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The map label for this gene is yqhD [H]

Identifier: 238896524

GI number: 238896524

Start: 4502836

End: 4503999

Strand: Direct

Name: yqhD [H]

Synonym: KP1_4711

Alternate gene names: 238896524

Gene position: 4502836-4503999 (Clockwise)

Preceding gene: 238896522

Following gene: 238896525

Centisome position: 85.79

GC content: 59.45

Gene sequence:

>1164_bases
ATGAATAATTTCGACCTGCATACCCCAACCCGCATTCTGTTTGGCAAAGGCGCGATTGAAAAGCTGCGTGAACAGATCCC
GGCGGAAGCCCGCGTACTGATCACCTACGGCGGCGGCAGCGTCAAAAAAACAGGCGTCCTGGATCAGGTCCTCACCGCTC
TGAATGGCCTGGATGTCCTTGAATTTGGCGGCATCGAGCCGAACCCGTCTTACGAAACCCTGATGAATGCGGTGAAACTC
GCCCGGGAAGAGAAAGTGACCTTCCTGCTGGCGGTCGGCGGCGGTTCGGTGCTGGATGGCACCAAGTTTATCGCTGCAGC
AGCCCACTACGACGCGGATATCGATCCGTGGGAAATTCTGGAAACCTATGGCAGCAAAATTGCCAGCGCCATTCCAATGG
GCTCGGTACTGACTCTGCCGGCGACTGGTTCTGAATCCAACAAAGGCGCGGTCATATCGCGGAAAACCACCGGCGACAAA
CGCGCGTTTATGTCTTCGCACGTCCAGCCGCAGTTCGCGATCCTCGATCCGGTTTATACCTACACCCTGCCGCCGCGCCA
GGTCGCGAACGGCGTGGTTGACGCCTTCGTCCATACCGTCGAGCAGTACGTGACCTACCCGGTAGACGGCAAAATCCAGG
ACCGCTTCGCCGAAGGCATTCTCCTGACCCTGATCGAGGATGGCCCGAAAGCCCTGCAGGAACCGGAGAACTATAACGTG
CGCGCCAATATTATGTGGGCGGCGACGCAGGCGCTGAACGGCCTGATCGGCGCAGGCGTGCCACAGGACTGGGCGACGCA
TATGCTCGGCCACGAGCTGACGGCGATGCACGGCCTGGATCACGCCCAGACGCTGGCTATCGTGCTGCCGGCGCTGTGGA
ATGAGAAACGCGATGCCAAGCGCGAGAAGCTGCTGCAGTATGCCGAGCGCGTGTGGAATATTACCGAAGGCTCTGACGAC
CAACGTATCGATGCCGCCATCGCCGCAACGCGTCAGTTCTTCGAGCAGATGGGCGTGCCGACCCGCCTTTCCGATTACGG
TCTCGACGGTAGCTCCATCCCGGCGCTGCTGGCGAAACTGGAAGAGCACGGCATGACTAAACTTGGCGAACATCAGGATA
TCACCCTGGACGTCAGCCGCCGTATTTACGAGGCTGCACGCTAA

Upstream 100 bases:

>100_bases
GAATGTGCATTGAGGGTCAACGGCGCCAGGACCACAATAACCTTCATCGGGCAGCGGTATCATCCCTGTCGACGGTTTTA
CTCTTTGGAGGACTTAAGCA

Downstream 100 bases:

>100_bases
GCGCTCCCCGCCTGATTCACCTCTCCTTACGTTAAACAAACGCCGGGGAGAGGTGTTTTTACTACCGTTTTTAGCTATTT
CGTCCAGACTTAATGCTACC

Product: putative alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNNFDLHTPTRILFGKGAIEKLREQIPAEARVLITYGGGSVKKTGVLDQVLTALNGLDVLEFGGIEPNPSYETLMNAVKL
AREEKVTFLLAVGGGSVLDGTKFIAAAAHYDADIDPWEILETYGSKIASAIPMGSVLTLPATGSESNKGAVISRKTTGDK
RAFMSSHVQPQFAILDPVYTYTLPPRQVANGVVDAFVHTVEQYVTYPVDGKIQDRFAEGILLTLIEDGPKALQEPENYNV
RANIMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDAKREKLLQYAERVWNITEGSDD
QRIDAAIAATRQFFEQMGVPTRLSDYGLDGSSIPALLAKLEEHGMTKLGEHQDITLDVSRRIYEAAR

Sequences:

>Translated_387_residues
MNNFDLHTPTRILFGKGAIEKLREQIPAEARVLITYGGGSVKKTGVLDQVLTALNGLDVLEFGGIEPNPSYETLMNAVKL
AREEKVTFLLAVGGGSVLDGTKFIAAAAHYDADIDPWEILETYGSKIASAIPMGSVLTLPATGSESNKGAVISRKTTGDK
RAFMSSHVQPQFAILDPVYTYTLPPRQVANGVVDAFVHTVEQYVTYPVDGKIQDRFAEGILLTLIEDGPKALQEPENYNV
RANIMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDAKREKLLQYAERVWNITEGSDD
QRIDAAIAATRQFFEQMGVPTRLSDYGLDGSSIPALLAKLEEHGMTKLGEHQDITLDVSRRIYEAAR
>Mature_387_residues
MNNFDLHTPTRILFGKGAIEKLREQIPAEARVLITYGGGSVKKTGVLDQVLTALNGLDVLEFGGIEPNPSYETLMNAVKL
AREEKVTFLLAVGGGSVLDGTKFIAAAAHYDADIDPWEILETYGSKIASAIPMGSVLTLPATGSESNKGAVISRKTTGDK
RAFMSSHVQPQFAILDPVYTYTLPPRQVANGVVDAFVHTVEQYVTYPVDGKIQDRFAEGILLTLIEDGPKALQEPENYNV
RANIMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDAKREKLLQYAERVWNITEGSDD
QRIDAAIAATRQFFEQMGVPTRLSDYGLDGSSIPALLAKLEEHGMTKLGEHQDITLDVSRRIYEAAR

Specific function: NADP-dependent ADH activity [H]

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=355, Percent_Identity=23.0985915492958, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789386, Length=387, Percent_Identity=88.8888888888889, Blast_Score=709, Evalue=0.0,
Organism=Escherichia coli, GI48994951, Length=312, Percent_Identity=26.2820512820513, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082107, Length=279, Percent_Identity=27.2401433691756, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1789163, Length=382, Percent_Identity=24.3455497382199, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787493, Length=345, Percent_Identity=25.5072463768116, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321181, Length=367, Percent_Identity=25.0681198910082, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24657991, Length=368, Percent_Identity=23.6413043478261, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 42294; Mature: 42294

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNFDLHTPTRILFGKGAIEKLREQIPAEARVLITYGGGSVKKTGVLDQVLTALNGLDVL
CCCCCCCCCCCEEECCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEE
EFGGIEPNPSYETLMNAVKLAREEKVTFLLAVGGGSVLDGTKFIAAAAHYDADIDPWEIL
CCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCHHHHH
ETYGSKIASAIPMGSVLTLPATGSESNKGAVISRKTTGDKRAFMSSHVQPQFAILDPVYT
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHCCCCCEEEECCHHE
YTLPPRQVANGVVDAFVHTVEQYVTYPVDGKIQDRFAEGILLTLIEDGPKALQEPENYNV
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEEECCCHHHHCCCCCCCE
RANIMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDAK
EEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHH
REKLLQYAERVWNITEGSDDQRIDAAIAATRQFFEQMGVPTRLSDYGLDGSSIPALLAKL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHH
EEHGMTKLGEHQDITLDVSRRIYEAAR
HHCCCCCCCCCCCEEEHHHHHHHHHCC
>Mature Secondary Structure
MNNFDLHTPTRILFGKGAIEKLREQIPAEARVLITYGGGSVKKTGVLDQVLTALNGLDVL
CCCCCCCCCCCEEECCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEE
EFGGIEPNPSYETLMNAVKLAREEKVTFLLAVGGGSVLDGTKFIAAAAHYDADIDPWEIL
CCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCHHHHH
ETYGSKIASAIPMGSVLTLPATGSESNKGAVISRKTTGDKRAFMSSHVQPQFAILDPVYT
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHCCCCCEEEECCHHE
YTLPPRQVANGVVDAFVHTVEQYVTYPVDGKIQDRFAEGILLTLIEDGPKALQEPENYNV
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEEECCCHHHHCCCCCCCE
RANIMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDAK
EEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHH
REKLLQYAERVWNITEGSDDQRIDAAIAATRQFFEQMGVPTRLSDYGLDGSSIPALLAKL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHH
EEHGMTKLGEHQDITLDVSRRIYEAAR
HHCCCCCCCCCCCEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]