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The map label for this gene is sufC [H]

Identifier: 238895189

GI number: 238895189

Start: 3069995

End: 3070741

Strand: Reverse

Name: sufC [H]

Synonym: KP1_3235

Alternate gene names: 238895189

Gene position: 3070741-3069995 (Counterclockwise)

Preceding gene: 238895190

Following gene: 238895188

Centisome position: 58.51

GC content: 54.89

Gene sequence:

>747_bases
ATGTTAAGTATTCAAGATTTACACGTCGCCGTCGAAGATAAAGCGATCCTGCGCGGGCTGAACCTTGAGGTGCGCCCGGG
AGAGGTCCACGCCATTATGGGGCCGAACGGCTCAGGCAAAAGTACGCTTTCGGCCACCCTGGCCGGGCGTGAAGATTATG
AGGTGACTGGCGGTCGCGTTGAATTTAAGGGCAAAAACCTGCTCGAACTCGCTGCGGAAGATCGCGCCGGGGAAGGTATC
TTTATGGCCTTCCAGTATCCGGTAGAGATCCCCGGCGTCAGCAACCAGTTTTTCCTGCAGACTGCGCTGAATGCCGTGCG
CAACTATCGTGGCCAGGAGGCGCTGGATCGTTTCGATTTCCAGGACTTAATGGAAGAAAAGATCAAGCTGCTGCAGATGC
CGGAAGATCTCCTGACCCGCTCGGTGAACGTTGGCTTCTCCGGCGGTGAGAAAAAGCGCAACGATATTCTGCAAATGGCG
GTGCTTGAGCCAGAGCTGTGCATCCTCGATGAATCGGATTCGGGGTTGGATATCGATGCCCTGAAAATCGTCTCGCAGGG
AGTGAATGCCCTGCGCGACGGCAAACGCGCCTTTATCATTGTCACCCACTATCAGCGCATCCTTGACTATATCAAGCCGG
ACTATGTCCATGTGCTGTATCAGGGACGGATTGTGAAGTCGGGCGATTTCTCTCTGGTCAAACAGCTGGAGGAGCAGGGC
TATGGCTGGCTTACCGAACAGCAGTAA

Upstream 100 bases:

>100_bases
GACGTCTTCTCCGAGCTGCCGCTGGAGTTCGCTGTAGAGGCGCAAAAATTGCTGGCCATTAGCCTTGAACATAGCGTCGG
CTGATAATTAAGGAAAAAAG

Downstream 100 bases:

>100_bases
CGCGCTGCAGCAGTGGCACCATCTGTTTGAAGCGCAGGGCGGCCCGCGTACCCCGGAGGCCAGTCAGCATCTGCAGCAGC
TGCTGCGCCTTGGGCTGCCG

Product: cysteine desulfurase ATPase component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MLSIQDLHVAVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREDYEVTGGRVEFKGKNLLELAAEDRAGEGI
FMAFQYPVEIPGVSNQFFLQTALNAVRNYRGQEALDRFDFQDLMEEKIKLLQMPEDLLTRSVNVGFSGGEKKRNDILQMA
VLEPELCILDESDSGLDIDALKIVSQGVNALRDGKRAFIIVTHYQRILDYIKPDYVHVLYQGRIVKSGDFSLVKQLEEQG
YGWLTEQQ

Sequences:

>Translated_248_residues
MLSIQDLHVAVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREDYEVTGGRVEFKGKNLLELAAEDRAGEGI
FMAFQYPVEIPGVSNQFFLQTALNAVRNYRGQEALDRFDFQDLMEEKIKLLQMPEDLLTRSVNVGFSGGEKKRNDILQMA
VLEPELCILDESDSGLDIDALKIVSQGVNALRDGKRAFIIVTHYQRILDYIKPDYVHVLYQGRIVKSGDFSLVKQLEEQG
YGWLTEQQ
>Mature_248_residues
MLSIQDLHVAVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREDYEVTGGRVEFKGKNLLELAAEDRAGEGI
FMAFQYPVEIPGVSNQFFLQTALNAVRNYRGQEALDRFDFQDLMEEKIKLLQMPEDLLTRSVNVGFSGGEKKRNDILQMA
VLEPELCILDESDSGLDIDALKIVSQGVNALRDGKRAFIIVTHYQRILDYIKPDYVHVLYQGRIVKSGDFSLVKQLEEQG
YGWLTEQQ

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9961252, Length=241, Percent_Identity=26.5560165975104, Blast_Score=64, Evalue=9e-11,
Organism=Homo sapiens, GI4505771, Length=241, Percent_Identity=26.5560165975104, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787972, Length=248, Percent_Identity=91.9354838709677, Blast_Score=473, Evalue=1e-135,
Organism=Escherichia coli, GI1789864, Length=242, Percent_Identity=26.4462809917355, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788761, Length=210, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI48994883, Length=249, Percent_Identity=28.9156626506024, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787759, Length=244, Percent_Identity=27.0491803278689, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786654, Length=233, Percent_Identity=25.7510729613734, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786319, Length=188, Percent_Identity=29.2553191489362, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=236, Percent_Identity=28.3898305084746, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71996809, Length=221, Percent_Identity=26.2443438914027, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193209708, Length=235, Percent_Identity=28.5106382978723, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193211017, Length=221, Percent_Identity=26.2443438914027, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI193211015, Length=221, Percent_Identity=26.2443438914027, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71992290, Length=250, Percent_Identity=28.8, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193202349, Length=233, Percent_Identity=29.6137339055794, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=222, Percent_Identity=26.5765765765766, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25146777, Length=221, Percent_Identity=28.5067873303167, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281363262, Length=223, Percent_Identity=28.6995515695067, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24653245, Length=223, Percent_Identity=28.6995515695067, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI85816269, Length=223, Percent_Identity=26.0089686098655, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24580553, Length=223, Percent_Identity=26.0089686098655, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI85724864, Length=223, Percent_Identity=26.0089686098655, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24580555, Length=223, Percent_Identity=26.0089686098655, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI85726357, Length=239, Percent_Identity=27.6150627615063, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27748; Mature: 27748

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIQDLHVAVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREDYEVTGGRV
CCCCCCEEEEECCHHHHHCCCEEECCCCEEEEECCCCCCCCEEEEEECCCCCCEECCCEE
EFKGKNLLELAAEDRAGEGIFMAFQYPVEIPGVSNQFFLQTALNAVRNYRGQEALDRFDF
EECCCCEEEHHHCCCCCCEEEEEEECCEECCCCCCHHHHHHHHHHHHHCCCHHHHHHCCH
QDLMEEKIKLLQMPEDLLTRSVNVGFSGGEKKRNDILQMAVLEPELCILDESDSGLDIDA
HHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHEECCCCEEEEECCCCCCCHHH
LKIVSQGVNALRDGKRAFIIVTHYQRILDYIKPDYVHVLYQGRIVKSGDFSLVKQLEEQG
HHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCEEEEEEECEEEECCCHHHHHHHHHCC
YGWLTEQQ
CCCCCCCC
>Mature Secondary Structure
MLSIQDLHVAVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREDYEVTGGRV
CCCCCCEEEEECCHHHHHCCCEEECCCCEEEEECCCCCCCCEEEEEECCCCCCEECCCEE
EFKGKNLLELAAEDRAGEGIFMAFQYPVEIPGVSNQFFLQTALNAVRNYRGQEALDRFDF
EECCCCEEEHHHCCCCCCEEEEEEECCEECCCCCCHHHHHHHHHHHHHCCCHHHHHHCCH
QDLMEEKIKLLQMPEDLLTRSVNVGFSGGEKKRNDILQMAVLEPELCILDESDSGLDIDA
HHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHEECCCCEEEEECCCCCCCHHH
LKIVSQGVNALRDGKRAFIIVTHYQRILDYIKPDYVHVLYQGRIVKSGDFSLVKQLEEQG
HHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCEEEEEEECEEEECCCHHHHHHHHHCC
YGWLTEQQ
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]