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The map label for this gene is licC [H]

Identifier: 238896359

GI number: 238896359

Start: 4339131

End: 4340483

Strand: Reverse

Name: licC [H]

Synonym: KP1_4524

Alternate gene names: 238896359

Gene position: 4340483-4339131 (Counterclockwise)

Preceding gene: 238896361

Following gene: 238896358

Centisome position: 82.7

GC content: 57.72

Gene sequence:

>1353_bases
CTGAGGTACTCTTTTATGGCATTACAGGACAAACTGATCGACGCGCTGGGGCGTTTCGCGACGACATTCAACAGCTATCG
CTACATTATGGCGATCAAATCGGCGTTTATTACCCTGATGCCGGTGATCATCGTCGGGGCCTTTTCGGTGCTGATCTCCA
ATATGGTGCTGGATCCGAAGAATGGGCTCGCCAGCTTTTCCTCGCTCTCCTTTCTTGCGGCGCTGAAGCCGATCACCAGC
GCGCTAAACTACGCTACGCTCAACTTCCTCAATATCGGCGCCGTGTTTCTGATCGGTATTGAGCTGGGGCGGATCAACGG
CATCAAAAGCCTGTTTCCCGGCCTGTTGGCGGTGATCTGCTTTATCTGCGTCACGCCGACCACGGTAGAGATGATGGTCG
ATGGCCAGATGCACGTGGTGAAAGATGTCCTGCTGCGCCAGTTTTCCGATACCCGCAGTCTGTTCCTTGGGATGTTCATC
GCCATTCTGTCAGTGGAGATTTACTGCTGGCTGGAAGGGCGCAAGGGACTGAAGATCAAAATGCCGGATACCGTGCCGCC
GAACGTCTCTGCCTCTTTTTCCGCGCTGATCCCGGCGATCATCACCACCACCGCGATCGCCACCTTTGGTTTTCTCTTTC
ACCAGCTGACGGGAATGTATCTCTACGATGCGGTCTACCAGGTGGTGCAGCAGCCGCTGGAGCGGGTGGTGCAGAGCCTG
CCGGGGATCCTGCTGCTGATGTTCGTCGCCCAGCTGTTCTGGGTGATCGGCATTCACGGCAACCAGATGATCAAGCCGAT
CCGCGAGCCGCTGCTGCTGGGAGCGATCACCGTCAATATGAGCGCTTTTGAGCAGGGGAAAGAGGTACCGAACATCATCA
CGATGCCCTTCTGGGATGTCTACATGAGCATCGGCGGCTCGGGGCTGACCATCGGCCTGCTGATTGCGGTGATGATCGCC
ACCAGGCGCAAAGAGATGAAAGAGATCGCCAAGCTGTCGATAGGCCCGGGGCTGTTCAATATTAACGAGCCGGTGATCTT
CGGGATGCCGATCATGCTTAACCCGATCCTCGCCATCCCGTTTATCATCACCCCGCTGGTGACCGGCAGCATCGGCTATT
TCGCCACCCTGACCGGCTTCGCCGGCAAGGCGGTGGTGATGGTCCCCTGGACCACGCCGCCGCTGATCAACGCCTGGCTC
TCCACCGCCGGCTCGATGGGGGCGGTGGTGACCCAGCTTATCTGCATCGTCGTCGCAGTGCTTATCTATCTGCCTTTCGT
CAAAATCGCCTCCCGCCGTGCCGATGCCGCGCAGCGTCAGGTAGACAATCAACAAACCGCCAACCCTGTCTGA

Upstream 100 bases:

>100_bases
GCGTTGCGAGCGCTGTCACAGAACTATTTTTGCCTGGCGACTATGTTTTGGTATGCCAAAAGTCTCTGGCTGTTCACCTG
GCCGCAATAAGCCCTTTACA

Downstream 100 bases:

>100_bases
GGAGCCTATGACTACCGTACGGATGACAATTCCCGATGATTTTATCCTTGGCGCGGCGGCTTCCGCCTGGCAGACCGAAG
GCTGGAGCGGGAAAAAACCA

Product: putative PTS family enzyme IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MRYSFMALQDKLIDALGRFATTFNSYRYIMAIKSAFITLMPVIIVGAFSVLISNMVLDPKNGLASFSSLSFLAALKPITS
ALNYATLNFLNIGAVFLIGIELGRINGIKSLFPGLLAVICFICVTPTTVEMMVDGQMHVVKDVLLRQFSDTRSLFLGMFI
AILSVEIYCWLEGRKGLKIKMPDTVPPNVSASFSALIPAIITTTAIATFGFLFHQLTGMYLYDAVYQVVQQPLERVVQSL
PGILLLMFVAQLFWVIGIHGNQMIKPIREPLLLGAITVNMSAFEQGKEVPNIITMPFWDVYMSIGGSGLTIGLLIAVMIA
TRRKEMKEIAKLSIGPGLFNINEPVIFGMPIMLNPILAIPFIITPLVTGSIGYFATLTGFAGKAVVMVPWTTPPLINAWL
STAGSMGAVVTQLICIVVAVLIYLPFVKIASRRADAAQRQVDNQQTANPV

Sequences:

>Translated_450_residues
MRYSFMALQDKLIDALGRFATTFNSYRYIMAIKSAFITLMPVIIVGAFSVLISNMVLDPKNGLASFSSLSFLAALKPITS
ALNYATLNFLNIGAVFLIGIELGRINGIKSLFPGLLAVICFICVTPTTVEMMVDGQMHVVKDVLLRQFSDTRSLFLGMFI
AILSVEIYCWLEGRKGLKIKMPDTVPPNVSASFSALIPAIITTTAIATFGFLFHQLTGMYLYDAVYQVVQQPLERVVQSL
PGILLLMFVAQLFWVIGIHGNQMIKPIREPLLLGAITVNMSAFEQGKEVPNIITMPFWDVYMSIGGSGLTIGLLIAVMIA
TRRKEMKEIAKLSIGPGLFNINEPVIFGMPIMLNPILAIPFIITPLVTGSIGYFATLTGFAGKAVVMVPWTTPPLINAWL
STAGSMGAVVTQLICIVVAVLIYLPFVKIASRRADAAQRQVDNQQTANPV
>Mature_450_residues
MRYSFMALQDKLIDALGRFATTFNSYRYIMAIKSAFITLMPVIIVGAFSVLISNMVLDPKNGLASFSSLSFLAALKPITS
ALNYATLNFLNIGAVFLIGIELGRINGIKSLFPGLLAVICFICVTPTTVEMMVDGQMHVVKDVLLRQFSDTRSLFLGMFI
AILSVEIYCWLEGRKGLKIKMPDTVPPNVSASFSALIPAIITTTAIATFGFLFHQLTGMYLYDAVYQVVQQPLERVVQSL
PGILLLMFVAQLFWVIGIHGNQMIKPIREPLLLGAITVNMSAFEQGKEVPNIITMPFWDVYMSIGGSGLTIGLLIAVMIA
TRRKEMKEIAKLSIGPGLFNINEPVIFGMPIMLNPILAIPFIITPLVTGSIGYFATLTGFAGKAVVMVPWTTPPLINAWL
STAGSMGAVVTQLICIVVAVLIYLPFVKIASRRADAAQRQVDNQQTANPV

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=456, Percent_Identity=31.5789473684211, Blast_Score=204, Evalue=7e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 49116; Mature: 49116

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYSFMALQDKLIDALGRFATTFNSYRYIMAIKSAFITLMPVIIVGAFSVLISNMVLDPK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NGLASFSSLSFLAALKPITSALNYATLNFLNIGAVFLIGIELGRINGIKSLFPGLLAVIC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FICVTPTTVEMMVDGQMHVVKDVLLRQFSDTRSLFLGMFIAILSVEIYCWLEGRKGLKIK
HHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEE
MPDTVPPNVSASFSALIPAIITTTAIATFGFLFHQLTGMYLYDAVYQVVQQPLERVVQSL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PGILLLMFVAQLFWVIGIHGNQMIKPIREPLLLGAITVNMSAFEQGKEVPNIITMPFWDV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEECHHHHH
YMSIGGSGLTIGLLIAVMIATRRKEMKEIAKLSIGPGLFNINEPVIFGMPIMLNPILAIP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEECCHHHHHHHHHHH
FIITPLVTGSIGYFATLTGFAGKAVVMVPWTTPPLINAWLSTAGSMGAVVTQLICIVVAV
HHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
LIYLPFVKIASRRADAAQRQVDNQQTANPV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRYSFMALQDKLIDALGRFATTFNSYRYIMAIKSAFITLMPVIIVGAFSVLISNMVLDPK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NGLASFSSLSFLAALKPITSALNYATLNFLNIGAVFLIGIELGRINGIKSLFPGLLAVIC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FICVTPTTVEMMVDGQMHVVKDVLLRQFSDTRSLFLGMFIAILSVEIYCWLEGRKGLKIK
HHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEE
MPDTVPPNVSASFSALIPAIITTTAIATFGFLFHQLTGMYLYDAVYQVVQQPLERVVQSL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PGILLLMFVAQLFWVIGIHGNQMIKPIREPLLLGAITVNMSAFEQGKEVPNIITMPFWDV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEECHHHHH
YMSIGGSGLTIGLLIAVMIATRRKEMKEIAKLSIGPGLFNINEPVIFGMPIMLNPILAIP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEECCHHHHHHHHHHH
FIITPLVTGSIGYFATLTGFAGKAVVMVPWTTPPLINAWLSTAGSMGAVVTQLICIVVAV
HHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
LIYLPFVKIASRRADAAQRQVDNQQTANPV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]