Click here to switch to the map view.

The map label for this gene is ycaN [H]

Identifier: 238894502

GI number: 238894502

Start: 2398740

End: 2399687

Strand: Reverse

Name: ycaN [H]

Synonym: KP1_2493

Alternate gene names: 238894502

Gene position: 2399687-2398740 (Counterclockwise)

Preceding gene: 238894504

Following gene: 238894501

Centisome position: 45.72

GC content: 51.9

Gene sequence:

>948_bases
ATGAAAACCTTGCCCGATCTGCAACAAATAGAAATATTAATACTCATAGTGAAACATGGCAGTTTTCGTCAGGCCGCTAA
AGCGTTAAACCTTTCCCCACCGGCCCTTACTGTCGCTATTAATCATCTGGAAGAAAAGTTAGGCGTGCGCCTGCTAAATC
GCTCAACGCGCAGTTTGTCATTAACCGCAGTGGGTGAGGAATTTCTTAATAATATAACGCCGGTGGTCAATGATTATCGC
CGGGTGGTGGACAGTCTGAATTATCACCGTCTGACTCCGGAAGGCGTGGTGAAAGTTAATTTACCGCGCATTGTTATTGA
CCTGTTTTTTCAAGACTATTTTATCGCCTTTAAAAACGCCTGTCCCAATGTGACGCTCGAACTGTATGCCACCGATCGGA
AAGTCAATATTATCGAGTCCGGTTTTGACGCCGGCATTCGCTATTCGCAGGATGTGCCCAAAGAGATGATTGCCATCCCC
TTTGGCGAGAAACTATCGCTGATCCCGGTGGCCAGCCCGGACTATATACGCGAAGCCGGAGAGCCCGACACCCCGCAGTC
TTTAGTTAATTTCCGCTGCATTAACCGCTGTTTTCCTGGTGGGGAGAAGTACCGCTGGGAGTTTATTGGCCCCAGCGGCG
AGCTTAGCGAGGTCGCGGTTAAAGGCGATCTGGTCGTCGATGCCGATAGCGCAATGATCCAGGCCGCGGAGAGCGGATTA
GGCATCGCCTTTGTCTATCAGTCGCTGGTGACGCAGCAGCTGAGCGCGGGCAGCCTGGTCCATTTGTTACCCGACTACCG
CTATCCTGCCGACCATTTCTGCGTCTACTACCCAAGCCGGAAACATATTCCCGCCCCCCTGCGGGCCTTTATCGCCTGGG
TGATGGCGCAGAATAAAAATATCCTTGGTCAGCAGACCGCACGACACGGATCGCGGCCGGAAGATTAA

Upstream 100 bases:

>100_bases
CTTATTTTCCTTAATTGCTGAATGGCATTAAATATATACTTCCCTTTCATATTGATAACAATTAATCTATTCCGAACGCG
GTGTTAGCTGGAAATTAACA

Downstream 100 bases:

>100_bases
CTACAATTAACGTACATACCGTTAACCAATTTCTATCTTTCATCTTGAACTCCGGCGGTTATCCGGCATAAAATCGTTAG
AGCTCTAACGATATTGACAG

Product: putative LysR-family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MKTLPDLQQIEILILIVKHGSFRQAAKALNLSPPALTVAINHLEEKLGVRLLNRSTRSLSLTAVGEEFLNNITPVVNDYR
RVVDSLNYHRLTPEGVVKVNLPRIVIDLFFQDYFIAFKNACPNVTLELYATDRKVNIIESGFDAGIRYSQDVPKEMIAIP
FGEKLSLIPVASPDYIREAGEPDTPQSLVNFRCINRCFPGGEKYRWEFIGPSGELSEVAVKGDLVVDADSAMIQAAESGL
GIAFVYQSLVTQQLSAGSLVHLLPDYRYPADHFCVYYPSRKHIPAPLRAFIAWVMAQNKNILGQQTARHGSRPED

Sequences:

>Translated_315_residues
MKTLPDLQQIEILILIVKHGSFRQAAKALNLSPPALTVAINHLEEKLGVRLLNRSTRSLSLTAVGEEFLNNITPVVNDYR
RVVDSLNYHRLTPEGVVKVNLPRIVIDLFFQDYFIAFKNACPNVTLELYATDRKVNIIESGFDAGIRYSQDVPKEMIAIP
FGEKLSLIPVASPDYIREAGEPDTPQSLVNFRCINRCFPGGEKYRWEFIGPSGELSEVAVKGDLVVDADSAMIQAAESGL
GIAFVYQSLVTQQLSAGSLVHLLPDYRYPADHFCVYYPSRKHIPAPLRAFIAWVMAQNKNILGQQTARHGSRPED
>Mature_315_residues
MKTLPDLQQIEILILIVKHGSFRQAAKALNLSPPALTVAINHLEEKLGVRLLNRSTRSLSLTAVGEEFLNNITPVVNDYR
RVVDSLNYHRLTPEGVVKVNLPRIVIDLFFQDYFIAFKNACPNVTLELYATDRKVNIIESGFDAGIRYSQDVPKEMIAIP
FGEKLSLIPVASPDYIREAGEPDTPQSLVNFRCINRCFPGGEKYRWEFIGPSGELSEVAVKGDLVVDADSAMIQAAESGL
GIAFVYQSLVTQQLSAGSLVHLLPDYRYPADHFCVYYPSRKHIPAPLRAFIAWVMAQNKNILGQQTARHGSRPED

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787128, Length=311, Percent_Identity=32.7974276527331, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=29.96632996633, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1787589, Length=280, Percent_Identity=27.1428571428571, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1789440, Length=313, Percent_Identity=27.7955271565495, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI145693193, Length=298, Percent_Identity=26.8456375838926, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=27.1186440677966, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1789639, Length=288, Percent_Identity=24.3055555555556, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786448, Length=289, Percent_Identity=26.2975778546713, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789173, Length=298, Percent_Identity=23.1543624161074, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788706, Length=304, Percent_Identity=23.0263157894737, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI157672245, Length=174, Percent_Identity=31.0344827586207, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35166; Mature: 35166

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLPDLQQIEILILIVKHGSFRQAAKALNLSPPALTVAINHLEEKLGVRLLNRSTRSLS
CCCCCCHHHEEEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEE
LTAVGEEFLNNITPVVNDYRRVVDSLNYHRLTPEGVVKVNLPRIVIDLFFQDYFIAFKNA
EEEHHHHHHHCCCHHHHHHHHHHHCCCCEEECCCCEEEEECHHHHHHHHHHHHHHHHHCC
CPNVTLELYATDRKVNIIESGFDAGIRYSQDVPKEMIAIPFGEKLSLIPVASPDYIREAG
CCCCEEEEEEECCEEEEEECCCCCCCCCCCCCCHHHEECCCCCCEEEEECCCCHHHHHCC
EPDTPQSLVNFRCINRCFPGGEKYRWEFIGPSGELSEVAVKGDLVVDADSAMIQAAESGL
CCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEECCEEEECCHHHHHHHHCCC
GIAFVYQSLVTQQLSAGSLVHLLPDYRYPADHFCVYYPSRKHIPAPLRAFIAWVMAQNKN
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCC
ILGQQTARHGSRPED
CCHHHHHHCCCCCCC
>Mature Secondary Structure
MKTLPDLQQIEILILIVKHGSFRQAAKALNLSPPALTVAINHLEEKLGVRLLNRSTRSLS
CCCCCCHHHEEEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEE
LTAVGEEFLNNITPVVNDYRRVVDSLNYHRLTPEGVVKVNLPRIVIDLFFQDYFIAFKNA
EEEHHHHHHHCCCHHHHHHHHHHHCCCCEEECCCCEEEEECHHHHHHHHHHHHHHHHHCC
CPNVTLELYATDRKVNIIESGFDAGIRYSQDVPKEMIAIPFGEKLSLIPVASPDYIREAG
CCCCEEEEEEECCEEEEEECCCCCCCCCCCCCCHHHEECCCCCCEEEEECCCCHHHHHCC
EPDTPQSLVNFRCINRCFPGGEKYRWEFIGPSGELSEVAVKGDLVVDADSAMIQAAESGL
CCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEECCEEEECCHHHHHHHHCCC
GIAFVYQSLVTQQLSAGSLVHLLPDYRYPADHFCVYYPSRKHIPAPLRAFIAWVMAQNKN
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCC
ILGQQTARHGSRPED
CCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]