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The map label for this gene is nuoH [H]

Identifier: 238895799

GI number: 238895799

Start: 3744949

End: 3745926

Strand: Reverse

Name: nuoH [H]

Synonym: KP1_3915

Alternate gene names: 238895799

Gene position: 3745926-3744949 (Counterclockwise)

Preceding gene: 238895800

Following gene: 238895798

Centisome position: 71.37

GC content: 57.16

Gene sequence:

>978_bases
ATGAGCTGGTTAACGCCGGATCTTATCGACATTCTGTTAAGCATCCTGAAGGCCGTGGTCATTCTGCTGGTGGTTGTCAC
CTGCGGCGCGTTCATGAGCTTCGGCGAGCGTCGTCTGCTCGGCTTGTTCCAGAACCGCTACGGACCTAACCGCGTCGGCT
GGGGCGGTTCGCTGCAGCTGGTCGCCGACATGATCAAGATGTTCTTTAAAGAGGACTGGATCCCGCGCTTCTCCGATCGC
GTGATCTTTACTCTGGCGCCGGTTATCGCCTTTACCTCGCTGCTGCTGGCCTTCGCTATCGTGCCGGTTAGCCCGACGTG
GGTGGTGGCCGACCTGAACATCGGCATCCTCTTCTTCCTGATGATGGCAGGCCTGGCGGTCTACGCGGTGCTGTTCGCCG
GTTGGTCGAGCAATAACAAATACTCGCTGCTGGGGGCGATGCGTGCTTCCGCGCAGACCCTGAGCTACGAAGTGTTTCTC
GGTCTCTCCCTGATGGGCGTGGTGGCGCAGGCGGGGTCATTCAATATGACCGATATCGTCAACAACCAGGCGCATCTGTG
GAACGTTATCCCGCAGTTCTTCGGCTTCGTGACTTTCGCCATCGCCGGCGTGGCGGTGTGTCACCGTCACCCGTTCGACC
AGCCGGAAGTGGAGCAGGAACTGGCCGATGGTTACCACATTGAATATTCCGGCATGAAATTCGGTCTGTTCTTCGTCGGG
GAATACATCGGTATCGTCACCGTTTCAGCGCTGATCGTCACGCTGTTCTTCGGCGGCTGGAATGGCCCGTGGTTACCTCC
TTTCATCTGGTTCGCGCTGAAAACCGCGTTCTTCATGATGATGTTCATTTTGATCCGCGCATCATTACCGCGTCCGCGCT
ATGACCAGGTAATGTCCTTTGGCTGGAAGGTATGCCTGCCGTTAACGCTGGTCAACTTGTTGGTAACGGCGGCTGTCATT
CTCTGGCAGGCGCAATAA

Upstream 100 bases:

>100_bases
AAGGCCTGACCGCGGGACAGGTTGGCTTACCGATGGGCATGCCGGGCATTGCGCCGGTGCTGACCGGATCGCGTATTGAT
TCACTGCAGGAGGCGAAAGC

Downstream 100 bases:

>100_bases
GGGGTGAATTGAACATGACCTTAAAAGAATTATTGGTGGGGTTTGGCACCCAGGTCCGTAGTATCTGGATGATTGGCCTG
CATGCCTTCGCCAAACGTGA

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSWLTPDLIDILLSILKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWIPRFSDR
VIFTLAPVIAFTSLLLAFAIVPVSPTWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFL
GLSLMGVVAQAGSFNMTDIVNNQAHLWNVIPQFFGFVTFAIAGVAVCHRHPFDQPEVEQELADGYHIEYSGMKFGLFFVG
EYIGIVTVSALIVTLFFGGWNGPWLPPFIWFALKTAFFMMMFILIRASLPRPRYDQVMSFGWKVCLPLTLVNLLVTAAVI
LWQAQ

Sequences:

>Translated_325_residues
MSWLTPDLIDILLSILKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWIPRFSDR
VIFTLAPVIAFTSLLLAFAIVPVSPTWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFL
GLSLMGVVAQAGSFNMTDIVNNQAHLWNVIPQFFGFVTFAIAGVAVCHRHPFDQPEVEQELADGYHIEYSGMKFGLFFVG
EYIGIVTVSALIVTLFFGGWNGPWLPPFIWFALKTAFFMMMFILIRASLPRPRYDQVMSFGWKVCLPLTLVNLLVTAAVI
LWQAQ
>Mature_324_residues
SWLTPDLIDILLSILKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWIPRFSDRV
IFTLAPVIAFTSLLLAFAIVPVSPTWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFLG
LSLMGVVAQAGSFNMTDIVNNQAHLWNVIPQFFGFVTFAIAGVAVCHRHPFDQPEVEQELADGYHIEYSGMKFGLFFVGE
YIGIVTVSALIVTLFFGGWNGPWLPPFIWFALKTAFFMMMFILIRASLPRPRYDQVMSFGWKVCLPLTLVNLLVTAAVIL
WQAQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=287, Percent_Identity=41.4634146341463, Blast_Score=197, Evalue=1e-50,
Organism=Escherichia coli, GI1788618, Length=325, Percent_Identity=94.4615384615385, Blast_Score=630, Evalue=0.0,
Organism=Escherichia coli, GI1789077, Length=258, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 36286; Mature: 36154

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00667 COMPLEX1_ND1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWLTPDLIDILLSILKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
VADMIKMFFKEDWIPRFSDRVIFTLAPVIAFTSLLLAFAIVPVSPTWVVADLNIGILFFL
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHH
MMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFLGLSLMGVVAQAGSFNMTDIV
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
NNQAHLWNVIPQFFGFVTFAIAGVAVCHRHPFDQPEVEQELADGYHIEYSGMKFGLFFVG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCCEEHHHHHH
EYIGIVTVSALIVTLFFGGWNGPWLPPFIWFALKTAFFMMMFILIRASLPRPRYDQVMSF
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHC
GWKVCLPLTLVNLLVTAAVILWQAQ
CHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SWLTPDLIDILLSILKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH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CHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA