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The map label for this gene is pcbC [H]

Identifier: 238895074

GI number: 238895074

Start: 2955417

End: 2956412

Strand: Reverse

Name: pcbC [H]

Synonym: KP1_3106

Alternate gene names: 238895074

Gene position: 2956412-2955417 (Counterclockwise)

Preceding gene: 238895075

Following gene: 238895072

Centisome position: 56.33

GC content: 59.14

Gene sequence:

>996_bases
ATGACGATGAACGCAACCACCCAGAATCAACGCTACGCCTTACAGGAACTGGAAAAAGAGGCGCTGATGGGCGCCGAGGG
CGAAGAGACCTTCGCCCGCGAAGTGCGCTGTATCGACCTGTCGAACTTTGCCGCAAGAAAAAATGACATTGCCGAACAAC
TGTGGGAGGCGGCGGTGGAGATTGGCTTCTTCCAGGTCAGCCATCACGGTATTCCGCTGGCGGAGATCCGCCAGGCGTTC
AGCATGACCGAGGCGTTTTTCGACCTGCCCGACGAGGTGAAGCGCCAGTATCCGCTGGCCGGTAACGCCGGCTGGGAAAG
CAAAGCGCAGGTTCGGCCGTCGACTCGCACCCCGGATCAAAAAGAGTCGTATCAGATAACCCGGCCTCTGATGGCCGGGC
GCTGGCCCAGCGATCGGGAGTTGCCAGCATTCCAGCAGACAATGCTCGGGTTTGAGTCGCAGTGCTGGCAGCTGGGGATG
AAGATCCTCTCCTGCTTTGCTTTAAAGCTCGGTTTTCCGGAATCGTTTTTTACCACCGCGCACGATCCGCAGCGTGACAC
CTATCAGAGCACCTTGCGCATGCTGCATTACTATGCAACCGAGCAGTCGCAGCAGGGGATGTGGCGGGCCGGCGCGCACA
CCGATTTTGACTGTCTGACGCTGCTGTTCCAGCGCCCCGGCCAGGGCGGCCTGCAGGTTTGTCCCGGTAAAGACCGTGAA
AGCCAGCAGTGGACCAGCATTGAGCCGCGCGAGGAGGTGATCACCTGTAATATCGGCGATATGCTGATGCGCTGGAGCGA
CGACCAGCTGCCGTCTAACTTCCACCGGGTGAGAAATCCGCTGCCCCATGAATATCAGGGGCCGCGCTACAGCCTGGCGT
TTTTTTGCCAGGCCAATAAAGATGTCGAGATCCTCGGGCCGCAGAGGAAGTACCCGCCCATCAGCGCCGAGGATTATCTG
CAGCAGCGGATCCAGGCCAATTTTGCCAAAGGGTAA

Upstream 100 bases:

>100_bases
ACGCCATTCCCGGTCTCGACCTTGACGCGATGCGCCACGACGCGCTGGCTGCCGTCCGTACCCTCCAACAGCGCGCCGCT
GTTTAACTGATAACAGGATA

Downstream 100 bases:

>100_bases
GATGCGCTCTTGAATGGTATACCTGCCGCCGGCTTTCGCTGGCCGGGCGGCAGGATCTCCGGCGCTGAGCTTTTCAGGTG
GTAGGGCTTGCCGATGCGGG

Product: putative dioxygenase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MTMNATTQNQRYALQELEKEALMGAEGEETFAREVRCIDLSNFAARKNDIAEQLWEAAVEIGFFQVSHHGIPLAEIRQAF
SMTEAFFDLPDEVKRQYPLAGNAGWESKAQVRPSTRTPDQKESYQITRPLMAGRWPSDRELPAFQQTMLGFESQCWQLGM
KILSCFALKLGFPESFFTTAHDPQRDTYQSTLRMLHYYATEQSQQGMWRAGAHTDFDCLTLLFQRPGQGGLQVCPGKDRE
SQQWTSIEPREEVITCNIGDMLMRWSDDQLPSNFHRVRNPLPHEYQGPRYSLAFFCQANKDVEILGPQRKYPPISAEDYL
QQRIQANFAKG

Sequences:

>Translated_331_residues
MTMNATTQNQRYALQELEKEALMGAEGEETFAREVRCIDLSNFAARKNDIAEQLWEAAVEIGFFQVSHHGIPLAEIRQAF
SMTEAFFDLPDEVKRQYPLAGNAGWESKAQVRPSTRTPDQKESYQITRPLMAGRWPSDRELPAFQQTMLGFESQCWQLGM
KILSCFALKLGFPESFFTTAHDPQRDTYQSTLRMLHYYATEQSQQGMWRAGAHTDFDCLTLLFQRPGQGGLQVCPGKDRE
SQQWTSIEPREEVITCNIGDMLMRWSDDQLPSNFHRVRNPLPHEYQGPRYSLAFFCQANKDVEILGPQRKYPPISAEDYL
QQRIQANFAKG
>Mature_330_residues
TMNATTQNQRYALQELEKEALMGAEGEETFAREVRCIDLSNFAARKNDIAEQLWEAAVEIGFFQVSHHGIPLAEIRQAFS
MTEAFFDLPDEVKRQYPLAGNAGWESKAQVRPSTRTPDQKESYQITRPLMAGRWPSDRELPAFQQTMLGFESQCWQLGMK
ILSCFALKLGFPESFFTTAHDPQRDTYQSTLRMLHYYATEQSQQGMWRAGAHTDFDCLTLLFQRPGQGGLQVCPGKDRES
QQWTSIEPREEVITCNIGDMLMRWSDDQLPSNFHRVRNPLPHEYQGPRYSLAFFCQANKDVEILGPQRKYPPISAEDYLQ
QRIQANFAKG

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI85816264, Length=282, Percent_Identity=31.9148936170213, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28572124, Length=282, Percent_Identity=28.3687943262411, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 38068; Mature: 37937

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMNATTQNQRYALQELEKEALMGAEGEETFAREVRCIDLSNFAARKNDIAEQLWEAAVE
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHH
IGFFQVSHHGIPLAEIRQAFSMTEAFFDLPDEVKRQYPLAGNAGWESKAQVRPSTRTPDQ
HHHEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
KESYQITRPLMAGRWPSDRELPAFQQTMLGFESQCWQLGMKILSCFALKLGFPESFFTTA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
HDPQRDTYQSTLRMLHYYATEQSQQGMWRAGAHTDFDCLTLLFQRPGQGGLQVCPGKDRE
CCCCHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCEECCCCCCC
SQQWTSIEPREEVITCNIGDMLMRWSDDQLPSNFHRVRNPLPHEYQGPRYSLAFFCQANK
CCCCCCCCCCHHEEEECHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEEEECCC
DVEILGPQRKYPPISAEDYLQQRIQANFAKG
CEEEECCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TMNATTQNQRYALQELEKEALMGAEGEETFAREVRCIDLSNFAARKNDIAEQLWEAAVE
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHH
IGFFQVSHHGIPLAEIRQAFSMTEAFFDLPDEVKRQYPLAGNAGWESKAQVRPSTRTPDQ
HHHEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
KESYQITRPLMAGRWPSDRELPAFQQTMLGFESQCWQLGMKILSCFALKLGFPESFFTTA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
HDPQRDTYQSTLRMLHYYATEQSQQGMWRAGAHTDFDCLTLLFQRPGQGGLQVCPGKDRE
CCCCHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCEECCCCCCC
SQQWTSIEPREEVITCNIGDMLMRWSDDQLPSNFHRVRNPLPHEYQGPRYSLAFFCQANK
CCCCCCCCCCHHEEEECHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEEEECCC
DVEILGPQRKYPPISAEDYLQQRIQANFAKG
CEEEECCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3045077 [H]