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The map label for this gene is gapA [H]

Identifier: 238894517

GI number: 238894517

Start: 2414657

End: 2415655

Strand: Reverse

Name: gapA [H]

Synonym: KP1_2510

Alternate gene names: 238894517

Gene position: 2415655-2414657 (Counterclockwise)

Preceding gene: 238894519

Following gene: 238894515

Centisome position: 46.03

GC content: 57.56

Gene sequence:

>999_bases
ATGAGTAAACTTGGGATTAATGGATTTGGTCGTATCGGACGTCTGGTGTTACGTCGTTTATTAGAAGTCGACAGCAGCCT
GGAAGTGGTGGCTATCAACGACCTCACTTCGCCAAAGGTGCTGGCCTACCTGTTGAAGCATGATTCAAACTACGGCCCCT
TCCCGTGGAGCGTCGACTTTACCGAAGATGCGCTGATCGTCAACGGCAAAACCATTACGGTGTATGCCGAAAAAGAGGCG
CAGCATATTCCATGGCAGGCGGCAGGCGCCGAGGTGATTGTGGAGTGTACCGGGTTCTACACCTCGGCTGAGAAATCGCA
AGCCCATCTCCAGGCCGGCGCGCGCAAAGTGCTGATTTCCGCCCCCGCCGGCGAGATGAAAACCATCGTCTACAACGTCA
ACGATGACACCCTGACCCCGGATGACACCATCATCTCCGTGGCCTCCTGCACCACCAACTGCCTGGCGCCGATGGCCAAA
GTTCTGCAGGATGCCTTCGGCATCACCGTAGGCACCATGACCACCATCCACGCCTATACCGGCACCCAGTCGCTGGTGGA
CGGGCCGCGCGGTAAAGATCTGCGCGCCTCCAGGGCGGCGGCGGAAAACGTTATCCCGCACACTACCGGCGCGGCAAAAG
CCATTGGCCTGGTGATCCCTGCCCTGAGCGGTAAGCTGAAAGGCCATGCCCAGCGCGTACCGACCAAAACCGGCTCAGTG
ACGGAGCTGGTATCGGTGCTGGAGAAAAAGGTGACTGCGGATGAGGTCAATCAGGCGATGAGGCAGGCGGCTGAGGGCAA
TGAATCCTTTGGTTACACCGAAGAGGAGATCGTCTCTTCCGATATCATCGGCAGCCATTTCGGTTCGATCTACGATGCTA
CCCAGCTGGAGATTGTGGAGGCCGGCGGCGTACAGCTGGTGAAAACCGTCGCCTGGTACGATAACGAATACGGCTTTGTC
ACCCAACTGATCCGCGTGCTGGAGAAATTTGCCCGCTAA

Upstream 100 bases:

>100_bases
TGGCAAAGCGCACAGATTGTCAGTTGACCAATCAGGGGGACAGGGCTAAGCCTGGAGGAGTTTCATCACATCGAGTCGTT
TTACCAACCGGAGAATATCC

Downstream 100 bases:

>100_bases
GTGAACGGCGGACAGCCTGCGCTGTCCGCCGGTTCTGTGTGGAGTGCCTCAGGCCTGCAGATAGACCACCTGGGTCTGCA
GGTACTCATTCAGGCCGTGG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH-C [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSKLGINGFGRIGRLVLRRLLEVDSSLEVVAINDLTSPKVLAYLLKHDSNYGPFPWSVDFTEDALIVNGKTITVYAEKEA
QHIPWQAAGAEVIVECTGFYTSAEKSQAHLQAGARKVLISAPAGEMKTIVYNVNDDTLTPDDTIISVASCTTNCLAPMAK
VLQDAFGITVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENVIPHTTGAAKAIGLVIPALSGKLKGHAQRVPTKTGSV
TELVSVLEKKVTADEVNQAMRQAAEGNESFGYTEEEIVSSDIIGSHFGSIYDATQLEIVEAGGVQLVKTVAWYDNEYGFV
TQLIRVLEKFAR

Sequences:

>Translated_332_residues
MSKLGINGFGRIGRLVLRRLLEVDSSLEVVAINDLTSPKVLAYLLKHDSNYGPFPWSVDFTEDALIVNGKTITVYAEKEA
QHIPWQAAGAEVIVECTGFYTSAEKSQAHLQAGARKVLISAPAGEMKTIVYNVNDDTLTPDDTIISVASCTTNCLAPMAK
VLQDAFGITVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENVIPHTTGAAKAIGLVIPALSGKLKGHAQRVPTKTGSV
TELVSVLEKKVTADEVNQAMRQAAEGNESFGYTEEEIVSSDIIGSHFGSIYDATQLEIVEAGGVQLVKTVAWYDNEYGFV
TQLIRVLEKFAR
>Mature_331_residues
SKLGINGFGRIGRLVLRRLLEVDSSLEVVAINDLTSPKVLAYLLKHDSNYGPFPWSVDFTEDALIVNGKTITVYAEKEAQ
HIPWQAAGAEVIVECTGFYTSAEKSQAHLQAGARKVLISAPAGEMKTIVYNVNDDTLTPDDTIISVASCTTNCLAPMAKV
LQDAFGITVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENVIPHTTGAAKAIGLVIPALSGKLKGHAQRVPTKTGSVT
ELVSVLEKKVTADEVNQAMRQAAEGNESFGYTEEEIVSSDIIGSHFGSIYDATQLEIVEAGGVQLVKTVAWYDNEYGFVT
QLIRVLEKFAR

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=336, Percent_Identity=44.9404761904762, Blast_Score=286, Evalue=2e-77,
Organism=Homo sapiens, GI7657116, Length=338, Percent_Identity=44.6745562130178, Blast_Score=283, Evalue=1e-76,
Organism=Escherichia coli, GI1788079, Length=337, Percent_Identity=44.8071216617211, Blast_Score=282, Evalue=2e-77,
Organism=Escherichia coli, GI1789295, Length=328, Percent_Identity=40.8536585365854, Blast_Score=241, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=46.1538461538462, Blast_Score=281, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=46.2908011869436, Blast_Score=281, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=46.2908011869436, Blast_Score=281, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=46.1538461538462, Blast_Score=281, Evalue=4e-76,
Organism=Saccharomyces cerevisiae, GI6322409, Length=339, Percent_Identity=45.7227138643068, Blast_Score=298, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6321631, Length=339, Percent_Identity=45.1327433628319, Blast_Score=295, Evalue=5e-81,
Organism=Saccharomyces cerevisiae, GI6322468, Length=339, Percent_Identity=45.1327433628319, Blast_Score=293, Evalue=2e-80,
Organism=Drosophila melanogaster, GI17933600, Length=334, Percent_Identity=47.9041916167665, Blast_Score=301, Evalue=6e-82,
Organism=Drosophila melanogaster, GI18110149, Length=334, Percent_Identity=47.9041916167665, Blast_Score=301, Evalue=6e-82,
Organism=Drosophila melanogaster, GI85725000, Length=334, Percent_Identity=47.6047904191617, Blast_Score=299, Evalue=1e-81,
Organism=Drosophila melanogaster, GI22023983, Length=334, Percent_Identity=47.6047904191617, Blast_Score=299, Evalue=1e-81,
Organism=Drosophila melanogaster, GI19922412, Length=330, Percent_Identity=44.8484848484849, Blast_Score=285, Evalue=4e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35659; Mature: 35528

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLGINGFGRIGRLVLRRLLEVDSSLEVVAINDLTSPKVLAYLLKHDSNYGPFPWSVDF
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEECC
TEDALIVNGKTITVYAEKEAQHIPWQAAGAEVIVECTGFYTSAEKSQAHLQAGARKVLIS
CCCEEEECCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEEE
APAGEMKTIVYNVNDDTLTPDDTIISVASCTTNCLAPMAKVLQDAFGITVGTMTTIHAYT
CCCCCEEEEEEECCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHCCEECCCEEEEEEC
GTQSLVDGPRGKDLRASRAAAENVIPHTTGAAKAIGLVIPALSGKLKGHAQRVPTKTGSV
CCHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCH
TELVSVLEKKVTADEVNQAMRQAAEGNESFGYTEEEIVSSDIIGSHFGSIYDATQLEIVE
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEE
AGGVQLVKTVAWYDNEYGFVTQLIRVLEKFAR
CCCHHEEHHHHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKLGINGFGRIGRLVLRRLLEVDSSLEVVAINDLTSPKVLAYLLKHDSNYGPFPWSVDF
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEECC
TEDALIVNGKTITVYAEKEAQHIPWQAAGAEVIVECTGFYTSAEKSQAHLQAGARKVLIS
CCCEEEECCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEEE
APAGEMKTIVYNVNDDTLTPDDTIISVASCTTNCLAPMAKVLQDAFGITVGTMTTIHAYT
CCCCCEEEEEEECCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHCCEECCCEEEEEEC
GTQSLVDGPRGKDLRASRAAAENVIPHTTGAAKAIGLVIPALSGKLKGHAQRVPTKTGSV
CCHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCH
TELVSVLEKKVTADEVNQAMRQAAEGNESFGYTEEEIVSSDIIGSHFGSIYDATQLEIVE
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEE
AGGVQLVKTVAWYDNEYGFVTQLIRVLEKFAR
CCCHHEEHHHHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]