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The map label for this gene is ybbS [H]

Identifier: 238896379

GI number: 238896379

Start: 4361883

End: 4362752

Strand: Reverse

Name: ybbS [H]

Synonym: KP1_4546

Alternate gene names: 238896379

Gene position: 4362752-4361883 (Counterclockwise)

Preceding gene: 238896386

Following gene: 238896378

Centisome position: 83.12

GC content: 64.25

Gene sequence:

>870_bases
ATGCGTTATTCACCGGAAGCCTTAACCGCCTTTGTCGAGGCGGTCGACAGCGGATCGTTCTCCGCCGCCGCCCGCCGCCT
GCGGAAAAGTCAGTCGACGATCAGTACCGCCATCGCCAATCTGGAGGCCGATCTCGGTGTAATCCTCTTTGACAGGGCAA
CGCGGCAACCGACGCTGACCCCGCAGGGGGAGCAGGTGCTGAGCTATGTCAAAGCGATTCTTGCCGCCAGCGAGCGGCTG
GACGAACTGGCTGTGTCGCTGTCCGGCGAGACGGAGCCGCGGCTGACCTTCGTGCTCTCCGATACTCTGCACCCGGACGT
GCTGGAAGATCTGCTGGTGCAGTTTGACCGCCGCTTTCCTCATACCGAGTTTGAGTGTTTGATTGGCGAAGACGAGGATG
TGATCGATCTCTTGCAAAAATCCCGCGCCCAGGTGGGGCTGATTGAGGCGAGGGAGCGCTACCCCACCGATATCGGCAGC
ACCCGCCTGCCGCTGCAGACGGCGATGGGCATTTATGTAGCCCCTGGCCATCCGCTGGCGGCGCAGGGTAAGGTCGCCTG
GGATGAGCTGCGCAGCTGGCGCGAGCTGCGTTTGAGCACCTTTCTGGCCAGCGCCACCGAACCTGCCGCAGGCCAGGTCT
GGTCGGCGCCAAACTACCTGCTGCTGCTCAGCATGGCGGCGCAGGGGTTCGGCTGGTGCATTCTGCCCAGCGCGCTGGTG
GCGGAGTTTGCGCCGCAGGGCGGGCTGGTGGCGCTCGATATCCCCGGCTGGCCGCGGGCGATTTCAGTCGATCTGCTGTG
GAATAAGAAAGCGCCGCCGGGAGCGGCCGGCAGCTGGCTGCGTCAGCATCTGCAGCGGCGTGAACGTTAA

Upstream 100 bases:

>100_bases
CGAGCTACCTCCAGTTTTAGCCTGAACAGGAAATTACCCGGCAGTTTATGGAAAAATATGATAAACAAAAGATAGGACCC
ATCGATATTGTAGATACATC

Downstream 100 bases:

>100_bases
CGAATAGCTATTTCTTTGTGATTGGCTTCACTTTTTTTAAACAATTACAAAGTTTTTTGATAACAATTATCTAGTATATC
GCTGTTTCTTTGCGCAAATG

Product: putative LysR-family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MRYSPEALTAFVEAVDSGSFSAAARRLRKSQSTISTAIANLEADLGVILFDRATRQPTLTPQGEQVLSYVKAILAASERL
DELAVSLSGETEPRLTFVLSDTLHPDVLEDLLVQFDRRFPHTEFECLIGEDEDVIDLLQKSRAQVGLIEARERYPTDIGS
TRLPLQTAMGIYVAPGHPLAAQGKVAWDELRSWRELRLSTFLASATEPAAGQVWSAPNYLLLLSMAAQGFGWCILPSALV
AEFAPQGGLVALDIPGWPRAISVDLLWNKKAPPGAAGSWLRQHLQRRER

Sequences:

>Translated_289_residues
MRYSPEALTAFVEAVDSGSFSAAARRLRKSQSTISTAIANLEADLGVILFDRATRQPTLTPQGEQVLSYVKAILAASERL
DELAVSLSGETEPRLTFVLSDTLHPDVLEDLLVQFDRRFPHTEFECLIGEDEDVIDLLQKSRAQVGLIEARERYPTDIGS
TRLPLQTAMGIYVAPGHPLAAQGKVAWDELRSWRELRLSTFLASATEPAAGQVWSAPNYLLLLSMAAQGFGWCILPSALV
AEFAPQGGLVALDIPGWPRAISVDLLWNKKAPPGAAGSWLRQHLQRRER
>Mature_289_residues
MRYSPEALTAFVEAVDSGSFSAAARRLRKSQSTISTAIANLEADLGVILFDRATRQPTLTPQGEQVLSYVKAILAASERL
DELAVSLSGETEPRLTFVLSDTLHPDVLEDLLVQFDRRFPHTEFECLIGEDEDVIDLLQKSRAQVGLIEARERYPTDIGS
TRLPLQTAMGIYVAPGHPLAAQGKVAWDELRSWRELRLSTFLASATEPAAGQVWSAPNYLLLLSMAAQGFGWCILPSALV
AEFAPQGGLVALDIPGWPRAISVDLLWNKKAPPGAAGSWLRQHLQRRER

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786713, Length=125, Percent_Identity=36, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786401, Length=146, Percent_Identity=34.9315068493151, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788481, Length=191, Percent_Identity=27.7486910994764, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786508, Length=299, Percent_Identity=25.752508361204, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790262, Length=252, Percent_Identity=26.984126984127, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87082024, Length=272, Percent_Identity=25.3676470588235, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31744; Mature: 31744

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYSPEALTAFVEAVDSGSFSAAARRLRKSQSTISTAIANLEADLGVILFDRATRQPTLT
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCC
PQGEQVLSYVKAILAASERLDELAVSLSGETEPRLTFVLSDTLHPDVLEDLLVQFDRRFP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCC
HTEFECLIGEDEDVIDLLQKSRAQVGLIEARERYPTDIGSTRLPLQTAMGIYVAPGHPLA
CCCEEEEECCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHCEEEECCCCCCC
AQGKVAWDELRSWRELRLSTFLASATEPAAGQVWSAPNYLLLLSMAAQGFGWCILPSALV
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHH
AEFAPQGGLVALDIPGWPRAISVDLLWNKKAPPGAAGSWLRQHLQRRER
HHHCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRYSPEALTAFVEAVDSGSFSAAARRLRKSQSTISTAIANLEADLGVILFDRATRQPTLT
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCC
PQGEQVLSYVKAILAASERLDELAVSLSGETEPRLTFVLSDTLHPDVLEDLLVQFDRRFP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCC
HTEFECLIGEDEDVIDLLQKSRAQVGLIEARERYPTDIGSTRLPLQTAMGIYVAPGHPLA
CCCEEEEECCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHCEEEECCCCCCC
AQGKVAWDELRSWRELRLSTFLASATEPAAGQVWSAPNYLLLLSMAAQGFGWCILPSALV
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHH
AEFAPQGGLVALDIPGWPRAISVDLLWNKKAPPGAAGSWLRQHLQRRER
HHHCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]