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The map label for this gene is yofA [H]

Identifier: 238895957

GI number: 238895957

Start: 3907867

End: 3908754

Strand: Reverse

Name: yofA [H]

Synonym: KP1_4082

Alternate gene names: 238895957

Gene position: 3908754-3907867 (Counterclockwise)

Preceding gene: 238895961

Following gene: 238895955

Centisome position: 74.47

GC content: 62.95

Gene sequence:

>888_bases
ATGACAACACTGAACCTGGGAAATCTGGCGACCTTCCGGCTGGTCGTACAGCGCGGCAGCTTTTCTGCCGCCGCCGACGC
GCTGGGGATCTCCCAACCTGCCGTCAGCCTGCAGGTACGTCAGCTGGAGCAGTTTTTACAGACCAGGCTGCTGGAGCGAA
CCGGACGTGGGATCAAGGCGACGGCGGCGGGAATGGCATTGCTGGCCCACAGCGAGCAGATCGATCGGGCGGTGAATAGC
GCGGTGCAGTCGGTCAGCGCATTCAGTCAGGAGGTTAATGGATCGTTGACGCTGGGGACCGGCGCGACGGCCTGCATTCA
TCTTCTTCCACCGCTGCTGCAGCATCTTCGTCAGCAGCACCCGCTGCTGACGGTGGGGGTGACCACCGGCAACACGCTGG
ATATCGTCCGCGCGGTGGAAGAAAACCGGCTCGATCTCGGGCTGGTCACGCTGCCCGTGCAGGGGCGCAGTCTGGCGGTG
ACTGCGATGTTAGATGAGGAGTTCGTGACCATCTATGCCAGCCGCGAGACGGAGATGCCGGCGGTTTATACTCCCGCCGA
GCTGCAGGCGCAGCCGCTCATTGCCTTCGAGGCGGGTAGCGGCACGCGGGATCTGATTGACCGCTGGTTCCGCTCGGCGG
GACTGGCGGTGACGCCGGTAATGCAGTTGGGGAGCATCGAGGCGATTAAGCGCATGGTGCGGGCAGGGCTGGGCTACAGC
ATCGTGCCCCGCATGGCGGTGGAGCGGGTGGAGGATCGCGACGGATTACGCGTACACTCGCTGGCGCCGCGGCTATATCG
ACAGCTGGCGGTAGTCATGCGTCAGGACAAAATTGTGACAAAAGGTATCGCTGAAATGCTGCGCCTGCTGCATACCGTGC
GCTTATAA

Upstream 100 bases:

>100_bases
CATGGTTTTTCATTCCGTTAAGACAGTTGTCCTGAGCATACCCGGCAGGCTATTGTTCTGGCAGAGCGGCTACCTTATGC
GCGGTATAAGAGAAACTTTT

Downstream 100 bases:

>100_bases
ATCGCCGACGGCAAAATTACCGCATCAAAGACAGTACTTCAGCAGCGAGCGGCTCTGCCTGCGGAGTGTGGCGCTTGCAG
TATTAGAATCAAAGGATTAC

Product: putative LysR-family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTTLNLGNLATFRLVVQRGSFSAAADALGISQPAVSLQVRQLEQFLQTRLLERTGRGIKATAAGMALLAHSEQIDRAVNS
AVQSVSAFSQEVNGSLTLGTGATACIHLLPPLLQHLRQQHPLLTVGVTTGNTLDIVRAVEENRLDLGLVTLPVQGRSLAV
TAMLDEEFVTIYASRETEMPAVYTPAELQAQPLIAFEAGSGTRDLIDRWFRSAGLAVTPVMQLGSIEAIKRMVRAGLGYS
IVPRMAVERVEDRDGLRVHSLAPRLYRQLAVVMRQDKIVTKGIAEMLRLLHTVRL

Sequences:

>Translated_295_residues
MTTLNLGNLATFRLVVQRGSFSAAADALGISQPAVSLQVRQLEQFLQTRLLERTGRGIKATAAGMALLAHSEQIDRAVNS
AVQSVSAFSQEVNGSLTLGTGATACIHLLPPLLQHLRQQHPLLTVGVTTGNTLDIVRAVEENRLDLGLVTLPVQGRSLAV
TAMLDEEFVTIYASRETEMPAVYTPAELQAQPLIAFEAGSGTRDLIDRWFRSAGLAVTPVMQLGSIEAIKRMVRAGLGYS
IVPRMAVERVEDRDGLRVHSLAPRLYRQLAVVMRQDKIVTKGIAEMLRLLHTVRL
>Mature_294_residues
TTLNLGNLATFRLVVQRGSFSAAADALGISQPAVSLQVRQLEQFLQTRLLERTGRGIKATAAGMALLAHSEQIDRAVNSA
VQSVSAFSQEVNGSLTLGTGATACIHLLPPLLQHLRQQHPLLTVGVTTGNTLDIVRAVEENRLDLGLVTLPVQGRSLAVT
AMLDEEFVTIYASRETEMPAVYTPAELQAQPLIAFEAGSGTRDLIDRWFRSAGLAVTPVMQLGSIEAIKRMVRAGLGYSI
VPRMAVERVEDRDGLRVHSLAPRLYRQLAVVMRQDKIVTKGIAEMLRLLHTVRL

Specific function: Regulates expression of the cell division protein ftsW, and is essential for cell viability during stationary phase [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=290, Percent_Identity=28.9655172413793, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788748, Length=276, Percent_Identity=28.6231884057971, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI157672245, Length=274, Percent_Identity=27.3722627737226, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790399, Length=273, Percent_Identity=27.1062271062271, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI145693105, Length=288, Percent_Identity=23.9583333333333, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082132, Length=246, Percent_Identity=28.0487804878049, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787879, Length=248, Percent_Identity=30.6451612903226, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787530, Length=253, Percent_Identity=28.4584980237154, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1789506, Length=238, Percent_Identity=23.109243697479, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790208, Length=256, Percent_Identity=25.78125, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789204, Length=247, Percent_Identity=25.9109311740891, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787806, Length=263, Percent_Identity=22.8136882129278, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790262, Length=276, Percent_Identity=26.8115942028986, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=27.2357723577236, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787601, Length=168, Percent_Identity=25, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI87081904, Length=145, Percent_Identity=31.0344827586207, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788887, Length=247, Percent_Identity=26.7206477732794, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787128, Length=135, Percent_Identity=31.8518518518519, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786401, Length=132, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789639, Length=125, Percent_Identity=32, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32092; Mature: 31961

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLNLGNLATFRLVVQRGSFSAAADALGISQPAVSLQVRQLEQFLQTRLLERTGRGIKA
CCEECCCCHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
TAAGMALLAHSEQIDRAVNSAVQSVSAFSQEVNGSLTLGTGATACIHLLPPLLQHLRQQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHC
PLLTVGVTTGNTLDIVRAVEENRLDLGLVTLPVQGRSLAVTAMLDEEFVTIYASRETEMP
CEEEEEECCCCHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEEECCCEEEEEECCCCCCC
AVYTPAELQAQPLIAFEAGSGTRDLIDRWFRSAGLAVTPVMQLGSIEAIKRMVRAGLGYS
EEECCHHCCCCCEEEEECCCCCHHHHHHHHHHCCCEEHHHHHHCCHHHHHHHHHHCCCHH
IVPRMAVERVEDRDGLRVHSLAPRLYRQLAVVMRQDKIVTKGIAEMLRLLHTVRL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTLNLGNLATFRLVVQRGSFSAAADALGISQPAVSLQVRQLEQFLQTRLLERTGRGIKA
CEECCCCHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
TAAGMALLAHSEQIDRAVNSAVQSVSAFSQEVNGSLTLGTGATACIHLLPPLLQHLRQQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHC
PLLTVGVTTGNTLDIVRAVEENRLDLGLVTLPVQGRSLAVTAMLDEEFVTIYASRETEMP
CEEEEEECCCCHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEEECCCEEEEEECCCCCCC
AVYTPAELQAQPLIAFEAGSGTRDLIDRWFRSAGLAVTPVMQLGSIEAIKRMVRAGLGYS
EEECCHHCCCCCEEEEECCCCCHHHHHHHHHHCCCEEHHHHHHCCHHHHHHHHHHCCCHH
IVPRMAVERVEDRDGLRVHSLAPRLYRQLAVVMRQDKIVTKGIAEMLRLLHTVRL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]