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The map label for this gene is cbiC [H]

Identifier: 238896302

GI number: 238896302

Start: 4281823

End: 4282458

Strand: Reverse

Name: cbiC [H]

Synonym: KP1_4464

Alternate gene names: 238896302

Gene position: 4282458-4281823 (Counterclockwise)

Preceding gene: 238896303

Following gene: 238896301

Centisome position: 81.59

GC content: 64.15

Gene sequence:

>636_bases
ATGCAGTACATCCAACAACCGCAGGCGATCGAGGCGAAAAGCTTCGACATCATCAGCGAGATCATCGCCGAAACGCGACC
GGACTACCGTTTCGCCAGCCCGCTGCACGAGGCGATTATCAAGCGGGTGATCCACACCACCGCTGACTTCGACTGGCTGG
ATATTCTGTGGTTTTCTCCGGATGCCCTGATCGCGCTGAGTGAGGCCTTGAGCAGGCCCTGCACGCTGTATACCGATACC
ACCATGGCGCTGTCCGGGATCAACAAAACCCTGCTGGCCCGCTTTGGCGGCGAATGCCGCTGCTATATCAGCGACCCGCG
GGTGGTGCGCGAGGCGCAAAGCCGGGGGATGACCCGCTCGATGGCGGCGGTGGATATTGCGGTGCAGGAGCCCGGGGAGA
AAGTGTTCGTCTTCGGCAATGCGCCAACCGCGCTGTTTCGCCTGCTGGAACATCGCGAGACCGCCATCGGCGGCGTGGTG
GGGGTGCCGGTCGGGTTCGTCGGCGCGGCGGAGTCGAAAGCGGCGCTCAGCGAGAGCGGCCTGCCGGCCATCGCCGCGCT
CGGCCGCAAAGGGGGAAGCAACGTGGCGGCAGCGATTGTGAACGCTCTGCTTTACCACCTGCGGGAGGCGCAATGA

Upstream 100 bases:

>100_bases
TCCCGAACCATTCGATTAATGTGGGTGGCGTCAAGCCTGGCGCTGGCGCTGTTTATCGGCGTGCGCTACTGGCTGGTCGG
CGCGGCCTGAGGAGAACCTG

Downstream 100 bases:

>100_bases
GCGATCAGACCTTTGACGCCCCGGTGTGGCATCACGGCAAAGCGCTGCGCAAGGGCTACACCACCGGCTCCTGCGCCACA
GCGGCGGCAAAAGTGGCGGC

Product: cobalt-precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MQYIQQPQAIEAKSFDIISEIIAETRPDYRFASPLHEAIIKRVIHTTADFDWLDILWFSPDALIALSEALSRPCTLYTDT
TMALSGINKTLLARFGGECRCYISDPRVVREAQSRGMTRSMAAVDIAVQEPGEKVFVFGNAPTALFRLLEHRETAIGGVV
GVPVGFVGAAESKAALSESGLPAIAALGRKGGSNVAAAIVNALLYHLREAQ

Sequences:

>Translated_211_residues
MQYIQQPQAIEAKSFDIISEIIAETRPDYRFASPLHEAIIKRVIHTTADFDWLDILWFSPDALIALSEALSRPCTLYTDT
TMALSGINKTLLARFGGECRCYISDPRVVREAQSRGMTRSMAAVDIAVQEPGEKVFVFGNAPTALFRLLEHRETAIGGVV
GVPVGFVGAAESKAALSESGLPAIAALGRKGGSNVAAAIVNALLYHLREAQ
>Mature_211_residues
MQYIQQPQAIEAKSFDIISEIIAETRPDYRFASPLHEAIIKRVIHTTADFDWLDILWFSPDALIALSEALSRPCTLYTDT
TMALSGINKTLLARFGGECRCYISDPRVVREAQSRGMTRSMAAVDIAVQEPGEKVFVFGNAPTALFRLLEHRETAIGGVV
GVPVGFVGAAESKAALSESGLPAIAALGRKGGSNVAAAIVNALLYHLREAQ

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 22818; Mature: 22818

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYIQQPQAIEAKSFDIISEIIAETRPDYRFASPLHEAIIKRVIHTTADFDWLDILWFSP
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
DALIALSEALSRPCTLYTDTTMALSGINKTLLARFGGECRCYISDPRVVREAQSRGMTRS
HHHHHHHHHHCCCEEEEECHHHHHHHCHHHHHHHCCCCEEEEECCCHHHHHHHHCCCHHH
MAAVDIAVQEPGEKVFVFGNAPTALFRLLEHRETAIGGVVGVPVGFVGAAESKAALSESG
HHHEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHCCC
LPAIAALGRKGGSNVAAAIVNALLYHLREAQ
CHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQYIQQPQAIEAKSFDIISEIIAETRPDYRFASPLHEAIIKRVIHTTADFDWLDILWFSP
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
DALIALSEALSRPCTLYTDTTMALSGINKTLLARFGGECRCYISDPRVVREAQSRGMTRS
HHHHHHHHHHCCCEEEEECHHHHHHHCHHHHHHHCCCCEEEEECCCHHHHHHHHCCCHHH
MAAVDIAVQEPGEKVFVFGNAPTALFRLLEHRETAIGGVVGVPVGFVGAAESKAALSESG
HHHEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHCCC
LPAIAALGRKGGSNVAAAIVNALLYHLREAQ
CHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 1451790 [H]