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The map label for this gene is udk [H]

Identifier: 238895638

GI number: 238895638

Start: 3552103

End: 3552810

Strand: Reverse

Name: udk [H]

Synonym: KP1_3730

Alternate gene names: 238895638

Gene position: 3552810-3552103 (Counterclockwise)

Preceding gene: 238895639

Following gene: 238895637

Centisome position: 67.69

GC content: 52.4

Gene sequence:

>708_bases
TTGCCGCGTTTGGCGGTCCGCCGCCACCCTCCATCTCTATCCAGGTTAATCAGGTCGCAAAAATTTATGACTGATATGTC
CCATCAGTGCGTCATTGTAGGCATCGCCGGCGCATCGGCTTCTGGCAAAAGTCTTATCGCCAGTACTCTCTATCGCGAAT
TGCGTGAACAAGTTGGCGACGAACATATTGGCGTCATTCCGGAAGACAGCTATTACAAAGATCAAAGCCATCTGTCGATG
GAAGAGCGCGTCAAAACCAACTATGACCACCCGAGCTCAATGGACCACAGTCTGTTGTTCCAGCATTTGCAGATGCTGAA
AAGCGGCCAGCCGATTGAACTGCCGGTCTATAGCTACGTCGAGCATACCCGCACGCCGAACACCATTCACGTCGAGCCGA
AGAAGGTGATTATCCTTGAAGGGATCCTGCTGCTGACCGATGCGCGCCTGCGTAACGAGCTCAACTTCTCTATTTTCGTC
GACACCCCTCTCGATATTTGCCTGATGCGCCGTATTAAGCGCGACGTTAACGAGCGCGGCCGCTCCATGGACTCGGTGAT
GGCCCAGTATCAGAAAACCGTGCGCCCGATGTTCCTGCAGTTTATTGAACCGTCGAAGCAGTATGCCGACATCATCGTGC
CGCGCGGCGGCAAAAACCGCATCGCTATTGATATTCTGAAGGCCAAAATCAGTCAGTTCTTTGAATAA

Upstream 100 bases:

>100_bases
CGCGCTGTTGCATATCTGGTATACCGATGACTGGGCGCCGGCGGCGGAATAGCCGCCCGGGGCGCATACCACTGGTATCG
GGACGCTGAAATCCCTATAA

Downstream 100 bases:

>100_bases
CCTGGCCGAATTGTGTAACGTGCAAAGAGTAGCCCTGTTGCCCTCTCCGCCGCGAAGCGTGCGGGAAGCAGCCTTATAAG
GAGAAAGCCCATGCGTCTGT

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MPRLAVRRHPPSLSRLIRSQKFMTDMSHQCVIVGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDSYYKDQSHLSM
EERVKTNYDHPSSMDHSLLFQHLQMLKSGQPIELPVYSYVEHTRTPNTIHVEPKKVIILEGILLLTDARLRNELNFSIFV
DTPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE

Sequences:

>Translated_235_residues
MPRLAVRRHPPSLSRLIRSQKFMTDMSHQCVIVGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDSYYKDQSHLSM
EERVKTNYDHPSSMDHSLLFQHLQMLKSGQPIELPVYSYVEHTRTPNTIHVEPKKVIILEGILLLTDARLRNELNFSIFV
DTPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
>Mature_234_residues
PRLAVRRHPPSLSRLIRSQKFMTDMSHQCVIVGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDSYYKDQSHLSME
ERVKTNYDHPSSMDHSLLFQHLQMLKSGQPIELPVYSYVEHTRTPNTIHVEPKKVIILEGILLLTDARLRNELNFSIFVD
TPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI18699734, Length=203, Percent_Identity=34.4827586206897, Blast_Score=152, Evalue=2e-37,
Organism=Homo sapiens, GI301129207, Length=202, Percent_Identity=37.6237623762376, Blast_Score=151, Evalue=6e-37,
Organism=Homo sapiens, GI57863312, Length=202, Percent_Identity=37.6237623762376, Blast_Score=151, Evalue=6e-37,
Organism=Homo sapiens, GI13899253, Length=212, Percent_Identity=34.4339622641509, Blast_Score=142, Evalue=2e-34,
Organism=Homo sapiens, GI209863022, Length=150, Percent_Identity=31.3333333333333, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI87082034, Length=213, Percent_Identity=92.018779342723, Blast_Score=408, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17539892, Length=207, Percent_Identity=37.6811594202899, Blast_Score=157, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17539894, Length=207, Percent_Identity=37.6811594202899, Blast_Score=157, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI71981181, Length=216, Percent_Identity=33.3333333333333, Blast_Score=126, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6324339, Length=177, Percent_Identity=32.7683615819209, Blast_Score=115, Evalue=7e-27,
Organism=Drosophila melanogaster, GI221458995, Length=211, Percent_Identity=35.0710900473934, Blast_Score=148, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24649624, Length=210, Percent_Identity=34.7619047619048, Blast_Score=147, Evalue=5e-36,
Organism=Drosophila melanogaster, GI28573516, Length=197, Percent_Identity=38.0710659898477, Blast_Score=143, Evalue=8e-35,
Organism=Drosophila melanogaster, GI28573514, Length=197, Percent_Identity=38.0710659898477, Blast_Score=143, Evalue=8e-35,
Organism=Drosophila melanogaster, GI28573512, Length=197, Percent_Identity=38.0710659898477, Blast_Score=143, Evalue=8e-35,
Organism=Drosophila melanogaster, GI45550449, Length=197, Percent_Identity=38.0710659898477, Blast_Score=143, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 27049; Mature: 26918

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLAVRRHPPSLSRLIRSQKFMTDMSHQCVIVGIAGASASGKSLIASTLYRELREQVGD
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCC
EHIGVIPEDSYYKDQSHLSMEERVKTNYDHPSSMDHSLLFQHLQMLKSGQPIELPVYSYV
CCCCCCCCCCCCCCHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHH
EHTRTPNTIHVEPKKVIILEGILLLTDARLRNELNFSIFVDTPLDICLMRRIKRDVNERG
HHCCCCCEEEECCCEEEEEHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHC
RSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PRLAVRRHPPSLSRLIRSQKFMTDMSHQCVIVGIAGASASGKSLIASTLYRELREQVGD
CCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCC
EHIGVIPEDSYYKDQSHLSMEERVKTNYDHPSSMDHSLLFQHLQMLKSGQPIELPVYSYV
CCCCCCCCCCCCCCHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHH
EHTRTPNTIHVEPKKVIILEGILLLTDARLRNELNFSIFVDTPLDICLMRRIKRDVNERG
HHCCCCCEEEECCCEEEEEHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHC
RSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]