Click here to switch to the map view.

The map label for this gene is hycH [H]

Identifier: 238896175

GI number: 238896175

Start: 4147068

End: 4147478

Strand: Reverse

Name: hycH [H]

Synonym: KP1_4321

Alternate gene names: 238896175

Gene position: 4147478-4147068 (Counterclockwise)

Preceding gene: 238896176

Following gene: 238896174

Centisome position: 79.02

GC content: 59.85

Gene sequence:

>411_bases
ATGAGCGAGACGGTGGTGTTCAGTCAGCTGAGCCGTAAATTTATTGATGAGAACGACGCCACGCCGGATCAGGCGCAGCA
GGTGGTCTATTACAGCCTGGCGATTGGCCACCACCTCGGCGTCATCGACTGTCTGGAGGCGGCGCTGAGCTGCCCGTGGG
ACGCGTATCTGGCATGGATCGCCACCCTTGAGGCCGGAAGCGCCGCGCGGCGCAAAATGGAGGGCGTGCCGAAGTATGGC
GAAATCGTCATCGACAGCAGTCATGTGGCGATGCTGGCCAACGCCTTTGATAAAGCGCAGTCCGCGCAGACCCCGCAGCA
GCAGGCGTGGAGCAAAACCCTGCTCAGCATGCTGCATGATATTCACCAGGAGAGCGCCATCTACCTGATGGTGAGGAGAT
TACGTGACTGA

Upstream 100 bases:

>100_bases
GCGACAGCCAGGTGCTGCGCTGGCTGGAGGCGGAGAAAGATCCGCGTCTGACCGAGATCGTCACCCATCTCAACCAGGTG
GTCGAGGGGGCGCGTATCCG

Downstream 100 bases:

>100_bases
CGTTTTACTCTGTGTCGGCAACAGCATGATGGGCGACGACGGCGCCGGCCCGCTGCTGGCGGAGATGTGCGCGGCTAACC
CGGCCGGCCAGTGGGTGGTC

Product: formate hydrogenlyase maturation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MSETVVFSQLSRKFIDENDATPDQAQQVVYYSLAIGHHLGVIDCLEAALSCPWDAYLAWIATLEAGSAARRKMEGVPKYG
EIVIDSSHVAMLANAFDKAQSAQTPQQQAWSKTLLSMLHDIHQESAIYLMVRRLRD

Sequences:

>Translated_136_residues
MSETVVFSQLSRKFIDENDATPDQAQQVVYYSLAIGHHLGVIDCLEAALSCPWDAYLAWIATLEAGSAARRKMEGVPKYG
EIVIDSSHVAMLANAFDKAQSAQTPQQQAWSKTLLSMLHDIHQESAIYLMVRRLRD
>Mature_135_residues
SETVVFSQLSRKFIDENDATPDQAQQVVYYSLAIGHHLGVIDCLEAALSCPWDAYLAWIATLEAGSAARRKMEGVPKYGE
IVIDSSHVAMLANAFDKAQSAQTPQQQAWSKTLLSMLHDIHQESAIYLMVRRLRD

Specific function: Seems to be required for the conversion of a precursor form of the large subunit of hydrogenlyase (hycE) into a mature form [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hyfJ [H]

Homologues:

Organism=Escherichia coli, GI1789073, Length=136, Percent_Identity=88.2352941176471, Blast_Score=253, Evalue=4e-69,
Organism=Escherichia coli, GI87082116, Length=130, Percent_Identity=49.2307692307692, Blast_Score=125, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010005
- ProDom:   PD021295 [H]

Pfam domain/function: PF07450 HycH [H]

EC number: NA

Molecular weight: Translated: 15181; Mature: 15050

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETVVFSQLSRKFIDENDATPDQAQQVVYYSLAIGHHLGVIDCLEAALSCPWDAYLAWI
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHH
ATLEAGSAARRKMEGVPKYGEIVIDSSHVAMLANAFDKAQSAQTPQQQAWSKTLLSMLHD
HHHHCCHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IHQESAIYLMVRRLRD
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SETVVFSQLSRKFIDENDATPDQAQQVVYYSLAIGHHLGVIDCLEAALSCPWDAYLAWI
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHH
ATLEAGSAARRKMEGVPKYGEIVIDSSHVAMLANAFDKAQSAQTPQQQAWSKTLLSMLHD
HHHHCCHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IHQESAIYLMVRRLRD
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]