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The map label for this gene is lpfB [H]

Identifier: 238894712

GI number: 238894712

Start: 2597377

End: 2598072

Strand: Reverse

Name: lpfB [H]

Synonym: KP1_2718

Alternate gene names: 238894712

Gene position: 2598072-2597377 (Counterclockwise)

Preceding gene: 238894713

Following gene: 238894711

Centisome position: 49.5

GC content: 55.75

Gene sequence:

>696_bases
ATGCAGTGTTATAAAGCGGCTTTTATCCTGAGCCTTCTCTTTTGCCCGTTCCTGGCGTCTGCCGCCGGGGTTGCCATTGC
CGGCACACGTGTCATTTATAATGAACAAAGCCATGAGGCAGACATCACGGTAAAAAACACCAATCCTCACGATCCGGTGC
TTATTCAGAGCTGGGTAGACGATCTGGCTGATAATAATAAATCACCGTTTATCGTCACCCCACCATTGTTCCGTCTGGAT
GCCGGAGACAGCAACGATCTGCGCGTGTTATTAACCTCGGCGCAACTGCCAAACGATCGGGAAAGTTTGTTCACCCTGAA
TATCAAAGTGATCCCTGCCAATACCGCGCCGGCTGGCGAGAACATTCTGCAATTTGCTATTAAGAATCAACTGAAGCTCA
TTTATCGCCCGGCAGGGCTCCCTGGCTCGGCGCTCGACGCGGCGCAGCACCTGCGCTGGCGGGTCAGCGACAACCACCTG
CAGGCGGAGAATGCCTCCCCCTATTATGTGACTATCACCACGCTCACCTGCGCGGGCCAGAACCAGAAAACGCCGCTTGA
GCGCAGCGTGATTGCTCCTCACAGCCGTGAAGAGTATTCCCTCCCCGGCGAGGCCTGCGACCGCGAGGTGAGCTGGCGCA
TTCTGGATGACTTTGGCGCTGTGCAGACGTTTAGCGCCCCCGTTTCGGCGCACTAA

Upstream 100 bases:

>100_bases
AATATTGATATTGTGTACGAATAGAATGTCCTGATTGCCACTTTTCCAAGGGCAGCGTCCCCCTGCCCTTATTCTCTTCC
TCGTGACCGGATCCTCAATT

Downstream 100 bases:

>100_bases
GCGTCTGATGTCGCGATGCGCCACGGCCCGGCTCATACCGTTACCATCGTCAGCCTCTCCATCCTGCTGGGCGGACAGAG
CGCGCTCTTGCACGCCCAGG

Product: putative fimbrial chaperone protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MQCYKAAFILSLLFCPFLASAAGVAIAGTRVIYNEQSHEADITVKNTNPHDPVLIQSWVDDLADNNKSPFIVTPPLFRLD
AGDSNDLRVLLTSAQLPNDRESLFTLNIKVIPANTAPAGENILQFAIKNQLKLIYRPAGLPGSALDAAQHLRWRVSDNHL
QAENASPYYVTITTLTCAGQNQKTPLERSVIAPHSREEYSLPGEACDREVSWRILDDFGAVQTFSAPVSAH

Sequences:

>Translated_231_residues
MQCYKAAFILSLLFCPFLASAAGVAIAGTRVIYNEQSHEADITVKNTNPHDPVLIQSWVDDLADNNKSPFIVTPPLFRLD
AGDSNDLRVLLTSAQLPNDRESLFTLNIKVIPANTAPAGENILQFAIKNQLKLIYRPAGLPGSALDAAQHLRWRVSDNHL
QAENASPYYVTITTLTCAGQNQKTPLERSVIAPHSREEYSLPGEACDREVSWRILDDFGAVQTFSAPVSAH
>Mature_231_residues
MQCYKAAFILSLLFCPFLASAAGVAIAGTRVIYNEQSHEADITVKNTNPHDPVLIQSWVDDLADNNKSPFIVTPPLFRLD
AGDSNDLRVLLTSAQLPNDRESLFTLNIKVIPANTAPAGENILQFAIKNQLKLIYRPAGLPGSALDAAQHLRWRVSDNHL
QAENASPYYVTITTLTCAGQNQKTPLERSVIAPHSREEYSLPGEACDREVSWRILDDFGAVQTFSAPVSAH

Specific function: Required for the biogenesis of long polar fimbria; binds and interact with lpfA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1789532, Length=218, Percent_Identity=38.0733944954128, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1790771, Length=221, Percent_Identity=37.5565610859729, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1787171, Length=212, Percent_Identity=36.3207547169811, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1786743, Length=216, Percent_Identity=31.0185185185185, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786333, Length=229, Percent_Identity=32.3144104803493, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788428, Length=229, Percent_Identity=31.4410480349345, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI87081806, Length=222, Percent_Identity=32.8828828828829, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI87082203, Length=221, Percent_Identity=28.0542986425339, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1786936, Length=220, Percent_Identity=29.5454545454545, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1788677, Length=150, Percent_Identity=34, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789609, Length=201, Percent_Identity=27.363184079602, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 25354; Mature: 25354

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCYKAAFILSLLFCPFLASAAGVAIAGTRVIYNEQSHEADITVKNTNPHDPVLIQSWVD
CCHHHHHHHHHHHHHHHHHHHCCEEEECEEEEECCCCCCCEEEECCCCCCCCEEHHHHHH
DLADNNKSPFIVTPPLFRLDAGDSNDLRVLLTSAQLPNDRESLFTLNIKVIPANTAPAGE
HHHCCCCCCEEECCCCEEECCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCH
NILQFAIKNQLKLIYRPAGLPGSALDAAQHLRWRVSDNHLQAENASPYYVTITTLTCAGQ
HHHHHHHHHCEEEEEECCCCCCHHHHHHHHHEEEECCCEEECCCCCCEEEEEEEEEECCC
NQKTPLERSVIAPHSREEYSLPGEACDREVSWRILDDFGAVQTFSAPVSAH
CCCCCCHHHEECCCCCCCCCCCHHHCCCCCEEEEECCCCCCEEECCCCCCC
>Mature Secondary Structure
MQCYKAAFILSLLFCPFLASAAGVAIAGTRVIYNEQSHEADITVKNTNPHDPVLIQSWVD
CCHHHHHHHHHHHHHHHHHHHCCEEEECEEEEECCCCCCCEEEECCCCCCCCEEHHHHHH
DLADNNKSPFIVTPPLFRLDAGDSNDLRVLLTSAQLPNDRESLFTLNIKVIPANTAPAGE
HHHCCCCCCEEECCCCEEECCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCH
NILQFAIKNQLKLIYRPAGLPGSALDAAQHLRWRVSDNHLQAENASPYYVTITTLTCAGQ
HHHHHHHHHCEEEEEECCCCCCHHHHHHHHHEEEECCCEEECCCCCCEEEEEEEEEECCC
NQKTPLERSVIAPHSREEYSLPGEACDREVSWRILDDFGAVQTFSAPVSAH
CCCCCCHHHEECCCCCCCCCCCHHHCCCCCEEEEECCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721701; 11677609 [H]