Click here to switch to the map view.

The map label for this gene is ansP [H]

Identifier: 238894944

GI number: 238894944

Start: 2832671

End: 2834125

Strand: Direct

Name: ansP [H]

Synonym: KP1_2969

Alternate gene names: 238894944

Gene position: 2832671-2834125 (Clockwise)

Preceding gene: 238894943

Following gene: 238894947

Centisome position: 53.97

GC content: 58.97

Gene sequence:

>1455_bases
ATGAATACGAAACACGAAAGTGCAGCGGAGCATCATGCTGCAAAACGCCACTGGCTTAACTCACATGAAGCGGGTTATCA
CAAAGCGATGGGCAACCGTCAGGTACAGATGATCGCCATCGGCGGCGCCATCGGTACCGGTTTGTTCCTCGGCGCCGGGG
CACGTTTACAAATGGCAGGGCCAGCGCTCGCCCTGGTCTATCTGGTCTGCGGCATCTTCTCCTTCTTTATTCTTCGCGCC
CTCGGCGAACTGGTCCTCCACCGCCCCTCGAGCGGCAGCTTCGTCTCTTATGCCAGGGAGTTCCTCGGTGAAAAAGCCGC
TTACGTGGCCGGCTGGATGTACTTCGTTAACTGGGCGATGACCGGGATTGTCGATATCACCGCCGTGGCGCTGTATATGC
ACTACTGGGGCGCGTTTGGCGATGTGCCGCAGTGGGTCTTCGCCCTCGGCGCGCTGGCTATCGTCGGCACCATGAATATG
ATCGGCGTGAAGTGGTTCGCCGAAATGGAGTTCTGGTTCGCGCTGGTTAAGGTGCTGGCGATCGTCGCCTTTCTCGTGGT
CGGCACCATTTTCCTCGGCTCCGGTAAGCCGCTGGACGGCAATGCCACCGGCTTCCATCTGATCACCGATAACGGCGGCT
TCTTCCCGCACGGCCTCCTGCCGGCGCTGGTGCTGGTGCAGGGGGTGGTCTTCGCCTTCGCCTCCATCGAGCTGGTGGGG
ACCGCGGCCGGAGAGTGTAAGGATCCGGAGACAATGGTGCCGAAGGCCATCAACAGCGTGATCTGGCGTATCGGTCTGTT
CTATGTCGGTTCGGTGGTGTTGCTGGTGCTGCTTCTGCCGTGGAACGCCTACCAGGCCGGACAGAGCCCGTTCGTTACCT
TCTTCTCAAAGCTGGGCGTGCCATATATCGGCAGCGTGATGAACATCGTGGTGTTAACCGCGGCCCTCTCCAGCCTTAAC
TCGGGTCTCTACAGTACCGGGCGTATTCTGCGCTCGATGTCGATGGGAGGCTCCGCGCCGAAGTTTATGTCGAAGATGAG
CCGTCACCACGTCCCTTACGCCGGGATCCTGGCGACGCTGGGGGTATATGTAGTTGGGGTTTTCCTCAACTATCTGGTGC
CATCTCAGGTATTTGAGATCGTACTCAACGTCGCCTCGCTGGGGATCATTGCCTCCTGGGGCTTTATCGTGGTGTGTCAG
ATGCGTCTGCGCAAAGCGATCAAGGAAGGGAAAGCGGCAAAGGTCAGCTTCAGAATGCCGGGGGCGCCGTTCACCTCCTG
GCTGACGCTGCTGTTCCTGTTCAGCGTGCTGGTGCTGATGGCCTTCGATTATCCGAACGGTACCTACACCATAGGATCAA
TTCCGCTGCTGGCGGTATTGCTGGTGGCTGGCTGGTTTGGTGTGCGTAAACGCGTGCATGAGATTCACAGCACGGCGCCG
ACGCTGAGGAAGTAA

Upstream 100 bases:

>100_bases
CTTATCTCCTACGTCAGAATGATGAGAAAGCCAGCATAATGTGCCAGCCGTCCTCCATTCCGGCTGCAAACATGGGCATT
GACAGGAAACTGATACATCA

Downstream 100 bases:

>100_bases
CTGGCAGGACTCCCGGTTTGTCCATCGCGGGCAAACCGGGAGGTCAGAACTTAATTATCTTCAACCAGCTGCGACACATC
GCTGCTGTTAATTTCCCGCT

Product: L-asparagine permease

Products: Proton [Cytoplasm]; L-asparagine [Cytoplasm] [C]

Alternate protein names: L-asparagine transport protein [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MNTKHESAAEHHAAKRHWLNSHEAGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAGPALALVYLVCGIFSFFILRA
LGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFVNWAMTGIVDITAVALYMHYWGAFGDVPQWVFALGALAIVGTMNM
IGVKWFAEMEFWFALVKVLAIVAFLVVGTIFLGSGKPLDGNATGFHLITDNGGFFPHGLLPALVLVQGVVFAFASIELVG
TAAGECKDPETMVPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGVPYIGSVMNIVVLTAALSSLN
SGLYSTGRILRSMSMGGSAPKFMSKMSRHHVPYAGILATLGVYVVGVFLNYLVPSQVFEIVLNVASLGIIASWGFIVVCQ
MRLRKAIKEGKAAKVSFRMPGAPFTSWLTLLFLFSVLVLMAFDYPNGTYTIGSIPLLAVLLVAGWFGVRKRVHEIHSTAP
TLRK

Sequences:

>Translated_484_residues
MNTKHESAAEHHAAKRHWLNSHEAGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAGPALALVYLVCGIFSFFILRA
LGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFVNWAMTGIVDITAVALYMHYWGAFGDVPQWVFALGALAIVGTMNM
IGVKWFAEMEFWFALVKVLAIVAFLVVGTIFLGSGKPLDGNATGFHLITDNGGFFPHGLLPALVLVQGVVFAFASIELVG
TAAGECKDPETMVPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGVPYIGSVMNIVVLTAALSSLN
SGLYSTGRILRSMSMGGSAPKFMSKMSRHHVPYAGILATLGVYVVGVFLNYLVPSQVFEIVLNVASLGIIASWGFIVVCQ
MRLRKAIKEGKAAKVSFRMPGAPFTSWLTLLFLFSVLVLMAFDYPNGTYTIGSIPLLAVLLVAGWFGVRKRVHEIHSTAP
TLRK
>Mature_484_residues
MNTKHESAAEHHAAKRHWLNSHEAGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAGPALALVYLVCGIFSFFILRA
LGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFVNWAMTGIVDITAVALYMHYWGAFGDVPQWVFALGALAIVGTMNM
IGVKWFAEMEFWFALVKVLAIVAFLVVGTIFLGSGKPLDGNATGFHLITDNGGFFPHGLLPALVLVQGVVFAFASIELVG
TAAGECKDPETMVPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGVPYIGSVMNIVVLTAALSSLN
SGLYSTGRILRSMSMGGSAPKFMSKMSRHHVPYAGILATLGVYVVGVFLNYLVPSQVFEIVLNVASLGIIASWGFIVVCQ
MRLRKAIKEGKAAKVSFRMPGAPFTSWLTLLFLFSVLVLMAFDYPNGTYTIGSIPLLAVLLVAGWFGVRKRVHEIHSTAP
TLRK

Specific function: Unknown

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=419, Percent_Identity=22.1957040572792, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI258645169, Length=423, Percent_Identity=20.8037825059102, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87081915, Length=483, Percent_Identity=88.6128364389234, Blast_Score=860, Evalue=0.0,
Organism=Escherichia coli, GI1786789, Length=458, Percent_Identity=37.5545851528384, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI1786302, Length=462, Percent_Identity=36.7965367965368, Blast_Score=309, Evalue=2e-85,
Organism=Escherichia coli, GI1790653, Length=460, Percent_Identity=37.3913043478261, Blast_Score=302, Evalue=3e-83,
Organism=Escherichia coli, GI48994972, Length=466, Percent_Identity=36.480686695279, Blast_Score=298, Evalue=7e-82,
Organism=Escherichia coli, GI1786602, Length=448, Percent_Identity=37.2767857142857, Blast_Score=298, Evalue=7e-82,
Organism=Escherichia coli, GI1789017, Length=443, Percent_Identity=34.5372460496614, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI87081708, Length=431, Percent_Identity=34.5707656612529, Blast_Score=253, Evalue=3e-68,
Organism=Escherichia coli, GI1788480, Length=397, Percent_Identity=34.5088161209068, Blast_Score=229, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17532491, Length=437, Percent_Identity=21.7391304347826, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531343, Length=445, Percent_Identity=22.0224719101124, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324061, Length=461, Percent_Identity=28.8503253796095, Blast_Score=201, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6320772, Length=407, Percent_Identity=31.2039312039312, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6322892, Length=444, Percent_Identity=33.3333333333333, Blast_Score=193, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6324990, Length=488, Percent_Identity=29.0983606557377, Blast_Score=176, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6324924, Length=444, Percent_Identity=29.7297297297297, Blast_Score=172, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6321629, Length=455, Percent_Identity=27.4725274725275, Blast_Score=159, Evalue=9e-40,
Organism=Saccharomyces cerevisiae, GI6324059, Length=462, Percent_Identity=29.2207792207792, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6321053, Length=421, Percent_Identity=27.5534441805226, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6324553, Length=397, Percent_Identity=29.2191435768262, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319824, Length=426, Percent_Identity=28.8732394366197, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6322967, Length=409, Percent_Identity=28.361858190709, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6320717, Length=406, Percent_Identity=27.8325123152709, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6319543, Length=438, Percent_Identity=27.3972602739726, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6324981, Length=419, Percent_Identity=27.6849642004773, Blast_Score=141, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6320251, Length=456, Percent_Identity=25.8771929824561, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319608, Length=453, Percent_Identity=26.0485651214128, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6319542, Length=410, Percent_Identity=25.3658536585366, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24666159, Length=428, Percent_Identity=22.4299065420561, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI221512776, Length=428, Percent_Identity=22.4299065420561, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24668806, Length=416, Percent_Identity=22.3557692307692, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI21356285, Length=416, Percent_Identity=22.3557692307692, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24668802, Length=416, Percent_Identity=22.3557692307692, Blast_Score=79, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52402; Mature: 52402

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKHESAAEHHAAKRHWLNSHEAGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAG
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEEECCHHHHHHHHCCCCCEEECC
PALALVYLVCGIFSFFILRALGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFVNWAM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
TGIVDITAVALYMHYWGAFGDVPQWVFALGALAIVGTMNMIGVKWFAEMEFWFALVKVLA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVAFLVVGTIFLGSGKPLDGNATGFHLITDNGGFFPHGLLPALVLVQGVVFAFASIELVG
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
TAAGECKDPETMVPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCC
PYIGSVMNIVVLTAALSSLNSGLYSTGRILRSMSMGGSAPKFMSKMSRHHVPYAGILATL
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHH
GVYVVGVFLNYLVPSQVFEIVLNVASLGIIASWGFIVVCQMRLRKAIKEGKAAKVSFRMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
GAPFTSWLTLLFLFSVLVLMAFDYPNGTYTIGSIPLLAVLLVAGWFGVRKRVHEIHSTAP
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TLRK
CCCC
>Mature Secondary Structure
MNTKHESAAEHHAAKRHWLNSHEAGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAG
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEEECCHHHHHHHHCCCCCEEECC
PALALVYLVCGIFSFFILRALGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFVNWAM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
TGIVDITAVALYMHYWGAFGDVPQWVFALGALAIVGTMNMIGVKWFAEMEFWFALVKVLA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVAFLVVGTIFLGSGKPLDGNATGFHLITDNGGFFPHGLLPALVLVQGVVFAFASIELVG
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
TAAGECKDPETMVPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCC
PYIGSVMNIVVLTAALSSLNSGLYSTGRILRSMSMGGSAPKFMSKMSRHHVPYAGILATL
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHH
GVYVVGVFLNYLVPSQVFEIVLNVASLGIIASWGFIVVCQMRLRKAIKEGKAAKVSFRMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
GAPFTSWLTLLFLFSVLVLMAFDYPNGTYTIGSIPLLAVLLVAGWFGVRKRVHEIHSTAP
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TLRK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-asparagine [Periplasm]; Proton [Periplasm] [C]

Specific reaction: L-asparagine [Periplasm] + Proton [Periplasm] = Proton [Cytoplasm] + L-asparagine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]