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The map label for this gene is mdtP [H]

Identifier: 238896412

GI number: 238896412

Start: 4392607

End: 4394055

Strand: Direct

Name: mdtP [H]

Synonym: KP1_4587

Alternate gene names: 238896412

Gene position: 4392607-4394055 (Clockwise)

Preceding gene: 238896411

Following gene: 238896418

Centisome position: 83.69

GC content: 64.73

Gene sequence:

>1449_bases
ATGATGATCCTTCCTTTCTCCGCGCGCCTGCGCGGCACTCTTTTTACCCTGACGCTGACGCTGCTCAGCGGCTGCGCGCT
GATCCAGGATGAGCCTGCCCAGGTCGCCATCGTCAATCCGCAGCAGGCCCAGCTGGCGCAGGTGATCCACCTGGCGAACA
GCGACTGGCCGGCCGCCCGCTGGTGGGAGGCCTATGATGATCCTCAGCTCAATATGCTGATCAACCGGGCGCTGCAGAAC
TCGCCGACCATGCAGGCCGCCCGGCTGCGCATCTCCCAGTCGCAGTCCACGGTGGAACTCGCCCGGTCGGCGATGGGCCT
GCAGGCCACCGCCGTCGCGGCGCAAAACCGCCTGCGGATCACCGACAAATCCTTTAGCTGGCCCTACTCATACTCCCTGC
CGGTGGATAAAAACGGCCCCTGGTATACGCTGAATACCGTTGGCGTCGGGGCGCAGCTGAATATCGATCTCTGGGGGGCC
GATCGCGCCCGGGTCGCCGCCGCTATTGGCGAGAAAAACGCCCGGCTGGCGGAGACCGCCGGCATTGAGCTCGACATCGC
CAGCAGCGTGGCGCAGCTCTATTTCGCCATGCAGGCGACGTTCCAGAAAATCGCGCTGCTGCAGGAGCTGGAGGGCATTG
CCCGATTCTCGGTGGAAGCCCACGAGCACCGGACCCGGCGCGGCCTGGAAGACAGTGTGGATGTGGCCAACGCCCAGGCC
GAACAGCTCGCCGCTCGCCAGCAGATCATTAGCGCCGAGGGGATGCTGACCCAGTATCGTGAAACCCTGCGGGCGCTGAT
CGGCGCCGATGCGCAGAGCATGCCGGCCATCCATCCGGTGGCGCTGCCGGCGCTCCAGGAGACGCTGCCGCCGTCGCTCT
CTTTCGAGCTGCTGGCCCGCCGTCCGGACCTGCAGGCGCTGCGCGGCTACGTCACCGCCTCCCTGAGCCAGGTCGATGCG
GCGAAAGCGGCCTTCTACCCCCATTTTGATATCAAAGCGTTCTGGGGCTATAACGCCCTGAGCGTCGGGGATCTGTTTAA
GTCCTCTTTCCAGCAGATCAACCTGCTGCCCGGGCTGTATCTGCCGATCTTCGACGGCGGCCGTCTGAACGCTAATCTGC
AGTCGGTACGCACCGCCAGCAACATCCTGATCAAACAGTACAACCAGGCGGTGCTGGATGCGGTTCGCGATGTCGCCATC
AGCTCCAGCCAGCTTAACGACCTGAATCAGCAGCGCGCGCTGCAGCAGCTAAAAGTCACCGCGGCGCAGACCACCACCGA
TAGCGCTCGCGCCCATTATCAGCGCGGCCTCCTCAGCCGCTACGCCGCCGAAGAAGCCCGCCGGGCGGTCCTCGCCCAGC
AGCTGTTGCTGCTGGACATTGAGGCCCAGCGGCTAAGCACCGACATTACCCTGATCAAAGCCCTGGGCGGCGGCTATCGA
GGGCAGTAA

Upstream 100 bases:

>100_bases
ACCTGACTAACCCCTTTGGCCCGGCGCTGGCCGCCGCGCTGGCCGCCCTGCCCGACTGGGGGCCGACACCGATAGCGACT
GAGCAACAGGCTAAAACGTC

Downstream 100 bases:

>100_bases
CAAAAATGCCTTCCCCGAGGGGAAGGCAATCAGACTGCAGACAAAGTGCAATCTTCAGCGCTTGCCCGGCGGCGCTGCGC
TTGCGCGGGCCTACAGCTAA

Product: putative outer membrane efflux protein MdtP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MMILPFSARLRGTLFTLTLTLLSGCALIQDEPAQVAIVNPQQAQLAQVIHLANSDWPAARWWEAYDDPQLNMLINRALQN
SPTMQAARLRISQSQSTVELARSAMGLQATAVAAQNRLRITDKSFSWPYSYSLPVDKNGPWYTLNTVGVGAQLNIDLWGA
DRARVAAAIGEKNARLAETAGIELDIASSVAQLYFAMQATFQKIALLQELEGIARFSVEAHEHRTRRGLEDSVDVANAQA
EQLAARQQIISAEGMLTQYRETLRALIGADAQSMPAIHPVALPALQETLPPSLSFELLARRPDLQALRGYVTASLSQVDA
AKAAFYPHFDIKAFWGYNALSVGDLFKSSFQQINLLPGLYLPIFDGGRLNANLQSVRTASNILIKQYNQAVLDAVRDVAI
SSSQLNDLNQQRALQQLKVTAAQTTTDSARAHYQRGLLSRYAAEEARRAVLAQQLLLLDIEAQRLSTDITLIKALGGGYR
GQ

Sequences:

>Translated_482_residues
MMILPFSARLRGTLFTLTLTLLSGCALIQDEPAQVAIVNPQQAQLAQVIHLANSDWPAARWWEAYDDPQLNMLINRALQN
SPTMQAARLRISQSQSTVELARSAMGLQATAVAAQNRLRITDKSFSWPYSYSLPVDKNGPWYTLNTVGVGAQLNIDLWGA
DRARVAAAIGEKNARLAETAGIELDIASSVAQLYFAMQATFQKIALLQELEGIARFSVEAHEHRTRRGLEDSVDVANAQA
EQLAARQQIISAEGMLTQYRETLRALIGADAQSMPAIHPVALPALQETLPPSLSFELLARRPDLQALRGYVTASLSQVDA
AKAAFYPHFDIKAFWGYNALSVGDLFKSSFQQINLLPGLYLPIFDGGRLNANLQSVRTASNILIKQYNQAVLDAVRDVAI
SSSQLNDLNQQRALQQLKVTAAQTTTDSARAHYQRGLLSRYAAEEARRAVLAQQLLLLDIEAQRLSTDITLIKALGGGYR
GQ
>Mature_482_residues
MMILPFSARLRGTLFTLTLTLLSGCALIQDEPAQVAIVNPQQAQLAQVIHLANSDWPAARWWEAYDDPQLNMLINRALQN
SPTMQAARLRISQSQSTVELARSAMGLQATAVAAQNRLRITDKSFSWPYSYSLPVDKNGPWYTLNTVGVGAQLNIDLWGA
DRARVAAAIGEKNARLAETAGIELDIASSVAQLYFAMQATFQKIALLQELEGIARFSVEAHEHRTRRGLEDSVDVANAQA
EQLAARQQIISAEGMLTQYRETLRALIGADAQSMPAIHPVALPALQETLPPSLSFELLARRPDLQALRGYVTASLSQVDA
AKAAFYPHFDIKAFWGYNALSVGDLFKSSFQQINLLPGLYLPIFDGGRLNANLQSVRTASNILIKQYNQAVLDAVRDVAI
SSSQLNDLNQQRALQQLKVTAAQTTTDSARAHYQRGLLSRYAAEEARRAVLAQQLLLLDIEAQRLSTDITLIKALGGGYR
GQ

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI2367348, Length=462, Percent_Identity=49.7835497835498, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1786785, Length=462, Percent_Identity=26.6233766233766, Blast_Score=128, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 52893; Mature: 52893

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMILPFSARLRGTLFTLTLTLLSGCALIQDEPAQVAIVNPQQAQLAQVIHLANSDWPAAR
CEECCCCHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECCCHHHHHHHHHHCCCCCCCHH
WWEAYDDPQLNMLINRALQNSPTMQAARLRISQSQSTVELARSAMGLQATAVAAQNRLRI
HHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHCCCEEE
TDKSFSWPYSYSLPVDKNGPWYTLNTVGVGAQLNIDLWGADRARVAAAIGEKNARLAETA
ECCCCCCCEEEECCCCCCCCEEEEEEECCCEEEEEEEECCCHHHHHHHHCCCCCCHHHHC
GIELDIASSVAQLYFAMQATFQKIALLQELEGIARFSVEAHEHRTRRGLEDSVDVANAQA
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EQLAARQQIISAEGMLTQYRETLRALIGADAQSMPAIHPVALPALQETLPPSLSFELLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHC
RPDLQALRGYVTASLSQVDAAKAAFYPHFDIKAFWGYNALSVGDLFKSSFQQINLLPGLY
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCE
LPIFDGGRLNANLQSVRTASNILIKQYNQAVLDAVRDVAISSSQLNDLNQQRALQQLKVT
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
AAQTTTDSARAHYQRGLLSRYAAEEARRAVLAQQLLLLDIEAQRLSTDITLIKALGGGYR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC
GQ
CC
>Mature Secondary Structure
MMILPFSARLRGTLFTLTLTLLSGCALIQDEPAQVAIVNPQQAQLAQVIHLANSDWPAAR
CEECCCCHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECCCHHHHHHHHHHCCCCCCCHH
WWEAYDDPQLNMLINRALQNSPTMQAARLRISQSQSTVELARSAMGLQATAVAAQNRLRI
HHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHCCCEEE
TDKSFSWPYSYSLPVDKNGPWYTLNTVGVGAQLNIDLWGADRARVAAAIGEKNARLAETA
ECCCCCCCEEEECCCCCCCCEEEEEEECCCEEEEEEEECCCHHHHHHHHCCCCCCHHHHC
GIELDIASSVAQLYFAMQATFQKIALLQELEGIARFSVEAHEHRTRRGLEDSVDVANAQA
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EQLAARQQIISAEGMLTQYRETLRALIGADAQSMPAIHPVALPALQETLPPSLSFELLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHC
RPDLQALRGYVTASLSQVDAAKAAFYPHFDIKAFWGYNALSVGDLFKSSFQQINLLPGLY
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCE
LPIFDGGRLNANLQSVRTASNILIKQYNQAVLDAVRDVAISSSQLNDLNQQRALQQLKVT
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
AAQTTTDSARAHYQRGLLSRYAAEEARRAVLAQQLLLLDIEAQRLSTDITLIKALGGGYR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC
GQ
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]