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The map label for this gene is nanE [H]

Identifier: 238896723

GI number: 238896723

Start: 4703617

End: 4704321

Strand: Reverse

Name: nanE [H]

Synonym: KP1_4938

Alternate gene names: 238896723

Gene position: 4704321-4703617 (Counterclockwise)

Preceding gene: 238896724

Following gene: 238896720

Centisome position: 89.63

GC content: 61.84

Gene sequence:

>705_bases
ATGTCTTTACTCGCACAACTGGACCAGCGTATCCGTCATCATGGCGGATTAATTGTCTCCTGCCAGCCGGTGCCGGGCAG
TCCGCTGGATAATCCCGCTATCGTCGCGGCAATGGCGCTGGCGGCTGAGCAGGCGGGAGCGGTAGCGCTGCGCATCGAAG
GCCAGGCCAACCTGCAGGCCGTTCGTCCGTTAGTGACGGTGCCCGTTATTGGGTTGATCAAACGCGATTTGCCCGATAGC
CCGGTGCGTATTACGCCATGGCTGGAAGATATCGACGCGCTGGCGCAGGGCGGAGCGGATATTATTGCTATTGACGGCAC
CCAGCGTCAGCGTCCGGCGTCAGTGTCGGCGCTATTAGCAGAAATTCATCAGCTGGGAAAAGTGGCGATGGCCGATTGCT
CATCTCTCGACGATGCTCTCGAGTGCTGGCAGTTGGGGGCTGAGATTGTCGGGACGACTCTCTCCGGCTATACCGCAGAG
GAGACGCCGGAGGAGCCGGATCTGGCGCTGGTGCAATGCCTGAGCGTGGCGGGCTGCAGAGTGATTGCCGAAGGGCGCTA
TAACACGCCTGCCCAGGCGGCGGAGGCGATGCGCTGCGGCGCGTGGGCGGTGACCGTCGGCTCGGCGATTACCCGCCTGG
AGCATATCTGCGGCTGGTATAATACGGCGCTGAAAGCGGCGGTTTGCCCGGCGAATGAGCAATAA

Upstream 100 bases:

>100_bases
GGGCCTGTTTTTTTGTCTGTCCGCTTTGTTAACTCTGCCACAAACGAGGCGTCCCATGGCTGGTATCGTCATCGCCACAG
GTAGTTTTTAGGGAGCAGAC

Downstream 100 bases:

>100_bases
AAAAGCCCGATGACGTTAACCATCGGGCTTTTATGCGTGAGGCTCCGGACCTAATCAGACTTCAAGGTAGTTGAGGATCC
CGTCCGCCGCTTTACGGCCT

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSLLAQLDQRIRHHGGLIVSCQPVPGSPLDNPAIVAAMALAAEQAGAVALRIEGQANLQAVRPLVTVPVIGLIKRDLPDS
PVRITPWLEDIDALAQGGADIIAIDGTQRQRPASVSALLAEIHQLGKVAMADCSSLDDALECWQLGAEIVGTTLSGYTAE
ETPEEPDLALVQCLSVAGCRVIAEGRYNTPAQAAEAMRCGAWAVTVGSAITRLEHICGWYNTALKAAVCPANEQ

Sequences:

>Translated_234_residues
MSLLAQLDQRIRHHGGLIVSCQPVPGSPLDNPAIVAAMALAAEQAGAVALRIEGQANLQAVRPLVTVPVIGLIKRDLPDS
PVRITPWLEDIDALAQGGADIIAIDGTQRQRPASVSALLAEIHQLGKVAMADCSSLDDALECWQLGAEIVGTTLSGYTAE
ETPEEPDLALVQCLSVAGCRVIAEGRYNTPAQAAEAMRCGAWAVTVGSAITRLEHICGWYNTALKAAVCPANEQ
>Mature_233_residues
SLLAQLDQRIRHHGGLIVSCQPVPGSPLDNPAIVAAMALAAEQAGAVALRIEGQANLQAVRPLVTVPVIGLIKRDLPDSP
VRITPWLEDIDALAQGGADIIAIDGTQRQRPASVSALLAEIHQLGKVAMADCSSLDDALECWQLGAEIVGTTLSGYTAEE
TPEEPDLALVQCLSVAGCRVIAEGRYNTPAQAAEAMRCGAWAVTVGSAITRLEHICGWYNTALKAAVCPANEQ

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential) [H]

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family [H]

Homologues:

Organism=Escherichia coli, GI1789617, Length=228, Percent_Identity=77.1929824561403, Blast_Score=332, Evalue=1e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060 [H]

Pfam domain/function: PF04131 NanE [H]

EC number: =5.1.3.9 [H]

Molecular weight: Translated: 24544; Mature: 24413

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLAQLDQRIRHHGGLIVSCQPVPGSPLDNPAIVAAMALAAEQAGAVALRIEGQANLQA
CCHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHH
VRPLVTVPVIGLIKRDLPDSPVRITPWLEDIDALAQGGADIIAIDGTQRQRPASVSALLA
HHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHH
EIHQLGKVAMADCSSLDDALECWQLGAEIVGTTLSGYTAEETPEEPDLALVQCLSVAGCR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCE
VIAEGRYNTPAQAAEAMRCGAWAVTVGSAITRLEHICGWYNTALKAAVCPANEQ
EEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SLLAQLDQRIRHHGGLIVSCQPVPGSPLDNPAIVAAMALAAEQAGAVALRIEGQANLQA
CHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHH
VRPLVTVPVIGLIKRDLPDSPVRITPWLEDIDALAQGGADIIAIDGTQRQRPASVSALLA
HHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHH
EIHQLGKVAMADCSSLDDALECWQLGAEIVGTTLSGYTAEETPEEPDLALVQCLSVAGCR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCE
VIAEGRYNTPAQAAEAMRCGAWAVTVGSAITRLEHICGWYNTALKAAVCPANEQ
EEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11673431 [H]