BacMap

Definition	Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome.
Accession	NC_012731
Length	5,248,520

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The map label for this gene is ydfG [H]

Identifier: 238894612

GI number: 238894612

Start: 2506645

End: 2507409

Strand: Reverse

Name: ydfG [H]

Synonym: KP1_2613

Alternate gene names: 238894612

Gene position: 2507409-2506645 (Counterclockwise)

Preceding gene: 238894614

Following gene: 238894611

Centisome position: 47.77

GC content: 57.91

Gene sequence:

>765_bases
TTGAGGAACAGTAAGATGATTATCATGGTCACCGGCGCCACCGCCGGTTTTGGTGAAAGTATTACTCGCCGTTTTATCGC
TAACGGTCATAAAGTGATTGCCACCGGTCGTCGTGAAGAGCGCCTGAAGACGCTGAAAGACGAGCTGGGCGATAACCTTT
ATATCGCGCAACTTGACGTCCGCAACCGCGCCGCCATTGAGACGCTGATTGCTGACCTGCCGGCCGAGTGGCAGGCTATC
GATGTGCTGGTGAACAACGCCGGCCTGGCGCTTGGTCTGGAGCCGGCGCACCGCGCCAGTGTGGAAGACTGGGAAGATAT
GATCGACACCAATAATAAAGGGCTGGTGTACATGACCCGCGCCGTGCTGCCGGGGATGGTGGAGCGCAATCGCGGCCATA
TCATCAATATCGGCTCTACGGCAGGCAGCTGGCCTTACGCCGGCGGAAACGTCTATGGGGCGACCAAAGCCTTTGTCCGT
CAGTTTAGCCTCAATCTTCGTACCGACCTGCACGGCACCGCGGTGCGCGTGACCGACATCGAGCCGGGTCTGGTGGGCGG
CACCGAGTTTTCTAACGTCCGCTTTAAGGGCGATGACGCTAAAGCCGAAAAAGCTTACGAAAATACCCAAGCGCTAACGC
CGGAAGATGTGACCGAGGCGGTCTGGTGGGTCGCCACCCTGCCGAAACATGTCAACATCAACACCCTGGAGATGATGCCG
GTGAGTCAGAGCTTTGCCGGACTCAGCGTTCACCGTCAGGGCTAA

Upstream 100 bases:

>100_bases
AGGCTAATGCTGTAAGATTAGGCCTCTCCTTAAGGGGTCGCAATGATTTCCGTTACCGGTCGCCGCCTGTGCGTGCTATG
GTATGAAAACACAAAAAGCG

Downstream 100 bases:

>100_bases
CCGTCAGCCACCCGGCCTGCGGGCCGGGTATGGGCGGAAACGCAAAAAACGCGTAAAATAGTGCGCATAACCCCCTAAAA
AGTAACCATCAATGGCCGCA

Product: 3-hydroxy acid dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MRNSKMIIMVTGATAGFGESITRRFIANGHKVIATGRREERLKTLKDELGDNLYIAQLDVRNRAAIETLIADLPAEWQAI
DVLVNNAGLALGLEPAHRASVEDWEDMIDTNNKGLVYMTRAVLPGMVERNRGHIINIGSTAGSWPYAGGNVYGATKAFVR
QFSLNLRTDLHGTAVRVTDIEPGLVGGTEFSNVRFKGDDAKAEKAYENTQALTPEDVTEAVWWVATLPKHVNINTLEMMP
VSQSFAGLSVHRQG

Sequences:

>Translated_254_residues
MRNSKMIIMVTGATAGFGESITRRFIANGHKVIATGRREERLKTLKDELGDNLYIAQLDVRNRAAIETLIADLPAEWQAI
DVLVNNAGLALGLEPAHRASVEDWEDMIDTNNKGLVYMTRAVLPGMVERNRGHIINIGSTAGSWPYAGGNVYGATKAFVR
QFSLNLRTDLHGTAVRVTDIEPGLVGGTEFSNVRFKGDDAKAEKAYENTQALTPEDVTEAVWWVATLPKHVNINTLEMMP
VSQSFAGLSVHRQG
>Mature_254_residues
MRNSKMIIMVTGATAGFGESITRRFIANGHKVIATGRREERLKTLKDELGDNLYIAQLDVRNRAAIETLIADLPAEWQAI
DVLVNNAGLALGLEPAHRASVEDWEDMIDTNNKGLVYMTRAVLPGMVERNRGHIINIGSTAGSWPYAGGNVYGATKAFVR
QFSLNLRTDLHGTAVRVTDIEPGLVGGTEFSNVRFKGDDAKAEKAYENTQALTPEDVTEAVWWVATLPKHVNINTLEMMP
VSQSFAGLSVHRQG

Specific function: Catalyzes the NADP-dependent oxidation of L-allo- threonine and L-serine [H]

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=33.4677419354839, Blast_Score=124, Evalue=6e-29,
Organism=Homo sapiens, GI20149619, Length=199, Percent_Identity=29.6482412060301, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI7657478, Length=245, Percent_Identity=29.3877551020408, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI7705855, Length=199, Percent_Identity=31.6582914572864, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI150247226, Length=195, Percent_Identity=31.2820512820513, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI22507405, Length=187, Percent_Identity=31.5508021390374, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI40548397, Length=184, Percent_Identity=33.1521739130435, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI214010158, Length=184, Percent_Identity=33.1521739130435, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI214010156, Length=184, Percent_Identity=33.1521739130435, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI22758144, Length=184, Percent_Identity=33.1521739130435, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI19923817, Length=188, Percent_Identity=29.2553191489362, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=30.2083333333333, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI157739938, Length=187, Percent_Identity=24.5989304812834, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI19743808, Length=183, Percent_Identity=29.5081967213115, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI32483357, Length=232, Percent_Identity=26.2931034482759, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI4557649, Length=179, Percent_Identity=29.0502793296089, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4758504, Length=192, Percent_Identity=26.5625, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI44680136, Length=184, Percent_Identity=29.3478260869565, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI44680133, Length=184, Percent_Identity=29.3478260869565, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI17738292, Length=184, Percent_Identity=29.3478260869565, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI5031737, Length=207, Percent_Identity=27.0531400966184, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI119392083, Length=222, Percent_Identity=25.6756756756757, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=27.3684210526316, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787820, Length=248, Percent_Identity=88.3064516129032, Blast_Score=462, Evalue=1e-132,
Organism=Escherichia coli, GI1787335, Length=196, Percent_Identity=33.6734693877551, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI87082100, Length=181, Percent_Identity=33.7016574585635, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786812, Length=198, Percent_Identity=26.2626262626263, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790717, Length=179, Percent_Identity=26.8156424581006, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787526, Length=224, Percent_Identity=24.1071428571429, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=239, Percent_Identity=28.8702928870293, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=236, Percent_Identity=25.4237288135593, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=245, Percent_Identity=26.9387755102041, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=235, Percent_Identity=25.9574468085106, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=253, Percent_Identity=27.6679841897233, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=247, Percent_Identity=25.1012145748988, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=246, Percent_Identity=26.8292682926829, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=248, Percent_Identity=25.4032258064516, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=192, Percent_Identity=28.6458333333333, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=229, Percent_Identity=24.8908296943231, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=196, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25152911, Length=215, Percent_Identity=28.8372093023256, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=246, Percent_Identity=27.6422764227642, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=200, Percent_Identity=27, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=193, Percent_Identity=27.979274611399, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=218, Percent_Identity=28.8990825688073, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=192, Percent_Identity=27.0833333333333, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=196, Percent_Identity=28.0612244897959, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI212646214, Length=222, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17557780, Length=202, Percent_Identity=27.2277227722772, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=227, Percent_Identity=26.431718061674, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=220, Percent_Identity=26.8181818181818, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560176, Length=194, Percent_Identity=27.8350515463918, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=238, Percent_Identity=24.7899159663866, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=251, Percent_Identity=36.6533864541833, Blast_Score=162, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6322227, Length=199, Percent_Identity=27.6381909547739, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322067, Length=180, Percent_Identity=31.6666666666667, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322226, Length=190, Percent_Identity=25.2631578947368, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319635, Length=204, Percent_Identity=27.4509803921569, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI116007236, Length=253, Percent_Identity=32.0158102766798, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281364494, Length=251, Percent_Identity=28.6852589641434, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI23397609, Length=186, Percent_Identity=32.7956989247312, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21358495, Length=223, Percent_Identity=28.6995515695067, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24641388, Length=252, Percent_Identity=29.3650793650794, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24640442, Length=207, Percent_Identity=30.9178743961353, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI28571526, Length=235, Percent_Identity=30.6382978723404, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24643142, Length=179, Percent_Identity=30.7262569832402, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI116007238, Length=186, Percent_Identity=32.258064516129, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24648693, Length=251, Percent_Identity=28.2868525896414, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355889, Length=251, Percent_Identity=28.2868525896414, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24663911, Length=252, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571387, Length=252, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI161076933, Length=181, Percent_Identity=29.2817679558011, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24584748, Length=181, Percent_Identity=29.2817679558011, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641232, Length=255, Percent_Identity=27.4509803921569, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI116007234, Length=253, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357041, Length=183, Percent_Identity=27.8688524590164, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24644339, Length=231, Percent_Identity=26.4069264069264, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648944, Length=236, Percent_Identity=25.8474576271186, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584744, Length=186, Percent_Identity=28.494623655914, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28574402, Length=186, Percent_Identity=28.494623655914, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17737361, Length=191, Percent_Identity=28.7958115183246, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24639444, Length=237, Percent_Identity=27.4261603375527, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27846; Mature: 27846

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNSKMIIMVTGATAGFGESITRRFIANGHKVIATGRREERLKTLKDELGDNLYIAQLDV
CCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECC
RNRAAIETLIADLPAEWQAIDVLVNNAGLALGLEPAHRASVEDWEDMIDTNNKGLVYMTR
CCHHHHHHHHHHCCCCCEEEEEEEECCCEEEECCCHHHCCHHHHHHHHCCCCCCEEEEHH
AVLPGMVERNRGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTAVRVTDI
HHCCHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEEC
EPGLVGGTEFSNVRFKGDDAKAEKAYENTQALTPEDVTEAVWWVATLPKHVNINTLEMMP
CCCCCCCCCCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEE
VSQSFAGLSVHRQG
CCCCCCCCEEEECC
>Mature Secondary Structure
MRNSKMIIMVTGATAGFGESITRRFIANGHKVIATGRREERLKTLKDELGDNLYIAQLDV
CCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECC
RNRAAIETLIADLPAEWQAIDVLVNNAGLALGLEPAHRASVEDWEDMIDTNNKGLVYMTR
CCHHHHHHHHHHCCCCCEEEEEEEECCCEEEECCCHHHCCHHHHHHHHCCCCCCEEEEHH
AVLPGMVERNRGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTAVRVTDI
HHCCHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEEC
EPGLVGGTEFSNVRFKGDDAKAEKAYENTQALTPEDVTEAVWWVATLPKHVNINTLEMMP
CCCCCCCCCCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEE
VSQSFAGLSVHRQG
CCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]