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The map label for this gene is mreB [H]

Identifier: 238896756

GI number: 238896756

Start: 4736560

End: 4737678

Strand: Reverse

Name: mreB [H]

Synonym: KP1_4975

Alternate gene names: 238896756

Gene position: 4737678-4736560 (Counterclockwise)

Preceding gene: 238896757

Following gene: 238896755

Centisome position: 90.27

GC content: 57.1

Gene sequence:

>1119_bases
TTGTCGCTGCTGCGTGTGGTTGGTAAAGTAAGCGGATTTTGTTTTCCGCCCCAGCTTTCAGGATTATCCCTTAGTATGTT
AAAAAAATTTCGTGGCATGTTTTCCAATGACCTGTCCATTGACCTGGGTACCGCGAATACCCTTATTTACGTAAAAGGAC
AAGGCATCGTATTGAATGAGCCTTCCGTGGTGGCCATTCGTCAGGATCGTGCCGGATCGCCGAAAAGCGTCGCCGCCGTG
GGTCATGAAGCGAAGCAGATGCTCGGCCGTACCCCGGGTAATATCGCGGCGATTCGCCCGATGAAGGACGGCGTTATCGC
TGACTTCTTCGTGACGGAAAAGATGCTGCAGCACTTTATCAAACAAGTGCACAGCAACAGCTTTATGCGCCCGAGCCCGC
GCGTGCTGGTGTGTGTACCGGTTGGCGCAACCCAGGTCGAACGTCGCGCTATTCGTGAATCCGCGCAGGGCGCAGGCGCC
CGTGAAGTCTTCCTGATCGAAGAGCCGATGGCGGCAGCGATTGGCGCAGGCTTACCGGTTTCTGAAGCGACCGGCTCCAT
GGTGGTGGATATCGGTGGCGGTACCACTGAGGTGGCGGTTATCTCCCTGAACGGCGTAGTCTATTCCTCTTCTGTACGTA
TCGGCGGTGACCGCTTCGACGAAGCCGTTATCAATTACGTGCGTCGTAACTACGGCTCCCTGATCGGTGAAGCGACCGCT
GAACGTATCAAGCATGAAATCGGTTCGGCTTACCCGGGCGATGAAGTGCGCGAAATTGAAGTGCGCGGTCGTAACCTGGC
GGAAGGCGTGCCACGCGGCTTCACCCTGAACTCAAACGAAATTCTTGAAGCGCTGCAGGAGCCTCTGACCGGCATCGTGA
GCGCGGTCATGGTTGCCCTTGAGCAGTGCCCGCCGGAACTGGCGTCTGATATCTCTGAACGCGGGATGGTTCTCACCGGC
GGTGGTGCGCTGCTGCGCAACCTGGACCGTCTGTTAATGGAAGAAACCGGTATTCCAGTCGTGGTTGCTGAAGATCCGCT
GACCTGCGTAGCGCGTGGCGGCGGCAAGGCGCTGGAGATGATCGACATGCACGGCGGCGACCTGTTTAGCGAAGAGTAG

Upstream 100 bases:

>100_bases
GAGCGCTGCTGAAGATTTCAGCAATGAACGGAGTCGGGAAAATTTGTAACAAAGGAAATGAACTGCACTAATTTTCACCG
CAGCAGGTGATTTTTGCGCC

Downstream 100 bases:

>100_bases
TCAGCCTGAAGGTCCGGGGCGGCATACGAGCTGCCCCTGGTCTTTACTGACACGAGAATACGCATAGCCTATGAAGCCAA
TTTTTAGCCGTGGCCCCTCG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MSLLRVVGKVSGFCFPPQLSGLSLSMLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAV
GHEAKQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGA
REVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAVINYVRRNYGSLIGEATA
ERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTG
GGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE

Sequences:

>Translated_372_residues
MSLLRVVGKVSGFCFPPQLSGLSLSMLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAV
GHEAKQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGA
REVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAVINYVRRNYGSLIGEATA
ERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTG
GGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE
>Mature_371_residues
SLLRVVGKVSGFCFPPQLSGLSLSMLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVG
HEAKQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAR
EVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAVINYVRRNYGSLIGEATAE
RIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGG
GALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=347, Percent_Identity=99.4236311239193, Blast_Score=693, Evalue=0.0,
Organism=Escherichia coli, GI1786870, Length=176, Percent_Identity=30.1136363636364, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 39558; Mature: 39427

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLRVVGKVSGFCFPPQLSGLSLSMLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNE
CHHHHHHHHHCCEECCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCEEEEEECCEEEECC
PSVVAIRQDRAGSPKSVAAVGHEAKQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFI
CCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
KQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPV
HHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCC
SEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAVINYVRRNYGSLIGEATA
CCCCCCEEEEECCCCEEEEEEEECCEEEECEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
ERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVAL
HHHHHHHCCCCCCCCEEEEEECCCHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHH
EQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEM
HHCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCEEEE
IDMHGGDLFSEE
EECCCCCCCCCC
>Mature Secondary Structure 
SLLRVVGKVSGFCFPPQLSGLSLSMLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNE
HHHHHHHHHCCEECCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCEEEEEECCEEEECC
PSVVAIRQDRAGSPKSVAAVGHEAKQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFI
CCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
KQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPV
HHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCC
SEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAVINYVRRNYGSLIGEATA
CCCCCCEEEEECCCCEEEEEEEECCEEEECEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
ERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVAL
HHHHHHHCCCCCCCCEEEEEECCCHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHH
EQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEM
HHCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCEEEE
IDMHGGDLFSEE
EECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]