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The map label for this gene is recD [H]

Identifier: 238896334

GI number: 238896334

Start: 4309089

End: 4310933

Strand: Reverse

Name: recD [H]

Synonym: KP1_4497

Alternate gene names: 238896334

Gene position: 4310933-4309089 (Counterclockwise)

Preceding gene: 238896335

Following gene: 238896331

Centisome position: 82.14

GC content: 67.91

Gene sequence:

>1845_bases
ATGACTTTCGAACAACTACTGCTGGCGGCGGTGGAGCAGCGTCTGCTGCGGCCGCTGGACGTCCAGTTTGCCCTGATGGT
GGCGCAAAACGACCCGCCGGCGGTCAAGCTGGCGGCGGCCTTGCTGAGCCGGGATGCCGGCGAGGGGCACGTCTGTCTGC
CGCTCTCGCGGTTGAGCGGCGACGAGGCGCTGAGCGGTAAAGCCGGGGAGATCCGCGATCGGCTGCTGGCCGAAGCCGGC
GCGCCGGAGGACTGGCCCGCACTGCTGCTCGCTTCGTCGGCGGTGAGCTGCGGTGATGCTCCGGCGCCGATGATTTTGTG
CGGCGACCGGCTCTATCTCAACCGGATGTGGCGCAACGAGCTGACCGTCGCCCGCTTCTTCAATGAAGCCAACCGGGTGC
TGGAGATGGATGAGGCCCGGCTGGCGTCAACCCTGAATGCCCTGTTCCCTGCCACCGGCGAAACCGACTGGCAAAAAGTG
GCCGCGGCGGTGGCGCTGACCCGCCGCATCTCAGTGATCTCCGGCGGTCCCGGGACCGGGAAGACCACCACCGTGGCGAA
GCTTCTGGCGGCGCTGATCCAGATCGAAGATAGTCCGCGCTGTCGTATTCGCCTGGCGGCGCCAACCGGGAAAGCGGCGG
CGCGTCTGACCGAATCGCTGGGCGCGGCGCTGAGAAAATTGCCGCTGACCGACGCGCAGAAAGCGTTGATTCCCACCGAG
GCCAGCACGCTGCATCGTCTGCTGGGCGCCCAGCCAGGCAGCCAGCGGATGCGCTATCACGCCGGCAACCCGCTGCATCT
GGACGTGCTGGTGGTGGATGAAGCCTCGATGATCGACCTGCCGATGATGTCGCGGCTTATCGACGCGCTGCCGGCCCACG
GGCGGGTGATTTTCCTCGGCGATCGCGACCAGCTGGCCTCCGTAGAAGCGGGGGCGGTGCTGGGGGATATCTGCGCCTGG
GCGAGTTCGGGCTATACCGCCGCGCGGGCGCAGGAGCTGACCCGGCTGACCGGTTCGCCGGTGCCGGCGGGCGAGGGGGC
TATCGCGGGCGCGCTGAGAGACAGTTTGTGCCTGCTGCAAAAGAGCTATCGCTTCGGTAGTCACTCCGGCATCGGGAGCC
TGGCGCGGGCGGTGAACGCTGGCGCGCGCGCGGAGGTGAAGGCCACGCTGCGCCAGCCGTTTGACGATATCGCGCTTCAT
CCCCTCAGCACGACCGAAGAGTACGAAGCCATGCTCGGCGCGGCTCAGCAGGGCTATGAGCGCTACCTGCAGCTGCGCCG
CGAGCGGGCCGAACCGCAGGCCATGCTGGCCGCTTTCAGCGAATTCCAGCTGCTGTGCGCGCTGCGCGAGGGGCCGTACG
GCGTGAGCGGCGTCAATGAGCGGCTGGAGCAGCGGCTCAACCGCCAGCGGGCGATCGCCCTACCGCGCCACTCTCGCTGG
TATGACGGCCGACCGATCATGATATCGCGCAACGACAGCGCGCTGGGGCTGTTTAACGGCGATATCGGCATCGCCCTGGA
GCGCAACGGCGAGCTGCGGGTGTGGTTCCTGATGCCCGACGGCGCCATCAAGTCGGTGCAGCCGAGCCGTCTGCCGGAGC
ATGATACCGCCTGGGCGATGACCGTGCATAAATCGCAGGGCTCGGAGTTCGAACACGCGGCGCTGATCCTGCCGGCGCGC
AGCGTCCCGCTGGTGACCCGCGAACTGGTCTACACGGCGATCACCCGCGCGAAACGGCGGTTGTCGCTCTATGCCGACGA
GCAGGTGCTCTCCCAGGCCATTGTGACGCGCACCGAACGGCGCAGCGGCCTGGCGGAGATTTTCGCCGGGCGCGAAGCCC
CCTGA

Upstream 100 bases:

>100_bases
GGCAGGAGGGGGGGCAGGGGATCTTCACCACCCGGCCGGTGCGACCGCTGATTGACGGTCTGGATCAGCTTTTTGCCGGA
GAAACTCAGGAGGAGGCCTC

Downstream 100 bases:

>100_bases
GACGCCGGGTCCGGGCGATGGAAAATGCTGCAGCCGTCGCCCGGGCTGGCGGAAAAATCAGTAACTAAAGAACAGAGGGA
TAAGCCAGAGCGCCGAGATC

Product: exonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 614; Mature: 613

Protein sequence:

>614_residues
MTFEQLLLAAVEQRLLRPLDVQFALMVAQNDPPAVKLAAALLSRDAGEGHVCLPLSRLSGDEALSGKAGEIRDRLLAEAG
APEDWPALLLASSAVSCGDAPAPMILCGDRLYLNRMWRNELTVARFFNEANRVLEMDEARLASTLNALFPATGETDWQKV
AAAVALTRRISVISGGPGTGKTTTVAKLLAALIQIEDSPRCRIRLAAPTGKAAARLTESLGAALRKLPLTDAQKALIPTE
ASTLHRLLGAQPGSQRMRYHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPAHGRVIFLGDRDQLASVEAGAVLGDICAW
ASSGYTAARAQELTRLTGSPVPAGEGAIAGALRDSLCLLQKSYRFGSHSGIGSLARAVNAGARAEVKATLRQPFDDIALH
PLSTTEEYEAMLGAAQQGYERYLQLRRERAEPQAMLAAFSEFQLLCALREGPYGVSGVNERLEQRLNRQRAIALPRHSRW
YDGRPIMISRNDSALGLFNGDIGIALERNGELRVWFLMPDGAIKSVQPSRLPEHDTAWAMTVHKSQGSEFEHAALILPAR
SVPLVTRELVYTAITRAKRRLSLYADEQVLSQAIVTRTERRSGLAEIFAGREAP

Sequences:

>Translated_614_residues
MTFEQLLLAAVEQRLLRPLDVQFALMVAQNDPPAVKLAAALLSRDAGEGHVCLPLSRLSGDEALSGKAGEIRDRLLAEAG
APEDWPALLLASSAVSCGDAPAPMILCGDRLYLNRMWRNELTVARFFNEANRVLEMDEARLASTLNALFPATGETDWQKV
AAAVALTRRISVISGGPGTGKTTTVAKLLAALIQIEDSPRCRIRLAAPTGKAAARLTESLGAALRKLPLTDAQKALIPTE
ASTLHRLLGAQPGSQRMRYHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPAHGRVIFLGDRDQLASVEAGAVLGDICAW
ASSGYTAARAQELTRLTGSPVPAGEGAIAGALRDSLCLLQKSYRFGSHSGIGSLARAVNAGARAEVKATLRQPFDDIALH
PLSTTEEYEAMLGAAQQGYERYLQLRRERAEPQAMLAAFSEFQLLCALREGPYGVSGVNERLEQRLNRQRAIALPRHSRW
YDGRPIMISRNDSALGLFNGDIGIALERNGELRVWFLMPDGAIKSVQPSRLPEHDTAWAMTVHKSQGSEFEHAALILPAR
SVPLVTRELVYTAITRAKRRLSLYADEQVLSQAIVTRTERRSGLAEIFAGREAP
>Mature_613_residues
TFEQLLLAAVEQRLLRPLDVQFALMVAQNDPPAVKLAAALLSRDAGEGHVCLPLSRLSGDEALSGKAGEIRDRLLAEAGA
PEDWPALLLASSAVSCGDAPAPMILCGDRLYLNRMWRNELTVARFFNEANRVLEMDEARLASTLNALFPATGETDWQKVA
AAVALTRRISVISGGPGTGKTTTVAKLLAALIQIEDSPRCRIRLAAPTGKAAARLTESLGAALRKLPLTDAQKALIPTEA
STLHRLLGAQPGSQRMRYHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPAHGRVIFLGDRDQLASVEAGAVLGDICAWA
SSGYTAARAQELTRLTGSPVPAGEGAIAGALRDSLCLLQKSYRFGSHSGIGSLARAVNAGARAEVKATLRQPFDDIALHP
LSTTEEYEAMLGAAQQGYERYLQLRRERAEPQAMLAAFSEFQLLCALREGPYGVSGVNERLEQRLNRQRAIALPRHSRWY
DGRPIMISRNDSALGLFNGDIGIALERNGELRVWFLMPDGAIKSVQPSRLPEHDTAWAMTVHKSQGSEFEHAALILPARS
VPLVTRELVYTAITRAKRRLSLYADEQVLSQAIVTRTERRSGLAEIFAGREAP

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=612, Percent_Identity=71.7320261437908, Blast_Score=853, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 66537; Mature: 66406

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFEQLLLAAVEQRLLRPLDVQFALMVAQNDPPAVKLAAALLSRDAGEGHVCLPLSRLSG
CCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEHHHCCC
DEALSGKAGEIRDRLLAEAGAPEDWPALLLASSAVSCGDAPAPMILCGDRLYLNRMWRNE
CHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHH
LTVARFFNEANRVLEMDEARLASTLNALFPATGETDWQKVAAAVALTRRISVISGGPGTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCC
KTTTVAKLLAALIQIEDSPRCRIRLAAPTGKAAARLTESLGAALRKLPLTDAQKALIPTE
CHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCC
ASTLHRLLGAQPGSQRMRYHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPAHGRVIFLG
HHHHHHHHCCCCCCHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEE
DRDQLASVEAGAVLGDICAWASSGYTAARAQELTRLTGSPVPAGEGAIAGALRDSLCLLQ
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
KSYRFGSHSGIGSLARAVNAGARAEVKATLRQPFDDIALHPLSTTEEYEAMLGAAQQGYE
HHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHH
RYLQLRRERAEPQAMLAAFSEFQLLCALREGPYGVSGVNERLEQRLNRQRAIALPRHSRW
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHEEECCCCCCC
YDGRPIMISRNDSALGLFNGDIGIALERNGELRVWFLMPDGAIKSVQPSRLPEHDTAWAM
CCCCEEEEECCCCEEEEEECCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEE
TVHKSQGSEFEHAALILPARSVPLVTRELVYTAITRAKRRLSLYADEQVLSQAIVTRTER
EEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSGLAEIFAGREAP
HCCHHHHHCCCCCC
>Mature Secondary Structure 
TFEQLLLAAVEQRLLRPLDVQFALMVAQNDPPAVKLAAALLSRDAGEGHVCLPLSRLSG
CHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEHHHCCC
DEALSGKAGEIRDRLLAEAGAPEDWPALLLASSAVSCGDAPAPMILCGDRLYLNRMWRNE
CHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHH
LTVARFFNEANRVLEMDEARLASTLNALFPATGETDWQKVAAAVALTRRISVISGGPGTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCC
KTTTVAKLLAALIQIEDSPRCRIRLAAPTGKAAARLTESLGAALRKLPLTDAQKALIPTE
CHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCC
ASTLHRLLGAQPGSQRMRYHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPAHGRVIFLG
HHHHHHHHCCCCCCHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEE
DRDQLASVEAGAVLGDICAWASSGYTAARAQELTRLTGSPVPAGEGAIAGALRDSLCLLQ
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
KSYRFGSHSGIGSLARAVNAGARAEVKATLRQPFDDIALHPLSTTEEYEAMLGAAQQGYE
HHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHH
RYLQLRRERAEPQAMLAAFSEFQLLCALREGPYGVSGVNERLEQRLNRQRAIALPRHSRW
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHEEECCCCCCC
YDGRPIMISRNDSALGLFNGDIGIALERNGELRVWFLMPDGAIKSVQPSRLPEHDTAWAM
CCCCEEEEECCCCEEEEEECCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEE
TVHKSQGSEFEHAALILPARSVPLVTRELVYTAITRAKRRLSLYADEQVLSQAIVTRTER
EEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSGLAEIFAGREAP
HCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]