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The map label for this gene is eco [H]

Identifier: 238895754

GI number: 238895754

Start: 3688891

End: 3689334

Strand: Direct

Name: eco [H]

Synonym: KP1_3859

Alternate gene names: 238895754

Gene position: 3688891-3689334 (Clockwise)

Preceding gene: 238895753

Following gene: 238895756

Centisome position: 70.28

GC content: 56.76

Gene sequence:

>444_bases
ATGTCCGCTGGCGCATTGGCCGCAGACCAGCCGCTGGAAAAAGTCGCGCCGTTCCCGAAAGCGGAAAAAGGCATGAAGCG
TCAGGTTATTCAGCTGCCGCAGCAGCAGGATGAGTCGGCGCTCAAGGTTGAGCTGATGATCGGCCAGACGCTGGAAGTCG
ACTGCAACCATCATCGTCTCGGCGGGGAACTGGAAAGTAAAACCCTGGAAGGCTGGGGCTATGATTACTATGTCTTTGAG
AAGCTGAGCGGCCCGGTATCCACTATGATGGCCTGCCCGGACGGCAAAAAAGAGAAGAAATTTGTCACTGCCGGCCTCGG
GGATGACGCCATGTTGCGCTACAACAGCAAACTGCCGATCGTGGTATACACGCCGAGCAATGTCGATGTGAAATATCGCA
TCTGGCGCGCCGACGAGACTATCGGCAACGCCGTCGTCCGCTAA

Upstream 100 bases:

>100_bases
TGAGTGATGATAGGCTATCTCTGTCAGGAACGAAAATAAAGGATGATCAACCGTGAAAAAAATCACTACGCTAGCCGTTT
CTCTGCTGACCGCCGCCTGC

Downstream 100 bases:

>100_bases
GGCGAACAGCGCAAACGGCAATAAAAAACGGCAGCCCGCAGGCTGCCGTTTTTGTCAGAGCGTTTATCAGAGCGCGATAT
CCGCCATCGGCTTGCCGCCG

Product: ecotin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MSAGALAADQPLEKVAPFPKAEKGMKRQVIQLPQQQDESALKVELMIGQTLEVDCNHHRLGGELESKTLEGWGYDYYVFE
KLSGPVSTMMACPDGKKEKKFVTAGLGDDAMLRYNSKLPIVVYTPSNVDVKYRIWRADETIGNAVVR

Sequences:

>Translated_147_residues
MSAGALAADQPLEKVAPFPKAEKGMKRQVIQLPQQQDESALKVELMIGQTLEVDCNHHRLGGELESKTLEGWGYDYYVFE
KLSGPVSTMMACPDGKKEKKFVTAGLGDDAMLRYNSKLPIVVYTPSNVDVKYRIWRADETIGNAVVR
>Mature_146_residues
SAGALAADQPLEKVAPFPKAEKGMKRQVIQLPQQQDESALKVELMIGQTLEVDCNHHRLGGELESKTLEGWGYDYYVFEK
LSGPVSTMMACPDGKKEKKFVTAGLGDDAMLRYNSKLPIVVYTPSNVDVKYRIWRADETIGNAVVR

Specific function: General inhibitor of pancreatic serine proteases:inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases [H]

COG id: COG4574

COG function: function code R; Serine protease inhibitor ecotin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease inhibitor I11 (ecotin) family [H]

Homologues:

Organism=Escherichia coli, GI1788538, Length=146, Percent_Identity=80.8219178082192, Blast_Score=249, Evalue=4e-68,

Paralogues:

None

Copy number: 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005658
- InterPro:   IPR023189
- InterPro:   IPR023084 [H]

Pfam domain/function: PF03974 Ecotin [H]

EC number: NA

Molecular weight: Translated: 16348; Mature: 16217

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGALAADQPLEKVAPFPKAEKGMKRQVIQLPQQQDESALKVELMIGQTLEVDCNHHRL
CCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCEEEECCCCCCC
GGELESKTLEGWGYDYYVFEKLSGPVSTMMACPDGKKEKKFVTAGLGDDAMLRYNSKLPI
CCCCCCCEECCCCCEEEEEEECCCCHHHEEECCCCCCCCEEEEECCCCCEEEEECCCCCE
VVYTPSNVDVKYRIWRADETIGNAVVR
EEECCCCCCEEEEEEECCCCCCHHHCC
>Mature Secondary Structure 
SAGALAADQPLEKVAPFPKAEKGMKRQVIQLPQQQDESALKVELMIGQTLEVDCNHHRL
CCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCEEEECCCCCCC
GGELESKTLEGWGYDYYVFEKLSGPVSTMMACPDGKKEKKFVTAGLGDDAMLRYNSKLPI
CCCCCCCEECCCCCEEEEEEECCCCHHHEEECCCCCCCCEEEEECCCCCEEEEECCCCCE
VVYTPSNVDVKYRIWRADETIGNAVVR
EEECCCCCCEEEEEEECCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA