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The map label for this gene is mrkD [H]

Identifier: 238894710

GI number: 238894710

Start: 2593868

End: 2594872

Strand: Reverse

Name: mrkD [H]

Synonym: KP1_2716

Alternate gene names: 238894710

Gene position: 2594872-2593868 (Counterclockwise)

Preceding gene: 238894711

Following gene: 238894709

Centisome position: 49.44

GC content: 63.38

Gene sequence:

>1005_bases
ATGTCCTTTTTAACTCTCCTGCGTCGGGTCGCCCTGACGCTGTTATTCACTCTGTTACCGGCCGCCAGCGGATGGGCCTG
TACGCCAGTGTTTGTCCGCGGCCAGGCCTCCACCCTTCGGCTGAACGTGGGGCAGCTCACGGTTCCGGCTGACGCCAGAC
CCGGCACCCCGCTGTATCATAAAAGTTTCGCCTGGAACCGCCTTAGCGACGGCGGCGAACAGTGGATCCGCTGCGCGGAC
GACCCGCACGGGCTGTCGCCGCTGCTGCTGGACAGTCTGCTGTCCGGGGGAGTGACGCGACCGACGGTTTATCAAACTAA
TCTCGCCGGCATTGGCGTTCGCGTATCGCTGCGCGCTATCGGCAGCTATGGCGGCTTTCCTGACCGGCCGACGCCCTCGC
CGTTTAGCCAACGGGTGGACAATCCCGCCGCCTTGCCCGATGCGGTGTGGAAACTGGGCTATTTCCGCCTGACGATTGAG
CTCATTAAAACCGGTCCCGCGGCGACGCCGGGCGAGCTTGAGTATCACAGCGAGCGCTTTTTAATAGCGGAGCATACCCC
GCTGGCCGCGTTAGACTTAACCGGCAGGATCAGCACCGCGGGATGTTCAGTGAATGACGCCACGCCAGCCCTGATCAAGC
TCCCTGCGGCGATGCTTGACCACTTCGGTGGCGTCGGCAAAACCACCGGCGACACCCCTTTCGCGCTGCAGCTGGATTGC
AACAGCGCGGTCACGGTTTCCCTGCGAGTTGACGGCGCGGAGCCCCTCTCCGCCCGGGGGCATGGCGTTCTGCGCAATGA
CGCCACCGACGATCGGGCGCAGGGTATTGGCGTGCAGTTGCTTTACCATCGTCAGCCGGTCGTACTGAATCATGAGATGA
CGCTGGGCAGCGCGAGCGCGGGCCGGTTTACCCTGCCGCTCACTGCCCGCTACTACCAGACACGTTCCCGGATCACCGCC
GGTCAGGTGTCGGCCGTCGCGACCTATACCTTGCATTATGACTAG

Upstream 100 bases:

>100_bases
AATGGGGGCCAGGCCCTCAGCAGCGCTGTAGCGCCCGCTACGATCTCACCCCGACGCTGGCGCAGACCCCCCATCCACTC
ATCTTACAGCAGACGTTATC

Downstream 100 bases:

>100_bases
GCGATGGCGAACCGACGGATGAAGCGGATGAAGGAATTGCTCTGACCGGCGAATCGTAAGAGAATAGCGCCTACACGCGA
CGATCTGAGTACACGGGAGT

Product: fimbrial protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MSFLTLLRRVALTLLFTLLPAASGWACTPVFVRGQASTLRLNVGQLTVPADARPGTPLYHKSFAWNRLSDGGEQWIRCAD
DPHGLSPLLLDSLLSGGVTRPTVYQTNLAGIGVRVSLRAIGSYGGFPDRPTPSPFSQRVDNPAALPDAVWKLGYFRLTIE
LIKTGPAATPGELEYHSERFLIAEHTPLAALDLTGRISTAGCSVNDATPALIKLPAAMLDHFGGVGKTTGDTPFALQLDC
NSAVTVSLRVDGAEPLSARGHGVLRNDATDDRAQGIGVQLLYHRQPVVLNHEMTLGSASAGRFTLPLTARYYQTRSRITA
GQVSAVATYTLHYD

Sequences:

>Translated_334_residues
MSFLTLLRRVALTLLFTLLPAASGWACTPVFVRGQASTLRLNVGQLTVPADARPGTPLYHKSFAWNRLSDGGEQWIRCAD
DPHGLSPLLLDSLLSGGVTRPTVYQTNLAGIGVRVSLRAIGSYGGFPDRPTPSPFSQRVDNPAALPDAVWKLGYFRLTIE
LIKTGPAATPGELEYHSERFLIAEHTPLAALDLTGRISTAGCSVNDATPALIKLPAAMLDHFGGVGKTTGDTPFALQLDC
NSAVTVSLRVDGAEPLSARGHGVLRNDATDDRAQGIGVQLLYHRQPVVLNHEMTLGSASAGRFTLPLTARYYQTRSRITA
GQVSAVATYTLHYD
>Mature_333_residues
SFLTLLRRVALTLLFTLLPAASGWACTPVFVRGQASTLRLNVGQLTVPADARPGTPLYHKSFAWNRLSDGGEQWIRCADD
PHGLSPLLLDSLLSGGVTRPTVYQTNLAGIGVRVSLRAIGSYGGFPDRPTPSPFSQRVDNPAALPDAVWKLGYFRLTIEL
IKTGPAATPGELEYHSERFLIAEHTPLAALDLTGRISTAGCSVNDATPALIKLPAAMLDHFGGVGKTTGDTPFALQLDCN
SAVTVSLRVDGAEPLSARGHGVLRNDATDDRAQGIGVQLLYHRQPVVLNHEMTLGSASAGRFTLPLTARYYQTRSRITAG
QVSAVATYTLHYD

Specific function: Involved In Regulation Of Length And Mediation Of Adhesion Of Type 1 Fimbriae (But Not Necessary For The Production Of Fimbriae). Involved In The Integration Of Fimh In The Fimbriae. [C]

COG id: COG3539

COG function: function code NU; P pilus assembly protein, pilin FimA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966
- InterPro:   IPR000259
- InterPro:   IPR014779 [H]

Pfam domain/function: PF00419 Fimbrial [H]

EC number: NA

Molecular weight: Translated: 35785; Mature: 35654

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLTLLRRVALTLLFTLLPAASGWACTPVFVRGQASTLRLNVGQLTVPADARPGTPLYH
CHHHHHHHHHHHHHHHHHHCCCCCCEECEEEEECCCEEEEEECCEEEECCCCCCCCCCEE
KSFAWNRLSDGGEQWIRCADDPHGLSPLLLDSLLSGGVTRPTVYQTNLAGIGVRVSLRAI
CCCCCCCCCCCCHHHEEECCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEEE
GSYGGFPDRPTPSPFSQRVDNPAALPDAVWKLGYFRLTIELIKTGPAATPGELEYHSERF
ECCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHEEEEEEEEECCCCCCCCCEEECCCEE
LIAEHTPLAALDLTGRISTAGCSVNDATPALIKLPAAMLDHFGGVGKTTGDTPFALQLDC
EEEECCCEEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
NSAVTVSLRVDGAEPLSARGHGVLRNDATDDRAQGIGVQLLYHRQPVVLNHEMTLGSASA
CCEEEEEEEECCCCCCCCCCCEEECCCCCCHHHCCCCEEEEEECCCEEEECEEECCCCCC
GRFTLPLTARYYQTRSRITAGQVSAVATYTLHYD
CEEEEEEHHHHHHHHHCCCCCCEEEEEEEEEEEC
>Mature Secondary Structure 
SFLTLLRRVALTLLFTLLPAASGWACTPVFVRGQASTLRLNVGQLTVPADARPGTPLYH
HHHHHHHHHHHHHHHHHHCCCCCCEECEEEEECCCEEEEEECCEEEECCCCCCCCCCEE
KSFAWNRLSDGGEQWIRCADDPHGLSPLLLDSLLSGGVTRPTVYQTNLAGIGVRVSLRAI
CCCCCCCCCCCCHHHEEECCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEEE
GSYGGFPDRPTPSPFSQRVDNPAALPDAVWKLGYFRLTIELIKTGPAATPGELEYHSERF
ECCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHEEEEEEEEECCCCCCCCCEEECCCEE
LIAEHTPLAALDLTGRISTAGCSVNDATPALIKLPAAMLDHFGGVGKTTGDTPFALQLDC
EEEECCCEEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
NSAVTVSLRVDGAEPLSARGHGVLRNDATDDRAQGIGVQLLYHRQPVVLNHEMTLGSASA
CCEEEEEEEECCCCCCCCCCCEEECCCCCCHHHCCCCEEEEEECCCEEEECEEECCCCCC
GRFTLPLTARYYQTRSRITAGQVSAVATYTLHYD
CEEEEEEHHHHHHHHHCCCCCCEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1670938; 2563996 [H]