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The map label for this gene is marC [H]

Identifier: 238894657

GI number: 238894657

Start: 2546672

End: 2547340

Strand: Direct

Name: marC [H]

Synonym: KP1_2662

Alternate gene names: 238894657

Gene position: 2546672-2547340 (Clockwise)

Preceding gene: 238894656

Following gene: 238894659

Centisome position: 48.52

GC content: 55.75

Gene sequence:

>669_bases
ATGTTCGATTTGTTTAAAGCAATAGGGCTCGGCCTGGCGGTGCTTTTACCGCTGGCGAATCCACTCACAACCGTGGCGCT
GTTCCTTGGCCTGGCCGGTAATATGAACAACGCCGAGCGTAATAAACAGGCGTTAATGGCATCGGTGTATGTCTTCGCCA
TCCTGATGGTGTCGTGGTATGCCGGTCAGGTGGTGATGAATACATTCGGCATATCAATACCTGGGCTGCGTATCGCCGGC
GGATTGATTGTGGCCTTTATCGGTTTCCGCATGCTGTTTCCCCAGCAAAAAGCCCACGATTCGATGGAAGCGAAGATCAA
ATCGGAAGAACTGCAGGATGAACCGACCGCCAATATCGCCTTTGTGCCGCTGGCGATGCCAAGCACCGCCGGTCCGGGCA
CCATCGCGATGATTATTAGCTCCGCCTCGACCGTTAAGCACGGCGTGGACTTCCCGGAGTGGGTGGTGCTGGCGGCGCCG
CCGATCATCTTTTTGCTGTTAGGGGTGATTCTGTGGGCTTGTCTGCGCAGTTCCGGCGCGATTATGCGTCTGGTTGGCAA
AGGCGGCATCGAGGCCATCTCGCGACTGATGGGCTTTCTGCTGGTCTGCATGGGCGTGCAGTTTATTATTAACGGCGTGC
TGGAGATCATTTCGACCTGGCATCCCTGA

Upstream 100 bases:

>100_bases
GTGATTTATCAGCAGGCTGGCGTCAAATTTGTTGAAGCCGATATACTCACGGAATGAAACCATTCTTAAAAAATGAATAT
TAACGGGACTTTAATTAACT

Downstream 100 bases:

>100_bases
CCGCCCGCGATGCGCAGAGAAAAAAAGCCCGCCGGCGCGATACCGGCGGGCTTTTTTGTGCGACGGAATCAGGAGTGGTG
CGGCTGATGGTCTTCCAGCG

Product: multiple drug resistance protein MarC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MFDLFKAIGLGLAVLLPLANPLTTVALFLGLAGNMNNAERNKQALMASVYVFAILMVSWYAGQVVMNTFGISIPGLRIAG
GLIVAFIGFRMLFPQQKAHDSMEAKIKSEELQDEPTANIAFVPLAMPSTAGPGTIAMIISSASTVKHGVDFPEWVVLAAP
PIIFLLLGVILWACLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIISTWHP

Sequences:

>Translated_222_residues
MFDLFKAIGLGLAVLLPLANPLTTVALFLGLAGNMNNAERNKQALMASVYVFAILMVSWYAGQVVMNTFGISIPGLRIAG
GLIVAFIGFRMLFPQQKAHDSMEAKIKSEELQDEPTANIAFVPLAMPSTAGPGTIAMIISSASTVKHGVDFPEWVVLAAP
PIIFLLLGVILWACLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIISTWHP
>Mature_222_residues
MFDLFKAIGLGLAVLLPLANPLTTVALFLGLAGNMNNAERNKQALMASVYVFAILMVSWYAGQVVMNTFGISIPGLRIAG
GLIVAFIGFRMLFPQQKAHDSMEAKIKSEELQDEPTANIAFVPLAMPSTAGPGTIAMIISSASTVKHGVDFPEWVVLAAP
PIIFLLLGVILWACLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIISTWHP

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787809, Length=221, Percent_Identity=84.6153846153846, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI1787494, Length=199, Percent_Identity=32.6633165829146, Blast_Score=101, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 23728; Mature: 23728

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDLFKAIGLGLAVLLPLANPLTTVALFLGLAGNMNNAERNKQALMASVYVFAILMVSWY
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AGQVVMNTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAHDSMEAKIKSEELQDEPTANIA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEE
FVPLAMPSTAGPGTIAMIISSASTVKHGVDFPEWVVLAAPPIIFLLLGVILWACLRSSGA
EEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCC
IMRLVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIISTWHP
EEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFDLFKAIGLGLAVLLPLANPLTTVALFLGLAGNMNNAERNKQALMASVYVFAILMVSWY
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AGQVVMNTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAHDSMEAKIKSEELQDEPTANIA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEE
FVPLAMPSTAGPGTIAMIISSASTVKHGVDFPEWVVLAAPPIIFLLLGVILWACLRSSGA
EEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCC
IMRLVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIISTWHP
EEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA