Click here to switch to the map view.

The map label for this gene is cbiA [H]

Identifier: 238896304

GI number: 238896304

Start: 4283425

End: 4284879

Strand: Reverse

Name: cbiA [H]

Synonym: KP1_4466

Alternate gene names: 238896304

Gene position: 4284879-4283425 (Counterclockwise)

Preceding gene: 238896305

Following gene: 238896303

Centisome position: 81.64

GC content: 63.23

Gene sequence:

>1455_bases
GTGGGTGGCTTAGCGGTGCGTGGTCGCAGGACCAGGCATGCGCGTAGCTATACCCTGACCGCCAGAACAGGACAGGGTAT
GGCAACCAGGCGTGCGTTCATTCTTGCGGGTACCGGCAGCGGTTGTGGCAAAACCACCGTTACGCTCGGCCTGCTCAGCT
TGCTCCAACAGCGCGGTATGCGGGTGCAACCCTGTAAAGTCGGGCCTGACTACCTGGATACCGCCTGGCACACCGCCATC
AGTGGCATCGCTTCCCGCAATCTCGACAGCTTTATGCTTCCCGCCCCGATACTCAACGCGCTGTTTACCGAACAGCTACA
GCAGGCCGACATCGCGGTTATCGAAGGGGTGATGGGCCTGTATGACGGCTACGGCATCGACCCTAACTACTGCAGCAGCG
CGGCAATGGCTAAGCAGCTTGGCTGCCCGGTGATTTTGCTGGTGGATGGCAAAGCGGTGTCGACCTCCATCGCCGCCACG
GTGATGGGTTTTCAACATTTTGATCCGGCTCTCGACATCGCTGGCGTTATCGTCAATCGGGTCAACAGCGACGCGCACTT
CCAGCTGCTGAAAAGCGCCATTGAGCGCTACTGTCGGGTGCCAGTGCTCGGCTATGTGCCGCGCGTGGAAGGCGTGGCGC
TGCCCGAACGACATCTGGGGCTGGTGACCGCCCGCGAGTCGGTGGTCACTCAGCAGGCATGGTGGGATTTTGCCAGCCTG
CTGGGGCGCACCCTCGATATAGACCGGCTGCTGGCCCTCAGCGAACTGGCCGCCATGCCGATCGGCGAGTGGGGAGAACA
GCTTGCCGCCGATGCCGGCGAAGGACTGACGCTGGCCCTCGCCGACGATGAGGCCTTCAATTTTTATTACCCCGATAACC
TGGCGCTGCTGGCGCGCTGCGGCGTGAAGATGGTGCGCTTTAGCCCGCTGCGCGATCGCCAGCTGCCGGCCTGCCAGATG
ATCTGGCTCGGCGGCGGCTATCCGGAGCTGCATGCGGCCGGGCTATCCGCTAACCACGAGATGCTGACACAGCTTCGCGC
GGCGCACCGGCGCGGGGTGGCGATCTACGCCGAGTGCGGCGGCCTGATGTACCTGGGCACGACCCTGGAAGTCACCAGCG
GCGAGCGCTACACGATGGCGGATATTATTCCCGGACACAGCCGAATGGGGACGCGTCTGACCCGGTTCGGCTACTGCGAA
GCGCAGGCGCAGCAGCAGACGCTGCTGGCAGCCCCTGGCGAGTGGCTGCGCGGCCATGAATTTCATTACTCCGATTTTTC
TCCCGCCACTCCCGCCGTACTGGCCTGCCGTAAACAGCGAGACGGTAAGACGCTCCAGCAGTGGCAGGGAGGATGGCAGT
CCGGCAGCGCCTTTGCGAGCTATCTCCATGTCCATTTTGCCCAGCGCCCGACCATGCTCAACCACTGGCTGCAGGCAGCA
AGGAGGGCGCTATGA

Upstream 100 bases:

>100_bases
CCGCAAAAACCACTGATCGAAAGATTGGGAAGGGCGGGCGAGAACGAGGCTAAGCCAGAAGACCTGCCTGCCGGTAACTG
ACCAACAACTTCGGTGGGAA

Downstream 100 bases:

>100_bases
CCCTTCTCGCCTGGTGTGTAGCCTGGATACTTGATGTCGTCATTGGCGATCCGCCGCACTGGCCGCATCCGGTGCGCTGG
ATAGGTCGCCTGATCGCCGT

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MGGLAVRGRRTRHARSYTLTARTGQGMATRRAFILAGTGSGCGKTTVTLGLLSLLQQRGMRVQPCKVGPDYLDTAWHTAI
SGIASRNLDSFMLPAPILNALFTEQLQQADIAVIEGVMGLYDGYGIDPNYCSSAAMAKQLGCPVILLVDGKAVSTSIAAT
VMGFQHFDPALDIAGVIVNRVNSDAHFQLLKSAIERYCRVPVLGYVPRVEGVALPERHLGLVTARESVVTQQAWWDFASL
LGRTLDIDRLLALSELAAMPIGEWGEQLAADAGEGLTLALADDEAFNFYYPDNLALLARCGVKMVRFSPLRDRQLPACQM
IWLGGGYPELHAAGLSANHEMLTQLRAAHRRGVAIYAECGGLMYLGTTLEVTSGERYTMADIIPGHSRMGTRLTRFGYCE
AQAQQQTLLAAPGEWLRGHEFHYSDFSPATPAVLACRKQRDGKTLQQWQGGWQSGSAFASYLHVHFAQRPTMLNHWLQAA
RRAL

Sequences:

>Translated_484_residues
MGGLAVRGRRTRHARSYTLTARTGQGMATRRAFILAGTGSGCGKTTVTLGLLSLLQQRGMRVQPCKVGPDYLDTAWHTAI
SGIASRNLDSFMLPAPILNALFTEQLQQADIAVIEGVMGLYDGYGIDPNYCSSAAMAKQLGCPVILLVDGKAVSTSIAAT
VMGFQHFDPALDIAGVIVNRVNSDAHFQLLKSAIERYCRVPVLGYVPRVEGVALPERHLGLVTARESVVTQQAWWDFASL
LGRTLDIDRLLALSELAAMPIGEWGEQLAADAGEGLTLALADDEAFNFYYPDNLALLARCGVKMVRFSPLRDRQLPACQM
IWLGGGYPELHAAGLSANHEMLTQLRAAHRRGVAIYAECGGLMYLGTTLEVTSGERYTMADIIPGHSRMGTRLTRFGYCE
AQAQQQTLLAAPGEWLRGHEFHYSDFSPATPAVLACRKQRDGKTLQQWQGGWQSGSAFASYLHVHFAQRPTMLNHWLQAA
RRAL
>Mature_483_residues
GGLAVRGRRTRHARSYTLTARTGQGMATRRAFILAGTGSGCGKTTVTLGLLSLLQQRGMRVQPCKVGPDYLDTAWHTAIS
GIASRNLDSFMLPAPILNALFTEQLQQADIAVIEGVMGLYDGYGIDPNYCSSAAMAKQLGCPVILLVDGKAVSTSIAATV
MGFQHFDPALDIAGVIVNRVNSDAHFQLLKSAIERYCRVPVLGYVPRVEGVALPERHLGLVTARESVVTQQAWWDFASLL
GRTLDIDRLLALSELAAMPIGEWGEQLAADAGEGLTLALADDEAFNFYYPDNLALLARCGVKMVRFSPLRDRQLPACQMI
WLGGGYPELHAAGLSANHEMLTQLRAAHRRGVAIYAECGGLMYLGTTLEVTSGERYTMADIIPGHSRMGTRLTRFGYCEA
QAQQQTLLAAPGEWLRGHEFHYSDFSPATPAVLACRKQRDGKTLQQWQGGWQSGSAFASYLHVHFAQRPTMLNHWLQAAR
RAL

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 52794; Mature: 52663

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGLAVRGRRTRHARSYTLTARTGQGMATRRAFILAGTGSGCGKTTVTLGLLSLLQQRGM
CCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCC
RVQPCKVGPDYLDTAWHTAISGIASRNLDSFMLPAPILNALFTEQLQQADIAVIEGVMGL
EEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YDGYGIDPNYCSSAAMAKQLGCPVILLVDGKAVSTSIAATVMGFQHFDPALDIAGVIVNR
HCCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VNSDAHFQLLKSAIERYCRVPVLGYVPRVEGVALPERHLGLVTARESVVTQQAWWDFASL
CCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHCCCEEHHHHHHHHHHHHHHHHH
LGRTLDIDRLLALSELAAMPIGEWGEQLAADAGEGLTLALADDEAFNFYYPDNLALLARC
HCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCHHHHHHC
GVKMVRFSPLRDRQLPACQMIWLGGGYPELHAAGLSANHEMLTQLRAAHRRGVAIYAECG
CCEEEEECCCCCCCCCCEEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHCCEEEEEECC
GLMYLGTTLEVTSGERYTMADIIPGHSRMGTRLTRFGYCEAQAQQQTLLAAPGEWLRGHE
CEEEEEEEEEECCCCEEEEEECCCCCCHHCCHHHHCCCCHHHHHHHHHCCCCCHHHCCCC
FHYSDFSPATPAVLACRKQRDGKTLQQWQGGWQSGSAFASYLHVHFAQRPTMLNHWLQAA
CCCCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
RRAL
HHCC
>Mature Secondary Structure 
GGLAVRGRRTRHARSYTLTARTGQGMATRRAFILAGTGSGCGKTTVTLGLLSLLQQRGM
CCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCC
RVQPCKVGPDYLDTAWHTAISGIASRNLDSFMLPAPILNALFTEQLQQADIAVIEGVMGL
EEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YDGYGIDPNYCSSAAMAKQLGCPVILLVDGKAVSTSIAATVMGFQHFDPALDIAGVIVNR
HCCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VNSDAHFQLLKSAIERYCRVPVLGYVPRVEGVALPERHLGLVTARESVVTQQAWWDFASL
CCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHCCCEEHHHHHHHHHHHHHHHHH
LGRTLDIDRLLALSELAAMPIGEWGEQLAADAGEGLTLALADDEAFNFYYPDNLALLARC
HCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCHHHHHHC
GVKMVRFSPLRDRQLPACQMIWLGGGYPELHAAGLSANHEMLTQLRAAHRRGVAIYAECG
CCEEEEECCCCCCCCCCEEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHCCEEEEEECC
GLMYLGTTLEVTSGERYTMADIIPGHSRMGTRLTRFGYCEAQAQQQTLLAAPGEWLRGHE
CEEEEEEEEEECCCCEEEEEECCCCCCHHCCHHHHCCCCHHHHHHHHHCCCCCHHHCCCC
FHYSDFSPATPAVLACRKQRDGKTLQQWQGGWQSGSAFASYLHVHFAQRPTMLNHWLQAA
CCCCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
RRAL
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 1374146 [H]