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The map label for this gene is yffH

Identifier: 238895927

GI number: 238895927

Start: 3873368

End: 3873964

Strand: Reverse

Name: yffH

Synonym: KP1_4052

Alternate gene names: 238895927

Gene position: 3873964-3873368 (Counterclockwise)

Preceding gene: 238895928

Following gene: 238895926

Centisome position: 73.81

GC content: 57.45

Gene sequence:

>597_bases
ATGTCACTCAATATTCACGTCATTAAAGATAAAATCCTCTCTGAGAACTGGTTCGTACTACGCAATATGACCTATGAGCT
GACGCGGGCGGACGGCAGCGTTGTGCGCCACAAGCGCGAGGTCTACGATCGCGGCAATGGCGCCACCGTGCTGCTGTATA
ACCGCCATAAGCAGACGGTGGTCCTGGTGCGTCAGTTCCGTGTCGCCACCTGGGTCAATGGCAATCATGACGGCATGCTG
ATTGAAACCTGCGCCGGGCTGCTGGACAACGACGAGCCGGAAGCCTGCATTCGTAAAGAGGCGGTGGAAGAGACCGGCTA
CGAAGTGGGCGAGGTGAGAAAGCTGTTTGAGCTGTTTATGTCGCCAGGGGGCGTCACCGAGGTAGTGCATTTCTTTATCG
CCGAGTACAGCGACGCGCAGCGAACCACCAGCGGCGGCGGGGTGGATGATGAAGCCATCGAGGTGCTGGAGCTGCCTTTT
AGCCAGGCGCTGCAGATGGTCGCTGACGGGGAGATCCGCGACGGTAAGGCGGTCATTCTGCTGCAATATCTGCAAACCTC
CGGCCTGATGTCGGGGAACTCTGACAAATCCGATTGA

Upstream 100 bases:

>100_bases
ATCCTGGACTATCTGGCGCGGAAAACGACGCCGCTTCACTGACGACAAACCCGGCTCCGCAGCGTAGTATGAGGGCGTCC
TTTTACGCTGTGGGGTCGGT

Downstream 100 bases:

>100_bases
GTAACCCGCTGCCGTTGTCCAGGATAGGCGCCGTGGTCGGGTTTATCTGGGGTCGGGCGGTTCATGCTTTTTCGCGTCAT
CTTTTTCCTTTTTCTGGCGG

Product: putative pyrophosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MSLNIHVIKDKILSENWFVLRNMTYELTRADGSVVRHKREVYDRGNGATVLLYNRHKQTVVLVRQFRVATWVNGNHDGML
IETCAGLLDNDEPEACIRKEAVEETGYEVGEVRKLFELFMSPGGVTEVVHFFIAEYSDAQRTTSGGGVDDEAIEVLELPF
SQALQMVADGEIRDGKAVILLQYLQTSGLMSGNSDKSD

Sequences:

>Translated_198_residues
MSLNIHVIKDKILSENWFVLRNMTYELTRADGSVVRHKREVYDRGNGATVLLYNRHKQTVVLVRQFRVATWVNGNHDGML
IETCAGLLDNDEPEACIRKEAVEETGYEVGEVRKLFELFMSPGGVTEVVHFFIAEYSDAQRTTSGGGVDDEAIEVLELPF
SQALQMVADGEIRDGKAVILLQYLQTSGLMSGNSDKSD
>Mature_197_residues
SLNIHVIKDKILSENWFVLRNMTYELTRADGSVVRHKREVYDRGNGATVLLYNRHKQTVVLVRQFRVATWVNGNHDGMLI
ETCAGLLDNDEPEACIRKEAVEETGYEVGEVRKLFELFMSPGGVTEVVHFFIAEYSDAQRTTSGGGVDDEAIEVLELPFS
QALQMVADGEIRDGKAVILLQYLQTSGLMSGNSDKSD

Specific function: Catalyzes the hydrolysis of GDP-mannose

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1788810, Length=190, Percent_Identity=77.8947368421053, Blast_Score=319, Evalue=9e-89,
Organism=Escherichia coli, GI1789412, Length=151, Percent_Identity=33.112582781457, Blast_Score=78, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24650557, Length=157, Percent_Identity=33.7579617834395, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUDK_KLEP7 (A6TC90)

Other databases:

- EMBL:   CP000647
- RefSeq:   YP_001336441.1
- ProteinModelPortal:   A6TC90
- SMR:   A6TC90
- STRING:   A6TC90
- GeneID:   5340331
- GenomeReviews:   CP000647_GR
- KEGG:   kpn:KPN_02801
- eggNOG:   COG0494
- HOGENOM:   HBG692398
- OMA:   WHVLRRT
- ProtClustDB:   PRK15009
- InterPro:   IPR004385
- InterPro:   IPR000086
- InterPro:   IPR015797
- Gene3D:   G3DSA:3.90.79.10
- TIGRFAMs:   TIGR00052

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: NA

Molecular weight: Translated: 22157; Mature: 22026

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNIHVIKDKILSENWFVLRNMTYELTRADGSVVRHKREVYDRGNGATVLLYNRHKQTV
CCCEEEEEHHHHHCCCEEEEECCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCEE
VLVRQFRVATWVNGNHDGMLIETCAGLLDNDEPEACIRKEAVEETGYEVGEVRKLFELFM
HHHHHHHHHEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHC
SPGGVTEVVHFFIAEYSDAQRTTSGGGVDDEAIEVLELPFSQALQMVADGEIRDGKAVIL
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEH
LQYLQTSGLMSGNSDKSD
EEEHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SLNIHVIKDKILSENWFVLRNMTYELTRADGSVVRHKREVYDRGNGATVLLYNRHKQTV
CCEEEEEHHHHHCCCEEEEECCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCEE
VLVRQFRVATWVNGNHDGMLIETCAGLLDNDEPEACIRKEAVEETGYEVGEVRKLFELFM
HHHHHHHHHEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHC
SPGGVTEVVHFFIAEYSDAQRTTSGGGVDDEAIEVLELPFSQALQMVADGEIRDGKAVIL
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEH
LQYLQTSGLMSGNSDKSD
EEEHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA