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The map label for this gene is mhpT [H]

Identifier: 238895165

GI number: 238895165

Start: 3046186

End: 3047382

Strand: Reverse

Name: mhpT [H]

Synonym: KP1_3211

Alternate gene names: 238895165

Gene position: 3047382-3046186 (Counterclockwise)

Preceding gene: 238895166

Following gene: 238895164

Centisome position: 58.06

GC content: 68.0

Gene sequence:

>1197_bases
ATGACCAAGATAACGACTGCAACCCCCTCGCGCCTGGTGGTCACCATCGGGCTCTGTTTTATGGTGGCCCTGATGGAAGG
GCTGGATCTGCAGGCGGCGGGGATCGCCGCCGTCGGCATGGCGCAGGCCTTTGCGCTGGATAAAATGCAGATGGGCTGGA
TCTTCAGCGCCGGGATCCTCGGCCTGCTGCCCGGCGCGCTGGTGGGCGGCATGCTGGCGGACCGCCACGGGCGTAAGCGC
ATTCTGTTGGGGTCGGTGCTGCTGTTTGGCCTGTTCTCGCTGGCCACCGCGCTGGCATGGAGCTTCCCGACGCTGCTGCT
GGCGCGCCTGCTCACCGGCGTCGGGCTCGGGGCGGCATTGCCGAACCTGATTGCCTTAACCTCGGAAGCCGCTGGCTCAC
GTTTCCGCGGCCGGGCGGTAAGCCTGATGTACTGCGGCGTACCCATTGGCGCCGCGCTGGCGGCAGCGCTGGGCTTTTCC
GGTCTCGCCGCGGCCTGGCAGACTATTTTCTGGATTGGCGGCGTGGTCCCGCTGCTGCTGATCCCGTTGCTGATGCGCTG
GCTGCCGGAGTCGCAGGCGTTTCAGCGCGCGGAGGTCAGCGTGCCGCTGCGCACCCTGTTTGCCCCGGGCCAGGCCGCCG
CTACGCTGCTGCTGTGGCTGGGTTATTTTTTCACCCTGCTGGTGGTCTATATGCTGATCAACTGGCTGCCGATGCTGCTG
GTGGGCCAGGGATTCCGCGCCAGCCAGGCGGCGGGGGTGATGTTCTCTCTGCAGATCGGCGCCGCCTGCGGCACGCTGCT
GCTGGGGGCGCTAATGGATAAGCTCACCCCGCTGCGGATGTCGCTCCTGATCTACAGCGGCATTCTGGCGTCGCTGTTGG
CGCTGGGCAGCGCGTCGTCGCTGACTGGCATGCTGCTGGCGGGGTTTGTCGCCGGGCTGTTCGCCACCGGCGGACAAAGT
GTGCTTTACGCTCTGGCGCCGCTTTTTTATCCCGCGGCCATCCGCGCCACCGGGGTGGGCACCGCCGTGGCGGTGGGGCG
TCTTGGGGCGATGAGCGGCCCGCTGCTGGCCGGCAAGATGCTGGCCCTCGGCACCGGCACCGTCGGGGTGATGGCGGCCT
CGGCGCCGGGCATTGTGTTGGCCGGCGTGGCGGTGTTCTGGCTGATGCATCGCCAGCAGCGCGCGGCCATGGTCTGA

Upstream 100 bases:

>100_bases
GGATCTGCTTAACCGCAATAAATAACTAAGAACGTGCGGCTGACAAAGCATCAGCCGCCAGTCACCTGCTCCGTTTGTTC
GGCTATCGCCAAGGTACCCT

Downstream 100 bases:

>100_bases
TATGCATCCGGCGGTCTGGTAAAAAAATGCCGGGCCGCCGCCTTGCCTGTCCGCGTCCCCTGGCCTAAGGTAAGACATCA
TTCCCTGACGCTTATCGTCC

Product: putative 3-hydroxyphenylpropionic transporter MhpT

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MTKITTATPSRLVVTIGLCFMVALMEGLDLQAAGIAAVGMAQAFALDKMQMGWIFSAGILGLLPGALVGGMLADRHGRKR
ILLGSVLLFGLFSLATALAWSFPTLLLARLLTGVGLGAALPNLIALTSEAAGSRFRGRAVSLMYCGVPIGAALAAALGFS
GLAAAWQTIFWIGGVVPLLLIPLLMRWLPESQAFQRAEVSVPLRTLFAPGQAAATLLLWLGYFFTLLVVYMLINWLPMLL
VGQGFRASQAAGVMFSLQIGAACGTLLLGALMDKLTPLRMSLLIYSGILASLLALGSASSLTGMLLAGFVAGLFATGGQS
VLYALAPLFYPAAIRATGVGTAVAVGRLGAMSGPLLAGKMLALGTGTVGVMAASAPGIVLAGVAVFWLMHRQQRAAMV

Sequences:

>Translated_398_residues
MTKITTATPSRLVVTIGLCFMVALMEGLDLQAAGIAAVGMAQAFALDKMQMGWIFSAGILGLLPGALVGGMLADRHGRKR
ILLGSVLLFGLFSLATALAWSFPTLLLARLLTGVGLGAALPNLIALTSEAAGSRFRGRAVSLMYCGVPIGAALAAALGFS
GLAAAWQTIFWIGGVVPLLLIPLLMRWLPESQAFQRAEVSVPLRTLFAPGQAAATLLLWLGYFFTLLVVYMLINWLPMLL
VGQGFRASQAAGVMFSLQIGAACGTLLLGALMDKLTPLRMSLLIYSGILASLLALGSASSLTGMLLAGFVAGLFATGGQS
VLYALAPLFYPAAIRATGVGTAVAVGRLGAMSGPLLAGKMLALGTGTVGVMAASAPGIVLAGVAVFWLMHRQQRAAMV
>Mature_397_residues
TKITTATPSRLVVTIGLCFMVALMEGLDLQAAGIAAVGMAQAFALDKMQMGWIFSAGILGLLPGALVGGMLADRHGRKRI
LLGSVLLFGLFSLATALAWSFPTLLLARLLTGVGLGAALPNLIALTSEAAGSRFRGRAVSLMYCGVPIGAALAAALGFSG
LAAAWQTIFWIGGVVPLLLIPLLMRWLPESQAFQRAEVSVPLRTLFAPGQAAATLLLWLGYFFTLLVVYMLINWLPMLLV
GQGFRASQAAGVMFSLQIGAACGTLLLGALMDKLTPLRMSLLIYSGILASLLALGSASSLTGMLLAGFVAGLFATGGQSV
LYALAPLFYPAAIRATGVGTAVAVGRLGAMSGPLLAGKMLALGTGTVGVMAASAPGIVLAGVAVFWLMHRQQRAAMV

Specific function: Could be a transporter for 3-phenylpropionate (hydrocinnamic acid) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081723, Length=384, Percent_Identity=83.0729166666667, Blast_Score=576, Evalue=1e-166,
Organism=Escherichia coli, GI87082231, Length=186, Percent_Identity=25.2688172043011, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41023; Mature: 40892

Theoretical pI: Translated: 11.21; Mature: 11.21

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKITTATPSRLVVTIGLCFMVALMEGLDLQAAGIAAVGMAQAFALDKMQMGWIFSAGIL
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLPGALVGGMLADRHGRKRILLGSVLLFGLFSLATALAWSFPTLLLARLLTGVGLGAAL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
PNLIALTSEAAGSRFRGRAVSLMYCGVPIGAALAAALGFSGLAAAWQTIFWIGGVVPLLL
HHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
IPLLMRWLPESQAFQRAEVSVPLRTLFAPGQAAATLLLWLGYFFTLLVVYMLINWLPMLL
HHHHHHHCCCHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGQGFRASQAAGVMFSLQIGAACGTLLLGALMDKLTPLRMSLLIYSGILASLLALGSASS
HCCCCCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LTGMLLAGFVAGLFATGGQSVLYALAPLFYPAAIRATGVGTAVAVGRLGAMSGPLLAGKM
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHH
LALGTGTVGVMAASAPGIVLAGVAVFWLMHRQQRAAMV
HHCCCCCHHHEECCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKITTATPSRLVVTIGLCFMVALMEGLDLQAAGIAAVGMAQAFALDKMQMGWIFSAGIL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLPGALVGGMLADRHGRKRILLGSVLLFGLFSLATALAWSFPTLLLARLLTGVGLGAAL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
PNLIALTSEAAGSRFRGRAVSLMYCGVPIGAALAAALGFSGLAAAWQTIFWIGGVVPLLL
HHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
IPLLMRWLPESQAFQRAEVSVPLRTLFAPGQAAATLLLWLGYFFTLLVVYMLINWLPMLL
HHHHHHHCCCHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGQGFRASQAAGVMFSLQIGAACGTLLLGALMDKLTPLRMSLLIYSGILASLLALGSASS
HCCCCCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LTGMLLAGFVAGLFATGGQSVLYALAPLFYPAAIRATGVGTAVAVGRLGAMSGPLLAGKM
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHH
LALGTGTVGVMAASAPGIVLAGVAVFWLMHRQQRAAMV
HHCCCCCHHHEECCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]