Click here to switch to the map view.

The map label for this gene is cobT [H]

Identifier: 238895584

GI number: 238895584

Start: 3486495

End: 3487562

Strand: Reverse

Name: cobT [H]

Synonym: KP1_3667

Alternate gene names: 238895584

Gene position: 3487562-3486495 (Counterclockwise)

Preceding gene: 238895585

Following gene: 238895582

Centisome position: 66.45

GC content: 66.76

Gene sequence:

>1068_bases
ATGGAAACACTTTCGGCGTTACTGGCTGCCATTCCGCAGCCCGATGTGGCGGCCATGGCGCGCGCTCAGCAGCATATTGA
TGGCCTGTTAAAGCCGCCCGGCAGCCTTGGCCGTCTGGAGACGCTGGCGGTGCAGCTGGCCGGTCTGCCTGGCTTGCAGG
GGCAGCTGGCGCTGGCGGAGAAAGCGATTGTGGTCATGTGCGCCGACCATGGCGTCTGGCATGAAGGCGTGACCCCTTCG
CCGCAGGGGGTGACGGCCATTCATGCCGGCAATATGGTGCGGGGCAACACCGGCGTCTGCGTGCTGGCGGCGCAGGCCGG
GGCCAGGGTGCAGGTAGTGGATGTCGGCATCGATGCCGACCCGCTGCCGGGCCTGATTAACCTCAAAGTGGCCCGCGGTA
GCGGGAATATCGCCCGGACGGCGGCGATGAGCCGCCAGCAGGCGGAGACGGTGCTGCTGGCCAGCATGCATCTCACCCGC
CAGCTCGCTGCCGACGGGGTGAAAGCCTTCGGCGTCGGCGAATTGGGAATGGCCAATACCACCCCGGCCGCAGCGACGAT
CAGTGTCCTGACGGGCAGCGACCCTGACGCGGTGGTGGGCTGTGGGGCTAATCTGCCGCTGGCGCAGCGGGGCCATAAGG
TGGCGGTGGTGCGCCAGGCGATAGCCCATAATCAGCCGAACCCGGCCGACGGGCTGGATGTCCTGGCGAAGGTGGGGGGT
TACGATCTGGTGGGCATGACCGGGGTGATCCTCGGGGCGGCCTCCTGTGGCCTGCCGGTGGTGCTGGATGGCTTCCTCTC
CTATGCCTCTGCCCTGGCCGCCTGCCGCATGGCCCCGTCGGCGCACCCTTATCTTATTCCTTCACACCTGTCGGCGGAGA
AAGGAGCGCAGATCGCCCTCGACGCGCTGGGTCTGCGGCCGTATCTCGATATGGACATGCGCCTGGGAGAGGGCAGCGGC
GCCGCGCTGGCGATGCACCTGTTGGATGCCGCCAGCGTGATGTACAACCAGATGGGAACGCTGGCGCAGAGCAATATTGT
GTTGCCCGATAGCGCGCCGTCATCCTGA

Upstream 100 bases:

>100_bases
CGGGCAGACCGGGGATACCCTCGGGGCGGCGATTGAGCTGGGCGAATTACTCTTTTTACTGGCGCTGCTGTAAGGCCTGA
CGCCAACGGTGGGGAACAGA

Downstream 100 bases:

>100_bases
TGGTAAAGCGCATCGTCCCGCGATGGGGGCGATGCGCCGGGTTTACAGGGCCTGCTGCCAGACCGCCTGGGGCAGGAGAT
AAACCTTCGCCGGGGCGCGC

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
METLSALLAAIPQPDVAAMARAQQHIDGLLKPPGSLGRLETLAVQLAGLPGLQGQLALAEKAIVVMCADHGVWHEGVTPS
PQGVTAIHAGNMVRGNTGVCVLAAQAGARVQVVDVGIDADPLPGLINLKVARGSGNIARTAAMSRQQAETVLLASMHLTR
QLAADGVKAFGVGELGMANTTPAAATISVLTGSDPDAVVGCGANLPLAQRGHKVAVVRQAIAHNQPNPADGLDVLAKVGG
YDLVGMTGVILGAASCGLPVVLDGFLSYASALAACRMAPSAHPYLIPSHLSAEKGAQIALDALGLRPYLDMDMRLGEGSG
AALAMHLLDAASVMYNQMGTLAQSNIVLPDSAPSS

Sequences:

>Translated_355_residues
METLSALLAAIPQPDVAAMARAQQHIDGLLKPPGSLGRLETLAVQLAGLPGLQGQLALAEKAIVVMCADHGVWHEGVTPS
PQGVTAIHAGNMVRGNTGVCVLAAQAGARVQVVDVGIDADPLPGLINLKVARGSGNIARTAAMSRQQAETVLLASMHLTR
QLAADGVKAFGVGELGMANTTPAAATISVLTGSDPDAVVGCGANLPLAQRGHKVAVVRQAIAHNQPNPADGLDVLAKVGG
YDLVGMTGVILGAASCGLPVVLDGFLSYASALAACRMAPSAHPYLIPSHLSAEKGAQIALDALGLRPYLDMDMRLGEGSG
AALAMHLLDAASVMYNQMGTLAQSNIVLPDSAPSS
>Mature_355_residues
METLSALLAAIPQPDVAAMARAQQHIDGLLKPPGSLGRLETLAVQLAGLPGLQGQLALAEKAIVVMCADHGVWHEGVTPS
PQGVTAIHAGNMVRGNTGVCVLAAQAGARVQVVDVGIDADPLPGLINLKVARGSGNIARTAAMSRQQAETVLLASMHLTR
QLAADGVKAFGVGELGMANTTPAAATISVLTGSDPDAVVGCGANLPLAQRGHKVAVVRQAIAHNQPNPADGLDVLAKVGG
YDLVGMTGVILGAASCGLPVVLDGFLSYASALAACRMAPSAHPYLIPSHLSAEKGAQIALDALGLRPYLDMDMRLGEGSG
AALAMHLLDAASVMYNQMGTLAQSNIVLPDSAPSS

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=355, Percent_Identity=68.169014084507, Blast_Score=479, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 35940; Mature: 35940

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METLSALLAAIPQPDVAAMARAQQHIDGLLKPPGSLGRLETLAVQLAGLPGLQGQLALAE
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEC
KAIVVMCADHGVWHEGVTPSPQGVTAIHAGNMVRGNTGVCVLAAQAGARVQVVDVGIDAD
CEEEEEEECCCCCCCCCCCCCCCEEEEECCCEEECCCCEEEEEECCCCEEEEEEECCCCC
PLPGLINLKVARGSGNIARTAAMSRQQAETVLLASMHLTRQLAADGVKAFGVGELGMANT
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCC
TPAAATISVLTGSDPDAVVGCGANLPLAQRGHKVAVVRQAIAHNQPNPADGLDVLAKVGG
CCCCEEEEEEECCCCCEEEECCCCCCHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCC
YDLVGMTGVILGAASCGLPVVLDGFLSYASALAACRMAPSAHPYLIPSHLSAEKGAQIAL
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEE
DALGLRPYLDMDMRLGEGSGAALAMHLLDAASVMYNQMGTLAQSNIVLPDSAPSS
EHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCC
>Mature Secondary Structure
METLSALLAAIPQPDVAAMARAQQHIDGLLKPPGSLGRLETLAVQLAGLPGLQGQLALAE
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEC
KAIVVMCADHGVWHEGVTPSPQGVTAIHAGNMVRGNTGVCVLAAQAGARVQVVDVGIDAD
CEEEEEEECCCCCCCCCCCCCCCEEEEECCCEEECCCCEEEEEECCCCEEEEEEECCCCC
PLPGLINLKVARGSGNIARTAAMSRQQAETVLLASMHLTRQLAADGVKAFGVGELGMANT
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCC
TPAAATISVLTGSDPDAVVGCGANLPLAQRGHKVAVVRQAIAHNQPNPADGLDVLAKVGG
CCCCEEEEEEECCCCCEEEECCCCCCHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCC
YDLVGMTGVILGAASCGLPVVLDGFLSYASALAACRMAPSAHPYLIPSHLSAEKGAQIAL
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEE
DALGLRPYLDMDMRLGEGSGAALAMHLLDAASVMYNQMGTLAQSNIVLPDSAPSS
EHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA