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The map label for this gene is yoaE [H]

Identifier: 238895391

GI number: 238895391

Start: 3277996

End: 3279555

Strand: Reverse

Name: yoaE [H]

Synonym: KP1_3457

Alternate gene names: 238895391

Gene position: 3279555-3277996 (Counterclockwise)

Preceding gene: 238895397

Following gene: 238895386

Centisome position: 62.49

GC content: 59.42

Gene sequence:

>1560_bases
ATGGAATTGTTAATGGATCCCTCAATCTGGGCCGGCCTGTTGACGCTTATCGTTCTGGAAATTGTGCTCGGTATCGACAA
CCTGGTGTTTATTGCCATCCTGGCGGACAAACTGCCGCCGAAGCAGCGCGATAAAGCGCGTCTGATCGGCCTGTCACTGG
CGCTGGTGATGCGCCTGGGGCTGCTGTCGGTCATCTCCTGGATGGTGACGCTGACGAAACCACTGATTACCATCGCCGAT
TTCTCCTTTTCCGGGCGCGATCTCATCATGCTGCTCGGCGGGATCTTCTTGTTGTTTAAGGCGACAACCGAGCTGCATGA
ACGGCTGGAAAACCGCCAGCACGATGCCGGTCACGGTAAAGGCTATGCCAGTTTCTGGGTAGTAGTATTGCAGATAGTGG
TGCTGGATGCCGTCTTCTCCCTGGACGCCGTGATCACGGCGGTCGGGATGGTTAACCATCTGCCGGTGATGATGGCGGCG
GTGGTGATCGCGATGATCTTGATGCTGCTGGCCTCCAAGCCGTTGACGCGCTTTGTCAACCAGCACCCGACGGTGGTCGT
GCTCTGTCTGAGCTTCCTGTTGATGATTGGCCTTAGCCTGGTGGCGGAAGGGTTTGGCTTCCATATTCCAAAAGGGTATC
TGTACGCGGCGATCGGTTTCTCGATCATTATCGAGTTCTTTAACCAGGTGGCGCGCCGTAACTTTGTTCGCCACCAGTCG
ACGCTGCCGCTGCGCGCTCGGACCGCGGATGCCATCCTGCGCCTGATGGGCGGCCGCAAACAGGCCTCCGTCAGCCATGA
CGCAGACAGTCCAGCCGCGGTGCCCGTTCCTGAGGGCGCCTTTGCGGAAGAAGAGCGCTACATGATTAACGGCGTGCTGA
CCCTGGCCCAGCGCTCCCTGCGCAGCATCATGACCCCGCGCGGAGAAATCAGCTGGGTCGACGCTGAGCAGAGTGAAGAT
GAAATTCGTCGTCAGCTGCTGTCGTCGCCGCACAGCCTCTTCCCGGTCTGCCGCGGAGAGCTGGATGAAATCATTGGTAT
CGTGCGGGCGAAAGAGATGCTGGTGGCCCTGGAGTCGGGGGAAAACGTCGCGGCGCTGGCTTCTGCCTCCCCGGCAATTG
TCGTTCCGGAAACGCTGGACCCGATCAATCTGCTCGGGGTCCTGCGTCGGGCGCGCGGCAGCTTCGTCATCGTAACTAAT
GAATTTGGCGTGGTGCAGGGGCTGGTCACGCCGCTGGACGTCCTTGAAGCCATCGCCGGTGAATTCCCGGACGCTGATGA
GACGCCAGAGATTGTCATCGATGGCGATGGCTGGCTTATTAAGGGGTCGACCGACCTGCATGCGCTGCAGCAGGCGCTGG
GGCTGGATCCACTGATCAATGACGATGAGGATATTGCCACCGTTGCCGGGCTGGTGATCTCCGCCAATGGTCATATCCCG
CGCATTGGCGACGTCGTGTCGCTTCCGCCGCTGCATTTTACCGTAGTGGAAGCGAATGATTACCGGGTCGATCTGGTGCG
CGCGGTGGTCACTCGTCCGCCGAGCGACGAAGAAGAGTAA

Upstream 100 bases:

>100_bases
TGATTGCCACCTCTACGTATCCCGCATTTCTTTCAGCACCTGGTGTCGCGCCCCTGCATGGCATGGCGATGACTGACCTT
GCCGCAAACCGGAGTCGTAC

Downstream 100 bases:

>100_bases
TCGCCAGGCTCGCCGGCCGCTGCGGCCGGCGAGTTATTCTGTCGTCTCGCTCTCACCCTCACTCTCACTCTCCTCCCTGC
TGGCCAGCCACGCCGGGAAC

Product: putative transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MELLMDPSIWAGLLTLIVLEIVLGIDNLVFIAILADKLPPKQRDKARLIGLSLALVMRLGLLSVISWMVTLTKPLITIAD
FSFSGRDLIMLLGGIFLLFKATTELHERLENRQHDAGHGKGYASFWVVVLQIVVLDAVFSLDAVITAVGMVNHLPVMMAA
VVIAMILMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAIGFSIIIEFFNQVARRNFVRHQS
TLPLRARTADAILRLMGGRKQASVSHDADSPAAVPVPEGAFAEEERYMINGVLTLAQRSLRSIMTPRGEISWVDAEQSED
EIRRQLLSSPHSLFPVCRGELDEIIGIVRAKEMLVALESGENVAALASASPAIVVPETLDPINLLGVLRRARGSFVIVTN
EFGVVQGLVTPLDVLEAIAGEFPDADETPEIVIDGDGWLIKGSTDLHALQQALGLDPLINDDEDIATVAGLVISANGHIP
RIGDVVSLPPLHFTVVEANDYRVDLVRAVVTRPPSDEEE

Sequences:

>Translated_519_residues
MELLMDPSIWAGLLTLIVLEIVLGIDNLVFIAILADKLPPKQRDKARLIGLSLALVMRLGLLSVISWMVTLTKPLITIAD
FSFSGRDLIMLLGGIFLLFKATTELHERLENRQHDAGHGKGYASFWVVVLQIVVLDAVFSLDAVITAVGMVNHLPVMMAA
VVIAMILMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAIGFSIIIEFFNQVARRNFVRHQS
TLPLRARTADAILRLMGGRKQASVSHDADSPAAVPVPEGAFAEEERYMINGVLTLAQRSLRSIMTPRGEISWVDAEQSED
EIRRQLLSSPHSLFPVCRGELDEIIGIVRAKEMLVALESGENVAALASASPAIVVPETLDPINLLGVLRRARGSFVIVTN
EFGVVQGLVTPLDVLEAIAGEFPDADETPEIVIDGDGWLIKGSTDLHALQQALGLDPLINDDEDIATVAGLVISANGHIP
RIGDVVSLPPLHFTVVEANDYRVDLVRAVVTRPPSDEEE
>Mature_519_residues
MELLMDPSIWAGLLTLIVLEIVLGIDNLVFIAILADKLPPKQRDKARLIGLSLALVMRLGLLSVISWMVTLTKPLITIAD
FSFSGRDLIMLLGGIFLLFKATTELHERLENRQHDAGHGKGYASFWVVVLQIVVLDAVFSLDAVITAVGMVNHLPVMMAA
VVIAMILMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAIGFSIIIEFFNQVARRNFVRHQS
TLPLRARTADAILRLMGGRKQASVSHDADSPAAVPVPEGAFAEEERYMINGVLTLAQRSLRSIMTPRGEISWVDAEQSED
EIRRQLLSSPHSLFPVCRGELDEIIGIVRAKEMLVALESGENVAALASASPAIVVPETLDPINLLGVLRRARGSFVIVTN
EFGVVQGLVTPLDVLEAIAGEFPDADETPEIVIDGDGWLIKGSTDLHALQQALGLDPLINDDEDIATVAGLVISANGHIP
RIGDVVSLPPLHFTVVEANDYRVDLVRAVVTRPPSDEEE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=241, Percent_Identity=23.2365145228216, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788119, Length=519, Percent_Identity=87.2832369942196, Blast_Score=897, Evalue=0.0,
Organism=Escherichia coli, GI87082033, Length=530, Percent_Identity=50.377358490566, Blast_Score=438, Evalue=1e-124,
Organism=Escherichia coli, GI1789197, Length=229, Percent_Identity=48.9082969432314, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1790664, Length=267, Percent_Identity=28.0898876404494, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1786879, Length=226, Percent_Identity=31.4159292035398, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI145693175, Length=273, Percent_Identity=26.007326007326, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005496
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF03741 TerC [H]

EC number: NA

Molecular weight: Translated: 56455; Mature: 56455

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]