Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 238894841

GI number: 238894841

Start: 2726072

End: 2726812

Strand: Reverse

Name: ompR [H]

Synonym: KP1_2858

Alternate gene names: 238894841

Gene position: 2726812-2726072 (Counterclockwise)

Preceding gene: 238894842

Following gene: 238894840

Centisome position: 51.95

GC content: 61.54

Gene sequence:

>741_bases
TTGGAGCGTATTGACCACATCCTGGTCGTCGACGACGACCGCGACATCCGGGAACTGATTGTCGACTATCTGGAAAAATC
GGGATATCGCGCCAGCGGCGCGGCGAACGGCAAAGCCATGTGGTCGGTACTCAAAAACCATCAAATTGACCTGATTGTGC
TGGATATTATGATGCCGGGTGAGGATGGCTTAACGCTCTGTCGCCAGCTGCGCGCCAACCCGCAGCAGGATATCCCGGTG
CTGATGCTCACCGCCCGCACCGATGACAGCGACCGGATCCTCGGCCTGGAAATGGGGGCTGACGATTATCTGATTAAGCC
CTTTGTGGCCCGCGAACTGCTGGCGCGCATCAAAGCCATTTTACGCCGCACCCGGGCGCTGCCGCCCAACCTGCAGATCA
CCGAGACGGGCAGGCTGATCGCCTTTGGCGACTGGCTGCTCGACACTGCCGCTCGCCATTTGCTGGACGACAGCGGCGCC
ATCGTCGCCCTCAGCGGGGCGGAGTATCGGCTGCTGCGGGTGTTTCTCGACCATCCCCAGCGGGTGCTGAACCGCGATCA
GCTGCTCAATCTGACCCAGGGACGCGACGCGGAACTGTTTGAGCGGTCGATTGACCTGCTGGTGAGCCGACTGCGCCAGC
GGCTACGGGAGGATGCCCGCGAGCCGGCCTACATTAAAACGGTGCGCAGCGAAGGCTATGTGCTGTCGGTGCCGGTCTCC
ATTCGCGAGAGGCATGAATGA

Upstream 100 bases:

>100_bases
CCGATCGTTTGTAACCGGCGCCTTGCCGGCGGCGCGACGTTGCGCTTCCGGCAACACGGCTTATGCTTGTGAAGAGTTTA
TTTTGCCGCAGGAGCAGCCT

Downstream 100 bases:

>100_bases
GGTTCTGGCCCGCCTCGCTGCAGTCGAGGCTGATGGCGCTGCTGTTTCTGGCGCTGCTGCTGGCGAATACCTTAACCCTG
TCGCTGCTGTTTTATGAGCG

Product: putative two-component response transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MERIDHILVVDDDRDIRELIVDYLEKSGYRASGAANGKAMWSVLKNHQIDLIVLDIMMPGEDGLTLCRQLRANPQQDIPV
LMLTARTDDSDRILGLEMGADDYLIKPFVARELLARIKAILRRTRALPPNLQITETGRLIAFGDWLLDTAARHLLDDSGA
IVALSGAEYRLLRVFLDHPQRVLNRDQLLNLTQGRDAELFERSIDLLVSRLRQRLREDAREPAYIKTVRSEGYVLSVPVS
IRERHE

Sequences:

>Translated_246_residues
MERIDHILVVDDDRDIRELIVDYLEKSGYRASGAANGKAMWSVLKNHQIDLIVLDIMMPGEDGLTLCRQLRANPQQDIPV
LMLTARTDDSDRILGLEMGADDYLIKPFVARELLARIKAILRRTRALPPNLQITETGRLIAFGDWLLDTAARHLLDDSGA
IVALSGAEYRLLRVFLDHPQRVLNRDQLLNLTQGRDAELFERSIDLLVSRLRQRLREDAREPAYIKTVRSEGYVLSVPVS
IRERHE
>Mature_246_residues
MERIDHILVVDDDRDIRELIVDYLEKSGYRASGAANGKAMWSVLKNHQIDLIVLDIMMPGEDGLTLCRQLRANPQQDIPV
LMLTARTDDSDRILGLEMGADDYLIKPFVARELLARIKAILRRTRALPPNLQITETGRLIAFGDWLLDTAARHLLDDSGA
IVALSGAEYRLLRVFLDHPQRVLNRDQLLNLTQGRDAELFERSIDLLVSRLRQRLREDAREPAYIKTVRSEGYVLSVPVS
IRERHE

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=43.4042553191489, Blast_Score=190, Evalue=6e-50,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=34.2105263157895, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=36.6379310344828, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1788394, Length=232, Percent_Identity=36.2068965517241, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1787229, Length=239, Percent_Identity=35.5648535564854, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=36.2068965517241, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=37.9310344827586, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790860, Length=236, Percent_Identity=32.6271186440678, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=34.7826086956522, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787375, Length=234, Percent_Identity=32.0512820512821, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=32.1739130434783, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=31.140350877193, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=31.8777292576419, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=30.5555555555556, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790299, Length=131, Percent_Identity=32.0610687022901, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=164, Percent_Identity=32.9268292682927, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28099; Mature: 28099

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIDHILVVDDDRDIRELIVDYLEKSGYRASGAANGKAMWSVLKNHQIDLIVLDIMMPG
CCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEEECC
EDGLTLCRQLRANPQQDIPVLMLTARTDDSDRILGLEMGADDYLIKPFVARELLARIKAI
CCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
LRRTRALPPNLQITETGRLIAFGDWLLDTAARHLLDDSGAIVALSGAEYRLLRVFLDHPQ
HHHHHCCCCCCEEECCCCEEEEHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCHH
RVLNRDQLLNLTQGRDAELFERSIDLLVSRLRQRLREDAREPAYIKTVRSEGYVLSVPVS
HHHCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECHH
IRERHE
HHCCCC
>Mature Secondary Structure
MERIDHILVVDDDRDIRELIVDYLEKSGYRASGAANGKAMWSVLKNHQIDLIVLDIMMPG
CCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEEECC
EDGLTLCRQLRANPQQDIPVLMLTARTDDSDRILGLEMGADDYLIKPFVARELLARIKAI
CCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
LRRTRALPPNLQITETGRLIAFGDWLLDTAARHLLDDSGAIVALSGAEYRLLRVFLDHPQ
HHHHHCCCCCCEEECCCCEEEEHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCHH
RVLNRDQLLNLTQGRDAELFERSIDLLVSRLRQRLREDAREPAYIKTVRSEGYVLSVPVS
HHHCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECHH
IRERHE
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]