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The map label for this gene is yfaV [H]

Identifier: 238895778

GI number: 238895778

Start: 3722651

End: 3723940

Strand: Reverse

Name: yfaV [H]

Synonym: KP1_3886

Alternate gene names: 238895778

Gene position: 3723940-3722651 (Counterclockwise)

Preceding gene: 238895779

Following gene: 238895777

Centisome position: 70.95

GC content: 62.33

Gene sequence:

>1290_bases
ATGAGCAACACTCTGCTGGAGAGCGTGGTGAAGAAAAACCGCGCCCGCTTAATCCCCTTTATGCTGGCGCTGTACGTGCT
GGCGTTTCTTGACCGTTCTAATATCGGTTTCGCCAAAGAGACCTACCAGCTGGATACCGGACTCAGCAATGAGGCCTACG
CGCTGGGGGCCGGTATCTTCTTTGTGGTCTATGCCTTCCTCTGGGTGCCGGCCAATCTGCTGATGCGCAAATTTGGCGCC
AGGCGATGGATCGGCTGCACCACGCTGCTGTGGGGCGTGCTGTCGGCGGCGATGGCGTGGGCGGATACGGAAGCGAAATT
CCTGCTGGTACGTACCCTGCTGGGCGCGGCGGAGGCGGGCTTCTTTCCCGGAATGATCTACCTCACTTCACAGTGGTTTC
CCCAGCAAAACCGCGCCAGCATTATGGGGCTGTTTTATATGGGCGCGCCGCTGGCCCTGACGCTGGGATCGCCTTTATCC
GGTGCGCTGCTGGAGATGCATGGATTTATGGGCCATCCCGGCTGGTTCTGGATGTTTGTCATTGAAGGCCTGCTCGCCGT
CGCCGCGGGAGCGTTCACCTTCTTCTGGCTGGACGATTCGCCGCAGCATGCCCGCTTCCTGAGCGCAGCGGAGAAACAGT
CGCTGATAAGCGAGCTGGCGCGCGAGGAGGAGAAAAAGATTGCCTCGCGCCTGTCCGATGCGCTGCGTAACGGGCGGGTC
TGGCAGCTGGCGCTGATTTATCTGACCATTCAGGTGGCGGTCTATGGTCTGATTTTCTTCCTGCCCACCCAGGTTGCTGC
GCTGCTGGGCACCAAAGTCGGCTTTGTTGCCTCGGTGGTGACGGCCATCCCGTGGGTGGCGGCGCTGTTTGGCACCTGGC
TTATCCCTCGCTACTCCGATCGCACCGGCGAGCGGCGCAATATTGCCGCCCTGACGCTGCTGGCGGCGGCGGTCGGGATT
GCGGTGTCCGGACTGGTGGCGCCGGTGCTGGCTATCATCGCGCTGTGCGTGGCGGCGGTCGGGGTGATCGCCGTGCAGCC
GGTCTTCTGGACGATGCCGACGCAGCTGCTGTCCGGCACGGCGCTGGCCGCAGGGATTGGCTTTGTTAACCTGTTTGGCG
CCATCGGTGGTTTTCTGGCGCCGATCGTGCGCGTGCAGGCCGAAACGTTGTTCGCCAGCAGCGCCGCCGGACTGTTAACC
CTGGCCGGCGTCGCCATTGTCGGGGTGGTCATTATCTTTTCATTGAGCCTTACCCGCGCGGTACCCCAGCGCGGCAGCGT
ACAGCATTGA

Upstream 100 bases:

>100_bases
CGGCTTTGGCGTCGAGCTCAATCGCGACTGCAACCTGAAGCGTCCTTATCAACACTGATTGCGTCAGGCCGCCCGGCGGC
CCGCGCCTGAGGATATTATG

Downstream 100 bases:

>100_bases
ATAAAGGAATCGCTATGAACGCACTGTTATCTAACCCCTTCAAACGGGGATTATTACGCGGTGAGACGCAAATCGGCCTG
TGGCTGAGCTCCACCTCATC

Product: putative transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSNTLLESVVKKNRARLIPFMLALYVLAFLDRSNIGFAKETYQLDTGLSNEAYALGAGIFFVVYAFLWVPANLLMRKFGA
RRWIGCTTLLWGVLSAAMAWADTEAKFLLVRTLLGAAEAGFFPGMIYLTSQWFPQQNRASIMGLFYMGAPLALTLGSPLS
GALLEMHGFMGHPGWFWMFVIEGLLAVAAGAFTFFWLDDSPQHARFLSAAEKQSLISELAREEEKKIASRLSDALRNGRV
WQLALIYLTIQVAVYGLIFFLPTQVAALLGTKVGFVASVVTAIPWVAALFGTWLIPRYSDRTGERRNIAALTLLAAAVGI
AVSGLVAPVLAIIALCVAAVGVIAVQPVFWTMPTQLLSGTALAAGIGFVNLFGAIGGFLAPIVRVQAETLFASSAAGLLT
LAGVAIVGVVIIFSLSLTRAVPQRGSVQH

Sequences:

>Translated_429_residues
MSNTLLESVVKKNRARLIPFMLALYVLAFLDRSNIGFAKETYQLDTGLSNEAYALGAGIFFVVYAFLWVPANLLMRKFGA
RRWIGCTTLLWGVLSAAMAWADTEAKFLLVRTLLGAAEAGFFPGMIYLTSQWFPQQNRASIMGLFYMGAPLALTLGSPLS
GALLEMHGFMGHPGWFWMFVIEGLLAVAAGAFTFFWLDDSPQHARFLSAAEKQSLISELAREEEKKIASRLSDALRNGRV
WQLALIYLTIQVAVYGLIFFLPTQVAALLGTKVGFVASVVTAIPWVAALFGTWLIPRYSDRTGERRNIAALTLLAAAVGI
AVSGLVAPVLAIIALCVAAVGVIAVQPVFWTMPTQLLSGTALAAGIGFVNLFGAIGGFLAPIVRVQAETLFASSAAGLLT
LAGVAIVGVVIIFSLSLTRAVPQRGSVQH
>Mature_428_residues
SNTLLESVVKKNRARLIPFMLALYVLAFLDRSNIGFAKETYQLDTGLSNEAYALGAGIFFVVYAFLWVPANLLMRKFGAR
RWIGCTTLLWGVLSAAMAWADTEAKFLLVRTLLGAAEAGFFPGMIYLTSQWFPQQNRASIMGLFYMGAPLALTLGSPLSG
ALLEMHGFMGHPGWFWMFVIEGLLAVAAGAFTFFWLDDSPQHARFLSAAEKQSLISELAREEEKKIASRLSDALRNGRVW
QLALIYLTIQVAVYGLIFFLPTQVAALLGTKVGFVASVVTAIPWVAALFGTWLIPRYSDRTGERRNIAALTLLAAAVGIA
VSGLVAPVLAIIALCVAAVGVIAVQPVFWTMPTQLLSGTALAAGIGFVNLFGAIGGFLAPIVRVQAETLFASSAAGLLTL
AGVAIVGVVIIFSLSLTRAVPQRGSVQH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=386, Percent_Identity=24.0932642487047, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87082071, Length=429, Percent_Identity=84.6153846153846, Blast_Score=736, Evalue=0.0,
Organism=Escherichia coli, GI1789152, Length=419, Percent_Identity=23.1503579952267, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI2367379, Length=264, Percent_Identity=23.8636363636364, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082320, Length=393, Percent_Identity=20.8651399491094, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI2367193, Length=239, Percent_Identity=24.6861924686192, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=215, Percent_Identity=29.3023255813954, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6323032, Length=258, Percent_Identity=27.5193798449612, Blast_Score=93, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6321698, Length=328, Percent_Identity=24.0853658536585, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322612, Length=270, Percent_Identity=22.962962962963, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20130167, Length=256, Percent_Identity=28.125, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46098; Mature: 45967

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTLLESVVKKNRARLIPFMLALYVLAFLDRSNIGFAKETYQLDTGLSNEAYALGAGIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHH
FVVYAFLWVPANLLMRKFGARRWIGCTTLLWGVLSAAMAWADTEAKFLLVRTLLGAAEAG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
FFPGMIYLTSQWFPQQNRASIMGLFYMGAPLALTLGSPLSGALLEMHGFMGHPGWFWMFV
CCCCHHHHHCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCHHHHHHH
IEGLLAVAAGAFTFFWLDDSPQHARFLSAAEKQSLISELAREEEKKIASRLSDALRNGRV
HHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
WQLALIYLTIQVAVYGLIFFLPTQVAALLGTKVGFVASVVTAIPWVAALFGTWLIPRYSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RTGERRNIAALTLLAAAVGIAVSGLVAPVLAIIALCVAAVGVIAVQPVFWTMPTQLLSGT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ALAAGIGFVNLFGAIGGFLAPIVRVQAETLFASSAAGLLTLAGVAIVGVVIIFSLSLTRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPQRGSVQH
CCCCCCCCC
>Mature Secondary Structure 
SNTLLESVVKKNRARLIPFMLALYVLAFLDRSNIGFAKETYQLDTGLSNEAYALGAGIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHH
FVVYAFLWVPANLLMRKFGARRWIGCTTLLWGVLSAAMAWADTEAKFLLVRTLLGAAEAG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
FFPGMIYLTSQWFPQQNRASIMGLFYMGAPLALTLGSPLSGALLEMHGFMGHPGWFWMFV
CCCCHHHHHCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCHHHHHHH
IEGLLAVAAGAFTFFWLDDSPQHARFLSAAEKQSLISELAREEEKKIASRLSDALRNGRV
HHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
WQLALIYLTIQVAVYGLIFFLPTQVAALLGTKVGFVASVVTAIPWVAALFGTWLIPRYSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RTGERRNIAALTLLAAAVGIAVSGLVAPVLAIIALCVAAVGVIAVQPVFWTMPTQLLSGT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ALAAGIGFVNLFGAIGGFLAPIVRVQAETLFASSAAGLLTLAGVAIVGVVIIFSLSLTRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPQRGSVQH
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]