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The map label for this gene is yclF [H]

Identifier: 238896414

GI number: 238896414

Start: 4394804

End: 4396357

Strand: Reverse

Name: yclF [H]

Synonym: KP1_4589

Alternate gene names: 238896414

Gene position: 4396357-4394804 (Counterclockwise)

Preceding gene: 238896415

Following gene: 238896413

Centisome position: 83.76

GC content: 59.85

Gene sequence:

>1554_bases
ATGCATTCCTCTGTTAATAAAAACGAAAGCCGTACCTTTTTCGGCCATCCTTATCCGCTGGGCTCCCTGTTCTTCACTGA
AATGTGGGAGCGCTTCTCGTTTTACGGCATCCGTCCTTTACTGATCCTGTTTATGGCGGCGACAGTGTACGACGGCGGCA
TGGGCCTGGCGCGAGAGAACGCCTCGGCGATCGTTGGGATTTTTGCCGGCAGTATGTATCTCGCCGCGCTGCCGGGCGGC
TGGCTGGCGGATAACTGGCTTGGCCAACAACGCGCCGTCTGGTACGGCTCTATCCTGATCGCCCTGGGGCACCTGTCGAT
CGCTCTGTCAGCATGGCTGGGCAACGATCTGTTCTTTATCGGTCTGATGTTTATCGTCCTGGGTTCCGGGTTGTTTAAAA
CCTGTATCTCGGTGATGGTCGGCACCCTGTATAAAAAGGGCGACGCGCGCCGCGACGGTGGTTTTTCGCTGTTCTACATG
GGGATCAACATCGGCTCGTTTATCGCGCCATTGATCTCTGGCTGGCTTATCAAATCGCATGGCTGGCACTGGGGCTTCGG
CATCGGGGGGATCGGGATGCTGGTGGCGCTGATCATTTTCCGTGTCTTTGCCGTACCGTCGATGAAGCGCTATGACGCGG
AGGTTGGCCTCGATTCCACCTGGAACAGCCCGGTGGCGAAAAAGAATGGCGTTGGAGCGTGGCTGCTGGCGCTGGCGCTG
GGAGTGGCGGTGCTGGTCACGCTTATCAGCCTGGGCACGATCGTGATTAACCCGGTGGCGGTGGCCAGCGTGCTGGTCTA
TGTGATTGCCGCCTCCGTGGCGCTCTATTTCCTCTGGCTGTTCGTCTTCGCCGGACTCAACCGTAAAGAGCGGGCGCGCC
TGCTGGTATGCTTTATTTTGCTGGTCTCTGCGGCCTTTTTCTGGTCCGCGTTTGAACAGAAACCGACCTCCTTCAACCTG
TTTGCTAACGACTACACCAACCGGATGATCGGCGATTTTGAGATCCCCGCGGTCTGGTTCCAGTCGATTAACGCCTTGTT
TATCATTCTCCTCGCGCCGGTATTCAGCTGGGCGTGGCCTGCGCTGGCGCGTAAAAACGTTCGTCCGGGCAGTATGACCA
AATTCGTGATTGGCATCCTGTGCGCAGCGGCGGGCTTTGGCCTGATGATGCTGGCGGCGCAGAACGTTCTGAGCAACGGC
GGGGCCGGTGTGTCGCCGCTGTGGCTGGTGGGCAGCATCCTGATGCTGACGCTCGGTGAACTGTGCCTCAGCCCGATTGG
GCTGGCGACCATGACTCTGCTGGCGCCGGAGAGAATGCGCGGCCAGATGATGGGGCTGTGGTTCTGCGCCAGCGCGCTGG
GTAACCTGGCGGCGGGCCTGATCGGCGGTCATGTGAAGGCCGATCAGCTGTCGCTGCTGCCGGACCTCTTCGCCCGCTGC
TCCATCGCATTGCTGATCTGCGCCGCCGTGCTGGCCGTGCTGATTGTCCCGGTCCGCCGGATGCTGGAGAACAGCCGGTC
CAGCGCCGCGCAAAAATCCCTCAGCAACGCCTAA

Upstream 100 bases:

>100_bases
TAAAAATGCTCGTGTTTGATGTTAATACAAACAAATTATAAATCGTCAGCCTGCTTTATACGGTTAACTTGCGCTGCGGC
GCACCTTACCTGGAGAATTT

Downstream 100 bases:

>100_bases
CGCGATCCTCAGGCCGGCCCTACGGGGCCGGCTTGTTTTTTGTCCAATCCCCGCCCCAGCAGAACAAAATCCCCTTTTCA
CAATGCGCGATGTCCCATAA

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MHSSVNKNESRTFFGHPYPLGSLFFTEMWERFSFYGIRPLLILFMAATVYDGGMGLARENASAIVGIFAGSMYLAALPGG
WLADNWLGQQRAVWYGSILIALGHLSIALSAWLGNDLFFIGLMFIVLGSGLFKTCISVMVGTLYKKGDARRDGGFSLFYM
GINIGSFIAPLISGWLIKSHGWHWGFGIGGIGMLVALIIFRVFAVPSMKRYDAEVGLDSTWNSPVAKKNGVGAWLLALAL
GVAVLVTLISLGTIVINPVAVASVLVYVIAASVALYFLWLFVFAGLNRKERARLLVCFILLVSAAFFWSAFEQKPTSFNL
FANDYTNRMIGDFEIPAVWFQSINALFIILLAPVFSWAWPALARKNVRPGSMTKFVIGILCAAAGFGLMMLAAQNVLSNG
GAGVSPLWLVGSILMLTLGELCLSPIGLATMTLLAPERMRGQMMGLWFCASALGNLAAGLIGGHVKADQLSLLPDLFARC
SIALLICAAVLAVLIVPVRRMLENSRSSAAQKSLSNA

Sequences:

>Translated_517_residues
MHSSVNKNESRTFFGHPYPLGSLFFTEMWERFSFYGIRPLLILFMAATVYDGGMGLARENASAIVGIFAGSMYLAALPGG
WLADNWLGQQRAVWYGSILIALGHLSIALSAWLGNDLFFIGLMFIVLGSGLFKTCISVMVGTLYKKGDARRDGGFSLFYM
GINIGSFIAPLISGWLIKSHGWHWGFGIGGIGMLVALIIFRVFAVPSMKRYDAEVGLDSTWNSPVAKKNGVGAWLLALAL
GVAVLVTLISLGTIVINPVAVASVLVYVIAASVALYFLWLFVFAGLNRKERARLLVCFILLVSAAFFWSAFEQKPTSFNL
FANDYTNRMIGDFEIPAVWFQSINALFIILLAPVFSWAWPALARKNVRPGSMTKFVIGILCAAAGFGLMMLAAQNVLSNG
GAGVSPLWLVGSILMLTLGELCLSPIGLATMTLLAPERMRGQMMGLWFCASALGNLAAGLIGGHVKADQLSLLPDLFARC
SIALLICAAVLAVLIVPVRRMLENSRSSAAQKSLSNA
>Mature_517_residues
MHSSVNKNESRTFFGHPYPLGSLFFTEMWERFSFYGIRPLLILFMAATVYDGGMGLARENASAIVGIFAGSMYLAALPGG
WLADNWLGQQRAVWYGSILIALGHLSIALSAWLGNDLFFIGLMFIVLGSGLFKTCISVMVGTLYKKGDARRDGGFSLFYM
GINIGSFIAPLISGWLIKSHGWHWGFGIGGIGMLVALIIFRVFAVPSMKRYDAEVGLDSTWNSPVAKKNGVGAWLLALAL
GVAVLVTLISLGTIVINPVAVASVLVYVIAASVALYFLWLFVFAGLNRKERARLLVCFILLVSAAFFWSAFEQKPTSFNL
FANDYTNRMIGDFEIPAVWFQSINALFIILLAPVFSWAWPALARKNVRPGSMTKFVIGILCAAAGFGLMMLAAQNVLSNG
GAGVSPLWLVGSILMLTLGELCLSPIGLATMTLLAPERMRGQMMGLWFCASALGNLAAGLIGGHVKADQLSLLPDLFARC
SIALLICAAVLAVLIVPVRRMLENSRSSAAQKSLSNA

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=221, Percent_Identity=30.7692307692308, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI226371746, Length=205, Percent_Identity=32.1951219512195, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI226371748, Length=198, Percent_Identity=28.7878787878788, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1787922, Length=505, Percent_Identity=29.1089108910891, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI1789911, Length=517, Percent_Identity=29.0135396518375, Blast_Score=198, Evalue=8e-52,
Organism=Escherichia coli, GI1790572, Length=506, Percent_Identity=28.6561264822134, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1786927, Length=472, Percent_Identity=28.8135593220339, Blast_Score=174, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71987453, Length=388, Percent_Identity=27.0618556701031, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17569141, Length=415, Percent_Identity=23.855421686747, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28571102, Length=206, Percent_Identity=30.0970873786408, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571100, Length=206, Percent_Identity=30.0970873786408, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571098, Length=206, Percent_Identity=30.0970873786408, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24639585, Length=200, Percent_Identity=29, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24639583, Length=200, Percent_Identity=29, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24639581, Length=213, Percent_Identity=28.6384976525822, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 55814; Mature: 55814

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS50850 MFS ; PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSSVNKNESRTFFGHPYPLGSLFFTEMWERFSFYGIRPLLILFMAATVYDGGMGLAREN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCC
ASAIVGIFAGSMYLAALPGGWLADNWLGQQRAVWYGSILIALGHLSIALSAWLGNDLFFI
CHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GLMFIVLGSGLFKTCISVMVGTLYKKGDARRDGGFSLFYMGINIGSFIAPLISGWLIKSH
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCC
GWHWGFGIGGIGMLVALIIFRVFAVPSMKRYDAEVGLDSTWNSPVAKKNGVGAWLLALAL
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
GVAVLVTLISLGTIVINPVAVASVLVYVIAASVALYFLWLFVFAGLNRKERARLLVCFIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LVSAAFFWSAFEQKPTSFNLFANDYTNRMIGDFEIPAVWFQSINALFIILLAPVFSWAWP
HHHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALARKNVRPGSMTKFVIGILCAAAGFGLMMLAAQNVLSNGGAGVSPLWLVGSILMLTLGE
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LCLSPIGLATMTLLAPERMRGQMMGLWFCASALGNLAAGLIGGHVKADQLSLLPDLFARC
HHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SIALLICAAVLAVLIVPVRRMLENSRSSAAQKSLSNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHSSVNKNESRTFFGHPYPLGSLFFTEMWERFSFYGIRPLLILFMAATVYDGGMGLAREN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCC
ASAIVGIFAGSMYLAALPGGWLADNWLGQQRAVWYGSILIALGHLSIALSAWLGNDLFFI
CHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GLMFIVLGSGLFKTCISVMVGTLYKKGDARRDGGFSLFYMGINIGSFIAPLISGWLIKSH
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCC
GWHWGFGIGGIGMLVALIIFRVFAVPSMKRYDAEVGLDSTWNSPVAKKNGVGAWLLALAL
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
GVAVLVTLISLGTIVINPVAVASVLVYVIAASVALYFLWLFVFAGLNRKERARLLVCFIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LVSAAFFWSAFEQKPTSFNLFANDYTNRMIGDFEIPAVWFQSINALFIILLAPVFSWAWP
HHHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALARKNVRPGSMTKFVIGILCAAAGFGLMMLAAQNVLSNGGAGVSPLWLVGSILMLTLGE
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LCLSPIGLATMTLLAPERMRGQMMGLWFCASALGNLAAGLIGGHVKADQLSLLPDLFARC
HHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SIALLICAAVLAVLIVPVRRMLENSRSSAAQKSLSNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]