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The map label for this gene is paaK [H]

Identifier: 238894491

GI number: 238894491

Start: 2385200

End: 2386516

Strand: Direct

Name: paaK [H]

Synonym: KP1_2482

Alternate gene names: 238894491

Gene position: 2385200-2386516 (Clockwise)

Preceding gene: 238894490

Following gene: 238894492

Centisome position: 45.45

GC content: 58.24

Gene sequence:

>1317_bases
ATGATAACTACTACAAAATTAGATCCGATTGAAACCGCATCGCGTGACGAACTGCAGGCCCTGCAAACCCAGCGCCTGAA
ATGGACGCTGAAGCATGCGTACGAAAATGTGCCGATGTATCGCCGCAAATTCGACGCCGCTGGCGTGCACCCTGACGACT
TTCGGGAATTAAACGATCTGCAAAAATTCCCCTGCACCACCAAACAGGATCTGCGCGACAACTATCCCTTCGATACCTTC
GCGGTGCCGATGGAGCAGGTGGTGCGCATTCACGCCTCTTCCGGCACCACCGGCAAACCGACGGTGGTGGGATATACGCA
AAACGATATTGATAACTGGGCCAATATTGTCGCCCGTTCGCTGCGCGCGGCCGGTGGTTCAGCAAAAGATAAAATTCACG
TCGCCTACGGCTACGGCCTGTTTACCGGCGGCCTTGGCGCGCACTACGGCGCGGAACGTTTGGGCGCGACGGTGATCCCG
ATGTCCGGCGGACAGACCGAAAAACAGGCGCAGCTGATCCGCGATTTCCAGCCGGATATGATCATGGTGACGCCGTCCTA
CTGTCTGAATCTGATTGAAGAGCTGGAGCGCCAGATGGGCGGCGATGCCCGCGGCTGTTCATTGCGGGTCGGCGTCTTTG
GCGCTGAGCCGTGGACGCTGGCGATGCGCGCGGAAATCGAGCGCCGGCTGGGGATCACCGCCCTGGATATTTACGGTTTG
TCGGAAGTCATGGGACCGGGCGTAGCGATGGAGTGTCTGGAAACCGTTGACGGCCCGACTATCTGGGAAGACCACTTCTT
CCCGGAAATCGTCAACCCGGACGACGGTACGCCGCTGGAAGATGGCGAGCATGGTGAGCTGCTGTTTACCACCTTGACCA
AAGAAGCGCTGCCGGTGATCCGCTATCGTACCCGCGATCTGACGCGCCTGCTGCCGGGAACCGCGCGGACCATGCGCCGC
ATGGATCGCATCAGCGGACGCAGCGACGATATGCTGATTATCCGCGGGGTTAACGTCTTCCCCTCGCAGCTGGAAGAGGA
GATCCTCAAGTTTGAACACCTGGCGCCGCACTATCAGTTAGAGGTCAATCGCCGAGGTCATCTGGATTCGCTGGCGGTGC
GCGTTGAGCTGAAAGAGAGCGGGCTGGCGCTGAGTCATGAACAACGCTGCCAGATTTGCCATCAGTTGCGTCACCGTATT
AAGTCGATGGTCGGGATCTCCACCGATATTACTATCGTCAACTGCGGCAGCATTCCGCGCTCGGAAGGGAAAGCCTGTCG
GGTATTCGACCTGAGAAAAGCGGTGGTTAGCGGTTAA

Upstream 100 bases:

>100_bases
GCGGGCGCTATGCGCTGTGTACGATGTGTATTGGCGTGGGTCAGGGCATTGCCATGATCCTCGAGCGAGTGTGAGCTAAT
TTACCTGCGAGTACCCTACA

Downstream 100 bases:

>100_bases
TCCTCTCTCCGGCTGCGTGGCTGCGCGGCAGGCACCCGGCTGAAGCGTTTGCGCCGTCAGCCGGGGAGTTTCCTGTGCTA
TGATTCATAAAGGAAAAATA

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MITTTKLDPIETASRDELQALQTQRLKWTLKHAYENVPMYRRKFDAAGVHPDDFRELNDLQKFPCTTKQDLRDNYPFDTF
AVPMEQVVRIHASSGTTGKPTVVGYTQNDIDNWANIVARSLRAAGGSAKDKIHVAYGYGLFTGGLGAHYGAERLGATVIP
MSGGQTEKQAQLIRDFQPDMIMVTPSYCLNLIEELERQMGGDARGCSLRVGVFGAEPWTLAMRAEIERRLGITALDIYGL
SEVMGPGVAMECLETVDGPTIWEDHFFPEIVNPDDGTPLEDGEHGELLFTTLTKEALPVIRYRTRDLTRLLPGTARTMRR
MDRISGRSDDMLIIRGVNVFPSQLEEEILKFEHLAPHYQLEVNRRGHLDSLAVRVELKESGLALSHEQRCQICHQLRHRI
KSMVGISTDITIVNCGSIPRSEGKACRVFDLRKAVVSG

Sequences:

>Translated_438_residues
MITTTKLDPIETASRDELQALQTQRLKWTLKHAYENVPMYRRKFDAAGVHPDDFRELNDLQKFPCTTKQDLRDNYPFDTF
AVPMEQVVRIHASSGTTGKPTVVGYTQNDIDNWANIVARSLRAAGGSAKDKIHVAYGYGLFTGGLGAHYGAERLGATVIP
MSGGQTEKQAQLIRDFQPDMIMVTPSYCLNLIEELERQMGGDARGCSLRVGVFGAEPWTLAMRAEIERRLGITALDIYGL
SEVMGPGVAMECLETVDGPTIWEDHFFPEIVNPDDGTPLEDGEHGELLFTTLTKEALPVIRYRTRDLTRLLPGTARTMRR
MDRISGRSDDMLIIRGVNVFPSQLEEEILKFEHLAPHYQLEVNRRGHLDSLAVRVELKESGLALSHEQRCQICHQLRHRI
KSMVGISTDITIVNCGSIPRSEGKACRVFDLRKAVVSG
>Mature_438_residues
MITTTKLDPIETASRDELQALQTQRLKWTLKHAYENVPMYRRKFDAAGVHPDDFRELNDLQKFPCTTKQDLRDNYPFDTF
AVPMEQVVRIHASSGTTGKPTVVGYTQNDIDNWANIVARSLRAAGGSAKDKIHVAYGYGLFTGGLGAHYGAERLGATVIP
MSGGQTEKQAQLIRDFQPDMIMVTPSYCLNLIEELERQMGGDARGCSLRVGVFGAEPWTLAMRAEIERRLGITALDIYGL
SEVMGPGVAMECLETVDGPTIWEDHFFPEIVNPDDGTPLEDGEHGELLFTTLTKEALPVIRYRTRDLTRLLPGTARTMRR
MDRISGRSDDMLIIRGVNVFPSQLEEEILKFEHLAPHYQLEVNRRGHLDSLAVRVELKESGLALSHEQRCQICHQLRHRI
KSMVGISTDITIVNCGSIPRSEGKACRVFDLRKAVVSG

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=435, Percent_Identity=94.2528735632184, Blast_Score=862, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 49025; Mature: 49025

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITTTKLDPIETASRDELQALQTQRLKWTLKHAYENVPMYRRKFDAAGVHPDDFRELNDL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHH
QKFPCTTKQDLRDNYPFDTFAVPMEQVVRIHASSGTTGKPTVVGYTQNDIDNWANIVARS
HHCCCCCHHHHHCCCCCCHHHHCHHHHHEEECCCCCCCCCEEEEECHHHHHHHHHHHHHH
LRAAGGSAKDKIHVAYGYGLFTGGLGAHYGAERLGATVIPMSGGQTEKQAQLIRDFQPDM
HHHCCCCCCCEEEEEEECHHHCCCCCHHCCHHHHCCEEEECCCCCCHHHHHHHHHCCCCE
IMVTPSYCLNLIEELERQMGGDARGCSLRVGVFGAEPWTLAMRAEIERRLGITALDIYGL
EEECHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEHHHHHHHHHCCCEEEECCCH
SEVMGPGVAMECLETVDGPTIWEDHFFPEIVNPDDGTPLEDGEHGELLFTTLTKEALPVI
HHHHCCCHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHH
RYRTRDLTRLLPGTARTMRRMDRISGRSDDMLIIRGVNVFPSQLEEEILKFEHLAPHYQL
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEE
EVNRRGHLDSLAVRVELKESGLALSHEQRCQICHQLRHRIKSMVGISTDITIVNCGSIPR
EECCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
SEGKACRVFDLRKAVVSG
CCCCEEEHHHHHHHHHCC
>Mature Secondary Structure
MITTTKLDPIETASRDELQALQTQRLKWTLKHAYENVPMYRRKFDAAGVHPDDFRELNDL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHH
QKFPCTTKQDLRDNYPFDTFAVPMEQVVRIHASSGTTGKPTVVGYTQNDIDNWANIVARS
HHCCCCCHHHHHCCCCCCHHHHCHHHHHEEECCCCCCCCCEEEEECHHHHHHHHHHHHHH
LRAAGGSAKDKIHVAYGYGLFTGGLGAHYGAERLGATVIPMSGGQTEKQAQLIRDFQPDM
HHHCCCCCCCEEEEEEECHHHCCCCCHHCCHHHHCCEEEECCCCCCHHHHHHHHHCCCCE
IMVTPSYCLNLIEELERQMGGDARGCSLRVGVFGAEPWTLAMRAEIERRLGITALDIYGL
EEECHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEHHHHHHHHHCCCEEEECCCH
SEVMGPGVAMECLETVDGPTIWEDHFFPEIVNPDDGTPLEDGEHGELLFTTLTKEALPVI
HHHHCCCHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHH
RYRTRDLTRLLPGTARTMRRMDRISGRSDDMLIIRGVNVFPSQLEEEILKFEHLAPHYQL
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEE
EVNRRGHLDSLAVRVELKESGLALSHEQRCQICHQLRHRIKSMVGISTDITIVNCGSIPR
EECCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
SEGKACRVFDLRKAVVSG
CCCCEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]