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The map label for this gene is yegH [H]

Identifier: 238895635

GI number: 238895635

Start: 3547261

End: 3548913

Strand: Direct

Name: yegH [H]

Synonym: KP1_3727

Alternate gene names: 238895635

Gene position: 3547261-3548913 (Clockwise)

Preceding gene: 238895614

Following gene: 238895640

Centisome position: 67.59

GC content: 56.62

Gene sequence:

>1653_bases
TTGCATTTTAGACTCATCTTATCCATGATCGTGGTAACACATACCGCAGTCGTACAGGTTTTAATACATATGGAATGGAT
TGCCGATCCGTCAATCTGGGCAGGTCTCGTCACGCTGGTGGTTATCGAACTGGTGTTGGGTATCGATAACCTGGTCTTTA
TCGCTATCCTCGCCGAGAAGCTCCCTCCCGCCCAGCGCGACCGCGCGCGGATCACTGGCCTGATGCTGGCGATGGTCATG
CGTCTTCTGCTGCTGGCCTCTATCTCCTGGCTGGTCACCCTGACCAAACCGCTGATTGTTTTTCACGACTTCAGCTTTAG
CGCCCGCGATTTAATTATGCTGTTTGGCGGCCTGTTTCTGCTGTTTAAAGCGACCGTCGAGCTTAATGAGCGGCTGGAGG
GGAAAGACAGCGATAACCCCACCCAGCGCAAAGGGGCGAAATTCTGGGCCGTCGTGGCGCAGATCGTGGTGCTCGACGCC
ATCTTCTCGCTCGACTCGGTGATCACCGCCGTCGGCATGGTTGATCACCTGGCGGTGATGATGGCCGCGGTGGTTATCGC
CATCAGCCTGATGCTGATGGCCAGCAAGGCGCTGACGCGCTTCGTTAACAGCCACCCGACCATCGTGATCCTCTGTCTGA
GCTTCCTGCTGATGATCGGCTTCAGTCTGATTGCTGAAGGCTTCAGCTTTATTATTCCGAAAGGCTATCTATATGCGGCC
ATTGGCTTCTCGGTCATGATTGAAGCCCTTAACCAGCTGGCGCAGTTTAACCGCCGTCGCTTCCTCTCCGCCAATATGAC
GCTGCGTCAGCGCACTACCGAAGCGGTGATGAATCTGCTGAGCGGGCAGAAAGAAAAAGCTGAACTGGATGCTGACACGG
CGTCGCTGGTCGCCGATCAGGATCAACATCCTCTGTTTAATCCGCAGGAACGACTGATGATTGAGCGGGTGCTGAACCTT
AATCAGCGCAGCGTCAGCAGTATTATGACGTCGCGCCATGATATCGAGCGCATCAACCTCAGCGCGCCGGAGGAAGAGAT
CCGCAGCCTGGTGGAGAAAAATCAGCATACCCGTCTGGTGGTCACCGGCGGGAAAGATAATGAAGATCTGCTGGGGGTGG
TGCATGTTATTGACCTGCTCCAGCAGTCCCTGCGTCAGGAGCCGCTGGATCTGCAGGCGCTGGTGCGTCAACCGCTGGTC
TTTCCGGAGGGGCTGCCGCTCCTCTCGGCGCTCGAGCAGTTCCGCCAGGCCCGCACCCATTTTGCCTTTGTGGTCGATGA
GTTTGGTTCCGTCGAGGGGATTGTGACCCTCAGCGACGTGATGGAGACCATCGCCGGTAATCTGCCCAATGAGGTGGAGG
AGATCGATGCCCGGCACGATATTCAGCATCATCAGGACGGCTCATGGACGGTTAACGGCCATATGCCGCTGGAGGATCTG
GTGCAGTACGTTCCGCTGCCGCTGGATGATAAACGGGAGTACCACACCGTCGCCGGTCTGCTGATGGAGTATCTGCAGCA
TGTGCCGCAGGTGGGGGAAACCATTGAGATTGACGGCTATACCCTGCGCACGCTGCAGGTTGACAGCCATCGGGTGCAGA
AGGTGCAGATCGTCCCGCCGGTAAAGCAGGATGAGCTGGATTATGAGGTGTAA

Upstream 100 bases:

>100_bases
GTTATTTTTTCACTGTTCTTTTCCGGAACAAAATTCTTATCGGTTCGCTTAATCCGCTGGAAATATATCCATCCACGGCA
GGGCGATATCCGCGTCGTTA

Downstream 100 bases:

>100_bases
TCGTCAGGCATAAAACGGCCCGGGGTATCCCGGGCCGTAAAATTGATAGCCAGATATCCTGTTTAATGCCTGATGGCGCT
TCGCTTATCAGGCCTACGGG

Product: putative transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MHFRLILSMIVVTHTAVVQVLIHMEWIADPSIWAGLVTLVVIELVLGIDNLVFIAILAEKLPPAQRDRARITGLMLAMVM
RLLLLASISWLVTLTKPLIVFHDFSFSARDLIMLFGGLFLLFKATVELNERLEGKDSDNPTQRKGAKFWAVVAQIVVLDA
IFSLDSVITAVGMVDHLAVMMAAVVIAISLMLMASKALTRFVNSHPTIVILCLSFLLMIGFSLIAEGFSFIIPKGYLYAA
IGFSVMIEALNQLAQFNRRRFLSANMTLRQRTTEAVMNLLSGQKEKAELDADTASLVADQDQHPLFNPQERLMIERVLNL
NQRSVSSIMTSRHDIERINLSAPEEEIRSLVEKNQHTRLVVTGGKDNEDLLGVVHVIDLLQQSLRQEPLDLQALVRQPLV
FPEGLPLLSALEQFRQARTHFAFVVDEFGSVEGIVTLSDVMETIAGNLPNEVEEIDARHDIQHHQDGSWTVNGHMPLEDL
VQYVPLPLDDKREYHTVAGLLMEYLQHVPQVGETIEIDGYTLRTLQVDSHRVQKVQIVPPVKQDELDYEV

Sequences:

>Translated_550_residues
MHFRLILSMIVVTHTAVVQVLIHMEWIADPSIWAGLVTLVVIELVLGIDNLVFIAILAEKLPPAQRDRARITGLMLAMVM
RLLLLASISWLVTLTKPLIVFHDFSFSARDLIMLFGGLFLLFKATVELNERLEGKDSDNPTQRKGAKFWAVVAQIVVLDA
IFSLDSVITAVGMVDHLAVMMAAVVIAISLMLMASKALTRFVNSHPTIVILCLSFLLMIGFSLIAEGFSFIIPKGYLYAA
IGFSVMIEALNQLAQFNRRRFLSANMTLRQRTTEAVMNLLSGQKEKAELDADTASLVADQDQHPLFNPQERLMIERVLNL
NQRSVSSIMTSRHDIERINLSAPEEEIRSLVEKNQHTRLVVTGGKDNEDLLGVVHVIDLLQQSLRQEPLDLQALVRQPLV
FPEGLPLLSALEQFRQARTHFAFVVDEFGSVEGIVTLSDVMETIAGNLPNEVEEIDARHDIQHHQDGSWTVNGHMPLEDL
VQYVPLPLDDKREYHTVAGLLMEYLQHVPQVGETIEIDGYTLRTLQVDSHRVQKVQIVPPVKQDELDYEV
>Mature_550_residues
MHFRLILSMIVVTHTAVVQVLIHMEWIADPSIWAGLVTLVVIELVLGIDNLVFIAILAEKLPPAQRDRARITGLMLAMVM
RLLLLASISWLVTLTKPLIVFHDFSFSARDLIMLFGGLFLLFKATVELNERLEGKDSDNPTQRKGAKFWAVVAQIVVLDA
IFSLDSVITAVGMVDHLAVMMAAVVIAISLMLMASKALTRFVNSHPTIVILCLSFLLMIGFSLIAEGFSFIIPKGYLYAA
IGFSVMIEALNQLAQFNRRRFLSANMTLRQRTTEAVMNLLSGQKEKAELDADTASLVADQDQHPLFNPQERLMIERVLNL
NQRSVSSIMTSRHDIERINLSAPEEEIRSLVEKNQHTRLVVTGGKDNEDLLGVVHVIDLLQQSLRQEPLDLQALVRQPLV
FPEGLPLLSALEQFRQARTHFAFVVDEFGSVEGIVTLSDVMETIAGNLPNEVEEIDARHDIQHHQDGSWTVNGHMPLEDL
VQYVPLPLDDKREYHTVAGLLMEYLQHVPQVGETIEIDGYTLRTLQVDSHRVQKVQIVPPVKQDELDYEV

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=338, Percent_Identity=21.301775147929, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI87082033, Length=527, Percent_Identity=84.2504743833017, Blast_Score=886, Evalue=0.0,
Organism=Escherichia coli, GI1788119, Length=528, Percent_Identity=49.8106060606061, Blast_Score=457, Evalue=1e-129,
Organism=Escherichia coli, GI1789197, Length=226, Percent_Identity=51.7699115044248, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1790664, Length=232, Percent_Identity=30.1724137931034, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1786879, Length=254, Percent_Identity=30.3149606299213, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI145693175, Length=233, Percent_Identity=25.3218884120172, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005496
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF03741 TerC [H]

EC number: NA

Molecular weight: Translated: 61744; Mature: 61744

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFRLILSMIVVTHTAVVQVLIHMEWIADPSIWAGLVTLVVIELVLGIDNLVFIAILAEK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPPAQRDRARITGLMLAMVMRLLLLASISWLVTLTKPLIVFHDFSFSARDLIMLFGGLFL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHH
LFKATVELNERLEGKDSDNPTQRKGAKFWAVVAQIVVLDAIFSLDSVITAVGMVDHLAVM
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAAVVIAISLMLMASKALTRFVNSHPTIVILCLSFLLMIGFSLIAEGFSFIIPKGYLYAA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHH
IGFSVMIEALNQLAQFNRRRFLSANMTLRQRTTEAVMNLLSGQKEKAELDADTASLVADQ
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHCCC
DQHPLFNPQERLMIERVLNLNQRSVSSIMTSRHDIERINLSAPEEEIRSLVEKNQHTRLV
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEE
VTGGKDNEDLLGVVHVIDLLQQSLRQEPLDLQALVRQPLVFPEGLPLLSALEQFRQARTH
EECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
FAFVVDEFGSVEGIVTLSDVMETIAGNLPNEVEEIDARHDIQHHQDGSWTVNGHMPLEDL
HHHHHHHCCCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHH
VQYVPLPLDDKREYHTVAGLLMEYLQHVPQVGETIEIDGYTLRTLQVDSHRVQKVQIVPP
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEECCHHCEEEEECCC
VKQDELDYEV
CCCCCCCCCC
>Mature Secondary Structure
MHFRLILSMIVVTHTAVVQVLIHMEWIADPSIWAGLVTLVVIELVLGIDNLVFIAILAEK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPPAQRDRARITGLMLAMVMRLLLLASISWLVTLTKPLIVFHDFSFSARDLIMLFGGLFL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHH
LFKATVELNERLEGKDSDNPTQRKGAKFWAVVAQIVVLDAIFSLDSVITAVGMVDHLAVM
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAAVVIAISLMLMASKALTRFVNSHPTIVILCLSFLLMIGFSLIAEGFSFIIPKGYLYAA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHH
IGFSVMIEALNQLAQFNRRRFLSANMTLRQRTTEAVMNLLSGQKEKAELDADTASLVADQ
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHCCC
DQHPLFNPQERLMIERVLNLNQRSVSSIMTSRHDIERINLSAPEEEIRSLVEKNQHTRLV
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEE
VTGGKDNEDLLGVVHVIDLLQQSLRQEPLDLQALVRQPLVFPEGLPLLSALEQFRQARTH
EECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
FAFVVDEFGSVEGIVTLSDVMETIAGNLPNEVEEIDARHDIQHHQDGSWTVNGHMPLEDL
HHHHHHHCCCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHH
VQYVPLPLDDKREYHTVAGLLMEYLQHVPQVGETIEIDGYTLRTLQVDSHRVQKVQIVPP
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEECCHHCEEEEECCC
VKQDELDYEV
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]