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The map label for this gene is fimB [H]

Identifier: 238896396

GI number: 238896396

Start: 4378441

End: 4379046

Strand: Direct

Name: fimB [H]

Synonym: KP1_4567

Alternate gene names: 238896396

Gene position: 4378441-4379046 (Clockwise)

Preceding gene: 238896394

Following gene: 238896397

Centisome position: 83.42

GC content: 52.97

Gene sequence:

>606_bases
ATGACGAATAACGCCGACTTAAAAAAAAGGAACTTCCTGACTCAGAATGAAATTGAGTCTTTACTTAAAGCGGCCGATAC
CGGTCCTTATGCTGCACGTAATTATTGCCTGACGTTACTGTGCTTCATCCATGGTCTGCGCGCCAGCGAGATCTGTCGTC
TACGAATATCGGATATCGACCTTGCTGCCCGATGTGTTTACATCCATCGGCTTAAAAAAGGGTTTTCGACTACCCACCCG
TTGCTGGATAAAGAGATCTACGCCCTAAAGCGCTGGCTGGCCATTCGCAGCAGCTGGCCGCAGGCCGCCAGCGAATGGCT
GTTTCTCTCCCGCAAAGGTAATCCCCTTTCCCGCCAACAGTTTTATCAGATTATCGCGTCCTCAGGGGGACTGGCAGGGC
TGCCACTGGAGATCCACCCGCACATGCTGCGGCACTCCTGTGGCTTTGCGTTGGCGAATATGGGGATCGATACCCGCTTG
ATACAGGATTATCTCGGGCATCGCAATATCCGCCACACCGTCTGGTATACGGCCAGCAATGCGGGACGCTTCTATGGCAT
CTGGGACAATCCCCGTGACAAACAGCGATCGTCGCTGATCCAATAG

Upstream 100 bases:

>100_bases
TATCACCACGCTGTTTCAAAATAAAAAGGCAGTCAAATTTAACAATGACCTGACGCAGGCTCGGAAAACCAAAAATATGC
CTGCAATAAAAGGGAAAACC

Downstream 100 bases:

>100_bases
CCTTGACGCCACGGATGGCGTTGTATCGCGATCGGTCGACAAATTAAAATATTCATGATTATTAACCCTGCGTTAATTAG
GATTACTGTTCCCACAAGTT

Product: tyrosine recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MTNNADLKKRNFLTQNEIESLLKAADTGPYAARNYCLTLLCFIHGLRASEICRLRISDIDLAARCVYIHRLKKGFSTTHP
LLDKEIYALKRWLAIRSSWPQAASEWLFLSRKGNPLSRQQFYQIIASSGGLAGLPLEIHPHMLRHSCGFALANMGIDTRL
IQDYLGHRNIRHTVWYTASNAGRFYGIWDNPRDKQRSSLIQ

Sequences:

>Translated_201_residues
MTNNADLKKRNFLTQNEIESLLKAADTGPYAARNYCLTLLCFIHGLRASEICRLRISDIDLAARCVYIHRLKKGFSTTHP
LLDKEIYALKRWLAIRSSWPQAASEWLFLSRKGNPLSRQQFYQIIASSGGLAGLPLEIHPHMLRHSCGFALANMGIDTRL
IQDYLGHRNIRHTVWYTASNAGRFYGIWDNPRDKQRSSLIQ
>Mature_200_residues
TNNADLKKRNFLTQNEIESLLKAADTGPYAARNYCLTLLCFIHGLRASEICRLRISDIDLAARCVYIHRLKKGFSTTHPL
LDKEIYALKRWLAIRSSWPQAASEWLFLSRKGNPLSRQQFYQIIASSGGLAGLPLEIHPHMLRHSCGFALANMGIDTRLI
QDYLGHRNIRHTVWYTASNAGRFYGIWDNPRDKQRSSLIQ

Specific function: FimB is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimB switches f

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1790767, Length=200, Percent_Identity=83, Blast_Score=356, Evalue=1e-100,
Organism=Escherichia coli, GI1790768, Length=184, Percent_Identity=52.1739130434783, Blast_Score=198, Evalue=2e-52,
Organism=Escherichia coli, GI1789261, Length=177, Percent_Identity=31.0734463276836, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790244, Length=183, Percent_Identity=28.4153005464481, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 23044; Mature: 22913

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNNADLKKRNFLTQNEIESLLKAADTGPYAARNYCLTLLCFIHGLRASEICRLRISDID
CCCCCCCHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHEEEECCHH
LAARCVYIHRLKKGFSTTHPLLDKEIYALKRWLAIRSSWPQAASEWLFLSRKGNPLSRQQ
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHEEEEECCCCCCHHHH
FYQIIASSGGLAGLPLEIHPHMLRHSCGFALANMGIDTRLIQDYLGHRNIRHTVWYTASN
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEECC
AGRFYGIWDNPRDKQRSSLIQ
CCEEEEECCCCCHHHHHHCCC
>Mature Secondary Structure 
TNNADLKKRNFLTQNEIESLLKAADTGPYAARNYCLTLLCFIHGLRASEICRLRISDID
CCCCCCHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHEEEECCHH
LAARCVYIHRLKKGFSTTHPLLDKEIYALKRWLAIRSSWPQAASEWLFLSRKGNPLSRQQ
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHEEEEECCCCCCHHHH
FYQIIASSGGLAGLPLEIHPHMLRHSCGFALANMGIDTRLIQDYLGHRNIRHTVWYTASN
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEECC
AGRFYGIWDNPRDKQRSSLIQ
CCEEEEECCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]