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The map label for this gene is pabB [H]

Identifier: 238895387

GI number: 238895387

Start: 3272663

End: 3274087

Strand: Direct

Name: pabB [H]

Synonym: KP1_3453

Alternate gene names: 238895387

Gene position: 3272663-3274087 (Clockwise)

Preceding gene: 238895385

Following gene: 238895388

Centisome position: 62.35

GC content: 61.75

Gene sequence:

>1425_bases
GTGGGGCGTAATTATTTCACGCCGTCCCCAACTACGCCAGAGGGGCGGCAACGTTCAGGATCGAGAAAGATGTTGTCCCC
CGCGATTATTACCCTGCCCTGGCGCCCGGATGCGGCCGAACACTATTTTGCGCCGTTAAGCGCCCTGCCCTGGGCGATGC
TGCTGCATTCCGGCTTTGCCGACCATCCGCATAACCGCTTTGATATTCTGGTGGCTGCCCCGCGCGCCACGCTGCTGACG
CGCGGTGAACAGACGTGGGTCGACGACGGCGAAACCGTTGTTGTCTCAGCGGAAGATCCGCTGCAGCTCCTGCAGCAGCA
GTTGGATCGTCAGCCGTTCACGCCGCAGCCCCATGACGATCTGCCGTTTCTCGGCGGCGCGCTGGGATTATTCGGTTACG
ACCTGGGCCGTCGCTTTGAGCGTCTCCCTTCGCACGCGCAGGCCGATATCGCGCTGGCGGATATGGCGGTGGGGATCTAT
GACTGGGCGCTTATCGTCGACCACCAGCGCCAACAGATATCGCTGCTCAGCTATGACGACCCGCAGCAGCGTCTACAGTG
GCTGGAGGCGCAAACGCCGACGCCGGGTGAAACCTTCGCCCTGAGCTCTGCCTGGCAGTCAAATATGAGCCGCCAGCAGT
ACGGGGAAAAATTTCGCCAGGTACAGGCCTATCTGCACAGCGGCGACTGCTATCAGGTCAACCTCGCCCAGCGTTTTCAG
GCCAGCTACGTCGGTGATGAATGGCAGGCCTTCCGCCAGCTGAACGCCGTCAACCGCGCCCCCTTTAGCGCCTTTATTCG
CCTCGATGAAGGGGCGATTTTAAGCCTGTCGCCGGAGCGCTTTATCCAGCTGCGCCAGGGGGAGATCCAGACGCGGCCGA
TAAAAGGCACCCTGCCGCGGCTCGATTCGCCGCTGGCAGATGCGCAGCAGGCTGAGAAGCTGGCGAATTCGCCGAAAGAT
CGCGCCGAGAATTTAATGATTGTCGACCTGATGCGCAACGACATCGGCCGCGTCGCCGTCCCGGGCAGCGTGCGGGTCCC
CGAGCTGTTCGTGGTGGAGCCGTTCCCGGCGGTCCATCATCTGGTCAGCACCATCACCGCCCGCCTGCCAATGACGCTGC
ACGCCAGCGACCTGCTGCGCGCCGCCTTTCCCGGCGGCTCGATCACCGGCGCGCCGAAAGTGCGGGCGATGGAGATTATC
GATGAACTGGAGCCCCAGCGACGCAATGCCTGGTGTGGGAGCATTGGCTACCTGAGCTATTGCGGCAATATGGATACCAG
CATCACCATTCGCACCCTGACGGCATGGCAGGGACAGCTGTACTGCTCCGCCGGCGGCGGAATTGTGGCGGATAGCGAGG
AAGCGGCGGAATATCAGGAAACTTTTGATAAAGTTAATCGTATCCTGCAGCAACTGGAGAACTAG

Upstream 100 bases:

>100_bases
CCCCTGAGCCATTAGCTCATGGATACGTTCGACCGCTTTTTGCTGTTGCTCGTGGCTCAGCGAAGGTAAACCTGCAAACA
TCTTTTACTCCTGCTACATT

Downstream 100 bases:

>100_bases
ACCATGGCGGATCGCGCCCTTAATCTGGATGATTTTCTGTCCCGCTTTCAGCTTCTGCGCCCGCAGCCTTCGCGCCATGC
GCTCAATCAGCGGCAGGCGG

Product: para-aminobenzoate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MGRNYFTPSPTTPEGRQRSGSRKMLSPAIITLPWRPDAAEHYFAPLSALPWAMLLHSGFADHPHNRFDILVAAPRATLLT
RGEQTWVDDGETVVVSAEDPLQLLQQQLDRQPFTPQPHDDLPFLGGALGLFGYDLGRRFERLPSHAQADIALADMAVGIY
DWALIVDHQRQQISLLSYDDPQQRLQWLEAQTPTPGETFALSSAWQSNMSRQQYGEKFRQVQAYLHSGDCYQVNLAQRFQ
ASYVGDEWQAFRQLNAVNRAPFSAFIRLDEGAILSLSPERFIQLRQGEIQTRPIKGTLPRLDSPLADAQQAEKLANSPKD
RAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVSTITARLPMTLHASDLLRAAFPGGSITGAPKVRAMEII
DELEPQRRNAWCGSIGYLSYCGNMDTSITIRTLTAWQGQLYCSAGGGIVADSEEAAEYQETFDKVNRILQQLEN

Sequences:

>Translated_474_residues
MGRNYFTPSPTTPEGRQRSGSRKMLSPAIITLPWRPDAAEHYFAPLSALPWAMLLHSGFADHPHNRFDILVAAPRATLLT
RGEQTWVDDGETVVVSAEDPLQLLQQQLDRQPFTPQPHDDLPFLGGALGLFGYDLGRRFERLPSHAQADIALADMAVGIY
DWALIVDHQRQQISLLSYDDPQQRLQWLEAQTPTPGETFALSSAWQSNMSRQQYGEKFRQVQAYLHSGDCYQVNLAQRFQ
ASYVGDEWQAFRQLNAVNRAPFSAFIRLDEGAILSLSPERFIQLRQGEIQTRPIKGTLPRLDSPLADAQQAEKLANSPKD
RAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVSTITARLPMTLHASDLLRAAFPGGSITGAPKVRAMEII
DELEPQRRNAWCGSIGYLSYCGNMDTSITIRTLTAWQGQLYCSAGGGIVADSEEAAEYQETFDKVNRILQQLEN
>Mature_473_residues
GRNYFTPSPTTPEGRQRSGSRKMLSPAIITLPWRPDAAEHYFAPLSALPWAMLLHSGFADHPHNRFDILVAAPRATLLTR
GEQTWVDDGETVVVSAEDPLQLLQQQLDRQPFTPQPHDDLPFLGGALGLFGYDLGRRFERLPSHAQADIALADMAVGIYD
WALIVDHQRQQISLLSYDDPQQRLQWLEAQTPTPGETFALSSAWQSNMSRQQYGEKFRQVQAYLHSGDCYQVNLAQRFQA
SYVGDEWQAFRQLNAVNRAPFSAFIRLDEGAILSLSPERFIQLRQGEIQTRPIKGTLPRLDSPLADAQQAEKLANSPKDR
AENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVSTITARLPMTLHASDLLRAAFPGGSITGAPKVRAMEIID
ELEPQRRNAWCGSIGYLSYCGNMDTSITIRTLTAWQGQLYCSAGGGIVADSEEAAEYQETFDKVNRILQQLEN

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=452, Percent_Identity=76.5486725663717, Blast_Score=712, Evalue=0.0,
Organism=Escherichia coli, GI1787518, Length=408, Percent_Identity=31.1274509803922, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1786809, Length=206, Percent_Identity=27.1844660194175, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=444, Percent_Identity=31.0810810810811, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324361, Length=398, Percent_Identity=28.894472361809, Blast_Score=154, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 52975; Mature: 52844

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRNYFTPSPTTPEGRQRSGSRKMLSPAIITLPWRPDAAEHYFAPLSALPWAMLLHSGFA
CCCCCCCCCCCCCCCHHCCCCCCCCCCEEEEECCCCCCHHHHHCCHHHHHHHHHHHCCCC
DHPHNRFDILVAAPRATLLTRGEQTWVDDGETVVVSAEDPLQLLQQQLDRQPFTPQPHDD
CCCCCCEEEEEECCCHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCC
LPFLGGALGLFGYDLGRRFERLPSHAQADIALADMAVGIYDWALIVDHQRQQISLLSYDD
CCHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHEEECCCCCEEEEECCCC
PQQRLQWLEAQTPTPGETFALSSAWQSNMSRQQYGEKFRQVQAYLHSGDCYQVNLAQRFQ
HHHHHHHHHCCCCCCCCCEEEHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHH
ASYVGDEWQAFRQLNAVNRAPFSAFIRLDEGAILSLSPERFIQLRQGEIQTRPIKGTLPR
HHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECHHHHHHHHCCCCEECCCCCCCCC
LDSPLADAQQAEKLANSPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHH
CCCCHHHHHHHHHHHCCCHHHHCCEEEEEEHHCCCCCEECCCCCCCCEEEEECCCHHHHH
LVSTITARLPMTLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSY
HHHHHHHHCCCEECHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHCCCCCCCHHHHH
CGNMDTSITIRTLTAWQGQLYCSAGGGIVADSEEAAEYQETFDKVNRILQQLEN
CCCCCCEEEEEEEEECCCEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GRNYFTPSPTTPEGRQRSGSRKMLSPAIITLPWRPDAAEHYFAPLSALPWAMLLHSGFA
CCCCCCCCCCCCCCHHCCCCCCCCCCEEEEECCCCCCHHHHHCCHHHHHHHHHHHCCCC
DHPHNRFDILVAAPRATLLTRGEQTWVDDGETVVVSAEDPLQLLQQQLDRQPFTPQPHDD
CCCCCCEEEEEECCCHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCC
LPFLGGALGLFGYDLGRRFERLPSHAQADIALADMAVGIYDWALIVDHQRQQISLLSYDD
CCHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHEEECCCCCEEEEECCCC
PQQRLQWLEAQTPTPGETFALSSAWQSNMSRQQYGEKFRQVQAYLHSGDCYQVNLAQRFQ
HHHHHHHHHCCCCCCCCCEEEHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHH
ASYVGDEWQAFRQLNAVNRAPFSAFIRLDEGAILSLSPERFIQLRQGEIQTRPIKGTLPR
HHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECHHHHHHHHCCCCEECCCCCCCCC
LDSPLADAQQAEKLANSPKDRAENLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHH
CCCCHHHHHHHHHHHCCCHHHHCCEEEEEEHHCCCCCEECCCCCCCCEEEEECCCHHHHH
LVSTITARLPMTLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSY
HHHHHHHHCCCEECHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHCCCCCCCHHHHH
CGNMDTSITIRTLTAWQGQLYCSAGGGIVADSEEAAEYQETFDKVNRILQQLEN
CCCCCCEEEEEEEEECCCEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]