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The map label for this gene is mgtC [H]

Identifier: 238894857

GI number: 238894857

Start: 2743335

End: 2744030

Strand: Reverse

Name: mgtC [H]

Synonym: KP1_2873

Alternate gene names: 238894857

Gene position: 2744030-2743335 (Counterclockwise)

Preceding gene: 238894859

Following gene: 238894856

Centisome position: 52.28

GC content: 60.63

Gene sequence:

>696_bases
CTGGAGGAAGGCGCGATGGTATTTCCTTATATGACACATTTACTCGCGGCAATGTTGTTGGGGGCGCTGATCGGCGCGGA
ACGACAGTGGCGACAACGTATGGCCGGTTTACGCACCAATGCCCTGGTGGCCACCGGCGCGGCGGTGTTTATTCTCAGCG
CGATGTCGGCCTCGCCGGACAGCCCGGGGCGTATTGCAGCGCAGATCGTCTCCGGTATCGGCTTCCTTGGGGCAGGGGTG
ATTATGCGCGATGGTATGAACGTCCGCGGCCTCAATACCGCCGCCACGCTGTGGTGTTCGGCCGGGATCGGCGTACTCTG
CGGCCTGGGACAGTTCTGGAACGCGACGGCGGCTACGCTGATTATTCTGTGCGCCAATATCCTGCTGCGCGAGGCGGCGC
AGCGCATTCATGCCTTGCCGGGGGCCGGTGACGAAGAGAAACGCTATGTCTTACGCGTCACCTGTCTGCGCGAACATGAA
AATGCCGTACGTCAGCTGTTGCTGAATATTGCGCAGCAGCAGCGGTTTACCCTGCAGGGATTGCAGTCGGCGGCGGCGGA
CACAGCGGACCATCTGGAGATTTGCGCGCAGCTGATTAGCCATAAGCAGCACCAAAAAACGCTGGCGCAAATTATGGCGC
AGATGGGCGTTCAGCAGAACGTCACATCGGTGCACTGGCGTGTCGGAGAGGCGTAG

Upstream 100 bases:

>100_bases
TGTTTATGTTTTCCAGACCCTTATTTCCTCCACCATCATCCACCGGCTAATCGCCCGGCGCGGCTGAGCGCTACATCTGT
AATTTTTGGCTTTCTGTTTT

Downstream 100 bases:

>100_bases
GGGCTGGCGGCGGAGCAGCGGAAACGGCCGCTCGTCGCGCGATTCGCCATCCCGCGGGAAAGCGGCTAGAATGGCCTCCT
CGCAGGAGGTTATAAGAATG

Product: putative Mg(2+) transport ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MEEGAMVFPYMTHLLAAMLLGALIGAERQWRQRMAGLRTNALVATGAAVFILSAMSASPDSPGRIAAQIVSGIGFLGAGV
IMRDGMNVRGLNTAATLWCSAGIGVLCGLGQFWNATAATLIILCANILLREAAQRIHALPGAGDEEKRYVLRVTCLREHE
NAVRQLLLNIAQQQRFTLQGLQSAAADTADHLEICAQLISHKQHQKTLAQIMAQMGVQQNVTSVHWRVGEA

Sequences:

>Translated_231_residues
MEEGAMVFPYMTHLLAAMLLGALIGAERQWRQRMAGLRTNALVATGAAVFILSAMSASPDSPGRIAAQIVSGIGFLGAGV
IMRDGMNVRGLNTAATLWCSAGIGVLCGLGQFWNATAATLIILCANILLREAAQRIHALPGAGDEEKRYVLRVTCLREHE
NAVRQLLLNIAQQQRFTLQGLQSAAADTADHLEICAQLISHKQHQKTLAQIMAQMGVQQNVTSVHWRVGEA
>Mature_231_residues
MEEGAMVFPYMTHLLAAMLLGALIGAERQWRQRMAGLRTNALVATGAAVFILSAMSASPDSPGRIAAQIVSGIGFLGAGV
IMRDGMNVRGLNTAATLWCSAGIGVLCGLGQFWNATAATLIILCANILLREAAQRIHALPGAGDEEKRYVLRVTCLREHE
NAVRQLLLNIAQQQRFTLQGLQSAAADTADHLEICAQLISHKQHQKTLAQIMAQMGVQQNVTSVHWRVGEA

Specific function: Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase [H]

COG id: COG1285

COG function: function code S; Uncharacterized membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MgtC/SapB family [H]

Homologues:

Organism=Escherichia coli, GI1789924, Length=108, Percent_Identity=43.5185185185185, Blast_Score=84, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003416 [H]

Pfam domain/function: PF02308 MgtC [H]

EC number: NA

Molecular weight: Translated: 24822; Mature: 24822

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEGAMVFPYMTHLLAAMLLGALIGAERQWRQRMAGLRTNALVATGAAVFILSAMSASPD
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
SPGRIAAQIVSGIGFLGAGVIMRDGMNVRGLNTAATLWCSAGIGVLCGLGQFWNATAATL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHCCHHHHHHHHHHH
IILCANILLREAAQRIHALPGAGDEEKRYVLRVTCLREHENAVRQLLLNIAQQQRFTLQG
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQSAAADTADHLEICAQLISHKQHQKTLAQIMAQMGVQQNVTSVHWRVGEA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEECCCC
>Mature Secondary Structure
MEEGAMVFPYMTHLLAAMLLGALIGAERQWRQRMAGLRTNALVATGAAVFILSAMSASPD
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
SPGRIAAQIVSGIGFLGAGVIMRDGMNVRGLNTAATLWCSAGIGVLCGLGQFWNATAATL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHCCHHHHHHHHHHH
IILCANILLREAAQRIHALPGAGDEEKRYVLRVTCLREHENAVRQLLLNIAQQQRFTLQG
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQSAAADTADHLEICAQLISHKQHQKTLAQIMAQMGVQQNVTSVHWRVGEA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA