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The map label for this gene is yajO [H]

Identifier: 238896424

GI number: 238896424

Start: 4402433

End: 4403452

Strand: Direct

Name: yajO [H]

Synonym: KP1_4599

Alternate gene names: 238896424

Gene position: 4402433-4403452 (Clockwise)

Preceding gene: 238896423

Following gene: 238896425

Centisome position: 83.88

GC content: 58.92

Gene sequence:

>1020_bases
ATGCAGTATACCCGGCTCGGGAAGAGTGACTTACTGGTCTCCCGTATCTGCATGGGATGTATGGGGTTTGGCGATCCGTC
AACGGGTCAGCATCGCTGGACGCTGGACGAAACAGCCAGCCGGGACATCATCCGCCACGCTCTGGAACAGGGCATCAATT
TTTACGATACCGCCATCGCCTATCAGAACGGCTCCAGCGAACGGTACGTTGGCCGGGCGCTGCGGGAGATGGCAAAACGC
GAGGAGGTGGTGCTGGCCACCAAGTTTCTGCCACGAACCGCTGCCCAGATTGCCGAGGGGATCAGCGGAAAACAGGCGAT
AGCCCGCTCGCTTGACCAGAGTCTGCGAAACCTCGGGATGGACTACATCGACCTCTACATCTACCACATCTGGGATTACA
ACACCCCGGTTATCGACGTGCTGGAGGCGCTGCACACCGCAGTGACCGCCGGCAAGGTGCGCGCGATTGGCATTTCCAAT
TGCTATGCCTGGCAGTTGGCGAAGGCGAACGCCCTTGCCGAACGCGAAGGGCTGACATCCTTTGTTTCTGTGCAGAGCCA
CTACAACCTGATTATGCGTGAAGATGAACGAGAGCTGTTCGGGCTGTGCGCAGAAGAGGGTATCGCCATGACTCCCTATA
GCGCGCTGGCCAGCGGCCGTCTCTCCCGCTTAGAAGGCCACACGCGGCGAGCGGTGGAAGATGATTATGCCCGGGGCAAA
TACGACGGCACGGCAGAACAGGACCGGATCATTATTGCCCGCGTCGCTGAACTTGCCGAACGGCATCAGGTCTCGATGAC
CGAAATTTCGCTGGCCTGGCTGCTGATAAAAGTCACCGCCCCGGTGATCGGCGCCACGCAAAAACATCATGTTGACGGCG
CGGTCAACGCTGTAGCCCTTCAACTGAGCCCGGAAGACATCCGTTATCTGGAAGAAGCCTATCCGCCGCACTTCCTCACA
GGCGTGATGGCGCAAAACACGCCGCAAGCCAAAGACCGTCCTCAGGTGTGGACGCGCTAA

Upstream 100 bases:

>100_bases
ACAAAATCGCTCAGCAAAAAACGCTTGCCCGGGAACACGCGGCCAGACTGATCGCGCGGCTTAATACTCTGGTGGAATAA
CCCAAAGGGAGAAAATAACG

Downstream 100 bases:

>100_bases
CGATCCGCCCTGCGGATCGGAAAGGAGCAAATATGAAAAACGTGATTGCCGCGGCAGCCTTGTCGCTTGTGCTGTCTGAT
TTTACTTATGCCCACGAACA

Product: putative NAD(P)H-dependent xylose reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MQYTRLGKSDLLVSRICMGCMGFGDPSTGQHRWTLDETASRDIIRHALEQGINFYDTAIAYQNGSSERYVGRALREMAKR
EEVVLATKFLPRTAAQIAEGISGKQAIARSLDQSLRNLGMDYIDLYIYHIWDYNTPVIDVLEALHTAVTAGKVRAIGISN
CYAWQLAKANALAEREGLTSFVSVQSHYNLIMREDERELFGLCAEEGIAMTPYSALASGRLSRLEGHTRRAVEDDYARGK
YDGTAEQDRIIIARVAELAERHQVSMTEISLAWLLIKVTAPVIGATQKHHVDGAVNAVALQLSPEDIRYLEEAYPPHFLT
GVMAQNTPQAKDRPQVWTR

Sequences:

>Translated_339_residues
MQYTRLGKSDLLVSRICMGCMGFGDPSTGQHRWTLDETASRDIIRHALEQGINFYDTAIAYQNGSSERYVGRALREMAKR
EEVVLATKFLPRTAAQIAEGISGKQAIARSLDQSLRNLGMDYIDLYIYHIWDYNTPVIDVLEALHTAVTAGKVRAIGISN
CYAWQLAKANALAEREGLTSFVSVQSHYNLIMREDERELFGLCAEEGIAMTPYSALASGRLSRLEGHTRRAVEDDYARGK
YDGTAEQDRIIIARVAELAERHQVSMTEISLAWLLIKVTAPVIGATQKHHVDGAVNAVALQLSPEDIRYLEEAYPPHFLT
GVMAQNTPQAKDRPQVWTR
>Mature_339_residues
MQYTRLGKSDLLVSRICMGCMGFGDPSTGQHRWTLDETASRDIIRHALEQGINFYDTAIAYQNGSSERYVGRALREMAKR
EEVVLATKFLPRTAAQIAEGISGKQAIARSLDQSLRNLGMDYIDLYIYHIWDYNTPVIDVLEALHTAVTAGKVRAIGISN
CYAWQLAKANALAEREGLTSFVSVQSHYNLIMREDERELFGLCAEEGIAMTPYSALASGRLSRLEGHTRRAVEDDYARGK
YDGTAEQDRIIIARVAELAERHQVSMTEISLAWLLIKVTAPVIGATQKHHVDGAVNAVALQLSPEDIRYLEEAYPPHFLT
GVMAQNTPQAKDRPQVWTR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=318, Percent_Identity=28.6163522012579, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI27436962, Length=318, Percent_Identity=28.6163522012579, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI27436971, Length=320, Percent_Identity=28.75, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI27436969, Length=320, Percent_Identity=28.125, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4504825, Length=318, Percent_Identity=27.9874213836478, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI27436966, Length=318, Percent_Identity=28.3018867924528, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI223718702, Length=189, Percent_Identity=30.1587301587302, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI41152114, Length=189, Percent_Identity=29.6296296296296, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI41327764, Length=177, Percent_Identity=32.2033898305085, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87081735, Length=324, Percent_Identity=50, Blast_Score=313, Evalue=1e-86,
Organism=Escherichia coli, GI1788070, Length=334, Percent_Identity=29.3413173652695, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789199, Length=342, Percent_Identity=29.2397660818713, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789375, Length=313, Percent_Identity=31.3099041533546, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1788081, Length=303, Percent_Identity=29.7029702970297, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786400, Length=284, Percent_Identity=26.7605633802817, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17550248, Length=317, Percent_Identity=27.1293375394322, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17561298, Length=307, Percent_Identity=25.4071661237785, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17566692, Length=224, Percent_Identity=27.6785714285714, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=338, Percent_Identity=36.094674556213, Blast_Score=182, Evalue=6e-47,
Organism=Saccharomyces cerevisiae, GI6323998, Length=320, Percent_Identity=29.375, Blast_Score=142, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6319958, Length=299, Percent_Identity=29.4314381270903, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6319951, Length=321, Percent_Identity=27.4143302180685, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6322615, Length=253, Percent_Identity=30.4347826086957, Blast_Score=125, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6321052, Length=143, Percent_Identity=30.7692307692308, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24663317, Length=317, Percent_Identity=24.2902208201893, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129731, Length=309, Percent_Identity=24.2718446601942, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646155, Length=164, Percent_Identity=31.7073170731707, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37888; Mature: 37888

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYTRLGKSDLLVSRICMGCMGFGDPSTGQHRWTLDETASRDIIRHALEQGINFYDTAIA
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCHHHHHEE
YQNGSSERYVGRALREMAKREEVVLATKFLPRTAAQIAEGISGKQAIARSLDQSLRNLGM
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
DYIDLYIYHIWDYNTPVIDVLEALHTAVTAGKVRAIGISNCYAWQLAKANALAEREGLTS
HHHHEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCHHH
FVSVQSHYNLIMREDERELFGLCAEEGIAMTPYSALASGRLSRLEGHTRRAVEDDYARGK
HHHHHHHHHEEEECCHHHHHHHHHHCCCEECCHHHHHHHHHHHHCCHHHHHHHHHHHCCC
YDGTAEQDRIIIARVAELAERHQVSMTEISLAWLLIKVTAPVIGATQKHHVDGAVNAVAL
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEEE
QLSPEDIRYLEEAYPPHFLTGVMAQNTPQAKDRPQVWTR
EECHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQYTRLGKSDLLVSRICMGCMGFGDPSTGQHRWTLDETASRDIIRHALEQGINFYDTAIA
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCHHHHHEE
YQNGSSERYVGRALREMAKREEVVLATKFLPRTAAQIAEGISGKQAIARSLDQSLRNLGM
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
DYIDLYIYHIWDYNTPVIDVLEALHTAVTAGKVRAIGISNCYAWQLAKANALAEREGLTS
HHHHEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCHHH
FVSVQSHYNLIMREDERELFGLCAEEGIAMTPYSALASGRLSRLEGHTRRAVEDDYARGK
HHHHHHHHHEEEECCHHHHHHHHHHCCCEECCHHHHHHHHHHHHCCHHHHHHHHHHHCCC
YDGTAEQDRIIIARVAELAERHQVSMTEISLAWLLIKVTAPVIGATQKHHVDGAVNAVAL
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEEE
QLSPEDIRYLEEAYPPHFLTGVMAQNTPQAKDRPQVWTR
EECHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]