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The map label for this gene is sdaB [H]

Identifier: 238896259

GI number: 238896259

Start: 4238118

End: 4239485

Strand: Direct

Name: sdaB [H]

Synonym: KP1_4416

Alternate gene names: 238896259

Gene position: 4238118-4239485 (Clockwise)

Preceding gene: 238896258

Following gene: 238896260

Centisome position: 80.75

GC content: 61.99

Gene sequence:

>1368_bases
ATGATCAGCGTATTCGATATCTTTAAAATCGGCATTGGCCCTTCCAGCTCCCATACCGTTGGACCGATGAAAGCGGGCAA
ACAATTCACTGACGACCTGATCGCGCGCGGCCTGCTGGCCGAGGTGAGAAAAGTCGTCGTCGACGTCTACGGCTCCCTCT
CCCTGACCGGTAAAGGCCACCATACCGATATCGCGATTATCATGGGACTCGCCGGCAACCTGCCGGACACGGTCGACATC
GACGCCATTCCGGGCTTTATTCAGGACGTTAATACCCATGGCCGCCTGATGCTGGCCAACGGTCAGCACGAAGTGGACTT
CCCGGTGGATCAGTGCATGAATTTCCATGCCGACAACCTGTCGCTGCATGAGAACGGCATGCGCATCACCGCCCTGGCCG
GCGACAAGGTGCTCTACAGCCAGACGTATTACTCTATCGGCGGCGGCTTTATCGTTGATGAGGAGCACTTCGGCCAGACT
ACCGAGGCGCCGGTTGCCGTTCCTTACCCTTACAAAAACGCCGCCGACCTGCAGCGTCACTGCCGTGAAACCGGGCTGTC
GCTCTCCGGCCTGATGATGCAGAACGAACTGGCGCTGCACAGCAAAGAAGCCCTTGAGCAACACTTCGCCGCGGTGTGGG
AAGTGATGAGCGCCGGTATCGAGCGCGGCATCACCACCGAAGGCGTCCTGCCGGGCAAACTGCGCGTCCCGCGCCGCGCC
GCCGCGCTGCGCCGCATGCTGGTGAGCCAGGACACCACCAACAGCGATCCGATGGCGGTGGTCGACTGGATCAATATGTT
CGCCCTGGCGGTGAACGAAGAGAACGCCGCCGGCGGCCGGGTGGTGACCGCGCCAACCAACGGCGCCTGCGGTATCGTGC
CGGCGGTGCTGGCCTACTACGACAAGTTTATCCGCAAGGTGAACAGCAACTCCCTGGCCCGCTATATGCTGGTCGCCAGC
GCGATTGGTTCGCTGTATAAGATGAACGCCTCCATCTCCGGCGCCGAAGTCGGCTGCCAGGGTGAAGTGGGGGTCGCCTG
CTCGATGGCGGCGGCCGGTCTGGCGGAACTGCTGGGCGGCAGCCCGGGTCAGGTGTGCATCGCGGCAGAGATCGCTATGG
AGCATAACCTCGGCCTGACCTGCGACCCGGTCGCCGGCCAGGTGCAGGTGCCGTGCATCGAACGCAACGCTATCGCTGCC
GTGAAAGCGGTCAACGCCGCGCGAATGGCGCTGCGCCGGACCAGCGAGCCGCGCGTGTGTCTCGATAAAGTGATCGAGAC
CATGTACGAAACCGGCAAAGACATGAACGCCAAGTACCGGGAAACCTCCCGCGGTGGTCTGGCGATGAAGATTGTTGCCT
GCGATTAA

Upstream 100 bases:

>100_bases
CCATCTCCGCGATCTTCTACTCTCTGTTCAGCTAATTCATTCAACGCCTCCCCCCGCGCCGCTTTACGGCGGCGCGCTTT
CCGACAGCACGGGAATACAT

Downstream 100 bases:

>100_bases
CCTGCTGGCCCGCCACGCGTCGGCGTGTCGGGCCATCGTCCTGCATAACTCTTTTTGTTATATCAATAAAATTTTAGTTA
TTTAATGGTTATAAGCGCTG

Product: L-serine deaminase 2

Products: NA

Alternate protein names: SDH 2; L-serine deaminase 2; L-SD2 [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARGLLAEVRKVVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDI
DAIPGFIQDVNTHGRLMLANGQHEVDFPVDQCMNFHADNLSLHENGMRITALAGDKVLYSQTYYSIGGGFIVDEEHFGQT
TEAPVAVPYPYKNAADLQRHCRETGLSLSGLMMQNELALHSKEALEQHFAAVWEVMSAGIERGITTEGVLPGKLRVPRRA
AALRRMLVSQDTTNSDPMAVVDWINMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYYDKFIRKVNSNSLARYMLVAS
AIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGGSPGQVCIAAEIAMEHNLGLTCDPVAGQVQVPCIERNAIAA
VKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMKIVACD

Sequences:

>Translated_455_residues
MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARGLLAEVRKVVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDI
DAIPGFIQDVNTHGRLMLANGQHEVDFPVDQCMNFHADNLSLHENGMRITALAGDKVLYSQTYYSIGGGFIVDEEHFGQT
TEAPVAVPYPYKNAADLQRHCRETGLSLSGLMMQNELALHSKEALEQHFAAVWEVMSAGIERGITTEGVLPGKLRVPRRA
AALRRMLVSQDTTNSDPMAVVDWINMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYYDKFIRKVNSNSLARYMLVAS
AIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGGSPGQVCIAAEIAMEHNLGLTCDPVAGQVQVPCIERNAIAA
VKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMKIVACD
>Mature_455_residues
MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARGLLAEVRKVVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDI
DAIPGFIQDVNTHGRLMLANGQHEVDFPVDQCMNFHADNLSLHENGMRITALAGDKVLYSQTYYSIGGGFIVDEEHFGQT
TEAPVAVPYPYKNAADLQRHCRETGLSLSGLMMQNELALHSKEALEQHFAAVWEVMSAGIERGITTEGVLPGKLRVPRRA
AALRRMLVSQDTTNSDPMAVVDWINMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYYDKFIRKVNSNSLARYMLVAS
AIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGGSPGQVCIAAEIAMEHNLGLTCDPVAGQVQVPCIERNAIAA
VKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMKIVACD

Specific function: Deaminates also threonine, particularly when it is present in high concentration [H]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=455, Percent_Identity=92.7472527472527, Blast_Score=883, Evalue=0.0,
Organism=Escherichia coli, GI1788116, Length=455, Percent_Identity=77.8021978021978, Blast_Score=736, Evalue=0.0,
Organism=Escherichia coli, GI48994925, Length=452, Percent_Identity=72.787610619469, Blast_Score=672, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 48556; Mature: 48556

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARGLLAEVRKVVVDVYGSLSLTGKGH
CCEEEEEEEECCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCC
HTDIAIIMGLAGNLPDTVDIDAIPGFIQDVNTHGRLMLANGQHEVDFPVDQCMNFHADNL
CCCEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCC
SLHENGMRITALAGDKVLYSQTYYSIGGGFIVDEEHFGQTTEAPVAVPYPYKNAADLQRH
EEECCCEEEEEEECCEEEEEEHHEECCCCEEEEHHHCCCCCCCCEEECCCCCCHHHHHHH
CRETGLSLSGLMMQNELALHSKEALEQHFAAVWEVMSAGIERGITTEGVLPGKLRVPRRA
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
AALRRMLVSQDTTNSDPMAVVDWINMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYY
HHHHHHHHHCCCCCCCCHHHHHHHHHHEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHH
DKFIRKVNSNSLARYMLVASAIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGG
HHHHHHHCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SPGQVCIAAEIAMEHNLGLTCDPVAGQVQVPCIERNAIAAVKAVNAARMALRRTSEPRVC
CCCCEEEEEEEHHHCCCCCEECCCCCCEECCEECCCHHHHHHHHHHHHHHHHCCCCCHHH
LDKVIETMYETGKDMNAKYRETSRGGLAMKIVACD
HHHHHHHHHHCCCCCCCHHHHCCCCCEEEEEEECC
>Mature Secondary Structure
MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARGLLAEVRKVVVDVYGSLSLTGKGH
CCEEEEEEEECCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCC
HTDIAIIMGLAGNLPDTVDIDAIPGFIQDVNTHGRLMLANGQHEVDFPVDQCMNFHADNL
CCCEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCC
SLHENGMRITALAGDKVLYSQTYYSIGGGFIVDEEHFGQTTEAPVAVPYPYKNAADLQRH
EEECCCEEEEEEECCEEEEEEHHEECCCCEEEEHHHCCCCCCCCEEECCCCCCHHHHHHH
CRETGLSLSGLMMQNELALHSKEALEQHFAAVWEVMSAGIERGITTEGVLPGKLRVPRRA
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
AALRRMLVSQDTTNSDPMAVVDWINMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYY
HHHHHHHHHCCCCCCCCHHHHHHHHHHEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHH
DKFIRKVNSNSLARYMLVASAIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGG
HHHHHHHCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SPGQVCIAAEIAMEHNLGLTCDPVAGQVQVPCIERNAIAAVKAVNAARMALRRTSEPRVC
CCCCEEEEEEEHHHCCCCCEECCCCCCEECCEECCCHHHHHHHHHHHHHHHHCCCCCHHH
LDKVIETMYETGKDMNAKYRETSRGGLAMKIVACD
HHHHHHHHHHCCCCCCCHHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8385012; 9278503 [H]