGGGGCGGCAAAAGCAATCGGGAT
TGATATCGACCCGCAGGCTATTCAGGCCAGTCGTGATAACGCGCAGCGTAACGGCGTTTCTGAACGCCTGGAGCTCTATC
TTCCTCAGGACCAACCGGAGTCGATGAAAGCCGACGTGGTGGTCGCGAATATCCTGGCAGGCCCGCTGCGTGAGCTGGCG
CCATTAATCAGCGTCCTGCCCGTTTCAGGCGGTTTGCTGGGGCTTTCCGGCATCCTTGCCAGCCAGGCGGAGAGCGTCTG
TGAAGCCTACGCCGATCTCTTCACCCTTGACCCGGTGGTCGAGAAGGAAGAGTGGTGCCGGATTACCGGCCGGAAAAACT
AA

Upstream 100 bases:

>100_bases
CGCTGCTGCTGAGTTTGCTGGCGTTTGTGGCGGGGAACCGTTTCGGTCGTCCCGCCCCACAGTCCCCCATTTTGACTACT
GATAAATAAAGAGTTTTGCT

Downstream 100 bases:

>100_bases
GCGCGATGCGGCCTACGGGCCGCATTTTTGTTTCCAGTAGCCACCAAATAATGCCAGGAAATGAGAGGCAGATCGCACTA
CAGAGCACTTTTTTGGCTAC

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MPWIQLKLNTTGANAEDLSDALMEAGSVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMKAVVAQLEQHPLLG
AGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDGLDLNGK
TVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAQRNGVSERLELYLPQDQPESMKADVVVANILAGPLRELA
PLISVLPVSGGLLGLSGILASQAESVCEAYADLFTLDPVVEKEEWCRITGRKN

Sequences:

>Translated_293_residues
MPWIQLKLNTTGANAEDLSDALMEAGSVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMKAVVAQLEQHPLLG
AGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDGLDLNGK
TVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAQRNGVSERLELYLPQDQPESMKADVVVANILAGPLRELA
PLISVLPVSGGLLGLSGILASQAESVCEAYADLFTLDPVVEKEEWCRITGRKN
>Mature_292_residues
PWIQLKLNTTGANAEDLSDALMEAGSVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMKAVVAQLEQHPLLGA
GFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDGLDLNGKT
VIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAQRNGVSERLELYLPQDQPESMKADVVVANILAGPLRELAP
LISVLPVSGGLLGLSGILASQAESVCEAYADLFTLDPVVEKEEWCRITGRKN

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=293, Percent_Identity=95.5631399317406, Blast_Score=527, Evalue=1e-151,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31902; Mature: 31771

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWIQLKLNTTGANAEDLSDALMEAGSVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLF
CCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCEEEEE
DAETDMKAVVAQLEQHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRD
ECCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEECCCCCC
VPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDGLDLNGKTVIDFGCGSGILAIAALKLG
CCCCCCEEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHC
AAKAIGIDIDPQAIQASRDNAQRNGVSERLELYLPQDQPESMKADVVVANILAGPLRELA
CCEEEECCCCHHHHHHHHHHHHHCCHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
PLISVLPVSGGLLGLSGILASQAESVCEAYADLFTLDPVVEKEEWCRITGRKN
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHCCCCCCC
>Mature Secondary Structure 
PWIQLKLNTTGANAEDLSDALMEAGSVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLF
CEEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCEEEEE
DAETDMKAVVAQLEQHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRD
ECCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEECCCCCC
VPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDGLDLNGKTVIDFGCGSGILAIAALKLG
CCCCCCEEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHC
AAKAIGIDIDPQAIQASRDNAQRNGVSERLELYLPQDQPESMKADVVVANILAGPLRELA
CCEEEECCCCHHHHHHHHHHHHHCCHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
PLISVLPVSGGLLGLSGILASQAESVCEAYADLFTLDPVVEKEEWCRITGRKN
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA