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The map label for this gene is fabF [H]

Identifier: 238894813

GI number: 238894813

Start: 2694673

End: 2695947

Strand: Direct

Name: fabF [H]

Synonym: KP1_2826

Alternate gene names: 238894813

Gene position: 2694673-2695947 (Clockwise)

Preceding gene: 238894812

Following gene: 238894814

Centisome position: 51.34

GC content: 65.41

Gene sequence:

>1275_bases
ATGGGCGTTTCCGTTAAACGCATTGTCGTCACCGGGATGGGGATTGTCAGCCCGCTGGGCTGCGGCGTACAGCACGTCTG
GCAGTCGCTGCTGGCAGGTAAATCCGGGATCACCCGACTCAGCGAGCAGCTGGTCGCGGATATTCCCTGCAAAGTGGCTG
GCCAGGTGCCGTCCATTGACAGCGATCCGCTGCACGGCTTCGACCCGCTGGCGACCATCCCGGCGAAAGAGCGCAAAAAG
ATGGATCGCTTTATTGAGTTTGCGCTGGTCGCCGCCCGCGAAGCGCTGGCCCAGGCCGGTTGGTCGCCAGCATCCGAGGC
CGAACAGGAACGCACTGCCACGGTGATCGCCACCGGGATCGGCGGGTTCAGCGAGATCGCCAATGCGGTACATACCACCG
ATGAACGCGGGCCGCGTCGTCTCTCGCCGTTCACTATCCCCTCTTTTCTGGCCAACCTGGCCGCCGGGCATGTGTCTATC
GCCCACGGCTTCCGGGGCCCCATCGGCGCGCCGGTCACCGCCTGCGCAGCGGGCGCCCAGGCCATTGGCGATGCGGCGCG
GATGATCCGCAGCGGCGAGGCGGATATTGCCCTCTGCGGCGGCGCGGAAGCGGCAATTCATCGCGTTAGCCTGGCCGGGT
TTGCCGCGGCAAGGGCGCTGTCCAGCGCCTACAGCGACCAGCCGGAAAGCGCATCCCGCCCCTTTGACCGCGACCGCGAT
GGATTTGTGATGGGAGAAGGCGCCGGGCTTATCGTGATCGAGTCGCTGGAGCACGCGCTGGCGCGCGGGGCCACGCCGCT
GGCCGAGCTGGTGGGCTACGGCACCAGCGCAGATGCTTATCACCTGACCGCGGGCCCGGAAGACGGGAACGGCGCACGTC
GGGCCATGGAGATCGCTATTCGCCAGGCCGGGGTGACCGTCGAAGAGATTGACCATATCAACGCCCACGCCACCTCGACG
CAGGTCGGTGATAAAGGTGAACTGGCGGCGATTAAAACGCTGTTTGGCGTCCATCCGGTCGCTATTACCTCGACGAAATC
CGCCACCGGCCATCTGTTAGGCGCGGCCGGCGGGATCGAGGCCATCTTCACCATTCAGGCGCTGCGTGACCAGGTGGTGC
CGCCGACGCTGAACCTGCATCACCCCGATGAAGAGGCGGCAGGTCTCCATCTGGTGGCGCTGCAGGCCCGCCCGCAGAAG
ATGCGTTACGCGCTGTCGAACGGTTTTGGCTTTGGCGGCGTTAACGCCAGCCTGCTGCTGAAACGCTGGGAATAA

Upstream 100 bases:

>100_bases
GATGCGTTCTACCTCATCATGATGGGTTTTTTACTTGCCGCGCTGCTGGTTCCCTTGATGAAAAAGCCGCCGGCACACTG
ATACTACAGGAGAGTTAACT

Downstream 100 bases:

>100_bases
TCGTCAGCTCCCCCGCGGTACTGGCCGACGGGGGATTTCCACCGTTGCGGCTTTTGCCCTGCTGCTGGAGTAAATCAAGT
ACAACGCAATACCCAGGGAG

Product: putative beta-ketoacyl synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MGVSVKRIVVTGMGIVSPLGCGVQHVWQSLLAGKSGITRLSEQLVADIPCKVAGQVPSIDSDPLHGFDPLATIPAKERKK
MDRFIEFALVAAREALAQAGWSPASEAEQERTATVIATGIGGFSEIANAVHTTDERGPRRLSPFTIPSFLANLAAGHVSI
AHGFRGPIGAPVTACAAGAQAIGDAARMIRSGEADIALCGGAEAAIHRVSLAGFAAARALSSAYSDQPESASRPFDRDRD
GFVMGEGAGLIVIESLEHALARGATPLAELVGYGTSADAYHLTAGPEDGNGARRAMEIAIRQAGVTVEEIDHINAHATST
QVGDKGELAAIKTLFGVHPVAITSTKSATGHLLGAAGGIEAIFTIQALRDQVVPPTLNLHHPDEEAAGLHLVALQARPQK
MRYALSNGFGFGGVNASLLLKRWE

Sequences:

>Translated_424_residues
MGVSVKRIVVTGMGIVSPLGCGVQHVWQSLLAGKSGITRLSEQLVADIPCKVAGQVPSIDSDPLHGFDPLATIPAKERKK
MDRFIEFALVAAREALAQAGWSPASEAEQERTATVIATGIGGFSEIANAVHTTDERGPRRLSPFTIPSFLANLAAGHVSI
AHGFRGPIGAPVTACAAGAQAIGDAARMIRSGEADIALCGGAEAAIHRVSLAGFAAARALSSAYSDQPESASRPFDRDRD
GFVMGEGAGLIVIESLEHALARGATPLAELVGYGTSADAYHLTAGPEDGNGARRAMEIAIRQAGVTVEEIDHINAHATST
QVGDKGELAAIKTLFGVHPVAITSTKSATGHLLGAAGGIEAIFTIQALRDQVVPPTLNLHHPDEEAAGLHLVALQARPQK
MRYALSNGFGFGGVNASLLLKRWE
>Mature_423_residues
GVSVKRIVVTGMGIVSPLGCGVQHVWQSLLAGKSGITRLSEQLVADIPCKVAGQVPSIDSDPLHGFDPLATIPAKERKKM
DRFIEFALVAAREALAQAGWSPASEAEQERTATVIATGIGGFSEIANAVHTTDERGPRRLSPFTIPSFLANLAAGHVSIA
HGFRGPIGAPVTACAAGAQAIGDAARMIRSGEADIALCGGAEAAIHRVSLAGFAAARALSSAYSDQPESASRPFDRDRDG
FVMGEGAGLIVIESLEHALARGATPLAELVGYGTSADAYHLTAGPEDGNGARRAMEIAIRQAGVTVEEIDHINAHATSTQ
VGDKGELAAIKTLFGVHPVAITSTKSATGHLLGAAGGIEAIFTIQALRDQVVPPTLNLHHPDEEAAGLHLVALQARPQKM
RYALSNGFGFGGVNASLLLKRWE

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=419, Percent_Identity=44.8687350835322, Blast_Score=327, Evalue=1e-89,
Organism=Homo sapiens, GI223972627, Length=172, Percent_Identity=46.5116279069767, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI41872631, Length=433, Percent_Identity=26.3279445727483, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI1787337, Length=424, Percent_Identity=45.9905660377358, Blast_Score=344, Evalue=8e-96,
Organism=Escherichia coli, GI1788663, Length=423, Percent_Identity=38.2978723404255, Blast_Score=244, Evalue=5e-66,
Organism=Caenorhabditis elegans, GI71983541, Length=422, Percent_Identity=39.8104265402844, Blast_Score=267, Evalue=8e-72,
Organism=Caenorhabditis elegans, GI71983535, Length=265, Percent_Identity=45.6603773584906, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI212642053, Length=427, Percent_Identity=25.5269320843091, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17550940, Length=287, Percent_Identity=24.390243902439, Blast_Score=89, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6320904, Length=455, Percent_Identity=40, Blast_Score=309, Evalue=5e-85,
Organism=Drosophila melanogaster, GI24644341, Length=422, Percent_Identity=45.0236966824645, Blast_Score=348, Evalue=6e-96,
Organism=Drosophila melanogaster, GI19920632, Length=428, Percent_Identity=24.5327102803738, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221330659, Length=428, Percent_Identity=24.5327102803738, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24581345, Length=426, Percent_Identity=22.5352112676056, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43990; Mature: 43859

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVSVKRIVVTGMGIVSPLGCGVQHVWQSLLAGKSGITRLSEQLVADIPCKVAGQVPSID
CCCCEEEHEEECCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHCCCCCCCC
SDPLHGFDPLATIPAKERKKMDRFIEFALVAAREALAQAGWSPASEAEQERTATVIATGI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEEECC
GGFSEIANAVHTTDERGPRRLSPFTIPSFLANLAAGHVSIAHGFRGPIGAPVTACAAGAQ
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHHHHH
AIGDAARMIRSGEADIALCGGAEAAIHRVSLAGFAAARALSSAYSDQPESASRPFDRDRD
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GFVMGEGAGLIVIESLEHALARGATPLAELVGYGTSADAYHLTAGPEDGNGARRAMEIAI
CEEEECCCCEEEEHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHH
RQAGVTVEEIDHINAHATSTQVGDKGELAAIKTLFGVHPVAITSTKSATGHLLGAAGGIE
HHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCEEECCCCHH
AIFTIQALRDQVVPPTLNLHHPDEEAAGLHLVALQARPQKMRYALSNGFGFGGVNASLLL
HHHHHHHHHHCCCCCCCCCCCCCCHHCCEEEEEECCCCHHHHHHHHCCCCCCCCCHHHEE
KRWE
EECC
>Mature Secondary Structure 
GVSVKRIVVTGMGIVSPLGCGVQHVWQSLLAGKSGITRLSEQLVADIPCKVAGQVPSID
CCCEEEHEEECCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHCCCCCCCC
SDPLHGFDPLATIPAKERKKMDRFIEFALVAAREALAQAGWSPASEAEQERTATVIATGI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEEECC
GGFSEIANAVHTTDERGPRRLSPFTIPSFLANLAAGHVSIAHGFRGPIGAPVTACAAGAQ
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHHHHH
AIGDAARMIRSGEADIALCGGAEAAIHRVSLAGFAAARALSSAYSDQPESASRPFDRDRD
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GFVMGEGAGLIVIESLEHALARGATPLAELVGYGTSADAYHLTAGPEDGNGARRAMEIAI
CEEEECCCCEEEEHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHH
RQAGVTVEEIDHINAHATSTQVGDKGELAAIKTLFGVHPVAITSTKSATGHLLGAAGGIE
HHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCEEECCCCHH
AIFTIQALRDQVVPPTLNLHHPDEEAAGLHLVALQARPQKMRYALSNGFGFGGVNASLLL
HHHHHHHHHHCCCCCCCCCCCCCCHHCCEEEEEECCCCHHHHHHHHCCCCCCCCCHHHEE
KRWE
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10784042; 11481430 [H]