Click here to switch to the map view.

The map label for this gene is ccmG [H]

Identifier: 238895111

GI number: 238895111

Start: 2989040

End: 2989594

Strand: Reverse

Name: ccmG [H]

Synonym: KP1_3150

Alternate gene names: 238895111

Gene position: 2989594-2989040 (Counterclockwise)

Preceding gene: 238895112

Following gene: 238895110

Centisome position: 56.96

GC content: 63.78

Gene sequence:

>555_bases
ATGAACCGGAAGCTACTGTTTATCCCGCTGGTGCTGTTTCTGGCGCTGGCCGCCGCGCTGTTCTGGCAACTGATGCGCAA
CGCCGAGGGCGATGACCCGACGACCCTCGAGTCGGCGCTGATTGGCAAACCGCTGCCGGAATTTCGCCTTGAAGCGCTGA
ATACCCCCGGTCAGACGCTGGACCGACGGACGCTGATTGACGGCAAGCCGCTGCTGCTCAACGTCTGGGCCACCTGGTGT
CCAACCTGTCGCGCCGAGCATCAGTTTCTCAACGGCCTGGCGCAGCAGGGCGTGCGGGTGGTGGGGATGAACTACAAAGA
CGATCGCCAGAAGGCGATGAGCTGGCTGCAGCGCCTGGGTAATCCCTACAGGCTGAGCCTCTACGACGGCAACGGCATGC
TTGGCCTGGATCTCGGGGTCTATGGCGCGCCGGAGACGTTTCTCATCGACGGTCAGGGCATTATCCGCTGGCGGCACGCC
GGCGACCTGAACGAACGGGTGTGGCGCGAGGAGCTCCAGCCGCTGTGGGATCAATACAACCGGAGGGCGGGCTGA

Upstream 100 bases:

>100_bases
TTCGCTGGATCTGGTACGGCGGGGTGCTGATGGCCCTCGGCGGTCTGTGCTGCATGCTCGATCCGCGCTACCGGATGCGT
AAGAAGCTGCAGGAGGCCTC

Downstream 100 bases:

>100_bases
TGAGACGTGTAATAGTCATCCTGCTGGCCCTGATGCTGACCGGCCAGACGTGGGCCGCCATCGATACCTGGCAGTTTAAG
GATGAGGCCCAGGAGCAGGC

Product: heme lyase/disulfide oxidoreductase

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CcmG [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MNRKLLFIPLVLFLALAAALFWQLMRNAEGDDPTTLESALIGKPLPEFRLEALNTPGQTLDRRTLIDGKPLLLNVWATWC
PTCRAEHQFLNGLAQQGVRVVGMNYKDDRQKAMSWLQRLGNPYRLSLYDGNGMLGLDLGVYGAPETFLIDGQGIIRWRHA
GDLNERVWREELQPLWDQYNRRAG

Sequences:

>Translated_184_residues
MNRKLLFIPLVLFLALAAALFWQLMRNAEGDDPTTLESALIGKPLPEFRLEALNTPGQTLDRRTLIDGKPLLLNVWATWC
PTCRAEHQFLNGLAQQGVRVVGMNYKDDRQKAMSWLQRLGNPYRLSLYDGNGMLGLDLGVYGAPETFLIDGQGIIRWRHA
GDLNERVWREELQPLWDQYNRRAG
>Mature_184_residues
MNRKLLFIPLVLFLALAAALFWQLMRNAEGDDPTTLESALIGKPLPEFRLEALNTPGQTLDRRTLIDGKPLLLNVWATWC
PTCRAEHQFLNGLAQQGVRVVGMNYKDDRQKAMSWLQRLGNPYRLSLYDGNGMLGLDLGVYGAPETFLIDGQGIIRWRHA
GDLNERVWREELQPLWDQYNRRAG

Specific function: Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=184, Percent_Identity=75, Blast_Score=300, Evalue=3e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 21035; Mature: 21035

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRKLLFIPLVLFLALAAALFWQLMRNAEGDDPTTLESALIGKPLPEFRLEALNTPGQTL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCHH
DRRTLIDGKPLLLNVWATWCPTCRAEHQFLNGLAQQGVRVVGMNYKDDRQKAMSWLQRLG
CCHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCC
NPYRLSLYDGNGMLGLDLGVYGAPETFLIDGQGIIRWRHAGDLNERVWREELQPLWDQYN
CCEEEEEECCCCEEEEECCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
RRAG
CCCC
>Mature Secondary Structure
MNRKLLFIPLVLFLALAAALFWQLMRNAEGDDPTTLESALIGKPLPEFRLEALNTPGQTL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCHH
DRRTLIDGKPLLLNVWATWCPTCRAEHQFLNGLAQQGVRVVGMNYKDDRQKAMSWLQRLG
CCHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCC
NPYRLSLYDGNGMLGLDLGVYGAPETFLIDGQGIIRWRHAGDLNERVWREELQPLWDQYN
CCEEEEEECCCCEEEEECCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
RRAG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]