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The map label for this gene is agaR [H]

Identifier: 238896651

GI number: 238896651

Start: 4630616

End: 4631389

Strand: Direct

Name: agaR [H]

Synonym: KP1_4856

Alternate gene names: 238896651

Gene position: 4630616-4631389 (Clockwise)

Preceding gene: 238896650

Following gene: 238896654

Centisome position: 88.23

GC content: 53.88

Gene sequence:

>774_bases
ATGAACTCATTTGAACGAAGGAACAAAATTGTCGATATGGTGAATACGCAGGGTAGCGTATTGGTTCTAGACCTTTCGAA
TCTCTTTGGCATCTCTGAGGTAACGATCCGTGCCGATCTCCGCTTACTGGAAGAAAAAGGACTGTTAACCCGTTTTCACG
GCGGCGCCGCCCGTGCGGGTAGCGACCTGACCGACGCCGAGAATCAGGAAGTGGTGCTTGAAGACCGCTATCAGCTTGCC
AGCGATCCCAAAAAGCGCATCGCCCATGCCGCGGCAGCGATGATCCGTGAAGGTATGACGGTGATCCTCGATAGCGGTAG
CACCACTCTTCTTATCGCCGAGGCATTAGTACGGATGACCAATATCACCGTCATCACCAACAGCCTGCCCGCCGCGTTTA
CTCTGGCAGAAAATAAAGATATCACCCTGGTGGTGTGCGGTGGTACCGTGCGGCACAAAACGCATTCGATGCACGGCACG
ATTGCCGAACGTTCGCTGCAAGGTATTTGCGCCGATTTGATGTTTGTCGGCGCCGACGGTATCGACGCCACCAATGGCAT
CACCACCTTTAACGAAGGCTACTCCATCAGCAGCGTGATGGCCGCCGCCGCGCATCAGGTGATCGCCGTGCTCGACGCCA
GCAAATTCAATCGCCGGGGCTTTAACCAGGTACTGCCGATGGAAAAGATAGACTGCGTGATCACCGACGACGGCATTAGT
GAAAATGACCGTGCAGCGTTAAGCAGCAAAAAGGTGGAACTGAAGATAGTGTAA

Upstream 100 bases:

>100_bases
CAGCCATCAGCGCTGGCTCATCCAACCTTTCGAAAATTATCGTTCACCTTTCGTTACCCTTCGATTACACTGAGATGAGT
TAATTATCAGGCAAATCAAG

Downstream 100 bases:

>100_bases
TTGCACGCTGAGTGGAACATCATGGCGGCTGGTTCTACTTAACCAGCCAGCTTCCACCTTTTTTGGCGCCTATGCGAATC
AATCTCCCTTTCGCCTGTAG

Product: putative DeoR-type transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MNSFERRNKIVDMVNTQGSVLVLDLSNLFGISEVTIRADLRLLEEKGLLTRFHGGAARAGSDLTDAENQEVVLEDRYQLA
SDPKKRIAHAAAAMIREGMTVILDSGSTTLLIAEALVRMTNITVITNSLPAAFTLAENKDITLVVCGGTVRHKTHSMHGT
IAERSLQGICADLMFVGADGIDATNGITTFNEGYSISSVMAAAAHQVIAVLDASKFNRRGFNQVLPMEKIDCVITDDGIS
ENDRAALSSKKVELKIV

Sequences:

>Translated_257_residues
MNSFERRNKIVDMVNTQGSVLVLDLSNLFGISEVTIRADLRLLEEKGLLTRFHGGAARAGSDLTDAENQEVVLEDRYQLA
SDPKKRIAHAAAAMIREGMTVILDSGSTTLLIAEALVRMTNITVITNSLPAAFTLAENKDITLVVCGGTVRHKTHSMHGT
IAERSLQGICADLMFVGADGIDATNGITTFNEGYSISSVMAAAAHQVIAVLDASKFNRRGFNQVLPMEKIDCVITDDGIS
ENDRAALSSKKVELKIV
>Mature_257_residues
MNSFERRNKIVDMVNTQGSVLVLDLSNLFGISEVTIRADLRLLEEKGLLTRFHGGAARAGSDLTDAENQEVVLEDRYQLA
SDPKKRIAHAAAAMIREGMTVILDSGSTTLLIAEALVRMTNITVITNSLPAAFTLAENKDITLVVCGGTVRHKTHSMHGT
IAERSLQGICADLMFVGADGIDATNGITTFNEGYSISSVMAAAAHQVIAVLDASKFNRRGFNQVLPMEKIDCVITDDGIS
ENDRAALSSKKVELKIV

Specific function: Repressor of the gat operon for galacticol transport and metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=254, Percent_Identity=37.7952755905512, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1789059, Length=257, Percent_Identity=37.3540856031128, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI226510968, Length=255, Percent_Identity=31.7647058823529, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789829, Length=261, Percent_Identity=30.2681992337165, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787540, Length=260, Percent_Identity=31.9230769230769, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1788069, Length=237, Percent_Identity=32.0675105485232, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082344, Length=251, Percent_Identity=28.2868525896414, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789170, Length=236, Percent_Identity=30.5084745762712, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1787063, Length=238, Percent_Identity=25.6302521008403, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790753, Length=222, Percent_Identity=27.9279279279279, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790635, Length=244, Percent_Identity=25, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27704; Mature: 27704

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2 ; PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSFERRNKIVDMVNTQGSVLVLDLSNLFGISEVTIRADLRLLEEKGLLTRFHGGAARAG
CCCHHHHHHHHHEECCCCCEEEEECCHHCCCEEEEEHHHHHHHHHCCCEEEECCCCCCCC
SDLTDAENQEVVLEDRYQLASDPKKRIAHAAAAMIREGMTVILDSGSTTLLIAEALVRMT
CCCCCCCCCEEEEECHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCEEHHHHHHHHHH
NITVITNSLPAAFTLAENKDITLVVCGGTVRHKTHSMHGTIAERSLQGICADLMFVGADG
CEEEEECCCCCEEEEECCCCEEEEEECCCCCCHHHHHCCHHHHHHHHHHHHHHHEECCCC
IDATNGITTFNEGYSISSVMAAAAHQVIAVLDASKFNRRGFNQVLPMEKIDCVITDDGIS
CCCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCHHCCCCCCCCEEEECCCCC
ENDRAALSSKKVELKIV
CCCHHHHCCCCEEEEEC
>Mature Secondary Structure
MNSFERRNKIVDMVNTQGSVLVLDLSNLFGISEVTIRADLRLLEEKGLLTRFHGGAARAG
CCCHHHHHHHHHEECCCCCEEEEECCHHCCCEEEEEHHHHHHHHHCCCEEEECCCCCCCC
SDLTDAENQEVVLEDRYQLASDPKKRIAHAAAAMIREGMTVILDSGSTTLLIAEALVRMT
CCCCCCCCCEEEEECHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCEEHHHHHHHHHH
NITVITNSLPAAFTLAENKDITLVVCGGTVRHKTHSMHGTIAERSLQGICADLMFVGADG
CEEEEECCCCCEEEEECCCCEEEEEECCCCCCHHHHHCCHHHHHHHHHHHHHHHEECCCC
IDATNGITTFNEGYSISSVMAAAAHQVIAVLDASKFNRRGFNQVLPMEKIDCVITDDGIS
CCCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCHHCCCCCCCCEEEECCCCC
ENDRAALSSKKVELKIV
CCCHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 7772602; 1661252 [H]