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The map label for this gene is yggW [H]

Identifier: 238896486

GI number: 238896486

Start: 4465501

End: 4466640

Strand: Direct

Name: yggW [H]

Synonym: KP1_4666

Alternate gene names: 238896486

Gene position: 4465501-4466640 (Clockwise)

Preceding gene: 238896485

Following gene: 238896487

Centisome position: 85.08

GC content: 60.0

Gene sequence:

>1140_bases
ATGGCTAATTTGCCGCCGCTGAGTCTCTATATCCATATTCCCTGGTGCGTGCAGAAATGCCCGTACTGCGATTTTAATTC
GCATGCGCTGAAAGGCGAGGTGCCGCATGATGACTACGTCCAGCATCTGCTGAACGATCTGCAGGCTGATGCGCACTATG
CCCAGGGACGGGAAATAGGCACTATTTTTATCGGCGGCGGAACGCCGAGCCTGCTGTCCGGCCTGGCCATGCAAACCCTG
CTCGATGGCGTCCGCGCCTGCCTGCCGCTGGCCGCCGGGGCGGAAATCACCATGGAAGCCAACCCGGGTACCGTGGAGGC
CGATCGCTTCGTTGATTATCAGCGCGCCGGGGTGAACCGCATCTCCATCGGCGTACAAAGCTTTAGCGAACCGAAGCTGC
AGCGCCTGGGGCGGATCCACGGCCCGGAGGAGGCCAAGCGCGCAGCACGTCTCGCCAGCGGCCTCGGCTTGCGCAGCTTC
AACCTCGACCTGATGCACGGTCTGCCGGACCAGTCGCTGGAGGAGGCGCTGGACGATCTGCGTCAGGCGATTGCCCTCAA
CCCGCCGCACCTGTCGTGGTACCAGCTGACCATTGAGCCGAACACCTTGTTCGGCTCCCGGCCGCCGGTGCTGCCGGATG
ACGACGCGCTATGGGATATTTTCGAGCAGGGGCATCAGCTGCTGAGCGCCGCCGGCTATCAGCAGTACGAGACGTCCGCC
TATGCTAAGCCAGGCTTCCAGTGTCAGCATAATCTCAACTACTGGCGCTTTGGCGACTACCTCGGCATCGGCTGCGGCGC
GCACGGCAAGATCACCTTCCCTGACGGACGCATTCTGCGAACCGCCAAAACCCGCCACCCGCGCGGGTATATGGAAGGCC
GTTACCTTGAGCGTCAGCATGATGTGGAAGAAGCGGATAAACCGTTTGAGTTCTTTATGAACCGTTTTCGCCTGCTGGAG
GCCGCGCCGCGTGCGGAGTTCAGCTTGTATACCGGCCTTGATGAGCAGGTTATCCGTCAGCAAATCGATGCCGCTATCGC
CGAAGGCTATCTGCTGGAAGATGCGCAAAACTGGCAAATTACCGAGCACGGTAAACTGTTTTTAAATTCGCTGCTGGAGC
TGTTCCTCAGCGAAGAGTAA

Upstream 100 bases:

>100_bases
CCGTCAGAAGGGAAAACCGCGGCCGAACTGAGCCGTGAAGAAAAGAGCGCCATTTCCCATCGCGGGCAGGCGCTGAAACT
GTTACTGGAAGCATTACGTA

Downstream 100 bases:

>100_bases
TCCCTGCGGGCGGCACGTCGTCGCCCGTATCTTTCCCCTTACATCCTCTCCCGCTACGGTCAAATCGACTGGCGTTTTTT
TGTTCACTTATTTGCAGCGA

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MANLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLQADAHYAQGREIGTIFIGGGTPSLLSGLAMQTL
LDGVRACLPLAAGAEITMEANPGTVEADRFVDYQRAGVNRISIGVQSFSEPKLQRLGRIHGPEEAKRAARLASGLGLRSF
NLDLMHGLPDQSLEEALDDLRQAIALNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALWDIFEQGHQLLSAAGYQQYETSA
YAKPGFQCQHNLNYWRFGDYLGIGCGAHGKITFPDGRILRTAKTRHPRGYMEGRYLERQHDVEEADKPFEFFMNRFRLLE
AAPRAEFSLYTGLDEQVIRQQIDAAIAEGYLLEDAQNWQITEHGKLFLNSLLELFLSEE

Sequences:

>Translated_379_residues
MANLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLQADAHYAQGREIGTIFIGGGTPSLLSGLAMQTL
LDGVRACLPLAAGAEITMEANPGTVEADRFVDYQRAGVNRISIGVQSFSEPKLQRLGRIHGPEEAKRAARLASGLGLRSF
NLDLMHGLPDQSLEEALDDLRQAIALNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALWDIFEQGHQLLSAAGYQQYETSA
YAKPGFQCQHNLNYWRFGDYLGIGCGAHGKITFPDGRILRTAKTRHPRGYMEGRYLERQHDVEEADKPFEFFMNRFRLLE
AAPRAEFSLYTGLDEQVIRQQIDAAIAEGYLLEDAQNWQITEHGKLFLNSLLELFLSEE
>Mature_378_residues
ANLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLQADAHYAQGREIGTIFIGGGTPSLLSGLAMQTLL
DGVRACLPLAAGAEITMEANPGTVEADRFVDYQRAGVNRISIGVQSFSEPKLQRLGRIHGPEEAKRAARLASGLGLRSFN
LDLMHGLPDQSLEEALDDLRQAIALNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALWDIFEQGHQLLSAAGYQQYETSAY
AKPGFQCQHNLNYWRFGDYLGIGCGAHGKITFPDGRILRTAKTRHPRGYMEGRYLERQHDVEEADKPFEFFMNRFRLLEA
APRAEFSLYTGLDEQVIRQQIDAAIAEGYLLEDAQNWQITEHGKLFLNSLLELFLSEE

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=284, Percent_Identity=35.5633802816901, Blast_Score=166, Evalue=3e-41,
Organism=Escherichia coli, GI1789325, Length=378, Percent_Identity=88.8888888888889, Blast_Score=697, Evalue=0.0,
Organism=Escherichia coli, GI87082341, Length=245, Percent_Identity=33.0612244897959, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 42565; Mature: 42433

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLQADAHYAQGREIG
CCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEE
TIFIGGGTPSLLSGLAMQTLLDGVRACLPLAAGAEITMEANPGTVEADRFVDYQRAGVNR
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCE
ISIGVQSFSEPKLQRLGRIHGPEEAKRAARLASGLGLRSFNLDLMHGLPDQSLEEALDDL
EEECHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECHHHHCCCCCHHHHHHHHHH
RQAIALNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALWDIFEQGHQLLSAAGYQQYETSA
HHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
YAKPGFQCQHNLNYWRFGDYLGIGCGAHGKITFPDGRILRTAKTRHPRGYMEGRYLERQH
CCCCCCCCCCCCCEEEECCEEEECCCCCCEEECCCCCEEECCCCCCCCCCCCCCHHHHHC
DVEEADKPFEFFMNRFRLLEAAPRAEFSLYTGLDEQVIRQQIDAAIAEGYLLEDAQNWQI
CHHHCCCCHHHHHHHHHHHHHCCCCCEEHHCCCHHHHHHHHHHHHHHCCEEEECCCCCEE
TEHGKLFLNSLLELFLSEE
CHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLQADAHYAQGREIG
CCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEE
TIFIGGGTPSLLSGLAMQTLLDGVRACLPLAAGAEITMEANPGTVEADRFVDYQRAGVNR
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCE
ISIGVQSFSEPKLQRLGRIHGPEEAKRAARLASGLGLRSFNLDLMHGLPDQSLEEALDDL
EEECHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECHHHHCCCCCHHHHHHHHHH
RQAIALNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALWDIFEQGHQLLSAAGYQQYETSA
HHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
YAKPGFQCQHNLNYWRFGDYLGIGCGAHGKITFPDGRILRTAKTRHPRGYMEGRYLERQH
CCCCCCCCCCCCCEEEECCEEEECCCCCCEEECCCCCEEECCCCCCCCCCCCCCHHHHHC
DVEEADKPFEFFMNRFRLLEAAPRAEFSLYTGLDEQVIRQQIDAAIAEGYLLEDAQNWQI
CHHHCCCCHHHHHHHHHHHHHCCCCCEEHHCCCHHHHHHHHHHHHHHCCEEEECCCCCEE
TEHGKLFLNSLLELFLSEE
CHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]