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The map label for this gene is aegA [H]

Identifier: 238895928

GI number: 238895928

Start: 3874023

End: 3876005

Strand: Reverse

Name: aegA [H]

Synonym: KP1_4053

Alternate gene names: 238895928

Gene position: 3876005-3874023 (Counterclockwise)

Preceding gene: 238895933

Following gene: 238895927

Centisome position: 73.85

GC content: 64.9

Gene sequence:

>1983_bases
ATGAACCACTTTATTTTGAGCGATAGCCGAAAGTGCATCGGCTGCCAGGCCTGCGAAGTGGCCTGCGTGATGGCGCATAA
CGAGGAGCAACACGTGCTGACCCCGCAGCGCTTTTTGCCACGTATCACCGTGATCAAAGCGGAGGGCCAGCGTAACGCCA
TCACCTGCCGCCACTGCGAGGACGCCCCCTGCGTCCGCAGTTGTCCCAACGACGCCATCGCCCAGTCCGGCGACAGCGTT
CAGGTCCGTCAGGAGAAATGCATTGGCTGTAAATCCTGCATGGTGGCCTGCCCGTTCGGGGTGATGCAGGTGGTGGTGAC
GCCGCAGGCCGCAGGCCTGGTGAAAGCCAGCGCGCACAAGTGCGATCTATGCCAGGGCCGCGAGGCGGGGCCGGCCTGTG
TGGAAAACTGTCCCGCGCAGGCGCTGACCCTCGCCGACGATGAGACGTTGATCACCCTGGCGAAGCAGCGGCGACTGCGC
TCGGCATGCCAGGAGGTGCAGCCGTGGCAGCGCGCTACGCCGCTCTGCAGCCAGCCCAATGCTGGCGCGAAGGTCAGGCA
AATGGCGATGACGCCCCCGCGCGGGGAGCCGGATAAGCTGGCGGCGGAGGTGCGTAAGAGCCACTTTGAGGAGATCTATC
AGCCGTTCACCCCGCAGCAGGCGCAGCAGCAGGCCGCCCGCTGTCTCACGTGTGGGGAGCACAGTATTTGCGAATGGACC
TGCCCGCTGCATAACCATATCCCGCAGTGGATTGAGCTGGTTAAAGCGGGGAATATCGCCGCCGCGGTCGCGCTTTCCCA
TCAGACCAACTGCCTGCCGGAGATCACCGGCCGCGTCTGTCCCCAGGGCCGGCTGTGTGAAGGCGCCTGCACCCTGCGCG
ATGAAAGCGGGGCAGTCACCATCGGCAATATTGAGCGCTATATTTCCGACCAGGCGCTGGCCAGCGGCTGGCGTCCGGAC
CTTTCGCAGGTTAAGCCGAGCGGCAAGCGGGTGGCGATTATCGGCGCCGGGCCGGCCGGGCTGGCCTGCGCCGATATGCT
GGTGCGCCACGGCGTCCAGCCGGTGGTCTTCGACCGTCATCCGGAGATTGGCGGTCTGCTGACCTTCGGCATTCCGGCGT
TCAAGCTGGATAAATCGCTATTGGCCCGGCGGCGGGCGATCTTCAGCGAGATGGGTATCCGCTTTGAGCTCAATTGCGAG
GTGGGGAAAGATATCTCCATGGCGACACTGCTGGCCGAGTATGACGCGGTGTTCGTCGGCGCCGGAACCTATCGCTCCAT
GAAGGCGGGGCTGCCGAACGAAGAGGCCCCCGGGGTCTACGATGCGCTGCCGTTCCTCATCGCCAACACCAAACAGGTGA
TGGGGCTGGCGGCATCGGCGCAAGAGCCTTATGTCAACACCGCCGGGCTGAACGTGGTGGTGCTGGGCGGCGGCGATACG
GCGATGGACTGCGTGCGCACCGCGCTGCGCCACGGCGCCCGCCAGGTGACCTGCGCCTATCGGCGAGATGAAGCCAACAT
GCCGGGCTCGAAAAAAGAGGTCAAAAACGCCCGCGAAGAGGGGGCGCTCTTTGAGTTTAACGTCCAGCCGGTGACGCTTG
AGCTGGACGAGAACGGGCGGGTTAACGGGGTTCGCTTTTTGCGCACCGAGCTGGGCGCTCCGGACGCCGGGGGAAGACGC
CGTCCGACGCCGATCCCCGGCAGCGAGTTTGTTATGCCGGCAGATGCGGTGATCATGGCCTTTGGCTTCCACCCGCACCG
CATGCCCTGGCTGGAGGCGGCGGGGGTGGCGCTGGACAGCCAGGGGCGTATTAAAGCCGGAGTGGAGAGCCGTTACCGTT
ATCAGACCAGTCAGGAGAAGATCTTTGCCGGCGGCGATGCCGTGCGCGGCGCAGACCTTGTAGTGACGGCGATGGCGGAA
GGCCGTCACGCGGCGCAGGGGATCCTGGACTATCTGGCGCGGAAAACGACGCCGCTTCACTGA

Upstream 100 bases:

>100_bases
TTTATCCTGGGCAATTGGACATTGTTCCGGCGTCATCTTGTCGGGTAATAAATAGGCATGCGCATTGAGGGGTTATTCAC
CAAGAAGACAAAAGGAAGCC

Downstream 100 bases:

>100_bases
CGACAAACCCGGCTCCGCAGCGTAGTATGAGGGCGTCCTTTTACGCTGTGGGGTCGGTATGTCACTCAATATTCACGTCA
TTAAAGATAAAATCCTCTCT

Product: putative oxidoreductase Fe-S binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MNHFILSDSRKCIGCQACEVACVMAHNEEQHVLTPQRFLPRITVIKAEGQRNAITCRHCEDAPCVRSCPNDAIAQSGDSV
QVRQEKCIGCKSCMVACPFGVMQVVVTPQAAGLVKASAHKCDLCQGREAGPACVENCPAQALTLADDETLITLAKQRRLR
SACQEVQPWQRATPLCSQPNAGAKVRQMAMTPPRGEPDKLAAEVRKSHFEEIYQPFTPQQAQQQAARCLTCGEHSICEWT
CPLHNHIPQWIELVKAGNIAAAVALSHQTNCLPEITGRVCPQGRLCEGACTLRDESGAVTIGNIERYISDQALASGWRPD
LSQVKPSGKRVAIIGAGPAGLACADMLVRHGVQPVVFDRHPEIGGLLTFGIPAFKLDKSLLARRRAIFSEMGIRFELNCE
VGKDISMATLLAEYDAVFVGAGTYRSMKAGLPNEEAPGVYDALPFLIANTKQVMGLAASAQEPYVNTAGLNVVVLGGGDT
AMDCVRTALRHGARQVTCAYRRDEANMPGSKKEVKNAREEGALFEFNVQPVTLELDENGRVNGVRFLRTELGAPDAGGRR
RPTPIPGSEFVMPADAVIMAFGFHPHRMPWLEAAGVALDSQGRIKAGVESRYRYQTSQEKIFAGGDAVRGADLVVTAMAE
GRHAAQGILDYLARKTTPLH

Sequences:

>Translated_660_residues
MNHFILSDSRKCIGCQACEVACVMAHNEEQHVLTPQRFLPRITVIKAEGQRNAITCRHCEDAPCVRSCPNDAIAQSGDSV
QVRQEKCIGCKSCMVACPFGVMQVVVTPQAAGLVKASAHKCDLCQGREAGPACVENCPAQALTLADDETLITLAKQRRLR
SACQEVQPWQRATPLCSQPNAGAKVRQMAMTPPRGEPDKLAAEVRKSHFEEIYQPFTPQQAQQQAARCLTCGEHSICEWT
CPLHNHIPQWIELVKAGNIAAAVALSHQTNCLPEITGRVCPQGRLCEGACTLRDESGAVTIGNIERYISDQALASGWRPD
LSQVKPSGKRVAIIGAGPAGLACADMLVRHGVQPVVFDRHPEIGGLLTFGIPAFKLDKSLLARRRAIFSEMGIRFELNCE
VGKDISMATLLAEYDAVFVGAGTYRSMKAGLPNEEAPGVYDALPFLIANTKQVMGLAASAQEPYVNTAGLNVVVLGGGDT
AMDCVRTALRHGARQVTCAYRRDEANMPGSKKEVKNAREEGALFEFNVQPVTLELDENGRVNGVRFLRTELGAPDAGGRR
RPTPIPGSEFVMPADAVIMAFGFHPHRMPWLEAAGVALDSQGRIKAGVESRYRYQTSQEKIFAGGDAVRGADLVVTAMAE
GRHAAQGILDYLARKTTPLH
>Mature_660_residues
MNHFILSDSRKCIGCQACEVACVMAHNEEQHVLTPQRFLPRITVIKAEGQRNAITCRHCEDAPCVRSCPNDAIAQSGDSV
QVRQEKCIGCKSCMVACPFGVMQVVVTPQAAGLVKASAHKCDLCQGREAGPACVENCPAQALTLADDETLITLAKQRRLR
SACQEVQPWQRATPLCSQPNAGAKVRQMAMTPPRGEPDKLAAEVRKSHFEEIYQPFTPQQAQQQAARCLTCGEHSICEWT
CPLHNHIPQWIELVKAGNIAAAVALSHQTNCLPEITGRVCPQGRLCEGACTLRDESGAVTIGNIERYISDQALASGWRPD
LSQVKPSGKRVAIIGAGPAGLACADMLVRHGVQPVVFDRHPEIGGLLTFGIPAFKLDKSLLARRRAIFSEMGIRFELNCE
VGKDISMATLLAEYDAVFVGAGTYRSMKAGLPNEEAPGVYDALPFLIANTKQVMGLAASAQEPYVNTAGLNVVVLGGGDT
AMDCVRTALRHGARQVTCAYRRDEANMPGSKKEVKNAREEGALFEFNVQPVTLELDENGRVNGVRFLRTELGAPDAGGRR
RPTPIPGSEFVMPADAVIMAFGFHPHRMPWLEAAGVALDSQGRIKAGVESRYRYQTSQEKIFAGGDAVRGADLVVTAMAE
GRHAAQGILDYLARKTTPLH

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=478, Percent_Identity=28.0334728033473, Blast_Score=154, Evalue=3e-37,
Organism=Escherichia coli, GI1788811, Length=660, Percent_Identity=76.2121212121212, Blast_Score=1048, Evalue=0.0,
Organism=Escherichia coli, GI87082180, Length=662, Percent_Identity=54.6827794561934, Blast_Score=727, Evalue=0.0,
Organism=Escherichia coli, GI1789606, Length=459, Percent_Identity=65.359477124183, Blast_Score=635, Evalue=0.0,
Organism=Escherichia coli, GI1788468, Length=448, Percent_Identity=31.25, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1789067, Length=172, Percent_Identity=52.9069767441861, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI2367245, Length=162, Percent_Identity=50.6172839506173, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1789243, Length=421, Percent_Identity=32.541567695962, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI87082179, Length=161, Percent_Identity=43.4782608695652, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1789079, Length=185, Percent_Identity=36.2162162162162, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI87082114, Length=195, Percent_Identity=32.8205128205128, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1787122, Length=159, Percent_Identity=33.9622641509434, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI2367345, Length=161, Percent_Identity=34.1614906832298, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790326, Length=174, Percent_Identity=31.6091954022989, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787872, Length=164, Percent_Identity=32.3170731707317, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787749, Length=174, Percent_Identity=31.0344827586207, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789370, Length=183, Percent_Identity=30.0546448087432, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI226510944, Length=153, Percent_Identity=32.6797385620915, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17570289, Length=488, Percent_Identity=33.6065573770492, Blast_Score=221, Evalue=8e-58,
Organism=Caenorhabditis elegans, GI71984108, Length=466, Percent_Identity=29.8283261802575, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17543860, Length=172, Percent_Identity=32.5581395348837, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320030, Length=478, Percent_Identity=32.8451882845188, Blast_Score=216, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24665547, Length=497, Percent_Identity=37.625754527163, Blast_Score=274, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24665543, Length=497, Percent_Identity=37.625754527163, Blast_Score=274, Evalue=1e-73,
Organism=Drosophila melanogaster, GI28574881, Length=497, Percent_Identity=37.625754527163, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24665539, Length=497, Percent_Identity=37.625754527163, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24640763, Length=463, Percent_Identity=29.1576673866091, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI18858217, Length=463, Percent_Identity=29.1576673866091, Blast_Score=158, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006006 [H]

Pfam domain/function: PF00037 Fer4; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 71393; Mature: 71393

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHFILSDSRKCIGCQACEVACVMAHNEEQHVLTPQRFLPRITVIKAEGQRNAITCRHCE
CCCEEECCCCCCCCCHHHHEEEEEECCCCCCEECHHHHCCEEEEEEECCCCCCEEEECCC
DAPCVRSCPNDAIAQSGDSVQVRQEKCIGCKSCMVACPFGVMQVVVTPQAAGLVKASAHK
CCCHHHCCCCHHHHCCCCCEEEHHHHHCCHHHHHHHCCHHHEEEEECCCHHCCEECCCCC
CDLCQGREAGPACVENCPAQALTLADDETLITLAKQRRLRSACQEVQPWQRATPLCSQPN
CCCCCCCCCCCHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCC
AGAKVRQMAMTPPRGEPDKLAAEVRKSHFEEIYQPFTPQQAQQQAARCLTCGEHSICEWT
CCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEE
CPLHNHIPQWIELVKAGNIAAAVALSHQTNCLPEITGRVCPQGRLCEGACTLRDESGAVT
CCHHHCCHHHHHHHHCCCEEEEEEECCCCCCCHHHHHCCCCCCCEECCEEEEECCCCCEE
IGNIERYISDQALASGWRPDLSQVKPSGKRVAIIGAGPAGLACADMLVRHGVQPVVFDRH
ECCHHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEECCC
PEIGGLLTFGIPAFKLDKSLLARRRAIFSEMGIRFELNCEVGKDISMATLLAEYDAVFVG
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCEEEEE
AGTYRSMKAGLPNEEAPGVYDALPFLIANTKQVMGLAASAQEPYVNTAGLNVVVLGGGDT
CCCHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCEEECCCEEEEECCCCH
AMDCVRTALRHGARQVTCAYRRDEANMPGSKKEVKNAREEGALFEFNVQPVTLELDENGR
HHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEECEEEEEEECCCCC
VNGVRFLRTELGAPDAGGRRRPTPIPGSEFVMPADAVIMAFGFHPHRMPWLEAAGVALDS
CCCEEEEHHHCCCCCCCCCCCCCCCCCCCEECCHHHEEEEECCCCCCCCHHHHCCEEECC
QGRIKAGVESRYRYQTSQEKIFAGGDAVRGADLVVTAMAEGRHAAQGILDYLARKTTPLH
CCCEECCHHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNHFILSDSRKCIGCQACEVACVMAHNEEQHVLTPQRFLPRITVIKAEGQRNAITCRHCE
CCCEEECCCCCCCCCHHHHEEEEEECCCCCCEECHHHHCCEEEEEEECCCCCCEEEECCC
DAPCVRSCPNDAIAQSGDSVQVRQEKCIGCKSCMVACPFGVMQVVVTPQAAGLVKASAHK
CCCHHHCCCCHHHHCCCCCEEEHHHHHCCHHHHHHHCCHHHEEEEECCCHHCCEECCCCC
CDLCQGREAGPACVENCPAQALTLADDETLITLAKQRRLRSACQEVQPWQRATPLCSQPN
CCCCCCCCCCCHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCC
AGAKVRQMAMTPPRGEPDKLAAEVRKSHFEEIYQPFTPQQAQQQAARCLTCGEHSICEWT
CCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEE
CPLHNHIPQWIELVKAGNIAAAVALSHQTNCLPEITGRVCPQGRLCEGACTLRDESGAVT
CCHHHCCHHHHHHHHCCCEEEEEEECCCCCCCHHHHHCCCCCCCEECCEEEEECCCCCEE
IGNIERYISDQALASGWRPDLSQVKPSGKRVAIIGAGPAGLACADMLVRHGVQPVVFDRH
ECCHHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEECCC
PEIGGLLTFGIPAFKLDKSLLARRRAIFSEMGIRFELNCEVGKDISMATLLAEYDAVFVG
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCEEEEE
AGTYRSMKAGLPNEEAPGVYDALPFLIANTKQVMGLAASAQEPYVNTAGLNVVVLGGGDT
CCCHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCEEECCCEEEEECCCCH
AMDCVRTALRHGARQVTCAYRRDEANMPGSKKEVKNAREEGALFEFNVQPVTLELDENGR
HHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEECEEEEEEECCCCC
VNGVRFLRTELGAPDAGGRRRPTPIPGSEFVMPADAVIMAFGFHPHRMPWLEAAGVALDS
CCCEEEEHHHCCCCCCCCCCCCCCCCCCCEECCHHHEEEEECCCCCCCCHHHHCCEEECC
QGRIKAGVESRYRYQTSQEKIFAGGDAVRGADLVVTAMAEGRHAAQGILDYLARKTTPLH
CCCEECCHHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8955321; 9205837; 9278503 [H]